Tipin (timeless interacting protein) - Rat Genome Database

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Gene: Tipin (timeless interacting protein) Rattus norvegicus
Analyze
Symbol: Tipin
Name: timeless interacting protein
RGD ID: 1564084
Description: Predicted to enable DNA binding activity. Predicted to be involved in several processes, including DNA integrity checkpoint signaling; cell cycle phase transition; and replication fork arrest. Predicted to act upstream of or within DNA damage checkpoint signaling and response to UV. Predicted to be located in cytoplasm and nucleus. Predicted to be part of chromatin and replication fork protection complex. Orthologous to human TIPIN (TIMELESS interacting protein); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363076; MGC114381; RGD1564084; similar to timeless-interacting protein; TIMELESS-interacting protein; UV98
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Tipin-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2864,780,813 - 64,801,358 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl864,780,828 - 64,801,352 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx870,295,265 - 70,315,733 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0868,567,853 - 68,588,333 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0866,437,844 - 66,458,313 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0869,753,363 - 69,768,640 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl869,753,373 - 69,768,305 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0869,463,024 - 69,477,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4868,480,152 - 68,502,451 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera864,192,517 - 64,207,800 (+)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-colchicine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
adenine  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
antimycin A  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
folic acid  (ISO)
hydroxyurea  (ISO)
L-methionine  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
mitomycin C  (ISO)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
pentachlorophenol  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
titanium dioxide  (ISO)
trimellitic anhydride  (ISO)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
DNA binding  (IBA,IEA)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12875843   PMID:17102137   PMID:17141802  


Genomics

Comparative Map Data
Tipin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2864,780,813 - 64,801,358 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl864,780,828 - 64,801,352 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx870,295,265 - 70,315,733 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0868,567,853 - 68,588,333 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0866,437,844 - 66,458,313 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0869,753,363 - 69,768,640 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl869,753,373 - 69,768,305 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0869,463,024 - 69,477,515 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4868,480,152 - 68,502,451 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera864,192,517 - 64,207,800 (+)NCBICelera
Cytogenetic Map8q24NCBI
TIPIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381566,336,191 - 66,386,717 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1566,336,191 - 66,386,746 (-)EnsemblGRCh38hg38GRCh38
GRCh371566,628,529 - 66,679,055 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361564,416,062 - 64,436,108 (-)NCBINCBI36Build 36hg18NCBI36
Celera1543,519,139 - 43,539,060 (-)NCBICelera
Cytogenetic Map15q22.31NCBI
HuRef1543,465,869 - 43,485,233 (-)NCBIHuRef
CHM1_11566,747,160 - 66,766,891 (-)NCBICHM1_1
T2T-CHM13v2.01564,157,927 - 64,208,168 (-)NCBIT2T-CHM13v2.0
Tipin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39964,188,776 - 64,212,704 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl964,188,863 - 64,212,706 (+)EnsemblGRCm39 Ensembl
GRCm38964,281,491 - 64,305,422 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl964,281,581 - 64,305,424 (+)EnsemblGRCm38mm10GRCm38
MGSCv37964,129,414 - 64,152,599 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36964,079,613 - 64,102,798 (+)NCBIMGSCv36mm8
Celera961,510,098 - 61,533,476 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map934.6NCBI
Tipin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554509,262,717 - 9,279,401 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554509,259,838 - 9,279,479 (+)NCBIChiLan1.0ChiLan1.0
TIPIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11559,768,356 - 59,814,887 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01545,290,350 - 45,310,335 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11563,566,463 - 63,586,090 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1563,566,463 - 63,585,717 (-)Ensemblpanpan1.1panPan2
TIPIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13030,641,557 - 30,657,353 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3030,641,555 - 30,657,260 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3030,573,853 - 30,589,657 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03030,836,561 - 30,856,011 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3030,836,561 - 30,855,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13030,766,159 - 30,785,588 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03030,829,419 - 30,845,237 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03031,071,478 - 31,086,206 (-)NCBIUU_Cfam_GSD_1.0
Tipin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640108,668,035 - 108,683,341 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647126,517,042 - 26,531,410 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647126,516,511 - 26,531,403 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIPIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1164,350,705 - 164,369,223 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11164,349,196 - 164,369,297 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21182,110,325 - 182,125,754 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TIPIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12617,194,859 - 17,214,671 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2617,198,734 - 17,214,810 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048124,233,775 - 124,254,001 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tipin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247816,301,764 - 6,324,870 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247816,300,661 - 6,325,394 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tipin
68 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:71
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000066973
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631271Lecl1Lens clarity QTL 10.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)81898416884531599Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)81933115293965294Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)82266233067662330Rat
2303564Gluco43Glucose level QTL 433blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)82613018771130187Rat
2303572Insul13Insulin level QTL 132blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)82613018771130187Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)82720571599103503Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)82720571599103503Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)82720571599103503Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)82950266570386295Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)83018886794457446Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83084815482460899Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83084815482460899Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83084815482460899Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83084815482460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)830848259105647037Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83555193880551938Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83646953599083736Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84071306682925667Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84071306693965294Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)84186687675097878Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)84186701070386132Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)84329616998968765Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)84329616998968765Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)84329616998968765Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)84329616998968765Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)84329616998968765Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)84329616998968765Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088626Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)84653172299083736Rat
2303570Gluco48Glucose level QTL 482blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)84980583194805831Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85009524982460899Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85009524982460899Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)851351728107062046Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)85396876598968765Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)85404374498968765Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)85423764485365202Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)85423764485365202Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)85423764499103503Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)854259986100382532Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat

Markers in Region
D8Got323  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2864,791,920 - 64,792,149 (+)MAPPERmRatBN7.2
Rnor_6.0869,759,212 - 69,759,440NCBIRnor6.0
Rnor_5.0869,468,087 - 69,468,315UniSTSRnor5.0
RGSC_v3.4868,492,179 - 68,492,407UniSTSRGSC3.4
Celera864,198,369 - 64,198,597UniSTS
Cytogenetic Map8q24UniSTS
RH139218  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2864,792,119 - 64,792,337 (+)MAPPERmRatBN7.2
Rnor_6.0869,759,411 - 69,759,628NCBIRnor6.0
Rnor_5.0869,468,286 - 69,468,503UniSTSRnor5.0
RGSC_v3.4868,492,378 - 68,492,595UniSTSRGSC3.4
Celera864,198,568 - 64,198,785UniSTS
RH 3.4 Map8809.9UniSTS
Cytogenetic Map8q24UniSTS
RH140249  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2864,786,364 - 64,786,584 (+)MAPPERmRatBN7.2
Rnor_6.0869,753,665 - 69,753,884NCBIRnor6.0
Rnor_5.0869,462,540 - 69,462,759UniSTSRnor5.0
RGSC_v3.4868,486,102 - 68,486,321UniSTSRGSC3.4
Celera864,192,818 - 64,193,037UniSTS
RH 3.4 Map8809.5UniSTS
Cytogenetic Map8q24UniSTS
BE100135  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.29113,543,816 - 113,543,968 (+)MAPPERmRatBN7.2
mRatBN7.2864,786,090 - 64,786,888 (+)MAPPERmRatBN7.2
mRatBN7.29113,694,228 - 113,694,380 (+)MAPPERmRatBN7.2
Rnor_6.05174,729 - 174,880NCBIRnor6.0
Rnor_6.0869,753,390 - 69,754,187NCBIRnor6.0
Rnor_5.05173,744 - 173,895UniSTSRnor5.0
RGSC_v3.49112,832,937 - 112,833,088UniSTSRGSC3.4
Celera864,192,544 - 64,193,340UniSTS
RH 3.4 Map9867.0UniSTS
Cytogenetic Map9q38UniSTS
Cytogenetic Map8q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 28 28 22 11 22 63 22 31 7
Low 1 15 29 19 8 19 8 10 11 13 10 4 8
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000066973   ⟹   ENSRNOP00000059833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl864,780,828 - 64,801,352 (+)Ensembl
Rnor_6.0 Ensembl869,753,373 - 69,768,305 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112754   ⟹   ENSRNOP00000083756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl864,781,184 - 64,801,352 (+)Ensembl
RefSeq Acc Id: NM_001025287   ⟹   NP_001020458
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2864,780,813 - 64,801,358 (+)NCBI
Rnor_6.0869,753,363 - 69,768,640 (+)NCBI
Rnor_5.0869,463,024 - 69,477,515 (+)NCBI
RGSC_v3.4868,480,152 - 68,502,451 (+)RGD
Celera864,192,517 - 64,207,800 (+)RGD
Sequence:
RefSeq Acc Id: XM_039081743   ⟹   XP_038937671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2864,781,104 - 64,801,355 (+)NCBI
RefSeq Acc Id: NP_001020458   ⟸   NM_001025287
- UniProtKB: Q4QR88 (UniProtKB/Swiss-Prot),   A6J5B9 (UniProtKB/TrEMBL),   F1LM96 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000059833   ⟸   ENSRNOT00000066973
RefSeq Acc Id: XP_038937671   ⟸   XM_039081743
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A0L4 (UniProtKB/TrEMBL),   F1LM96 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000083756   ⟸   ENSRNOT00000112754
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4QR88-F1-model_v2 AlphaFold Q4QR88 1-276 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564084 AgrOrtholog
BioCyc Gene G2FUF-30103 BioCyc
Ensembl Genes ENSRNOG00000037221 UniProtKB/TrEMBL
  ENSRNOG00000043068 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055024427 UniProtKB/Swiss-Prot
  ENSRNOG00060019471 UniProtKB/Swiss-Prot
  ENSRNOG00065006402 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000056239.3 UniProtKB/TrEMBL
  ENSRNOT00000066973 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000066973.4 UniProtKB/Swiss-Prot
  ENSRNOT00000112754 ENTREZGENE
  ENSRNOT00000112754.1 UniProtKB/TrEMBL
  ENSRNOT00055041995 UniProtKB/Swiss-Prot
  ENSRNOT00060033708 UniProtKB/Swiss-Prot
  ENSRNOT00065009847 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7387433 IMAGE-MGC_LOAD
InterPro Csm3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIPIN/Csm3/Swi3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:363076 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:114381 IMAGE-MGC_LOAD
NCBI Gene 363076 ENTREZGENE
PANTHER PTHR13220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TIMELESS-INTERACTING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Swi3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tipin PhenoGen
RatGTEx ENSRNOG00000037221 RatGTEx
  ENSRNOG00000043068 RatGTEx
  ENSRNOG00055024427 RatGTEx
  ENSRNOG00060019471 RatGTEx
  ENSRNOG00065006402 RatGTEx
UniProt A0A8I6A0L4 ENTREZGENE, UniProtKB/TrEMBL
  A6J5B9 ENTREZGENE, UniProtKB/TrEMBL
  F1LM96 ENTREZGENE, UniProtKB/TrEMBL
  F1M2N9_RAT UniProtKB/TrEMBL
  Q4QR88 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Tipin  timeless interacting protein  RGD1564084_predicted  similar to timeless-interacting protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564084_predicted  similar to timeless-interacting protein (predicted)  LOC363076  similar to timeless-interacting protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363076  similar to timeless-interacting protein      Symbol and Name status set to provisional 70820 PROVISIONAL