Cyp1a2 Rat (+)-artemisinin increases expression ISO Cyp1a2 (Mus musculus) 6480464 artemisinin results in increased expression of CYP1A2 mRNA CTD PMID:17962186 Cyp1a2 Rat (+)-artemisinin increases expression EXP 6480464 artemisinin results in increased expression of CYP1A2 mRNA CTD PMID:16919048 Cyp1a2 Rat (+)-artemisinin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 artemisinin results in decreased activity of CYP1A2 protein CTD PMID:11124226 Cyp1a2 Rat (+)-catechin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP1A2 mRNA CTD PMID:25663641 Cyp1a2 Rat (+)-epicatechin-3-O-gallate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP1A2 mRNA CTD PMID:25663641 Cyp1a2 Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP1A2 mRNA] CTD PMID:31150632 Cyp1a2 Rat (+/-)-Aegeline multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA CTD PMID:28843594 Cyp1a2 Rat (-)-cotinine increases activity ISO CYP1A2 (Homo sapiens) 6480464 Cotinine results in increased activity of CYP1A2 protein CTD PMID:16203240 Cyp1a2 Rat (-)-cotinine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Cotinine results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat (-)-epigallocatechin 3-gallate affects binding EXP 6480464 epigallocatechin gallate binds to CYP1A2 protein CTD PMID:23010222 Cyp1a2 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP1A2 mRNA CTD PMID:25663641 Cyp1a2 Rat (-)-selegiline affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Selegiline CTD PMID:16198659 Cyp1a2 Rat (-)-trans-epsilon-viniferin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 epsilon-viniferin results in decreased activity of CYP1A2 protein CTD PMID:12818727 Cyp1a2 Rat (1->4)-beta-D-glucan multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of CYP1A2 mRNA CTD PMID:36331819 Cyp1a2 Rat (1E,4E,8E)-alpha-humulene decreases activity EXP 6480464 humulene results in decreased activity of CYP1A2 protein CTD PMID:29074051 Cyp1a2 Rat (2-hydroxyphenyl)acetic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of coumarin] which results in increased abundance of 2-hydroxyphenylacetic acid CTD PMID:34334558 Cyp1a2 Rat (E,E)-germacrone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 germacrone results in decreased activity of CYP1A2 protein CTD PMID:23850985 Cyp1a2 Rat (R)-lipoic acid multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]] CTD PMID:21932800 Cyp1a2 Rat (R)-lipoic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 Cyp1a2 Rat (R,R,R)-alpha-tocopherol increases activity EXP 6480464 alpha-Tocopherol results in increased activity of CYP1A2 protein CTD PMID:15665910 Cyp1a2 Rat (R,R,R)-alpha-tocopherol multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 alpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA] CTD PMID:26102010 Cyp1a2 Rat (RS)-coclaurine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA CTD PMID:28843594 Cyp1a2 Rat (RS)-norcoclaurine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA CTD PMID:28843594 Cyp1a2 Rat (S)-coclaurine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA CTD PMID:28843594 Cyp1a2 Rat (S)-duloxetine hydrochloride multiple interactions EXP 6480464 [furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride and CYP1A2 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride CTD PMID:20669986 Cyp1a2 Rat (S)-naringenin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 naringenin results in decreased activity of CYP1A2 protein CTD PMID:21053930 and PMID:29753067 Cyp1a2 Rat (S)-nicotine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Nicotine results in increased expression of CYP1A2 protein CTD PMID:11849738 Cyp1a2 Rat (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of CYP1A2 mRNA CTD PMID:26463278 Cyp1a2 Rat (S)-nicotine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Nicotine results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of 1 more ... CTD PMID:9733665 Cyp1a2 Rat 1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of 1 more ... CTD PMID:9047321 Cyp1a2 Rat 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO Cyp1a2 (Mus musculus) 6480464 o and p'-DDT affects the expression of CYP1A2 mRNA CTD PMID:18925944 Cyp1a2 Rat 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO CYP1A2 (Homo sapiens) 6480464 o and p'-DDT results in increased expression of CYP1A2 mRNA CTD PMID:21924250 Cyp1a2 Rat 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane decreases activity EXP 6480464 2 and 2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased activity of CYP1A2 protein CTD PMID:15542068 Cyp1a2 Rat 1,2,3,7,8-Pentachlorodibenzodioxin increases expression ISO Cyp1a2 (Mus musculus) 6480464 1 more ... CTD PMID:23674508 Cyp1a2 Rat 1,2,3,7,8-Pentachlorodibenzofuran increases expression ISO Cyp1a2 (Mus musculus) 6480464 1 more ... CTD PMID:24713691 Cyp1a2 Rat 1,2,4,5-tetrachlorobenzene increases expression EXP 6480464 1 more ... CTD PMID:10696772 Cyp1a2 Rat 1,2,4-trichlorobenzene increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 1 more ... CTD PMID:7747284 Cyp1a2 Rat 1,2-dichlorobenzene increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:7747284 Cyp1a2 Rat 1,2-dichloroethane decreases expression ISO Cyp1a2 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of CYP1A2 mRNA CTD PMID:28189721 and PMID:28960355 Cyp1a2 Rat 1,2-dichloroethene affects expression EXP 6480464 1 and 2-dichloroethylene affects the expression of CYP1A2 protein CTD PMID:9493318 Cyp1a2 Rat 1,2-dichloroethene decreases activity EXP 6480464 1 and 2-dichloroethylene results in decreased activity of CYP1A2 protein CTD PMID:9671540 Cyp1a2 Rat 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of CYP1A2 mRNA CTD PMID:32387197 Cyp1a2 Rat 1,2-dimethylnaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1 and 2-dimethylnaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1,3,7-trimethyluric acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein binds to and results in increased metabolism of Caffeine] which results in increased chemical synthesis of 1 more ... CTD PMID:31132250 Cyp1a2 Rat 1,3-Dinitropyrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with POR protein] results in decreased metabolism of 1 and 3-dinitropyrene CTD PMID:11113705 Cyp1a2 Rat 1,3-Dinitropyrene affects metabolic processing EXP 6480464 CYP1A2 protein affects the metabolism of 1 and 3-dinitropyrene CTD PMID:2180560 Cyp1a2 Rat 1,4-dichlorobenzene increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 4-dichlorobenzene CTD PMID:7747284 Cyp1a2 Rat 1,4-dimethylnaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1 and 4-dimethylnaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1,4-naphthoquinone increases expression ISO CYP1A2 (Homo sapiens) 6480464 1 and 4-naphthoquinone results in increased expression of CYP1A2 mRNA CTD PMID:18602459 Cyp1a2 Rat 1,4-naphthoquinone increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of 1 and 4-naphthoquinone CTD PMID:16243959 Cyp1a2 Rat 1,6-dimethylnaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1 and 6-dimethylnaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1,6-Dinitropyrene affects metabolic processing EXP 6480464 CYP1A2 protein affects the metabolism of 1 and 6-dinitropyrene CTD PMID:2180560 Cyp1a2 Rat 1,7-dimethylxanthine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 1 and 7-dimethylxanthine CTD PMID:1302044 Cyp1a2 Rat 1,7-dimethylxanthine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein binds to and results in increased metabolism of Caffeine] which results in increased chemical synthesis of 1 more ... CTD PMID:19215233 and PMID:31132250 Cyp1a2 Rat 1,7-dimethylxanthine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of 1 and 7-dimethylxanthine CTD PMID:19215233 Cyp1a2 Rat 1,7-dimethylxanthine increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of 1 and 7-dimethylxanthine CTD PMID:15980104 Cyp1a2 Rat 1,7-dimethylxanthine increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of 1 and 7-dimethylxanthine CTD PMID:1302044 Cyp1a2 Rat 1,7-phenanthroline multiple interactions EXP 6480464 1 and 7-phenanthroline inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein] CTD PMID:17967931 Cyp1a2 Rat 1,7-phenanthroline increases expression EXP 6480464 1 and 7-phenanthroline results in increased expression of CYP1A2 protein CTD PMID:17967931 Cyp1a2 Rat 1,8-Dinitropyrene affects metabolic processing EXP 6480464 CYP1A2 protein affects the metabolism of 1 and 8-dinitropyrene CTD PMID:2180560 Cyp1a2 Rat 1-(1,3-benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 stiripentol results in decreased activity of CYP1A2 protein CTD PMID:16022579 Cyp1a2 Rat 1-Aminopyrene increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 1-aminopyrene CTD PMID:15728263 Cyp1a2 Rat 1-benzofuran decreases activity ISO CYP1A2 (Homo sapiens) 6480464 benzofuran analog results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1-hydroxyanthraquinone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1-hydroxyanthraquinone results in decreased activity of CYP1A2 protein CTD PMID:33438235 Cyp1a2 Rat 1-methyl-7H-xanthine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1-methylxanthine results in decreased activity of CYP1A2 protein CTD PMID:11465391 Cyp1a2 Rat 1-methyl-7H-xanthine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of 1 and 7-dimethylxanthine] which results in increased chemical synthesis of 1-methylxanthine CTD PMID:19215233 Cyp1a2 Rat 1-methylnaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1-methylnaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1-Methylpyrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with SULT1A1 protein] results in increased susceptibility to 1-methylpyrene CTD PMID:33035519 Cyp1a2 Rat 1-naphthol increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of 1-naphthol CTD PMID:16243959 Cyp1a2 Rat 1-naphthol affects binding ISO CYP1A2 (Homo sapiens) 6480464 1-naphthol binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat 1-naphthol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1-naphthol results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 1-naphthyl isothiocyanate multiple interactions EXP 6480464 [1-Naphthylisothiocyanate co-treated with 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:15598703 Cyp1a2 Rat 1-naphthyl isothiocyanate multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA CTD PMID:27344345 Cyp1a2 Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of CYP1A2 mRNA CTD PMID:20551477 Cyp1a2 Rat 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP1A2 protein CTD PMID:15598703 Cyp1a2 Rat 1-nitropyrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] and CYP1A2 affects the reaction [1-nitropyrene results in increased mutagenesis of HPRT1 gene] CTD PMID:10727902 and PMID:18493746 Cyp1a2 Rat 1-nitropyrene affects response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 affects the susceptibility to 1-nitropyrene CTD PMID:10727902 Cyp1a2 Rat 1-nitropyrene multiple interactions EXP 6480464 1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat 17alpha-ethynylestradiol increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Ethinyl Estradiol CTD PMID:15304426 Cyp1a2 Rat 17alpha-ethynylestradiol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Ethinyl Estradiol results in decreased activity of CYP1A2 protein CTD PMID:18816299 Cyp1a2 Rat 17alpha-ethynylestradiol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein] which results in decreased metabolism of tizanidine more ... CTD PMID:16198659 and PMID:16291717 Cyp1a2 Rat 17beta-estradiol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of CYP1A2 mRNA more ... CTD PMID:16790556 more ... Cyp1a2 Rat 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CYP1A2 mRNA CTD PMID:31119341 and PMID:32145629 Cyp1a2 Rat 17beta-estradiol decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Estradiol results in decreased expression of CYP1A2 mRNA CTD PMID:28357125 Cyp1a2 Rat 17beta-estradiol increases expression ISO CYP1A2 (Homo sapiens) 6480464 Estradiol results in increased expression of CYP1A2 mRNA CTD PMID:19619570 Cyp1a2 Rat 17beta-estradiol increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Estradiol CTD PMID:16790556 Cyp1a2 Rat 17beta-estradiol increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Estradiol CTD PMID:15961252 Cyp1a2 Rat 2'-deoxyguanosine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine] and CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 Cyp1a2 Rat 2,2',3,3',6,6'-hexachlorobiphenyl decreases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:28431184 Cyp1a2 Rat 2,2',3,3',6,6'-hexachlorobiphenyl increases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:28431184 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl decreases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 results in decreased susceptibility to 2 more ... CTD PMID:21571617 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:21851831 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:3302669 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases activity EXP 6480464 2 more ... CTD PMID:16835634 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:16835634 and PMID:17160104 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:20961953 and PMID:28433925 Cyp1a2 Rat 2,2',4,4',5,5'-hexachlorobiphenyl increases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:15743714 Cyp1a2 Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:32679240 Cyp1a2 Rat 2,2',5,5'-tetrachlorobiphenyl increases expression ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:21703328 Cyp1a2 Rat 2,2',5,5'-tetrachlorobiphenyl affects response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the susceptibility to 2 more ... CTD PMID:27913846 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl decreases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 results in decreased susceptibility to 2 more ... CTD PMID:21571617 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:17342196 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl decreases activity EXP 6480464 2 more ... CTD PMID:15659567 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:23674508 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl increases activity ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:10986007 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:18493746 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:15659567 Cyp1a2 Rat 2,3',4,4',5-Pentachlorobiphenyl multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:20961953 Cyp1a2 Rat 2,3,3',4,4',5,5'-Heptachlorobiphenyl increases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:15743714 Cyp1a2 Rat 2,3,3',4,4',5-Hexachlorobiphenyl multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:18493746 Cyp1a2 Rat 2,3,3',4,4',5-Hexachlorobiphenyl increases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:23674508 Cyp1a2 Rat 2,3,3',4,4',5-Hexachlorobiphenyl decreases activity EXP 6480464 2 more ... CTD PMID:15659567 Cyp1a2 Rat 2,3,3',4,4',5-Hexachlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:15659567 Cyp1a2 Rat 2,3,3',4,4',5-Hexachlorobiphenyl increases activity ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:10986007 Cyp1a2 Rat 2,3,4,3',4'-Pentachlorobiphenyl multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:18493746 Cyp1a2 Rat 2,3,4,3',4'-Pentachlorobiphenyl decreases activity EXP 6480464 2 more ... CTD PMID:15659567 Cyp1a2 Rat 2,3,4,3',4'-Pentachlorobiphenyl decreases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 results in decreased susceptibility to 2 more ... CTD PMID:21571617 Cyp1a2 Rat 2,3,4,3',4'-Pentachlorobiphenyl increases activity ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:10986007 Cyp1a2 Rat 2,3,4,3',4'-Pentachlorobiphenyl multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:20961953 Cyp1a2 Rat 2,3,4,3',4'-Pentachlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:15659567 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17342195 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran increases expression ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:20705892 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran increases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:23674508 and PMID:24713691 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran increases activity EXP 6480464 2 more ... CTD PMID:17160103 and PMID:20705892 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran increases expression EXP 6480464 2 more ... CTD PMID:20705892 and PMID:21724226 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran increases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:20705892 Cyp1a2 Rat 2,3,4,7,8-Pentachlorodibenzofuran affects abundance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the abundance of 2 more ... CTD PMID:10448125 and PMID:9240455 Cyp1a2 Rat 2,3,7,8-tetrabromodibenzodioxine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:27604104 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] more ... CTD PMID:11064004 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Cyp1a2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CYP1A2 mRNA CTD PMID:20819909 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA and Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein CTD PMID:11064004 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases activity EXP 6480464 Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein CTD PMID:12062927 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP1A2 mRNA CTD PMID:15034205 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA and Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein CTD PMID:10568693 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO CYP1A2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein CTD PMID:16426572 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CYP1A2 mRNA CTD PMID:22298810 and PMID:31511937 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO CYP1A2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of CYP1A2 mRNA CTD PMID:22298810 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO Cyp1a2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein CTD PMID:10986007 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases activity EXP 6480464 Tetrachlorodibenzodioxin results in decreased activity of CYP1A2 protein CTD PMID:15659567 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] more ... CTD PMID:11585058 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 affects the susceptibility to Tetrachlorodibenzodioxin and CYP1A2 protein affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:16636061 and PMID:21095216 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects abundance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the abundance of Tetrachlorodibenzodioxin CTD PMID:10448125 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein affects the abundance of Tetrachlorodibenzodioxin] inhibits the reaction [CYP1A1 protein results in increased metabolism of Tetrachlorodibenzodioxin] more ... CTD PMID:11043581 more ... Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased activity of CYP1A2 protein CTD PMID:15659567 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:16636061 Cyp1a2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Cyp1a2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP1A2 more ... CTD PMID:11043581 more ... Cyp1a2 Rat 2,3,7,8-Tetrachlorodibenzofuran increases expression EXP 6480464 2 more ... CTD PMID:20705892 more ... Cyp1a2 Rat 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:20702594 more ... Cyp1a2 Rat 2,3,7,8-Tetrachlorodibenzofuran multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 AHR protein promotes the reaction [2 more ... CTD PMID:25768209 Cyp1a2 Rat 2,3,7,8-Tetrachlorodibenzofuran increases activity EXP 6480464 2 more ... CTD PMID:20705892 Cyp1a2 Rat 2,3,7,8-Tetrachlorodibenzofuran increases activity ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:20705892 Cyp1a2 Rat 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:20705892 Cyp1a2 Rat 2,3-dihydrobenzofuran decreases activity ISO CYP1A2 (Homo sapiens) 6480464 coumaran results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein CTD PMID:18079364 Cyp1a2 Rat 2,4,6-Triphenyl-1-hexene decreases expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:18560529 Cyp1a2 Rat 2,4-D increases expression EXP 6480464 2 and 4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A2 mRNA CTD PMID:10910964 Cyp1a2 Rat 2,4-diaminotoluene increases expression EXP 6480464 2 and 4-diaminotoluene results in increased expression of CYP1A2 protein CTD PMID:8685904 Cyp1a2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression EXP 6480464 2 more ... CTD PMID:22331496 Cyp1a2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Cyp1a2 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Cyp1a2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression ISO CYP1A2 (Homo sapiens) 6480464 2 more ... CTD PMID:19270788 Cyp1a2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions EXP 6480464 [CYP1A2 protein results in increased oxidation of 2 more ... CTD PMID:21673328 Cyp1a2 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases oxidation EXP 6480464 CYP1A2 protein results in increased oxidation of 2 more ... CTD PMID:21673328 Cyp1a2 Rat 2,4-dinitrophenol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2 and 4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat 2,4-dinitrophenol multiple interactions EXP 6480464 2 and 4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat 2,6-dimethylnaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2 and 6-dimethylnaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Verapamil results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Praziquantel CTD PMID:12920490 Cyp1a2 Rat 2-acetamidofluorene increases hydrolysis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 results in increased hydrolysis of 2-Acetylaminofluorene CTD PMID:2334931 Cyp1a2 Rat 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of CYP1A2 protein CTD PMID:28245158 Cyp1a2 Rat 2-acetamidofluorene increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 2-Acetylaminofluorene CTD PMID:15450435 Cyp1a2 Rat 2-acetamidofluorene affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 2-Acetylaminofluorene CTD PMID:2655891 Cyp1a2 Rat 2-acetamidofluorene increases expression ISO Cyp1a2 (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA CTD PMID:16381673 Cyp1a2 Rat 2-acetamidofluorene decreases expression EXP 6480464 2-Acetylaminofluorene analog results in decreased expression of CYP1A2 protein and 2-Acetylaminofluorene results in decreased expression of CYP1A2 protein CTD PMID:15916741 Cyp1a2 Rat 2-acetamidofluorene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 NR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA] CTD PMID:16381673 Cyp1a2 Rat 2-amino-2-deoxy-D-galactopyranose decreases expression EXP 6480464 Galactosamine results in decreased expression of CYP1A2 protein CTD PMID:16208626 Cyp1a2 Rat 2-Amino-3-methyl-9H-pyrido[2,3-b]indole increases expression EXP 6480464 2-amino-3-methyl-9H-pyrido(2 more ... CTD PMID:8902619 Cyp1a2 Rat 2-Amino-3-methyl-9H-pyrido[2,3-b]indole increases expression ISO CYP1A2 (Homo sapiens) 6480464 2-amino-3-methyl-9H-pyrido(2 and 3-b)indole results in increased expression of CYP1A2 mRNA CTD PMID:27644595 Cyp1a2 Rat 2-Amino-3-methyl-9H-pyrido[2,3-b]indole multiple interactions EXP 6480464 lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2 more ... CTD PMID:8902619 Cyp1a2 Rat 2-Amino-3-methyl-9H-pyrido[2,3-b]indole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of and results in increased hydroxylation of 2-amino-3-methyl-9H-pyrido(2 more ... CTD PMID:14729582 and PMID:28160022 Cyp1a2 Rat 2-amino-4,6-dinitrotoluene affects expression EXP 6480464 2-amino-4 and 6-dinitrotoluene affects the expression of CYP1A2 mRNA CTD PMID:21346803 Cyp1a2 Rat 2-Amino-9H-pyrido[2,3-b]indole multiple interactions EXP 6480464 CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-9H-pyrido(2 and 3-b)indole CTD PMID:1913651 Cyp1a2 Rat 2-Amino-9H-pyrido[2,3-b]indole increases expression ISO CYP1A2 (Homo sapiens) 6480464 2-amino-9H-pyrido(2 and 3-b)indole results in increased expression of CYP1A2 mRNA CTD PMID:27644595 Cyp1a2 Rat 2-Amino-9H-pyrido[2,3-b]indole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with NAT2 gene polymorphism] promotes the reaction [2-amino-9H-pyrido(2 more ... CTD PMID:1913651 more ... Cyp1a2 Rat 2-benzoxazolinone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 benzoxazolone results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2-chlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2-chlorobiphenyl results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2-hydroxy-17beta-estradiol increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol CTD PMID:16790556 Cyp1a2 Rat 2-hydroxy-17beta-estradiol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Carbaryl inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol] more ... CTD PMID:16790556 Cyp1a2 Rat 2-hydroxychrysophanol increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of 2-hydroxychrysophanol CTD PMID:29698620 Cyp1a2 Rat 2-hydroxychrysophanol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of chrysophanic acid] which results in increased chemical synthesis of 2-hydroxychrysophanol CTD PMID:29698620 Cyp1a2 Rat 2-Methoxynaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2-methoxynaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2-methyl-1H-indole increases expression ISO CYP1A2 (Homo sapiens) 6480464 2-methylindole results in increased expression of CYP1A2 protein CTD PMID:31201936 Cyp1a2 Rat 2-methyl-6-(phenylethynyl)pyridine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 6-methyl-2-(phenylethynyl)pyridine results in decreased activity of CYP1A2 protein CTD PMID:15193955 Cyp1a2 Rat 2-methylnaphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2-methylnaphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2-naphthol increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of 2-naphthol CTD PMID:16243959 Cyp1a2 Rat 2-naphthol affects binding ISO CYP1A2 (Homo sapiens) 6480464 2-naphthol binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat 2-naphthol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 2-naphthol results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 2-naphthylamine increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 2-Naphthylamine CTD PMID:15450435 Cyp1a2 Rat 2-nitroanisole increases expression EXP 6480464 2-nitroanisole results in increased expression of CYP1A2 and 2-nitroanisole results in increased expression of CYP1A2 protein CTD PMID:11409192 and PMID:16601807 Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:16049271 more ... Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl affects expression ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:31563530 Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:20702594 more ... Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:16049271 more ... Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:20961953 more ... Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl increases activity EXP 6480464 3 more ... CTD PMID:16628245 Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl decreases activity EXP 6480464 3 more ... CTD PMID:15659567 Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:15659567 Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl increases activity ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:10986007 Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:12635099 more ... Cyp1a2 Rat 3,3',4,4',5-pentachlorobiphenyl decreases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 results in decreased susceptibility to 3 more ... CTD PMID:21571617 Cyp1a2 Rat 3,3',4,4'-tetrachlorobiphenyl decreases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 results in decreased susceptibility to 3 more ... CTD PMID:21571617 Cyp1a2 Rat 3,3',4,4'-tetrachlorobiphenyl increases expression ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:31733235 Cyp1a2 Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:12635099 Cyp1a2 Rat 3,3',4,4'-tetrachlorobiphenyl increases expression ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:12117779 and PMID:19467301 Cyp1a2 Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:20961953 Cyp1a2 Rat 3,3',5-triiodo-L-thyronine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Triiodothyronine results in increased expression of CYP1A2 mRNA CTD PMID:28478156 Cyp1a2 Rat 3,3',5-triiodo-L-thyronine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Triiodothyronine affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] and Triiodothyronine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein] CTD PMID:28478156 Cyp1a2 Rat 3,3'-diindolylmethane increases expression ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:15672752 and PMID:19770484 Cyp1a2 Rat 3,3'-diindolylmethane increases expression EXP 6480464 3 and 3'-diindolylmethane results in increased expression of CYP1A2 protein CTD PMID:8384853 Cyp1a2 Rat 3,3'-diindolylmethane decreases activity ISO CYP1A2 (Homo sapiens) 6480464 3 and 3'-diindolylmethane results in decreased activity of CYP1A2 protein CTD PMID:19770484 Cyp1a2 Rat 3,3'-diindolylmethane increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 3 and 3'-diindolylmethane CTD PMID:16544949 Cyp1a2 Rat 3,3'-diindolylmethane multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [3 more ... CTD PMID:16544949 and PMID:19770484 Cyp1a2 Rat 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol decreases expression EXP 6480464 fluorotelomer alcohols results in decreased expression of CYP1A2 mRNA CTD PMID:38903859 Cyp1a2 Rat 3,4,5,3',4',5'-Hexachlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:15659567 Cyp1a2 Rat 3,4,5,3',4',5'-Hexachlorobiphenyl multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 3 more ... CTD PMID:20961953 Cyp1a2 Rat 3,4,5,3',4',5'-Hexachlorobiphenyl decreases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 results in decreased susceptibility to 3 more ... CTD PMID:21571617 Cyp1a2 Rat 3,4,5,3',4',5'-Hexachlorobiphenyl decreases activity EXP 6480464 3 more ... CTD PMID:15659567 Cyp1a2 Rat 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine increases expression ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:23810796 Cyp1a2 Rat 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 3 more ... CTD PMID:28160022 Cyp1a2 Rat 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 results in increased activity of 3 more ... CTD PMID:2334931 Cyp1a2 Rat 3,4-dichloroaniline increases expression ISO CYP1A2 (Homo sapiens) 6480464 3 more ... CTD PMID:21784029 Cyp1a2 Rat 3,4-dihydroxybenzoic acid multiple interactions EXP 6480464 protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein] CTD PMID:15302093 Cyp1a2 Rat 3,4-methylenedioxymethamphetamine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased activity of CYP1A2 protein CTD PMID:24211539 Cyp1a2 Rat 3,5-xylenol increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 3 and 5-xylenol analog CTD PMID:27665777 Cyp1a2 Rat 3,5-xylenol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased oxidation of 3 and 5-xylenol analog] which results in increased abundance of 4-(methylsulfinyl)phenol analog CTD PMID:27665777 Cyp1a2 Rat 3-(indol-3-yl)pyruvic acid increases expression ISO CYP1A2 (Homo sapiens) 6480464 indol-3-yl pyruvic acid results in increased expression of CYP1A2 mRNA CTD PMID:38641223 Cyp1a2 Rat 3-(Methylthio)-1-propene increases expression EXP 6480464 allyl methyl sulfide results in increased expression of CYP1A2 protein CTD PMID:16000231 Cyp1a2 Rat 3-Amino-1-methyl-5H-pyrido[4,3-b]indole affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 3-amino-1-methyl-5H-pyrido(4 and 3-b)indole CTD PMID:2655891 Cyp1a2 Rat 3-Amino-1-methyl-5H-pyrido[4,3-b]indole increases expression ISO CYP1A2 (Homo sapiens) 6480464 3-amino-1-methyl-5H-pyrido(4 and 3-b)indole results in increased expression of CYP1A2 mRNA CTD PMID:27644595 Cyp1a2 Rat 3-Amino-1-methyl-5H-pyrido[4,3-b]indole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 3-amino-1-methyl-5H-pyrido(4 and 3-b)indole CTD PMID:28160022 Cyp1a2 Rat 3-Amino-1-methyl-5H-pyrido[4,3-b]indole increases activity ISO Cyp1a2 (Mus musculus) 6480464 3-amino-1-methyl-5H-pyrido(4 and 3-b)indole results in increased activity of CYP1A2 protein CTD PMID:12744663 Cyp1a2 Rat 3-Amino-1-methyl-5H-pyrido[4,3-b]indole affects response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the susceptibility to 3-amino-1-methyl-5H-pyrido(4 and 3-b)indole CTD PMID:19140158 Cyp1a2 Rat 3-isobutyl-1-methyl-7H-xanthine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1-Methyl-3-isobutylxanthine results in decreased activity of CYP1A2 protein CTD PMID:11465391 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases activity EXP 6480464 CYP1A2 results in increased activity of 2-amino-3-methylimidazo(4 and 5-f)quinoline CTD PMID:11752233 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases expression ISO CYP1A2 (Homo sapiens) 6480464 2-amino-3-methylimidazo(4 and 5-f)quinoline results in increased expression of CYP1A2 mRNA CTD PMID:27644595 and PMID:31542801 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein co-treated with 2-amino-3-methylimidazo(4 and 5-f)quinoline] results in increased mutagenesis of APRT gene CTD PMID:2023932 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 2-amino-3-methylimidazo(4 and 5-f)quinoline CTD PMID:2655891 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 2-amino-3-methylimidazo(4 more ... CTD PMID:15728263 and PMID:2334931 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine affects response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the susceptibility to 2-amino-3-methylimidazo(4 and 5-f)quinoline CTD PMID:2023932 Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3-methylimidazo(4 more ... CTD PMID:10503888 more ... Cyp1a2 Rat 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine multiple interactions EXP 6480464 Quercetin inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3-methylimidazo(4 and 5-f)quinoline] CTD PMID:11752233 Cyp1a2 Rat 3-methylcholanthrene increases activity ISO Cyp1a2 (Mus musculus) 6480464 Methylcholanthrene results in increased activity of CYP1A2 protein CTD PMID:16639589 and PMID:4054433 Cyp1a2 Rat 3-methylcholanthrene increases response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 gene mutant form results in increased susceptibility to Methylcholanthrene CTD PMID:32726451 Cyp1a2 Rat 3-methylcholanthrene increases expression ISO CYP1A2 (Homo sapiens) 6480464 Methylcholanthrene results in increased expression of CYP1A2 mRNA and Methylcholanthrene results in increased expression of CYP1A2 protein CTD PMID:12107646 more ... Cyp1a2 Rat 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of CYP1A2 mRNA and Methylcholanthrene results in increased expression of CYP1A2 protein CTD PMID:10476907 more ... Cyp1a2 Rat 3-methylcholanthrene increases activity EXP 6480464 Methylcholanthrene results in increased activity of CYP1A2 protein CTD PMID:15302093 more ... Cyp1a2 Rat 3-methylcholanthrene increases activity ISO CYP1A2 (Homo sapiens) 6480464 Methylcholanthrene results in increased activity of CYP1A2 protein CTD PMID:19022236 more ... Cyp1a2 Rat 3-methylcholanthrene multiple interactions EXP 6480464 [[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1 more ... CTD PMID:11999409 more ... Cyp1a2 Rat 3-methylcholanthrene affects response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 affects the susceptibility to Methylcholanthrene CTD PMID:19772856 Cyp1a2 Rat 3-methylcholanthrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A2 mRNA more ... CTD PMID:15448115 more ... Cyp1a2 Rat 3-methylcholanthrene increases expression ISO Cyp1a2 (Mus musculus) 6480464 Methylcholanthrene results in increased expression of CYP1A2 mRNA and Methylcholanthrene results in increased expression of CYP1A2 protein CTD PMID:11356909 more ... Cyp1a2 Rat 3-methylcholanthrene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA more ... CTD PMID:21498875 more ... Cyp1a2 Rat 3-Methylchrysene increases expression ISO CYP1A2 (Homo sapiens) 6480464 3-methylchrysene results in increased expression of CYP1A2 mRNA CTD PMID:31087746 Cyp1a2 Rat 3-methylquinoline decreases activity ISO CYP1A2 (Homo sapiens) 6480464 3-methylquinoline results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 3-Nitrofluoranthene increases expression ISO CYP1A2 (Homo sapiens) 6480464 3-nitrofluoranthene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 Cyp1a2 Rat 3-phenoxybenzoic acid affects binding ISO CYP1A2 (Homo sapiens) 6480464 3-phenoxybenzoic acid binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of CYP1A2 mRNA CTD PMID:19162173 Cyp1a2 Rat 4',5,7-trihydroxy-3'-methoxyflavone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:20553787 Cyp1a2 Rat 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone increases activity EXP 6480464 musk ketone results in increased activity of CYP1A2 protein CTD PMID:10630706 Cyp1a2 Rat 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone increases expression EXP 6480464 musk ketone results in increased expression of CYP1A2 protein CTD PMID:10630706 Cyp1a2 Rat 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone increases expression ISO Cyp1a2 (Mus musculus) 6480464 musk ketone results in increased expression of CYP1A2 mRNA CTD PMID:9441723 Cyp1a2 Rat 4,4'-sulfonyldiphenol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 bisphenol S results in decreased activity of CYP1A2 protein CTD PMID:33312107 Cyp1a2 Rat 4-(methylsulfinyl)phenol increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of 4-(methylsulfinyl)phenol analog CTD PMID:27665777 Cyp1a2 Rat 4-(methylsulfinyl)phenol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased oxidation of 3 and 5-xylenol analog] which results in increased abundance of 4-(methylsulfinyl)phenol analog CTD PMID:27665777 Cyp1a2 Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:11774366 Cyp1a2 Rat 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:15728263 Cyp1a2 Rat 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1 and 2-diphenyl-1-butene CTD PMID:29285606 Cyp1a2 Rat 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1 more ... CTD PMID:29285606 Cyp1a2 Rat 4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenol increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of 1-(4-hydroxyphenyl)-1 and 2-diphenyl-1-butene CTD PMID:29285606 Cyp1a2 Rat 4-chlorobiphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 4-chlorobiphenyl results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat 4-Hydroxy-N-desmethyltamoxifen increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen CTD PMID:29285606 Cyp1a2 Rat 4-Hydroxy-N-desmethyltamoxifen multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen] which results in increased abundance of 4-hydroxy-N-desmethyltamoxifen metabolite CTD PMID:29285606 Cyp1a2 Rat 4-Hydroxybenzyl isothiocyanate multiple interactions EXP 6480464 4-hydroxybenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein] CTD PMID:22664424 Cyp1a2 Rat 4-Hydroxybenzyl isothiocyanate increases expression EXP 6480464 4-hydroxybenzyl isothiocyanate results in increased expression of CYP1A2 mRNA CTD PMID:22664424 Cyp1a2 Rat 4-hydroxychalcone affects chemical synthesis EXP 6480464 CYP1A2 protein affects the chemical synthesis of 4-hydroxychalcone CTD PMID:15863696 Cyp1a2 Rat 4-hydroxynon-2-enal multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1 more ... CTD PMID:21766881 Cyp1a2 Rat 4-hydroxyphenyl retinamide increases expression ISO Cyp1a2 (Mus musculus) 6480464 Fenretinide results in increased expression of CYP1A2 mRNA CTD PMID:28973697 Cyp1a2 Rat 4-Ipomeanol increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 4-ipomeanol CTD PMID:15892579 Cyp1a2 Rat 4-Methylchrysene increases expression ISO CYP1A2 (Homo sapiens) 6480464 4-methylchrysene results in increased expression of CYP1A2 mRNA CTD PMID:31087746 Cyp1a2 Rat 4-nitroaniline increases activity EXP 6480464 4-nitroaniline analog results in increased activity of CYP1A2 protein CTD PMID:9545601 Cyp1a2 Rat 4-nitroaniline increases expression EXP 6480464 4-nitroaniline analog results in increased expression of CYP1A2 mRNA and 4-nitroaniline analog results in increased expression of CYP1A2 protein CTD PMID:7553614 and PMID:9545601 Cyp1a2 Rat 4-nitrophenol increases hydroxylation EXP 6480464 CYP1A2 protein results in increased hydroxylation of 4-nitrophenol CTD PMID:11911841 Cyp1a2 Rat 4-phenoxyphenol affects binding ISO CYP1A2 (Homo sapiens) 6480464 4-phenoxyphenol binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat 5,7-dihydroxy-4'-methoxyflavone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 acacetin results in decreased activity of CYP1A2 protein CTD PMID:21053930 Cyp1a2 Rat 5,7-dihydroxy-4'-methoxyflavone decreases activity EXP 6480464 acacetin results in decreased activity of CYP1A2 protein CTD PMID:32738202 Cyp1a2 Rat 5-(2-chloroethyl)-4-methylthiazole decreases expression EXP 6480464 Chlormethiazole results in decreased expression of CYP1A2 mRNA CTD PMID:10751552 Cyp1a2 Rat 5-aza-2'-deoxycytidine increases expression ISO Cyp1a2 (Mus musculus) 6480464 Decitabine results in increased expression of CYP1A2 mRNA CTD PMID:30503582 Cyp1a2 Rat 5-aza-2'-deoxycytidine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Decitabine results in increased expression of CYP1A2 mRNA CTD PMID:19274061 and PMID:28357125 Cyp1a2 Rat 5-azacytidine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:12927368 Cyp1a2 Rat 5-azacytidine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Azacitidine results in increased expression of CYP1A2 mRNA CTD PMID:12927368 Cyp1a2 Rat 5-Hydroxyflavone increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 5-hydroxyflavone CTD PMID:30964977 Cyp1a2 Rat 5-Hydroxyflavone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 5-hydroxyflavone results in decreased activity of CYP1A2 protein CTD PMID:21053930 Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 Omeprazole results in increased expression of CYP1A2 mRNA and Omeprazole results in increased expression of CYP1A2 protein CTD PMID:12040753 more ... Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Omeprazole results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression EXP 6480464 Omeprazole results in increased expression of CYP1A2 mRNA and Omeprazole results in increased expression of CYP1A2 protein CTD PMID:19118567 more ... Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions EXP 6480464 [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA CTD PMID:22687989 Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases activity ISO CYP1A2 (Homo sapiens) 6480464 Omeprazole results in increased activity of CYP1A2 promoter and Omeprazole results in increased activity of CYP1A2 protein CTD PMID:18502397 more ... Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Omeprazole results in decreased activity of CYP1A2 protein CTD PMID:16035375 Cyp1a2 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin more ... CTD PMID:15802389 more ... Cyp1a2 Rat 5-methoxyindole decreases activity ISO Cyp1a2 (Mus musculus) 6480464 5-methoxyindole results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat 5-Methylchrysene increases expression ISO CYP1A2 (Homo sapiens) 6480464 5-methylchrysene results in increased expression of CYP1A2 mRNA CTD PMID:31087746 Cyp1a2 Rat 5-methyltryptamine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [5-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin CTD PMID:26599973 Cyp1a2 Rat 5-methyltryptamine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 5-methyltryptamine analog results in decreased activity of CYP1A2 protein CTD PMID:26599973 Cyp1a2 Rat 6-bromoindirubin-3'-oxime increases expression ISO CYP1A2 (Homo sapiens) 6480464 6-bromoindirubin-3'-oxime results in increased expression of CYP1A2 mRNA CTD PMID:26259606 Cyp1a2 Rat 6-bromoindirubin-3'-oxime multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 6-bromoindirubin-3'-oxime results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:26259606 Cyp1a2 Rat 6-chrysenamine increases expression ISO CYP1A2 (Homo sapiens) 6480464 6-chrysenamine results in increased expression of CYP1A2 mRNA CTD PMID:12107646 Cyp1a2 Rat 6-chrysenamine increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 6-chrysenamine CTD PMID:15728263 Cyp1a2 Rat 6-Methylchrysene increases expression ISO CYP1A2 (Homo sapiens) 6480464 6-methylchrysene results in increased expression of CYP1A2 mRNA CTD PMID:31087746 Cyp1a2 Rat 6-Nitrobenzo[a]pyrene increases expression ISO CYP1A2 (Homo sapiens) 6480464 6-nitrobenzo(a)pyrene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 Cyp1a2 Rat 6-Nitrochrysene increases expression ISO CYP1A2 (Homo sapiens) 6480464 6-nitrochrysene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 Cyp1a2 Rat 7,12-dimethyltetraphene increases expression ISO CYP1A2 (Homo sapiens) 6480464 9 more ... CTD PMID:17183067 more ... Cyp1a2 Rat 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:36863560 Cyp1a2 Rat 7,12-dimethyltetraphene multiple interactions EXP 6480464 9 more ... CTD PMID:18678235 Cyp1a2 Rat 7,12-dimethyltetraphene increases activity ISO CYP1A2 (Homo sapiens) 6480464 9 more ... CTD PMID:17183067 Cyp1a2 Rat 7,12-dimethyltetraphene increases activity ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased activity of 9 more ... CTD PMID:15606143 Cyp1a2 Rat 7,12-dimethyltetraphene increases activity EXP 6480464 9 more ... CTD PMID:16054776 Cyp1a2 Rat 7,12-dimethyltetraphene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9 more ... CTD PMID:8961944 Cyp1a2 Rat 7,12-dimethyltetraphene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2-((2 more ... CTD PMID:17183067 more ... Cyp1a2 Rat 7-hydroxyflavone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 7-hydroxyflavone results in decreased activity of CYP1A2 protein CTD PMID:21053930 and PMID:29753067 Cyp1a2 Rat 7-Nitrobenz[a]anthracene increases expression ISO CYP1A2 (Homo sapiens) 6480464 7-nitrobenzanthracene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 Cyp1a2 Rat 7H-Dibenzo[c,g]carbazole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of and results in increased activity of 7H-dibenzo(c and g)carbazole CTD PMID:15534862 Cyp1a2 Rat 9-phenanthrol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol CTD PMID:27137136 Cyp1a2 Rat 9-phenanthrol increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of 9-phenanthrol CTD PMID:27137136 Cyp1a2 Rat acenaphthene increases activity ISO Cyp1a2 (Mus musculus) 6480464 acenaphthene results in increased activity of CYP1A2 protein CTD PMID:8001243 Cyp1a2 Rat acenaphthene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat acenaphthylene increases expression ISO Cyp1a2 (Mus musculus) 6480464 acenaphthylene results in increased expression of CYP1A2 mRNA and acenaphthylene results in increased expression of CYP1A2 protein CTD PMID:8001243 Cyp1a2 Rat acenaphthylene increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of acenaphthylene CTD PMID:25642975 Cyp1a2 Rat acenaphthylene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat acenaphthylene increases activity ISO Cyp1a2 (Mus musculus) 6480464 acenaphthylene results in increased activity of CYP1A2 protein CTD PMID:10977129 and PMID:8001243 Cyp1a2 Rat acenocoumarol affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Acenocoumarol CTD PMID:11918509 Cyp1a2 Rat acephate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [fenarimol co-treated with acephate] affects the expression of CYP1A2 protein and [fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A2 protein CTD PMID:17686559 Cyp1a2 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of CYP1A2 mRNA CTD PMID:31881176 Cyp1a2 Rat acetone multiple interactions EXP 6480464 Acetone promotes the reaction [Toluene results in increased expression of CYP1A2 protein] CTD PMID:8996725 Cyp1a2 Rat acetone increases expression EXP 401900656 acetone increased expression of Cyp1a2 protein in thoracic aorta of rats RGD Cyp1a2 Rat Acetyl tributyl citrate decreases expression ISO Cyp1a2 (Mus musculus) 6480464 2-acetyltributylcitrate results in decreased expression of CYP1A2 mRNA CTD PMID:37055963 Cyp1a2 Rat aconitine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Fluvoxamine results in decreased activity of CYP1A2 protein] which results in increased chemical synthesis of Aconitine metabolite CTD PMID:21277363 Cyp1a2 Rat acridines decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Acridines analog results in decreased activity of CYP1A2 protein CTD PMID:16120190 Cyp1a2 Rat acridines multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Acridines analog inhibits the reaction [CYP1A2 protein results in increased oxidation of vadimezan] CTD PMID:16120190 Cyp1a2 Rat actinomycin D multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA] more ... CTD PMID:21262253 Cyp1a2 Rat Aescin increases expression EXP 401900603 Aescin increased expression of Cyp1a2 mRNA in rat liver RGD Cyp1a2 Rat Aescin increases activity EXP 401900603 Aescin increased activity of cyp1a2 protein enzyme in rat plasma RGD Cyp1a2 Rat afimoxifene increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of afimoxifene CTD PMID:29285606 Cyp1a2 Rat afimoxifene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of afimoxifene] which results in increased abundance of afimoxifene metabolite CTD PMID:29285606 Cyp1a2 Rat aflatoxin B1 increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of Aflatoxin B1 CTD PMID:15988000 Cyp1a2 Rat aflatoxin B1 multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CYP1A2 mRNA] CTD PMID:35063475 Cyp1a2 Rat aflatoxin B1 decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of CYP1A2 mRNA CTD PMID:27153756 Cyp1a2 Rat aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CYP1A2 mRNA CTD PMID:26260870 Cyp1a2 Rat aflatoxin B1 increases expression ISO CYP1A2 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of CYP1A2 mRNA CTD PMID:21994236 and PMID:32234424 Cyp1a2 Rat aflatoxin B1 increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Aflatoxin B1 CTD PMID:22743290 and PMID:36442682 Cyp1a2 Rat aflatoxin B1 multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Aflatoxin B1 more ... CTD PMID:20707407 more ... Cyp1a2 Rat aflatoxin B1 decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of CYP1A2 mRNA CTD PMID:19770486 and PMID:35063475 Cyp1a2 Rat aflatoxin B1 increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to Aflatoxin B1 CTD PMID:11189750 more ... Cyp1a2 Rat aflatoxin B1 exo-8,9-epoxide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin B1-2 and 3-oxide CTD PMID:20707407 Cyp1a2 Rat Aflatoxin G1 increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to aflatoxin G1 CTD PMID:11189750 Cyp1a2 Rat Aflatoxin G1 increases expression ISO CYP1A2 (Homo sapiens) 6480464 aflatoxin G1 results in increased expression of CYP1A2 protein CTD PMID:36997055 Cyp1a2 Rat aflatoxin M1 multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased abundance of Aflatoxin M1 and [CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of Aflatoxin M1 CTD PMID:20707407 and PMID:36442682 Cyp1a2 Rat alachlor increases expression EXP 6480464 alachlor results in increased expression of CYP1A2 protein CTD PMID:11850968 Cyp1a2 Rat albendazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 Albendazole results in increased expression of CYP1A2 mRNA CTD PMID:12451431 Cyp1a2 Rat albendazole affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Albendazole CTD PMID:12920490 Cyp1a2 Rat aldehydo-D-glucose multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31776611 Cyp1a2 Rat alizarin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 alizarin results in decreased activity of CYP1A2 protein CTD PMID:12379470 and PMID:33438235 Cyp1a2 Rat all-trans-retinoic acid increases expression ISO CYP1A2 (Homo sapiens) 6480464 Tretinoin results in increased expression of CYP1A2 mRNA CTD PMID:16985168 Cyp1a2 Rat all-trans-retinoic acid decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of CYP1A2 mRNA CTD PMID:16882163 and PMID:7697808 Cyp1a2 Rat all-trans-retinoic acid decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Tretinoin results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat allocryptopine increases expression ISO CYP1A2 (Homo sapiens) 6480464 allocryptopine results in increased expression of CYP1A2 mRNA CTD PMID:21419197 Cyp1a2 Rat almotriptan decreases methylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of almotriptan CTD PMID:12642466 Cyp1a2 Rat Aloe emodin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 aloe emodin results in decreased activity of CYP1A2 protein CTD PMID:27633141 and PMID:33438235 Cyp1a2 Rat alpha-linolenic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 alpha-Linolenic Acid results in decreased activity of CYP1A2 protein CTD PMID:16978661 Cyp1a2 Rat alpha-methyltryptamine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [indopan analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin and [indopan results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin CTD PMID:26599973 Cyp1a2 Rat alpha-methyltryptamine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 indopan analog results in decreased activity of CYP1A2 protein and indopan results in decreased activity of CYP1A2 protein CTD PMID:26599973 Cyp1a2 Rat alpha-naphthoflavone increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of alpha-naphthoflavone CTD PMID:17702393 Cyp1a2 Rat alpha-naphthoflavone affects binding ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein binds to alpha-naphthoflavone CTD PMID:27966929 Cyp1a2 Rat alpha-naphthoflavone increases expression ISO CYP1A2 (Homo sapiens) 6480464 alpha-naphthoflavone results in increased expression of CYP1A2 mRNA and alpha-naphthoflavone results in increased expression of CYP1A2 protein CTD PMID:19828881 and PMID:28887089 Cyp1a2 Rat alpha-naphthoflavone affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of alpha-naphthoflavone CTD PMID:2180560 Cyp1a2 Rat alpha-naphthoflavone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 alpha-naphthoflavone results in decreased activity of CYP1A2 protein CTD PMID:15306208 more ... Cyp1a2 Rat alpha-naphthoflavone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin more ... CTD PMID:18493746 more ... Cyp1a2 Rat alpha-naphthoflavone increases expression EXP 6480464 alpha-naphthoflavone results in increased expression of CYP1A2 protein CTD PMID:20448087 Cyp1a2 Rat alpha-naphthoflavone multiple interactions EXP 6480464 [2-amino-3 more ... CTD PMID:18493746 and PMID:20448087 Cyp1a2 Rat alpha-naphthoflavone multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]] and [alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde CTD PMID:21766881 and PMID:21932800 Cyp1a2 Rat ametryn multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of ametryne] CTD PMID:8971136 Cyp1a2 Rat ametryn increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of ametryne CTD PMID:8971136 Cyp1a2 Rat amiodarone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Amiodarone results in decreased activity of CYP1A2 protein CTD PMID:16449812 and PMID:26599973 Cyp1a2 Rat amiodarone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin CTD PMID:26599973 Cyp1a2 Rat amiodarone decreases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 Cyp1a2 Rat amitraz increases expression EXP 6480464 amitraz results in increased expression of CYP1A2 protein CTD PMID:15350676 and PMID:31029719 Cyp1a2 Rat amitriptyline increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 Amitriptyline results in increased metabolism of CYP1A2 protein and CYP1A2 protein results in increased metabolism of Amitriptyline CTD PMID:18359012 and PMID:27320963 Cyp1a2 Rat amitriptyline multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Amitriptyline CTD PMID:23397584 Cyp1a2 Rat amitriptylinoxide increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of amitriptyline N-oxide CTD PMID:27320963 Cyp1a2 Rat amodiaquine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Amodiaquine results in decreased activity of CYP1A2 protein CTD PMID:11124226 Cyp1a2 Rat amodiaquine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of Amodiaquine] which results in increased abundance of desethylamodiaquine more ... CTD PMID:26599973 and PMID:31629065 Cyp1a2 Rat amodiaquine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Amodiaquine CTD PMID:31629065 Cyp1a2 Rat amphetamine increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Amphetamine analog CTD PMID:29277574 Cyp1a2 Rat amphetamine decreases methylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of Amphetamine analog CTD PMID:29277574 Cyp1a2 Rat amphetamine affects chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the chemical synthesis of Amphetamine CTD PMID:15294457 Cyp1a2 Rat ampicillin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 Cyp1a2 Rat andrographolide decreases expression ISO CYP1A2 (Homo sapiens) 6480464 andrographolide results in decreased expression of CYP1A2 mRNA CTD PMID:19041297 Cyp1a2 Rat andrographolide multiple interactions EXP 6480464 andrographolide affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline] CTD PMID:20096675 Cyp1a2 Rat andrographolide increases expression EXP 6480464 andrographolide results in increased expression of CYP1A2 mRNA CTD PMID:19041297 Cyp1a2 Rat andrographolide increases expression ISO Cyp1a2 (Mus musculus) 6480464 andrographolide results in increased expression of CYP1A2 mRNA CTD PMID:17825862 Cyp1a2 Rat andrographolide multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1A2 mRNA and [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA CTD PMID:17825862 and PMID:19737545 Cyp1a2 Rat angelicin increases expression ISO Cyp1a2 (Mus musculus) 6480464 angelicin results in increased expression of CYP1A2 protein CTD PMID:18692084 Cyp1a2 Rat aniline multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of [norharman co-treated with aniline] CTD PMID:15279827 Cyp1a2 Rat aniline increases expression EXP 6480464 aniline analog results in increased expression of CYP1A2 mRNA and aniline analog results in increased expression of CYP1A2 protein CTD PMID:16639589 Cyp1a2 Rat aniline increases activity EXP 6480464 aniline analog results in increased activity of CYP1A2 protein CTD PMID:16639589 Cyp1a2 Rat anthra[1,9-cd]pyrazol-6(2H)-one increases expression ISO CYP1A2 (Homo sapiens) 6480464 pyrazolanthrone results in increased expression of CYP1A2 mRNA CTD PMID:17959153 Cyp1a2 Rat anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] and resveratrol inhibits the reaction [pyrazolanthrone results in increased expression of CYP1A2 mRNA] CTD PMID:17959153 Cyp1a2 Rat anthracen-2-amine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYB5A protein promotes the reaction [CYP1A2 protein results in increased activity of 2-anthramine] CTD PMID:15728263 Cyp1a2 Rat anthracen-2-amine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 2-anthramine CTD PMID:2655891 Cyp1a2 Rat anthracen-2-amine increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 2-anthramine CTD PMID:15728263 Cyp1a2 Rat anthracene increases activity ISO Cyp1a2 (Mus musculus) 6480464 anthracene results in increased activity of CYP1A2 protein CTD PMID:8001243 Cyp1a2 Rat anthracene affects binding ISO CYP1A2 (Homo sapiens) 6480464 anthracene binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat anthracene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat anthracene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 alyssin inhibits the reaction [anthracene results in increased activity of CYP1A2 protein] and sulforaphane inhibits the reaction [anthracene results in increased activity of CYP1A2 protein] CTD PMID:19362136 Cyp1a2 Rat anthracene increases activity ISO CYP1A2 (Homo sapiens) 6480464 anthracene results in increased activity of CYP1A2 protein CTD PMID:19362136 Cyp1a2 Rat anthracene-1,8,9-triol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Anthralin results in decreased activity of CYP1A2 protein CTD PMID:33438235 Cyp1a2 Rat apigenin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Apigenin results in decreased activity of CYP1A2 protein CTD PMID:20806393 more ... Cyp1a2 Rat arachidonic acid increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Arachidonic Acid CTD PMID:12675279 Cyp1a2 Rat arachidonic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Arachidonic Acid results in decreased activity of CYP1A2 protein CTD PMID:16978661 Cyp1a2 Rat Aranidipine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 aranidipine results in decreased activity of CYP1A2 protein CTD PMID:10805063 Cyp1a2 Rat arecoline increases activity EXP 6480464 Arecoline analog results in increased activity of CYP1A2 protein CTD PMID:25056785 Cyp1a2 Rat aristolochic acid A multiple interactions EXP 6480464 [1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A2 mRNA more ... CTD PMID:26845733 Cyp1a2 Rat aristolochic acid A increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of aristolochic acid I CTD PMID:26845733 Cyp1a2 Rat aristolochic acid A increases metabolic processing EXP 6480464 CYP1A2 protein results in increased metabolism of aristolochic acid I CTD PMID:21362632 and PMID:26845733 Cyp1a2 Rat aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of CYP1A2 mRNA CTD PMID:26845733 Cyp1a2 Rat aristolochic acid A increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of aristolochic acid I metabolite CTD PMID:22086975 Cyp1a2 Rat aristolochic acid A multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased oxidation of aristolochic acid I] which results in increased chemical synthesis of aristolochic acid I metabolite more ... CTD PMID:22086975 and PMID:26845733 Cyp1a2 Rat aristolochic acid A increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of aristolochic acid I CTD PMID:22086975 Cyp1a2 Rat aristolochic acid A multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]] more ... CTD PMID:21932800 Cyp1a2 Rat aristolochic acid A increases abundance EXP 6480464 CYP1A2 protein results in increased abundance of aristolochic acid I metabolite CTD PMID:21362632 Cyp1a2 Rat Aroclor 1254 increases activity EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased activity of CYP1A2 protein CTD PMID:11713002 and PMID:8471063 Cyp1a2 Rat Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA and Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 protein CTD PMID:11163329 more ... Cyp1a2 Rat Aroclor 1254 increases expression ISO CYP1A2 (Homo sapiens) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA and Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 protein CTD PMID:16049271 more ... Cyp1a2 Rat Aroclor 1254 increases expression ISO Cyp1a2 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA CTD PMID:25270620 Cyp1a2 Rat Aroclor 1254 affects response to substance ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 affects the susceptibility to Chlorodiphenyl (54% Chlorine) CTD PMID:19772856 Cyp1a2 Rat arsane multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP1A2 mRNA CTD PMID:35747940 Cyp1a2 Rat arsenic atom multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Estradiol co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of CYP1A2 mRNA CTD PMID:35747940 Cyp1a2 Rat arsenite(3-) multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:23369756 Cyp1a2 Rat arsenite(3-) multiple interactions EXP 6480464 arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] more ... CTD PMID:22159698 Cyp1a2 Rat arsenous acid multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] and Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein] CTD PMID:35872050 Cyp1a2 Rat arsenous acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] and Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:35872050 Cyp1a2 Rat Artemisin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 artemisin results in decreased activity of CYP1A2 protein CTD PMID:16261361 Cyp1a2 Rat asenapine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Asenapine results in decreased activity of CYP1A2 protein CTD PMID:32941854 Cyp1a2 Rat asenapine decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Asenapine results in decreased expression of CYP1A2 mRNA CTD PMID:32941854 Cyp1a2 Rat aspartame increases activity EXP 6480464 Aspartame results in increased activity of CYP1A2 protein CTD PMID:16937917 Cyp1a2 Rat atazanavir sulfate multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Atazanavir Sulfate] results in decreased expression of CYP1A2 mRNA CTD PMID:33819548 Cyp1a2 Rat Atipamezole multiple interactions EXP 6480464 atipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]] more ... CTD PMID:16510159 Cyp1a2 Rat atovaquone increases activity ISO CYP1A2 (Homo sapiens) 6480464 Atovaquone results in increased activity of CYP1A2 protein CTD PMID:11124226 Cyp1a2 Rat atrazine increases activity EXP 6480464 Atrazine results in increased activity of CYP1A2 protein CTD PMID:9711812 Cyp1a2 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of CYP1A2 gene CTD PMID:35440735 Cyp1a2 Rat atrazine increases expression ISO Cyp1a2 (Mus musculus) 6480464 Atrazine results in increased expression of CYP1A2 mRNA CTD PMID:26775023 Cyp1a2 Rat atrazine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA and Lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA] CTD PMID:26775023 and PMID:36216167 Cyp1a2 Rat atrazine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Atrazine results in increased expression of CYP1A2 mRNA CTD PMID:22310298 Cyp1a2 Rat atrazine increases activity ISO CYP1A2 (Homo sapiens) 6480464 Atrazine results in increased activity of CYP1A2 protein CTD PMID:22310298 Cyp1a2 Rat Avasimibe decreases activity ISO CYP1A2 (Homo sapiens) 6480464 avasimibe results in decreased activity of CYP1A2 protein CTD PMID:15333513 Cyp1a2 Rat azoxystrobin increases expression ISO CYP1A2 (Homo sapiens) 6480464 azoxystrobin results in increased expression of CYP1A2 mRNA and azoxystrobin results in increased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat baicalein increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of baicalein CTD PMID:19666078 Cyp1a2 Rat baicalein decreases activity ISO CYP1A2 (Homo sapiens) 6480464 baicalein results in decreased activity of CYP1A2 protein CTD PMID:21053930 and PMID:29753067 Cyp1a2 Rat baicalein multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein CTD PMID:19666078 Cyp1a2 Rat baicalin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 3' more ... CTD PMID:26204831 Cyp1a2 Rat baicalin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA] and resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein] CTD PMID:26204831 Cyp1a2 Rat baicalin increases expression ISO CYP1A2 (Homo sapiens) 6480464 baicalin results in increased expression of CYP1A2 mRNA and baicalin results in increased expression of CYP1A2 protein CTD PMID:26204831 Cyp1a2 Rat baicalin increases expression ISO Cyp1a2 (Mus musculus) 6480464 baicalin results in increased expression of CYP1A2 mRNA and baicalin results in increased expression of CYP1A2 protein CTD PMID:26204831 Cyp1a2 Rat benidipine increases expression ISO CYP1A2 (Homo sapiens) 6480464 benidipine results in increased expression of CYP1A2 mRNA CTD PMID:27732883 Cyp1a2 Rat benoxaprofen increases expression EXP 6480464 benoxaprofen results in increased expression of CYP1A2 protein CTD PMID:2069584 Cyp1a2 Rat benzene decreases expression EXP 6480464 Benzene results in decreased expression of CYP1A2 and Benzene results in decreased expression of CYP1A2 protein CTD PMID:8517779 and PMID:9010585 Cyp1a2 Rat benzo[a]pyrene increases expression ISO CYP1A2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of CYP1A2 mRNA and Benzo(a)pyrene results in increased expression of CYP1A2 protein CTD PMID:10496959 more ... Cyp1a2 Rat benzo[a]pyrene decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of CYP1A2 mRNA CTD PMID:32234424 Cyp1a2 Rat benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CYP1A2 mRNA and Benzo(a)pyrene results in increased expression of CYP1A2 protein CTD PMID:16510159 more ... Cyp1a2 Rat benzo[a]pyrene increases expression ISO Cyp1a2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of CYP1A2 mRNA and Benzo(a)pyrene results in increased expression of CYP1A2 protein CTD PMID:11171528 more ... Cyp1a2 Rat benzo[a]pyrene decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of CYP1A2 mRNA CTD PMID:15034205 Cyp1a2 Rat benzo[a]pyrene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased activity of CYP1A2 protein CTD PMID:11162773 Cyp1a2 Rat benzo[a]pyrene increases activity EXP 6480464 Benzo(a)pyrene results in increased activity of CYP1A2 mRNA and Benzo(a)pyrene results in increased activity of CYP1A2 protein CTD PMID:21505853 Cyp1a2 Rat benzo[a]pyrene increases activity ISO CYP1A2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased activity of CYP1A2 protein CTD PMID:19202560 Cyp1a2 Rat benzo[a]pyrene increases activity ISO Cyp1a2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased activity of CYP1A2 protein CTD PMID:15863256 and PMID:18321868 Cyp1a2 Rat benzo[a]pyrene increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Benzo(a)pyrene CTD PMID:2791199 Cyp1a2 Rat benzo[a]pyrene increases hydrolysis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydrolysis of Benzo(a)pyrene CTD PMID:19919601 Cyp1a2 Rat benzo[a]pyrene affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Benzo(a)pyrene CTD PMID:20542099 Cyp1a2 Rat benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:16510159 more ... Cyp1a2 Rat benzo[a]pyrene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with sodium bichromate] results in decreased expression of CYP1A2 mRNA more ... CTD PMID:15034205 more ... Cyp1a2 Rat benzo[a]pyrene affects metabolic processing ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the metabolism of Benzo(a)pyrene CTD PMID:16256281 Cyp1a2 Rat benzo[a]pyrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2-oxohexyl isothiocyanate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein] more ... CTD PMID:10496959 more ... Cyp1a2 Rat benzo[b]fluoranthene increases expression ISO Cyp1a2 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of CYP1A2 mRNA CTD PMID:12117779 Cyp1a2 Rat benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA and [chrysene co-treated with Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A2 mRNA CTD PMID:18711122 and PMID:37189300 Cyp1a2 Rat benzo[b]fluoranthene increases expression ISO CYP1A2 (Homo sapiens) 6480464 benzo(b)fluoranthene results in increased expression of CYP1A2 mRNA CTD PMID:16269432 more ... Cyp1a2 Rat benzo[b]fluoranthene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA and [propiconazole co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A2 mRNA CTD PMID:17690111 and PMID:30293151 Cyp1a2 Rat benzo[b]fluoranthene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 benzo(b)fluoranthene results in decreased activity of CYP1A2 protein CTD PMID:11162773 Cyp1a2 Rat benzo[b]fluoranthene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat Benzo[b]fluorene increases expression ISO CYP1A2 (Homo sapiens) 6480464 benzo(b)fluorene results in increased expression of CYP1A2 mRNA CTD PMID:17253728 Cyp1a2 Rat Benzo[b]fluorene increases expression EXP 6480464 benzo(b)fluorene results in increased expression of CYP1A2 mRNA CTD PMID:38903859 Cyp1a2 Rat benzo[c]phenanthrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 Cyp1a2 Rat benzo[c]phenanthrene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 Cyp1a2 Rat Benzo[k]fluoranthene increases expression ISO CYP1A2 (Homo sapiens) 6480464 benzo(k)fluoranthene results in increased expression of CYP1A2 mRNA and benzo(k)fluoranthene results in increased expression of CYP1A2 protein CTD PMID:11162773 more ... Cyp1a2 Rat Benzo[k]fluoranthene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat Benzo[k]fluoranthene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 mRNA] and sodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 protein] CTD PMID:11162773 Cyp1a2 Rat Benzo[k]fluoranthene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 benzo(k)fluoranthene results in decreased activity of CYP1A2 protein CTD PMID:11162773 Cyp1a2 Rat benzofurans decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Benzofurans analog results in decreased activity of CYP1A2 protein CTD PMID:15659567 Cyp1a2 Rat benzofurans decreases activity EXP 6480464 Benzofurans analog results in decreased activity of CYP1A2 protein CTD PMID:15659567 Cyp1a2 Rat benzyl isothiocyanate increases expression EXP 6480464 benzyl isothiocyanate results in increased expression of CYP1A2 mRNA CTD PMID:22664424 Cyp1a2 Rat benzyl isothiocyanate multiple interactions EXP 6480464 benzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein] CTD PMID:22664424 Cyp1a2 Rat benzylideneacetone increases oxidation EXP 6480464 CYP1A2 protein results in increased oxidation of benzylideneacetone CTD PMID:15863696 Cyp1a2 Rat berberine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Berberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA] CTD PMID:22342832 Cyp1a2 Rat bergomottin increases expression ISO Cyp1a2 (Mus musculus) 6480464 bergamottin results in increased expression of CYP1A2 protein CTD PMID:18692084 Cyp1a2 Rat Besigomsin decreases activity ISO Cyp1a2 (Mus musculus) 6480464 schizandrol B results in decreased activity of CYP1A2 protein CTD PMID:25753323 Cyp1a2 Rat beta-carboline multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of [norharman co-treated with aniline] CTD PMID:15279827 Cyp1a2 Rat beta-carotene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein] and Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]] CTD PMID:16970932 Cyp1a2 Rat beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of CYP1A2 mRNA and beta-Naphthoflavone results in increased expression of CYP1A2 protein CTD PMID:10463385 more ... Cyp1a2 Rat beta-naphthoflavone increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene mutant form results in increased susceptibility to beta-Naphthoflavone CTD PMID:29180065 Cyp1a2 Rat beta-naphthoflavone increases activity EXP 6480464 beta-Naphthoflavone results in increased activity of CYP1A2 protein CTD PMID:10463385 more ... Cyp1a2 Rat beta-naphthoflavone increases activity ISO Cyp1a2 (Mus musculus) 6480464 beta-Naphthoflavone results in increased activity of CYP1A2 protein CTD PMID:21745492 Cyp1a2 Rat beta-naphthoflavone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased activity of CYP1A2 protein CTD PMID:21053930 Cyp1a2 Rat beta-naphthoflavone multiple interactions EXP 6480464 [2-amino-3 more ... CTD PMID:18164116 more ... Cyp1a2 Rat beta-naphthoflavone increases activity ISO CYP1A2 (Homo sapiens) 6480464 beta-Naphthoflavone results in increased activity of CYP1A2 protein CTD PMID:10923861 more ... Cyp1a2 Rat beta-naphthoflavone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] more ... CTD PMID:10936227 more ... Cyp1a2 Rat beta-naphthoflavone increases expression ISO CYP1A2 (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of CYP1A2 mRNA and beta-Naphthoflavone results in increased expression of CYP1A2 protein CTD PMID:12584154 more ... Cyp1a2 Rat beta-naphthoflavone multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA more ... CTD PMID:19737545 more ... Cyp1a2 Rat beta-naphthoflavone increases expression ISO Cyp1a2 (Mus musculus) 6480464 beta-Naphthoflavone results in increased expression of CYP1A2 mRNA and beta-Naphthoflavone results in increased expression of CYP1A2 protein CTD PMID:19737545 more ... Cyp1a2 Rat bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of CYP1A2 mRNA CTD PMID:16648578 Cyp1a2 Rat bicalutamide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [bicalutamide binds to and results in decreased activity of AR protein] inhibits the reaction [Dehydroepiandrosterone results in decreased expression of CYP1A2 mRNA] and bicalutamide inhibits the reaction [Dehydroepiandrosterone results in increased degradation of CYP1A2 mRNA] CTD PMID:23603339 Cyp1a2 Rat bilirubin IXalpha decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Bilirubin results in decreased activity of CYP1A2 protein CTD PMID:16183037 Cyp1a2 Rat bilobalide multiple interactions EXP 6480464 bilobalide results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:18421621 Cyp1a2 Rat bilobalide increases expression EXP 6480464 bilobalide results in increased expression of CYP1A2 mRNA CTD PMID:18421621 Cyp1a2 Rat binimetinib multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [NADP co-treated with binimetinib] results in decreased activity of CYP1A2 protein CTD PMID:33728909 Cyp1a2 Rat biochanin A increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of biochanin A CTD PMID:12814970 Cyp1a2 Rat biochanin A decreases activity EXP 6480464 biochanin A results in decreased activity of CYP1A2 protein CTD PMID:26278343 Cyp1a2 Rat biochanin A decreases activity ISO CYP1A2 (Homo sapiens) 6480464 biochanin A results in decreased activity of CYP1A2 protein CTD PMID:26278343 Cyp1a2 Rat biphenyl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 biphenyl results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat biphenyl increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of biphenyl CTD PMID:27137136 Cyp1a2 Rat biphenyl-2-ol affects binding ISO CYP1A2 (Homo sapiens) 6480464 2-phenylphenol binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat biphenyl-4-amine increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased activity of 4-biphenylamine CTD PMID:15450435 Cyp1a2 Rat biphenyl-4-amine increases oxidation EXP 6480464 CYP1A2 protein results in increased oxidation of 4-biphenylamine CTD PMID:2908851 Cyp1a2 Rat biphenyl-4-amine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [furafylline results in decreased activity of CYP1A2 protein] which results in decreased susceptibility to 4-biphenylamine and CYP1A2 protein results in increased hydroxylation of and results in increased activity of 4-biphenylamine CTD PMID:16988941 and PMID:23898916 Cyp1a2 Rat biphenyl-4-amine increases metabolic processing ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased metabolism of 4-biphenylamine CTD PMID:11376689 Cyp1a2 Rat biphenyl-4-amine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 4-biphenylamine CTD PMID:2655891 Cyp1a2 Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 and PMID:36403809 Cyp1a2 Rat bis(2-ethylhexyl) phthalate increases expression ISO Cyp1a2 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of CYP1A2 protein CTD PMID:36403809 Cyp1a2 Rat bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of CYP1A2 mRNA CTD PMID:35970509 Cyp1a2 Rat bisphenol A increases glutathionylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased glutathionylation of bisphenol A and CYP1A2 protein results in increased glutathionylation of bisphenol A metabolite CTD PMID:23470418 Cyp1a2 Rat bisphenol A decreases activity ISO CYP1A2 (Homo sapiens) 6480464 bisphenol A results in decreased activity of CYP1A2 protein CTD PMID:33312107 Cyp1a2 Rat bisphenol A decreases expression ISO Cyp1a2 (Mus musculus) 6480464 bisphenol A results in decreased expression of CYP1A2 mRNA CTD PMID:29477810 Cyp1a2 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CYP1A2 mRNA CTD PMID:30903817 Cyp1a2 Rat bisphenol A increases expression ISO Cyp1a2 (Mus musculus) 6480464 bisphenol A results in increased expression of CYP1A2 mRNA CTD PMID:30790712 Cyp1a2 Rat bisphenol A multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Cesium-137 co-treated with bisphenol A] results in decreased expression of CYP1A2 mRNA more ... CTD PMID:28433925 and PMID:29477810 Cyp1a2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CYP1A2 mRNA CTD PMID:25181051 Cyp1a2 Rat bisphenol A increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of bisphenol A and CYP1A2 protein results in increased hydroxylation of bisphenol A metabolite CTD PMID:23470418 Cyp1a2 Rat bisphenol F increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of 4 and 4'-bisphenol F CTD PMID:23470418 Cyp1a2 Rat bisphenol F decreases activity ISO CYP1A2 (Homo sapiens) 6480464 bisphenol F results in decreased activity of CYP1A2 protein CTD PMID:33312107 Cyp1a2 Rat bisphenol F increases glutathionylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased glutathionylation of 4 and 4'-bisphenol F CTD PMID:23470418 Cyp1a2 Rat bortezomib affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Bortezomib CTD PMID:15764713 Cyp1a2 Rat bromfenac increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of bromfenac metabolite CTD PMID:31815452 Cyp1a2 Rat bromodichloromethane increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of bromodichloromethane CTD PMID:12076521 Cyp1a2 Rat bromodichloromethane increases metabolic processing EXP 6480464 CYP1A2 protein results in increased metabolism of bromodichloromethane CTD PMID:11295256 and PMID:12076521 Cyp1a2 Rat bromodichloromethane multiple interactions EXP 6480464 isosafrole inhibits the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane] and Tetrachlorodibenzodioxin promotes the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane] CTD PMID:12062927 Cyp1a2 Rat bromodichloromethane affects metabolic processing EXP 6480464 CYP1A2 protein affects the metabolism of bromodichloromethane CTD PMID:12062927 Cyp1a2 Rat bromodichloromethane increases expression EXP 6480464 bromodichloromethane results in increased expression of CYP1A2 protein CTD PMID:11295256 Cyp1a2 Rat bromodichloromethane decreases expression EXP 6480464 bromodichloromethane results in decreased expression of CYP1A2 protein CTD PMID:11295256 Cyp1a2 Rat bromuconazole increases expression EXP 6480464 bromuconazole results in increased expression of CYP1A2 mRNA CTD PMID:33789219 Cyp1a2 Rat brucine multiple interactions EXP 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein CTD PMID:21800547 Cyp1a2 Rat bucladesine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Bucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 Cyp1a2 Rat Bufuralol increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of bufuralol CTD PMID:9429232 Cyp1a2 Rat buta-1,3-diene decreases expression ISO Cyp1a2 (Mus musculus) 6480464 1 and 3-butadiene results in decreased expression of CYP1A2 mRNA CTD PMID:29038090 Cyp1a2 Rat butylated hydroxyanisole increases expression ISO Cyp1a2 (Mus musculus) 6480464 Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA CTD PMID:25174530 Cyp1a2 Rat butylated hydroxyanisole multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 CTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA] CTD PMID:25174530 Cyp1a2 Rat Butylbenzyl phthalate decreases activity EXP 6480464 butylbenzyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat Butylparaben decreases activity EXP 6480464 butylparaben results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat butyric acid increases expression ISO CYP1A2 (Homo sapiens) 6480464 Butyric Acid results in increased expression of CYP1A2 mRNA CTD PMID:30439556 Cyp1a2 Rat butyric acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Benzo(a)pyrene promotes the reaction [Butyric Acid results in increased expression of CYP1A2 mRNA] and Butyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:30439556 Cyp1a2 Rat C.I. Natural Red 20 decreases activity EXP 6480464 shikonin results in decreased activity of CYP1A2 protein CTD PMID:28941798 Cyp1a2 Rat C.I. Natural Red 20 decreases activity ISO CYP1A2 (Homo sapiens) 6480464 shikonin results in decreased activity of CYP1A2 protein CTD PMID:28941798 Cyp1a2 Rat C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of CYP1A2 mRNA CTD PMID:19167457 Cyp1a2 Rat cadmium dichloride decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased activity of CYP1A2 protein CTD PMID:11162773 Cyp1a2 Rat caffeine affects binding ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein binds to Caffeine CTD PMID:9334905 Cyp1a2 Rat caffeine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA CTD PMID:28843594 Cyp1a2 Rat caffeine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Caffeine CTD PMID:11907490 more ... Cyp1a2 Rat caffeine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein binds to and results in increased metabolism of Caffeine] which results in increased chemical synthesis of 1 more ... CTD PMID:11145498 more ... Cyp1a2 Rat caffeine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Caffeine results in decreased activity of CYP1A2 protein CTD PMID:11465391 and PMID:24211539 Cyp1a2 Rat caffeine decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Caffeine results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat caffeine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Caffeine and CYP1A2 protein affects the metabolism of Caffeine metabolite CTD PMID:1302044 more ... Cyp1a2 Rat caffeine multiple interactions EXP 6480464 [Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Caffeine more ... CTD PMID:12706856 more ... Cyp1a2 Rat caffeine affects metabolic processing EXP 6480464 CYP1A2 protein affects the metabolism of Caffeine CTD PMID:15619608 Cyp1a2 Rat caffeine increases activity EXP 6480464 Caffeine results in increased activity of CYP1A2 protein CTD PMID:15822860 Cyp1a2 Rat caffeine decreases methylation ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in decreased methylation of Caffeine CTD PMID:11376689 Cyp1a2 Rat caffeine decreases methylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of Caffeine CTD PMID:11145498 and PMID:12433797 Cyp1a2 Rat canadine increases expression ISO Cyp1a2 (Mus musculus) 6480464 canadine results in increased expression of CYP1A2 mRNA and canadine results in increased expression of CYP1A2 protein CTD PMID:28257954 Cyp1a2 Rat cannabidiol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Cannabidiol results in decreased activity of CYP1A2 protein CTD PMID:24667653 Cyp1a2 Rat cannabidiol increases expression ISO Cyp1a2 (Mus musculus) 6480464 Cannabidiol results in increased expression of CYP1A2 mRNA CTD PMID:31052254 Cyp1a2 Rat cannabidiol multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Plant Extracts results in increased abundance of Cannabidiol] which results in increased expression of CYP1A2 mRNA CTD PMID:33096940 Cyp1a2 Rat canthaxanthin increases expression EXP 6480464 Canthaxanthin results in increased expression of CYP1A2 mRNA CTD PMID:9271336 Cyp1a2 Rat canthaxanthin increases expression ISO Cyp1a2 (Mus musculus) 6480464 Canthaxanthin results in increased expression of CYP1A2 mRNA CTD PMID:9271336 Cyp1a2 Rat capsaicin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Capsaicin results in decreased activity of CYP1A2 protein CTD PMID:22375877 Cyp1a2 Rat carbamazepine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Carbamazepine results in increased expression of CYP1A2 mRNA CTD PMID:17112801 Cyp1a2 Rat carbamazepine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Carbamazepine CTD PMID:23397584 Cyp1a2 Rat carbamazepine decreases expression EXP 6480464 Carbamazepine results in decreased expression of CYP1A2 mRNA CTD PMID:17381134 Cyp1a2 Rat carbaryl multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Carbaryl inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol] and Carbaryl inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol] CTD PMID:16790556 Cyp1a2 Rat carbaryl increases expression EXP 6480464 Carbaryl results in increased expression of CYP1A2 protein CTD PMID:9858662 Cyp1a2 Rat carbaryl decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Carbaryl results in decreased activity of CYP1A2 protein CTD PMID:16790556 Cyp1a2 Rat carbendazim increases expression ISO CYP1A2 (Homo sapiens) 6480464 carbendazim results in increased expression of CYP1A2 mRNA and carbendazim results in increased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat carbofuran increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Carbofuran CTD PMID:15560889 Cyp1a2 Rat carbon nanotube decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 Cyp1a2 Rat Carnosol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 carnosol results in decreased activity of CYP1A2 protein CTD PMID:34592323 Cyp1a2 Rat carotenoid affects response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 Cyp1a2 Rat caryophyllene oxide decreases activity ISO CYP1A2 (Homo sapiens) 6480464 caryophyllene oxide results in decreased activity of CYP1A2 protein CTD PMID:29074051 Cyp1a2 Rat caryophyllene oxide decreases activity EXP 6480464 caryophyllene oxide results in decreased activity of CYP1A2 protein CTD PMID:29074051 Cyp1a2 Rat catechols multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased hydroxylation of zearalenol] which results in increased chemical synthesis of Catechols and [CYP1A2 protein results in increased hydroxylation of Zearalenone] which results in increased chemical synthesis of Catechols CTD PMID:19931366 Cyp1a2 Rat celecoxib decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Celecoxib results in decreased activity of CYP1A2 protein CTD PMID:18816299 Cyp1a2 Rat CGP 52608 multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to CYP1A2 gene] CTD PMID:28238834 Cyp1a2 Rat chalcone increases hydroxylation EXP 6480464 CYP1A2 protein results in increased hydroxylation of Chalcone CTD PMID:15863696 Cyp1a2 Rat chelidonine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of chelidonine CTD PMID:31102647 Cyp1a2 Rat chelidonine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of chelidonine] which results in increased abundance of Glutathione analog CTD PMID:31102647 Cyp1a2 Rat chenodeoxycholic acid decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Chenodeoxycholic Acid results in decreased expression of CYP1A2 mRNA CTD PMID:27174168 Cyp1a2 Rat chenodeoxycholic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of CYP1A2 mRNA more ... CTD PMID:33819548 Cyp1a2 Rat CHIR 99021 increases expression ISO CYP1A2 (Homo sapiens) 6480464 Chir 99021 results in increased expression of CYP1A2 mRNA CTD PMID:26259606 Cyp1a2 Rat CHIR 99021 multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Chir 99021 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:34403729 Cyp1a2 Rat chlorohydrocarbon multiple interactions EXP 6480464 [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CYP1A2 mRNA CTD PMID:30744511 Cyp1a2 Rat chloroquine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Chloroquine inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine] CTD PMID:7946932 Cyp1a2 Rat chlorotoluron decreases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased susceptibility to chlortoluron CTD PMID:24920432 Cyp1a2 Rat chlorpromazine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA more ... CTD PMID:18493746 more ... Cyp1a2 Rat chlorpromazine decreases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 Cyp1a2 Rat chlorpromazine increases expression EXP 6480464 Chlorpromazine results in increased expression of CYP1A2 mRNA CTD PMID:25596134 Cyp1a2 Rat chlorpromazine increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of Chlorpromazine CTD PMID:20615392 Cyp1a2 Rat chlorpromazine affects expression EXP 6480464 Chlorpromazine affects the expression of CYP1A2 mRNA CTD PMID:18246545 Cyp1a2 Rat chlorpromazine decreases methylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of Chlorpromazine CTD PMID:20615392 Cyp1a2 Rat chlorpyrifos multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Chlorpyrifos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol] and Chlorpyrifos inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol] CTD PMID:16790556 Cyp1a2 Rat chlorpyrifos increases expression ISO Cyp1a2 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of CYP1A2 mRNA CTD PMID:29097212 Cyp1a2 Rat chlorpyrifos multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Dietary Fats results in increased susceptibility to Chlorpyrifos] which results in decreased expression of CYP1A2 mRNA and Chlorpyrifos inhibits the reaction [Dietary Fats results in decreased expression of CYP1A2 mRNA] CTD PMID:29097212 and PMID:29935250 Cyp1a2 Rat chlorpyrifos decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Chlorpyrifos results in decreased activity of CYP1A2 protein CTD PMID:16790556 more ... Cyp1a2 Rat chlorpyrifos increases expression ISO CYP1A2 (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of CYP1A2 mRNA CTD PMID:16190164 more ... Cyp1a2 Rat chlorpyrifos affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Chlorpyrifos CTD PMID:15557345 and PMID:17079358 Cyp1a2 Rat chlorpyrifos decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Chlorpyrifos results in decreased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat chlorzoxazone affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Chlorzoxazone CTD PMID:14586387 Cyp1a2 Rat chlorzoxazone affects metabolic processing EXP 6480464 CYP1A2 protein affects the metabolism of Chlorzoxazone CTD PMID:15879494 Cyp1a2 Rat chlorzoxazone increases hydroxylation EXP 6480464 CYP1A2 protein results in increased hydroxylation of Chlorzoxazone CTD PMID:11911841 Cyp1a2 Rat choline multiple interactions EXP 6480464 [Choline deficiency co-treated with Methionine deficiency] results in decreased activity of CYP1A2 protein more ... CTD PMID:18798224 and PMID:38663832 Cyp1a2 Rat choline multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [3 more ... CTD PMID:27712037 more ... Cyp1a2 Rat chromium(6+) increases expression ISO CYP1A2 (Homo sapiens) 6480464 chromium hexavalent ion results in increased expression of CYP1A2 protein CTD PMID:36368423 Cyp1a2 Rat chromium(6+) multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [chromium hexavalent ion results in increased expression of CYP1A2 protein] and AHR protein affects the reaction [chromium hexavalent ion results in increased expression of CYP1A2 protein] CTD PMID:36368423 Cyp1a2 Rat chrysazin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 danthron results in decreased activity of CYP1A2 protein CTD PMID:33438235 Cyp1a2 Rat chrysene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of chrysene and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene] CTD PMID:8961944 Cyp1a2 Rat chrysene multiple interactions EXP 6480464 [chrysene co-treated with Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1A2 mRNA more ... CTD PMID:37189300 Cyp1a2 Rat chrysene increases expression ISO CYP1A2 (Homo sapiens) 6480464 chrysene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 more ... Cyp1a2 Rat chrysene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of chrysene more ... CTD PMID:7750161 and PMID:8961944 Cyp1a2 Rat chrysin increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of chrysin CTD PMID:19666078 Cyp1a2 Rat chrysin increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of chrysin CTD PMID:30964977 Cyp1a2 Rat chrysin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein CTD PMID:19666078 Cyp1a2 Rat chrysin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 chrysin results in decreased activity of CYP1A2 protein CTD PMID:20806393 and PMID:21053930 Cyp1a2 Rat chrysophanol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 chrysophanic acid results in decreased activity of CYP1A2 protein CTD PMID:27633141 and PMID:33438235 Cyp1a2 Rat chrysophanol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of chrysophanic acid] which results in increased chemical synthesis of 2-hydroxychrysophanol CTD PMID:29698620 Cyp1a2 Rat chrysophanol increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of chrysophanic acid CTD PMID:29698620 Cyp1a2 Rat ciglitazone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of CYP1A2 mRNA and [ciglitazone binds to PPARG protein] which results in increased expression of CYP1A2 mRNA CTD PMID:16197558 Cyp1a2 Rat cimetidine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Cimetidine results in decreased activity of CYP1A2 protein CTD PMID:19909766 and PMID:31863871 Cyp1a2 Rat cimetidine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Cimetidine inhibits the reaction [CYP1A2 protein results in increased metabolism of Tacrine] more ... CTD PMID:19909766 and PMID:7946932 Cyp1a2 Rat ciprofibrate decreases expression EXP 6480464 ciprofibrate results in decreased expression of CYP1A2 mRNA CTD PMID:7676460 Cyp1a2 Rat ciprofibrate decreases expression ISO Cyp1a2 (Mus musculus) 6480464 ciprofibrate results in decreased expression of CYP1A2 mRNA CTD PMID:17962186 Cyp1a2 Rat ciprofibrate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 ciprofibrate inhibits the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA] CTD PMID:17962186 Cyp1a2 Rat ciprofloxacin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine more ... CTD PMID:11145498 more ... Cyp1a2 Rat ciprofloxacin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Ciprofloxacin results in decreased activity of CYP1A2 protein CTD PMID:11145498 more ... Cyp1a2 Rat cisplatin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Cisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat cisplatin increases expression ISO CYP1A2 (Homo sapiens) 6480464 Cisplatin results in increased expression of CYP1A2 mRNA CTD PMID:38498338 Cyp1a2 Rat cisplatin multiple interactions EXP 6480464 Cisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat clarithromycin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline] CTD PMID:11408986 Cyp1a2 Rat clenbuterol multiple interactions EXP 6480464 Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein] and Propranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]] CTD PMID:15710352 Cyp1a2 Rat clodronic acid increases expression ISO CYP1A2 (Homo sapiens) 6480464 Clodronic Acid results in increased expression of CYP1A2 mRNA CTD PMID:25596134 Cyp1a2 Rat clofibrate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CYP1A2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP1A2 mRNA] CTD PMID:17585979 Cyp1a2 Rat clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of CYP1A2 mRNA and Clofibrate results in decreased expression of CYP1A2 protein CTD PMID:11328961 more ... Cyp1a2 Rat clofibrate decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Clofibrate results in decreased expression of CYP1A2 mRNA CTD PMID:17585979 Cyp1a2 Rat clofibric acid affects expression EXP 6480464 Clofibric Acid affects the expression of CYP1A2 mRNA CTD PMID:17602206 Cyp1a2 Rat clopidogrel multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of and results in increased cleavage of Clopidogrel metabolite and furafylline inhibits the reaction [CYP1A2 protein results in increased oxidation of Clopidogrel] CTD PMID:19170597 and PMID:19812348 Cyp1a2 Rat clopidogrel increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of clopidogrel CTD PMID:19812348 Cyp1a2 Rat clothianidin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA and [enilconazole co-treated with thiacloprid co-treated with clothianidin] results in increased expression of CYP1A2 mRNA CTD PMID:32201337 Cyp1a2 Rat clothianidin increases expression ISO CYP1A2 (Homo sapiens) 6480464 clothianidin results in increased expression of CYP1A2 mRNA CTD PMID:32201337 Cyp1a2 Rat clotrimazole increases expression EXP 6480464 Clotrimazole results in increased expression of CYP1A2 protein CTD PMID:7986207 Cyp1a2 Rat clotrimazole multiple interactions EXP 6480464 Clotrimazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin] CTD PMID:19858067 Cyp1a2 Rat clozapine affects response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene SNP affects the susceptibility to Clozapine and CYP1A2 protein affects the susceptibility to Clozapine CTD PMID:12919186 and PMID:15206669 Cyp1a2 Rat clozapine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene SNP results in increased metabolism of Clozapine and CYP1A2 protein results in increased metabolism of Clozapine CTD PMID:11763009 more ... Cyp1a2 Rat clozapine decreases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene SNP results in decreased metabolism of Clozapine CTD PMID:12919186 Cyp1a2 Rat clozapine decreases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene SNP results in decreased susceptibility to Clozapine CTD PMID:11763009 Cyp1a2 Rat clozapine multiple interactions EXP 6480464 Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat clozapine increases metabolic processing ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased metabolism of Clozapine CTD PMID:12969762 Cyp1a2 Rat clozapine increases expression ISO Cyp1a2 (Mus musculus) 6480464 Clozapine results in increased expression of CYP1A2 mRNA CTD PMID:12969762 Cyp1a2 Rat clozapine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene polymorphism affects the metabolism of Clozapine more ... CTD PMID:15286053 more ... Cyp1a2 Rat clozapine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine more ... CTD PMID:11151749 more ... Cyp1a2 Rat Clozapine N-oxide increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of clozapine N-oxide CTD PMID:27320963 Cyp1a2 Rat Clozapine N-oxide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Fluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of clozapine N-oxide] CTD PMID:18809730 Cyp1a2 Rat Clozapine N-oxide increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of clozapine N-oxide CTD PMID:18809730 Cyp1a2 Rat cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of CYP1A2 mRNA CTD PMID:24386269 Cyp1a2 Rat colforsin daropate hydrochloride multiple interactions EXP 6480464 Colforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein] CTD PMID:15710352 Cyp1a2 Rat colforsin daropate hydrochloride multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Colforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 Cyp1a2 Rat copper atom multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 Cyp1a2 Rat copper(0) multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 Cyp1a2 Rat copper(II) sulfate decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of CYP1A2 mRNA CTD PMID:19549813 Cyp1a2 Rat corticosterone multiple interactions EXP 6480464 Corticosterone promotes the reaction [Ethanol results in increased expression of CYP1A2 mRNA] CTD PMID:35301062 Cyp1a2 Rat corticosterone increases expression ISO CYP1A2 (Homo sapiens) 6480464 Corticosterone results in increased expression of CYP1A2 mRNA CTD PMID:35301062 Cyp1a2 Rat corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of CYP1A2 mRNA CTD PMID:35301062 Cyp1a2 Rat coumarin decreases expression EXP 6480464 coumarin results in decreased expression of CYP1A2 mRNA CTD PMID:18480146 Cyp1a2 Rat coumarin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of coumarin] which results in increased abundance of 2-hydroxyphenylacetic acid and [CYP1A2 protein results in increased metabolism of coumarin] which results in increased abundance of 7-hydroxycoumarin CTD PMID:34334558 Cyp1a2 Rat coumarin increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of coumarin CTD PMID:34334558 Cyp1a2 Rat coumarin affects expression EXP 6480464 coumarin affects the expression of CYP1A2 mRNA CTD PMID:16963487 Cyp1a2 Rat Cryptotanshinone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 cryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] more ... CTD PMID:21262253 Cyp1a2 Rat Cryptotanshinone increases expression ISO CYP1A2 (Homo sapiens) 6480464 cryptotanshinone results in increased expression of CYP1A2 mRNA and cryptotanshinone results in increased expression of CYP1A2 protein CTD PMID:21262253 Cyp1a2 Rat curcumin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Curcumin results in decreased activity of CYP1A2 protein CTD PMID:15841493 Cyp1a2 Rat curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A2 protein] and Curcumin inhibits the reaction [Fenitrothion results in increased expression of CYP1A2 mRNA] CTD PMID:16288784 and PMID:34802538 Cyp1a2 Rat curcumin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of CYP1A2 mRNA] more ... CTD PMID:18321868 and PMID:35063475 Cyp1a2 Rat cyclobarbital increases expression ISO Cyp1a2 (Mus musculus) 6480464 cyclobarbital results in increased expression of CYP1A2 mRNA CTD PMID:10064569 Cyp1a2 Rat cycloheximide multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Cycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 Cyp1a2 Rat cyclophosphamide decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Cyclophosphamide results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of CYP1A2 mRNA CTD PMID:25596134 Cyp1a2 Rat cyclosporin A multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Cyclosporine] results in decreased expression of CYP1A2 mRNA CTD PMID:33819548 Cyp1a2 Rat cyhalothrin increases activity ISO CYP1A2 (Homo sapiens) 6480464 cyhalothrin results in increased activity of CYP1A2 protein CTD PMID:22310298 Cyp1a2 Rat cyhalothrin increases activity EXP 6480464 cyhalothrin results in increased activity of CYP1A2 protein CTD PMID:29727961 Cyp1a2 Rat cyhalothrin increases expression EXP 6480464 cyhalothrin results in increased expression of CYP1A2 mRNA CTD PMID:29727961 Cyp1a2 Rat cylindrospermopsin increases expression ISO CYP1A2 (Homo sapiens) 6480464 cylindrospermopsin results in increased expression of CYP1A2 mRNA CTD PMID:21607682 Cyp1a2 Rat cylindrospermopsin decreases expression ISO Cyp1a2 (Mus musculus) 6480464 cylindrospermopsin results in decreased expression of CYP1A2 mRNA CTD PMID:20936652 Cyp1a2 Rat cypermethrin decreases activity ISO Cyp1a2 (Mus musculus) 6480464 cypermethrin results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of CYP1A2 mRNA CTD PMID:23447098 and PMID:26115703 Cyp1a2 Rat cyproconazole increases expression ISO Cyp1a2 (Mus musculus) 6480464 cyproconazole results in increased expression of CYP1A2 mRNA CTD PMID:22334560 and PMID:25656644 Cyp1a2 Rat cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of CYP1A2 protein CTD PMID:33150952 Cyp1a2 Rat cyproconazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 cyproconazole results in increased expression of CYP1A2 mRNA and cyproconazole results in increased expression of CYP1A2 protein CTD PMID:29995386 and PMID:33150952 Cyp1a2 Rat cyproconazole multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 NR1I3 promotes the reaction [cyproconazole results in increased expression of CYP1A2 mRNA] CTD PMID:25656644 Cyp1a2 Rat D-glucose multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31776611 Cyp1a2 Rat dabrafenib decreases activity ISO CYP1A2 (Homo sapiens) 6480464 dabrafenib results in decreased activity of CYP1A2 protein CTD PMID:34780725 Cyp1a2 Rat dacarbazine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Dacarbazine metabolite CTD PMID:11751525 Cyp1a2 Rat dacarbazine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 O(6)-benzylguanine inhibits the reaction [CYP1A2 protein results in increased metabolism of Dacarbazine metabolite] CTD PMID:11751525 Cyp1a2 Rat daidzein decreases activity ISO Cyp1a2 (Mus musculus) 6480464 daidzein results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat dantrolene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat DDT increases expression EXP 6480464 DDT results in increased expression of CYP1A2 mRNA CTD PMID:29477483 Cyp1a2 Rat decabromodiphenyl ether increases activity EXP 6480464 decabromobiphenyl ether results in increased activity of CYP1A2 protein CTD PMID:18495385 Cyp1a2 Rat decabromodiphenyl ether increases expression ISO CYP1A2 (Homo sapiens) 6480464 decabromobiphenyl ether results in increased expression of CYP1A2 mRNA CTD PMID:19270788 Cyp1a2 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of CYP1A2 mRNA and decabromobiphenyl ether results in increased expression of CYP1A2 protein CTD PMID:18495385 more ... Cyp1a2 Rat dehydroepiandrosterone decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Dehydroepiandrosterone results in decreased expression of CYP1A2 mRNA CTD PMID:23603339 Cyp1a2 Rat dehydroepiandrosterone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [bicalutamide binds to and results in decreased activity of AR protein] inhibits the reaction [Dehydroepiandrosterone results in decreased expression of CYP1A2 mRNA] more ... CTD PMID:23603339 Cyp1a2 Rat dehydroepiandrosterone increases degradation ISO CYP1A2 (Homo sapiens) 6480464 Dehydroepiandrosterone results in increased degradation of CYP1A2 mRNA CTD PMID:23603339 Cyp1a2 Rat deoxycholic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of CYP1A2 mRNA more ... CTD PMID:33819548 Cyp1a2 Rat Deoxyschizandrin decreases activity ISO Cyp1a2 (Mus musculus) 6480464 schizandrin A results in decreased activity of CYP1A2 protein CTD PMID:25753323 Cyp1a2 Rat desogestrel decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Desogestrel results in decreased activity of CYP1A2 protein CTD PMID:18816299 Cyp1a2 Rat dexamethasone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein] more ... CTD PMID:19022236 Cyp1a2 Rat dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of CYP1A2 mRNA CTD PMID:11328961 more ... Cyp1a2 Rat dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of CYP1A2 mRNA CTD PMID:15607757 Cyp1a2 Rat dexamethasone multiple interactions EXP 6480464 Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] and Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]] CTD PMID:17690134 Cyp1a2 Rat dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of CYP1A2 mRNA CTD PMID:15102944 Cyp1a2 Rat dexamethasone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Dexamethasone results in decreased activity of CYP1A2 protein CTD PMID:19022236 Cyp1a2 Rat dexamethasone decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Dexamethasone results in decreased expression of CYP1A2 protein CTD PMID:19022236 Cyp1a2 Rat dexmedetomidine multiple interactions EXP 6480464 atipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]] more ... CTD PMID:16510159 Cyp1a2 Rat dextran sulfate multiple interactions EXP 6480464 [Dextran Sulfate results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of Acetaminophen CTD PMID:28438436 Cyp1a2 Rat dextran sulfate decreases activity EXP 6480464 Dextran Sulfate results in decreased activity of CYP1A2 protein CTD PMID:28438436 Cyp1a2 Rat dextromethorphan affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Dextromethorphan CTD PMID:15199075 Cyp1a2 Rat diallyl disulfide increases expression EXP 6480464 diallyl disulfide results in increased expression of CYP1A2 protein CTD PMID:16000231 Cyp1a2 Rat Diallyl sulfide multiple interactions EXP 6480464 allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP1A2 protein] and allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP1A2 mRNA] CTD PMID:23494807 Cyp1a2 Rat Diallyl sulfide increases expression EXP 6480464 allyl sulfide results in increased expression of CYP1A2 mRNA CTD PMID:19695238 and PMID:8849338 Cyp1a2 Rat diallyl trisulfide multiple interactions EXP 6480464 diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein] CTD PMID:28115069 Cyp1a2 Rat diarsenic trioxide multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] and Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein] CTD PMID:35872050 Cyp1a2 Rat diarsenic trioxide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] and Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:35872050 Cyp1a2 Rat diarylheptanoid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Diarylheptanoids results in decreased activity of CYP1A2 protein CTD PMID:23850985 Cyp1a2 Rat diazinon multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased sulfation of and results in increased activity of Diazinon and CYP1A2 protein results in increased metabolism of and results in increased activity of Diazinon CTD PMID:11708902 and PMID:15764407 Cyp1a2 Rat diazinon affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Diazinon CTD PMID:15557345 and PMID:15764407 Cyp1a2 Rat diazinon multiple interactions EXP 6480464 [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon CTD PMID:17442507 Cyp1a2 Rat diazinon increases expression ISO CYP1A2 (Homo sapiens) 6480464 Diazinon results in increased expression of CYP1A2 mRNA and Diazinon results in increased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat Dibenz[a,c]anthracene increases expression ISO CYP1A2 (Homo sapiens) 6480464 benzotriphenylene results in increased expression of CYP1A2 mRNA CTD PMID:17253728 Cyp1a2 Rat dibenz[a,h]anthracene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 more ... Cyp1a2 Rat dibenz[a,h]anthracene multiple interactions EXP 6480464 [1 more ... CTD PMID:18711122 Cyp1a2 Rat dibenz[a,h]anthracene increases expression ISO CYP1A2 (Homo sapiens) 6480464 1 more ... CTD PMID:16269432 and PMID:17253728 Cyp1a2 Rat dibenz[a,h]anthracene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 1 more ... CTD PMID:11162773 Cyp1a2 Rat dibenz[a,h]anthracene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 1 more ... CTD PMID:8961944 Cyp1a2 Rat dibenz[a,h]anthracene increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of 1 more ... CTD PMID:8638931 Cyp1a2 Rat dibenz[a,h]anthracene increases activity ISO CYP1A2 (Homo sapiens) 6480464 1 more ... CTD PMID:19362136 Cyp1a2 Rat dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A2 protein] CTD PMID:26880746 Cyp1a2 Rat dibenziodolium decreases activity EXP 6480464 diphenyleneiodonium results in decreased activity of CYP1A2 protein CTD PMID:26880746 Cyp1a2 Rat dibenzo[a,l]pyrene increases activity ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased activity of dibenzo(a and l)pyrene CTD PMID:15606143 Cyp1a2 Rat dibenzo[a,l]pyrene multiple interactions EXP 6480464 [1 more ... CTD PMID:18711122 Cyp1a2 Rat dibenzo[a,l]pyrene increases expression ISO CYP1A2 (Homo sapiens) 6480464 dibenzo(a and l)pyrene results in increased expression of CYP1A2 mRNA CTD PMID:16269432 Cyp1a2 Rat dibenzo[a,l]pyrene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with dibenzo(a and l)pyrene] affects the expression of CYP1A2 mRNA CTD PMID:17690111 Cyp1a2 Rat dibenzofuran increases activity ISO Cyp1a2 (Mus musculus) 6480464 dibenzofuran results in increased activity of CYP1A2 protein CTD PMID:8001243 Cyp1a2 Rat dibenzofuran multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat dibenzofuran increases activity ISO CYP1A2 (Homo sapiens) 6480464 dibenzofuran metabolite results in increased activity of CYP1A2 protein CTD PMID:26032510 Cyp1a2 Rat dibenzofurans increases expression ISO Cyp1a2 (Mus musculus) 6480464 Dibenzofurans results in increased expression of CYP1A2 mRNA CTD PMID:34254344 Cyp1a2 Rat dibutyl phthalate decreases activity EXP 6480464 Dibutyl Phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat dichloroacetic acid decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Dichloroacetic Acid results in decreased expression of CYP1A2 mRNA CTD PMID:28962523 Cyp1a2 Rat dichloromethane affects expression ISO Cyp1a2 (Mus musculus) 6480464 Methylene Chloride affects the expression of CYP1A2 mRNA CTD PMID:28392392 Cyp1a2 Rat diclofenac increases expression ISO CYP1A2 (Homo sapiens) 6480464 Diclofenac results in increased expression of CYP1A2 mRNA and Diclofenac results in increased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat diclofenac decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Diclofenac metabolite results in decreased activity of CYP1A2 protein CTD PMID:28960974 Cyp1a2 Rat diclofenac multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac CTD PMID:23397584 Cyp1a2 Rat dicofol increases expression EXP 6480464 Dicofol results in increased expression of CYP1A2 mRNA CTD PMID:19595748 Cyp1a2 Rat dicrotophos increases expression ISO CYP1A2 (Homo sapiens) 6480464 dicrotophos results in increased expression of CYP1A2 mRNA CTD PMID:28302478 Cyp1a2 Rat Dicyclohexyl phthalate decreases activity EXP 6480464 dicyclohexyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of CYP1A2 mRNA CTD PMID:10910964 Cyp1a2 Rat diethyl phthalate decreases activity EXP 6480464 diethyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat diethyldithiocarbamic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Ditiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat diethyldithiocarbamic acid multiple interactions EXP 6480464 Ditiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat diethylstilbestrol affects response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the susceptibility to Diethylstilbestrol CTD PMID:8242868 Cyp1a2 Rat difenoconazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 difenoconazole results in increased expression of CYP1A2 mRNA CTD PMID:33575850 Cyp1a2 Rat difenoconazole increases expression ISO Cyp1a2 (Mus musculus) 6480464 difenoconazole results in increased expression of CYP1A2 mRNA CTD PMID:34425431 Cyp1a2 Rat difenoconazole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [difenoconazole co-treated with fludioxonil] results in increased expression of CYP1A2 mRNA CTD PMID:33575850 Cyp1a2 Rat diflubenzuron affects binding ISO CYP1A2 (Homo sapiens) 6480464 Diflubenzuron binds to CYP1A2 protein CTD PMID:32278787 Cyp1a2 Rat dihydroartemisinin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 artenimol results in decreased activity of CYP1A2 protein CTD PMID:11124226 Cyp1a2 Rat dihydrocapsaicin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 dihydrocapsaicin results in decreased activity of CYP1A2 protein CTD PMID:22375877 Cyp1a2 Rat Dihydrotanshinone I multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [dihydrotanshinone I results in increased expression of CYP1A2 mRNA] more ... CTD PMID:21262253 Cyp1a2 Rat Dihydrotanshinone I increases expression ISO CYP1A2 (Homo sapiens) 6480464 dihydrotanshinone I results in increased expression of CYP1A2 mRNA and dihydrotanshinone I results in increased expression of CYP1A2 protein CTD PMID:21262253 Cyp1a2 Rat dimethocaine increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of dimethocaine CTD PMID:24309420 Cyp1a2 Rat Dimethyl phthalate decreases activity EXP 6480464 dimethyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat dimethyl sulfoxide affects expression ISO CYP1A2 (Homo sapiens) 6480464 Dimethyl Sulfoxide affects the expression of CYP1A2 mRNA CTD PMID:12843640 Cyp1a2 Rat dimethyl sulfoxide increases expression ISO CYP1A2 (Homo sapiens) 6480464 Dimethyl Sulfoxide results in increased expression of CYP1A2 mRNA CTD PMID:30262279 Cyp1a2 Rat dimethyl sulfoxide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Dimethyl Sulfoxide co-treated with TGFB1 protein] results in decreased expression of CYP1A2 mRNA more ... CTD PMID:18347083 and PMID:35366062 Cyp1a2 Rat dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of CYP1A2 mRNA CTD PMID:17481689 Cyp1a2 Rat dimethylmercury decreases expression EXP 6480464 dimethyl mercury results in decreased expression of CYP1A2 protein CTD PMID:21424224 Cyp1a2 Rat dimethylmercury multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein] CTD PMID:21424224 Cyp1a2 Rat diosmetin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 diosmetin results in decreased activity of CYP1A2 protein CTD PMID:28867436 Cyp1a2 Rat diosmetin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased susceptibility to Luteolin] which results in decreased abundance of diosmetin CTD PMID:33727136 Cyp1a2 Rat diosmetin increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to diosmetin CTD PMID:33727136 Cyp1a2 Rat dioxygen decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of CYP1A2 mRNA CTD PMID:19695866 Cyp1a2 Rat dioxygen increases activity EXP 6480464 Oxygen results in increased activity of CYP1A2 protein CTD PMID:10640292 Cyp1a2 Rat dioxygen increases expression ISO CYP1A2 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of CYP1A2 mRNA CTD PMID:33811995 Cyp1a2 Rat dioxygen increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 gene mutant form results in increased susceptibility to Oxygen CTD PMID:29180065 Cyp1a2 Rat dioxygen increases expression ISO Cyp1a2 (Mus musculus) 6480464 Oxygen results in increased expression of CYP1A2 mRNA CTD PMID:25703676 Cyp1a2 Rat dioxygen multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 gene mutant form results in increased susceptibility to Oxygen] which results in increased expression of NQO1 mRNA more ... CTD PMID:26845733 more ... Cyp1a2 Rat dioxygen multiple interactions EXP 6480464 [1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A2 protein more ... CTD PMID:10640292 more ... Cyp1a2 Rat dioxygen increases activity ISO Cyp1a2 (Mus musculus) 6480464 Oxygen results in increased activity of CYP1A2 protein CTD PMID:21745492 Cyp1a2 Rat dioxygen multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen] more ... CTD PMID:21745492 more ... Cyp1a2 Rat dipropyl phthalate decreases activity EXP 6480464 di-n-propylphthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat diuron increases expression ISO CYP1A2 (Homo sapiens) 6480464 Diuron results in increased expression of CYP1A2 mRNA and Diuron results in increased expression of CYP1A2 protein CTD PMID:21784029 and PMID:22310298 Cyp1a2 Rat domperidone increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Domperidone CTD PMID:15327587 Cyp1a2 Rat dopamine decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Dopamine results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat doxorubicin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Doxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat doxorubicin multiple interactions EXP 6480464 Doxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat elemental selenium multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein] CTD PMID:21424224 Cyp1a2 Rat Elemicin increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of elemicin CTD PMID:31468958 Cyp1a2 Rat Elemicin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of elemicin] which results in increased abundance of elemicin metabolite CTD PMID:31468958 Cyp1a2 Rat ellipticine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of ellipticine CTD PMID:22917556 Cyp1a2 Rat ellipticine multiple interactions EXP 6480464 ellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat ellipticine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 ellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat emodin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite CTD PMID:27989148 Cyp1a2 Rat emodin increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Emodin CTD PMID:30672276 Cyp1a2 Rat emodin increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of Emodin CTD PMID:27989148 Cyp1a2 Rat emodin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Emodin results in decreased activity of CYP1A2 protein CTD PMID:27633141 and PMID:33438235 Cyp1a2 Rat endosulfan increases expression ISO Cyp1a2 (Mus musculus) 6480464 Endosulfan analog results in increased expression of CYP1A2 mRNA and Endosulfan results in increased expression of CYP1A2 mRNA CTD PMID:29702342 Cyp1a2 Rat enfuvirtide affects activity ISO CYP1A2 (Homo sapiens) 6480464 enfuvirtide affects the activity of CYP1A2 protein CTD PMID:15656696 Cyp1a2 Rat enilconazole affects expression ISO CYP1A2 (Homo sapiens) 6480464 enilconazole affects the expression of CYP1A2 mRNA CTD PMID:32201337 Cyp1a2 Rat enilconazole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [clothianidin co-treated with enilconazole] results in increased expression of CYP1A2 mRNA more ... CTD PMID:32201337 Cyp1a2 Rat enoxacin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Enoxacin inhibits the reaction [CYP1A2 protein affects the metabolism of Fluvoxamine] more ... CTD PMID:15905806 and PMID:7946932 Cyp1a2 Rat enoxacin multiple interactions EXP 6480464 Enoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin] CTD PMID:8905919 Cyp1a2 Rat enoxacin affects binding EXP 6480464 Enoxacin binds to CYP1A2 protein CTD PMID:8905919 Cyp1a2 Rat enoxacin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Enoxacin results in decreased activity of CYP1A2 protein CTD PMID:15905806 Cyp1a2 Rat epoxiconazole increases expression ISO Cyp1a2 (Mus musculus) 6480464 epoxiconazole results in increased expression of CYP1A2 mRNA CTD PMID:22334560 Cyp1a2 Rat Erucin increases expression EXP 6480464 erucin results in increased expression of CYP1A2 protein CTD PMID:20833222 Cyp1a2 Rat estragole increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of estragole CTD PMID:19920071 Cyp1a2 Rat estragole increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to estragole CTD PMID:32853702 Cyp1a2 Rat estragole multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [flumequine co-treated with estragole] results in increased expression of CYP1A2 mRNA CTD PMID:31029721 Cyp1a2 Rat estragole increases expression ISO Cyp1a2 (Mus musculus) 6480464 estragole results in increased expression of CYP1A2 mRNA CTD PMID:31029721 Cyp1a2 Rat estrone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine] CTD PMID:21907773 Cyp1a2 Rat estrone affects binding ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein binds to Estrone CTD PMID:27966929 Cyp1a2 Rat ethambutol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Ethambutol results in decreased activity of CYP1A2 protein CTD PMID:24910189 Cyp1a2 Rat ethanol increases expression ISO CYP1A2 (Homo sapiens) 401976472 ethanol increases expression of CYP1A2 mRNA and protein in cervical cancer cells RGD Cyp1a2 Rat ethanol increases expression ISO CYP1A2 (Homo sapiens) 6480464 Ethanol results in increased expression of CYP1A2 mRNA CTD PMID:35301062 Cyp1a2 Rat ethanol multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of CYP1A2 mRNA CTD PMID:30517762 Cyp1a2 Rat ethanol multiple interactions EXP 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in decreased expression of CYP1A2 protein more ... CTD PMID:26747958 and PMID:35301062 Cyp1a2 Rat ethanol increases expression EXP 6480464 Ethanol results in increased expression of CYP1A2 mRNA and Ethanol results in increased expression of CYP1A2 protein CTD PMID:23273579 more ... Cyp1a2 Rat ethoxyquin increases expression EXP 6480464 Ethoxyquin results in increased expression of CYP1A2 mRNA CTD PMID:19695238 Cyp1a2 Rat ethylisopropylamiloride decreases activity ISO CYP1A2 (Homo sapiens) 6480464 ethylisopropylamiloride results in decreased activity of CYP1A2 protein CTD PMID:15081870 Cyp1a2 Rat ethylparaben decreases activity EXP 6480464 ethyl-p-hydroxybenzoate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat etodolac decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Etodolac results in decreased activity of CYP1A2 protein CTD PMID:18816299 Cyp1a2 Rat etoposide increases expression ISO CYP1A2 (Homo sapiens) 6480464 Etoposide results in increased expression of CYP1A2 mRNA CTD PMID:31542801 Cyp1a2 Rat etoricoxib decreases activity ISO CYP1A2 (Homo sapiens) 6480464 etoricoxib results in decreased activity of CYP1A2 protein CTD PMID:18816299 Cyp1a2 Rat eugenol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol CTD PMID:15576237 Cyp1a2 Rat farnesol increases activity EXP 6480464 Farnesol results in increased activity of CYP1A2 protein CTD PMID:15840382 Cyp1a2 Rat farnesol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA] CTD PMID:30611723 Cyp1a2 Rat farrerol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 farrerol results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat felbamate decreases expression EXP 6480464 felbamate results in decreased expression of CYP1A2 mRNA CTD PMID:17381134 Cyp1a2 Rat felodipine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Felodipine results in increased expression of CYP1A2 mRNA CTD PMID:27732883 Cyp1a2 Rat fenarimol multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [fenarimol co-treated with acephate] affects the expression of CYP1A2 protein more ... CTD PMID:17686559 Cyp1a2 Rat fenbendazole decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Fenbendazole results in decreased activity of CYP1A2 protein CTD PMID:22048645 Cyp1a2 Rat fenitrothion increases expression ISO CYP1A2 (Homo sapiens) 6480464 Fenitrothion results in increased expression of CYP1A2 mRNA CTD PMID:22310298 Cyp1a2 Rat fenitrothion increases expression EXP 6480464 Fenitrothion results in increased expression of CYP1A2 mRNA CTD PMID:34802538 Cyp1a2 Rat fenitrothion multiple interactions EXP 6480464 Curcumin inhibits the reaction [Fenitrothion results in increased expression of CYP1A2 mRNA] CTD PMID:34802538 Cyp1a2 Rat fenitrothion decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Fenitrothion results in decreased activity of CYP1A2 protein CTD PMID:20183062 and PMID:22634058 Cyp1a2 Rat fenofibrate multiple interactions EXP 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA CTD PMID:18253720 Cyp1a2 Rat fenofibrate affects expression EXP 6480464 Fenofibrate affects the expression of CYP1A2 mRNA CTD PMID:20801182 and PMID:25596134 Cyp1a2 Rat fenproporex decreases alkylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased alkylation of fenproporex CTD PMID:15294457 Cyp1a2 Rat fenvalerate increases activity ISO CYP1A2 (Homo sapiens) 6480464 fenvalerate results in increased activity of CYP1A2 protein CTD PMID:22310298 Cyp1a2 Rat ferulic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 ferulic acid results in decreased activity of CYP1A2 protein CTD PMID:15841493 Cyp1a2 Rat finasteride decreases expression EXP 6480464 Finasteride results in decreased expression of CYP1A2 mRNA CTD PMID:24136188 Cyp1a2 Rat fipronil multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [fipronil co-treated with DEET] results in increased expression of CYP1A2 mRNA CTD PMID:27091632 Cyp1a2 Rat flavanone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 flavanone results in decreased activity of CYP1A2 protein CTD PMID:21053930 Cyp1a2 Rat flavone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 flavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:17090139 Cyp1a2 Rat flavone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 flavone results in decreased activity of CYP1A2 protein CTD PMID:21053930 Cyp1a2 Rat flavonol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 3-hydroxyflavone results in decreased activity of CYP1A2 protein CTD PMID:21053930 and PMID:29753067 Cyp1a2 Rat fluconazole increases expression ISO Cyp1a2 (Mus musculus) 6480464 Fluconazole results in increased expression of CYP1A2 mRNA CTD PMID:16730040 Cyp1a2 Rat fludioxonil increases expression ISO CYP1A2 (Homo sapiens) 6480464 fludioxonil results in increased expression of CYP1A2 mRNA CTD PMID:33575850 Cyp1a2 Rat fludioxonil multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [difenoconazole co-treated with fludioxonil] results in increased expression of CYP1A2 mRNA more ... CTD PMID:33575850 Cyp1a2 Rat flumequine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [flumequine co-treated with 2-amino-3 more ... CTD PMID:23681119 and PMID:31029721 Cyp1a2 Rat fluoranthene increases expression ISO CYP1A2 (Homo sapiens) 6480464 fluoranthene results in increased expression of CYP1A2 mRNA CTD PMID:12107646 and PMID:21784029 Cyp1a2 Rat fluoranthene multiple interactions EXP 6480464 [1 more ... CTD PMID:18711122 Cyp1a2 Rat fluoranthene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat fluorene increases activity ISO Cyp1a2 (Mus musculus) 6480464 fluorene results in increased activity of CYP1A2 protein CTD PMID:8001243 Cyp1a2 Rat fluorene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA CTD PMID:7750161 Cyp1a2 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of CYP1A2 mRNA CTD PMID:24136188 and PMID:26485406 Cyp1a2 Rat flutamide increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to Flutamide CTD PMID:28762043 Cyp1a2 Rat flutamide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Flutamide CTD PMID:23397584 Cyp1a2 Rat flutriafol increases expression ISO CYP1A2 (Homo sapiens) 6480464 flutriafol results in increased expression of CYP1A2 mRNA CTD PMID:34200939 Cyp1a2 Rat flutriafol increases expression EXP 6480464 flutriafol results in increased expression of CYP1A2 mRNA CTD PMID:34200939 Cyp1a2 Rat flutriafol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP1A2 mRNA] CTD PMID:34200939 Cyp1a2 Rat fluvoxamine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite more ... CTD PMID:15545309 more ... Cyp1a2 Rat fluvoxamine increases expression ISO CYP1A2 (Homo sapiens) 401976472 fluvoxamine increases expression of CYP1A2 mRNA and protein in cervical cancer cells RGD Cyp1a2 Rat fluvoxamine decreases activity EXP 6480464 Fluvoxamine results in decreased activity of CYP1A2 protein CTD PMID:26599973 Cyp1a2 Rat fluvoxamine multiple interactions EXP 6480464 [Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Caffeine CTD PMID:26599973 Cyp1a2 Rat fluvoxamine increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to Fluvoxamine CTD PMID:18809730 Cyp1a2 Rat fluvoxamine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Fluvoxamine results in decreased activity of CYP1A2 protein CTD PMID:11763009 more ... Cyp1a2 Rat folic acid multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in decreased expression of CYP1A2 mRNA CTD PMID:29127188 Cyp1a2 Rat fonofos multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Fonofos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol] and Fonofos inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol] CTD PMID:16790556 Cyp1a2 Rat fonofos decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Fonofos results in decreased activity of CYP1A2 protein CTD PMID:16790556 Cyp1a2 Rat formononetin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 formononetin results in decreased activity of CYP1A2 protein CTD PMID:26278343 Cyp1a2 Rat formononetin decreases activity EXP 6480464 formononetin results in decreased activity of CYP1A2 protein CTD PMID:26278343 Cyp1a2 Rat Frangulin A multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [frangulin A co-treated with frangulin B] results in decreased activity of CYP1A2 protein CTD PMID:33438235 Cyp1a2 Rat Frangulin B multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [frangulin A co-treated with frangulin B] results in decreased activity of CYP1A2 protein CTD PMID:33438235 Cyp1a2 Rat fructose multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA more ... CTD PMID:26102010 Cyp1a2 Rat Furafylline decreases activity EXP 6480464 furafylline results in decreased activity of CYP1A2 protein CTD PMID:12814958 and PMID:15879494 Cyp1a2 Rat Furafylline decreases activity ISO CYP1A2 (Homo sapiens) 6480464 furafylline results in decreased activity of CYP1A2 protein CTD PMID:12467917 more ... Cyp1a2 Rat Furafylline multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [furafylline results in decreased activity of CYP1A2 protein] which results in decreased susceptibility to 2-amino-9H-pyrido(2 more ... CTD PMID:10215755 more ... Cyp1a2 Rat Furafylline multiple interactions EXP 6480464 [furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride and furafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 and PMID:20669986 Cyp1a2 Rat Furafylline multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [furafylline results in decreased activity of CYP1A2 protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]] more ... CTD PMID:21932800 and PMID:22491429 Cyp1a2 Rat furan decreases expression EXP 6480464 furan results in decreased expression of CYP1A2 mRNA CTD PMID:25539665 Cyp1a2 Rat gadolinium trichloride multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP1A2 protein] CTD PMID:18202523 Cyp1a2 Rat galangin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 galangin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:17090139 Cyp1a2 Rat galangin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 galangin results in decreased activity of CYP1A2 protein CTD PMID:20806393 and PMID:21053930 Cyp1a2 Rat gallocatechin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP1A2 mRNA CTD PMID:25663641 Cyp1a2 Rat gamma-decalactone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 decan-4-olide results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat gamma-hexachlorocyclohexane increases activity EXP 6480464 Hexachlorocyclohexane results in increased activity of CYP1A2 protein CTD PMID:12842176 and PMID:16641539 Cyp1a2 Rat gamma-hexachlorocyclohexane multiple interactions EXP 6480464 Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein more ... CTD PMID:18486174 Cyp1a2 Rat gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of CYP1A2 mRNA and Hexachlorocyclohexane results in increased expression of CYP1A2 protein CTD PMID:12842176 more ... Cyp1a2 Rat gamma-valerolactone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 gamma-valerolactone results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat gemfibrozil decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Gemfibrozil results in decreased activity of CYP1A2 protein CTD PMID:26599973 Cyp1a2 Rat gemfibrozil multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Gemfibrozil results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine CTD PMID:26599973 Cyp1a2 Rat genistein increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of Genistein CTD PMID:12814970 Cyp1a2 Rat genistein decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Genistein results in decreased activity of CYP1A2 protein CTD PMID:20806393 more ... Cyp1a2 Rat genistein decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Genistein results in decreased expression of CYP1A2 mRNA CTD PMID:24967385 Cyp1a2 Rat genistein increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Genistein CTD PMID:12814970 Cyp1a2 Rat genistein increases hydroxylation EXP 6480464 CYP1A2 protein results in increased hydroxylation of Genistein CTD PMID:15587933 Cyp1a2 Rat genkwanin increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of genkwanin CTD PMID:19666078 Cyp1a2 Rat gentamycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 Cyp1a2 Rat gestodene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein] which results in decreased metabolism of tizanidine more ... CTD PMID:16198659 and PMID:9305587 Cyp1a2 Rat Ginkgolide A increases activity EXP 6480464 ginkgolide A results in increased activity of CYP1A2 protein CTD PMID:18421621 Cyp1a2 Rat Ginkgolide A increases expression EXP 6480464 ginkgolide A results in increased expression of CYP1A2 mRNA CTD PMID:18421621 Cyp1a2 Rat ginkgolide B multiple interactions EXP 6480464 ginkgolide B results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:18421621 Cyp1a2 Rat ginkgolide B increases expression EXP 6480464 ginkgolide B results in increased expression of CYP1A2 mRNA CTD PMID:18421621 Cyp1a2 Rat Glu-P-1 affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 2-amino-6-methyldipyrido(1 more ... CTD PMID:2655891 Cyp1a2 Rat Glu-P-1 multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-6-methyldipyrido(1 more ... CTD PMID:28160022 Cyp1a2 Rat Glu-P-1 increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of 2-amino-6-methyldipyrido(1 more ... CTD PMID:14725854 Cyp1a2 Rat Glu-P-2 affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Glu-P-2 CTD PMID:2655891 Cyp1a2 Rat Glu-P-2 increases expression ISO CYP1A2 (Homo sapiens) 6480464 Glu-P-2 results in increased expression of CYP1A2 mRNA CTD PMID:27644595 Cyp1a2 Rat Glu-P-2 multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Glu-P-2 CTD PMID:28160022 Cyp1a2 Rat glucoerucin increases expression EXP 6480464 glucoerucin results in increased expression of CYP1A2 protein CTD PMID:20833222 Cyp1a2 Rat glucoerucin(1-) increases expression EXP 6480464 glucoerucin results in increased expression of CYP1A2 protein CTD PMID:20833222 Cyp1a2 Rat glucoraphanin increases expression EXP 6480464 glucoraphanin results in increased expression of CYP1A2 protein CTD PMID:20833222 Cyp1a2 Rat glucose multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31776611 Cyp1a2 Rat glutathione multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac more ... CTD PMID:20825217 more ... Cyp1a2 Rat glycochenodeoxycholic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of CYP1A2 mRNA more ... CTD PMID:33819548 Cyp1a2 Rat glycocholic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of CYP1A2 mRNA more ... CTD PMID:33819548 Cyp1a2 Rat glycodeoxycholic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of CYP1A2 mRNA more ... CTD PMID:33819548 Cyp1a2 Rat glycyrrhetinate multiple interactions EXP 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein CTD PMID:21800547 Cyp1a2 Rat glycyrrhetinic acid multiple interactions EXP 6480464 [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein CTD PMID:21800547 Cyp1a2 Rat griseofulvin affects expression ISO Cyp1a2 (Mus musculus) 6480464 Griseofulvin affects the expression of CYP1A2 mRNA CTD PMID:12735108 Cyp1a2 Rat griseofulvin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Griseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline] CTD PMID:9029748 Cyp1a2 Rat guanethidine multiple interactions EXP 6480464 Guanethidine inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein] CTD PMID:16510159 Cyp1a2 Rat GW 3965 increases expression ISO CYP1A2 (Homo sapiens) 6480464 GW 3965 results in increased expression of CYP1A2 mRNA CTD PMID:23041609 Cyp1a2 Rat halocarban increases expression ISO CYP1A2 (Homo sapiens) 6480464 cloflucarban results in increased expression of CYP1A2 mRNA and cloflucarban results in increased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat hemin multiple interactions EXP 6480464 [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in decreased expression of CYP1A2 protein more ... CTD PMID:22159698 and PMID:26747958 Cyp1a2 Rat heroin decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Heroin results in decreased activity of CYP1A2 protein CTD PMID:35914676 Cyp1a2 Rat hesperetin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 hesperetin results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of CYP1A2 mRNA and Hexachlorobenzene results in increased expression of CYP1A2 protein CTD PMID:10696772 more ... Cyp1a2 Rat hexane increases hydroxylation EXP 6480464 CYP1A2 protein results in increased hydroxylation of n-hexane CTD PMID:16484137 Cyp1a2 Rat hexane multiple interactions EXP 6480464 diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein] and n-hexane results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:28115069 Cyp1a2 Rat huperzine A increases metabolic processing EXP 6480464 CYP1A2 protein results in increased metabolism of huperzine A CTD PMID:12586202 Cyp1a2 Rat hydralazine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Hydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat hydralazine multiple interactions EXP 6480464 Hydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat hydrocortisone succinate multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A2 CTD PMID:18347083 Cyp1a2 Rat hydrogen peroxide increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of Hydrogen Peroxide CTD PMID:25061110 Cyp1a2 Rat hydrogen peroxide increases expression ISO CYP1A2 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of CYP1A2 mRNA and Hydrogen Peroxide results in increased expression of CYP1A2 protein CTD PMID:36368423 Cyp1a2 Rat hydrogen peroxide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Hydrogen Peroxide results in increased expression of CYP1A2 mRNA] CTD PMID:36368423 Cyp1a2 Rat Hypaconitine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of hypaconitine CTD PMID:21550385 Cyp1a2 Rat iberin multiple interactions EXP 6480464 iberin results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein] CTD PMID:22664424 Cyp1a2 Rat ibuprofen decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Ibuprofen results in decreased expression of CYP1A2 mRNA CTD PMID:25596134 Cyp1a2 Rat Icaritin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 icaritin results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat ifosfamide increases expression ISO CYP1A2 (Homo sapiens) 6480464 Ifosfamide results in increased expression of CYP1A2 mRNA CTD PMID:25596134 Cyp1a2 Rat imipramine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Imipramine CTD PMID:15286053 Cyp1a2 Rat imipramine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Imipramine CTD PMID:11714871 Cyp1a2 Rat imipramine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of and results in increased activity of Imipramine more ... CTD PMID:11714871 and PMID:15922009 Cyp1a2 Rat imipramine oxide increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of imipramine N-oxide CTD PMID:27320963 Cyp1a2 Rat imiprothrin increases expression EXP 6480464 imiprothrin results in increased expression of CYP1A2 mRNA CTD PMID:33638779 Cyp1a2 Rat imiquimod multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod] CTD PMID:31111189 Cyp1a2 Rat imiquimod affects metabolic processing ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein affects the metabolism of Imiquimod CTD PMID:31111189 Cyp1a2 Rat imiquimod increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of Imiquimod metabolite CTD PMID:31111189 Cyp1a2 Rat imiquimod increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Imiquimod CTD PMID:31111189 Cyp1a2 Rat imiquimod multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of Imiquimod] which results in increased chemical synthesis of Imiquimod metabolite CTD PMID:31111189 Cyp1a2 Rat imperatorin increases expression ISO Cyp1a2 (Mus musculus) 6480464 imperatorin results in increased expression of CYP1A2 protein CTD PMID:18692084 Cyp1a2 Rat indane decreases activity ISO CYP1A2 (Homo sapiens) 6480464 indan results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat Indeno[1,2,3-cd]pyrene increases expression ISO CYP1A2 (Homo sapiens) 6480464 indeno(1 more ... CTD PMID:17253728 Cyp1a2 Rat indirubin increases expression ISO CYP1A2 (Homo sapiens) 6480464 indirubin results in increased expression of CYP1A2 mRNA CTD PMID:15056799 Cyp1a2 Rat indole-3-methanol increases expression ISO CYP1A2 (Homo sapiens) 6480464 indole-3-carbinol results in increased expression of CYP1A2 mRNA CTD PMID:28357125 Cyp1a2 Rat indole-3-methanol increases expression EXP 6480464 indole-3-carbinol results in increased expression of CYP1A2 and indole-3-carbinol results in increased expression of CYP1A2 protein CTD PMID:22328411 more ... Cyp1a2 Rat indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA and Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] CTD PMID:22129741 Cyp1a2 Rat indole-3-methanol increases expression ISO Cyp1a2 (Mus musculus) 6480464 indole-3-carbinol results in increased expression of CYP1A2 CTD PMID:22328411 Cyp1a2 Rat indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of CYP1A2 mRNA CTD PMID:21396975 Cyp1a2 Rat indole-3-methanol increases activity EXP 6480464 indole-3-carbinol results in increased activity of CYP1A2 and indole-3-carbinol results in increased activity of CYP1A2 protein CTD PMID:12147290 Cyp1a2 Rat indolin-2-one increases expression ISO CYP1A2 (Homo sapiens) 6480464 2-oxindole results in increased expression of CYP1A2 protein CTD PMID:36368423 Cyp1a2 Rat indolin-2-one multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-oxindole results in increased expression of CYP1A2 protein] and IFNG protein inhibits the reaction [2-oxindole results in increased expression of CYP1A2 protein] CTD PMID:36368423 Cyp1a2 Rat indometacin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 TLR4 protein affects the reaction [Indomethacin results in decreased activity of CYP1A2 protein] CTD PMID:12927920 Cyp1a2 Rat indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of CYP1A2 mRNA CTD PMID:16771604 Cyp1a2 Rat indoxyl sulfate increases expression ISO CYP1A2 (Homo sapiens) 6480464 Indican results in increased expression of CYP1A2 mRNA CTD PMID:20000589 Cyp1a2 Rat indoxyl sulfate multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Indican results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:38670245 Cyp1a2 Rat indoxyl sulfate multiple interactions EXP 6480464 Indican results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:38670245 Cyp1a2 Rat inulin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CYP1A2 mRNA CTD PMID:36331819 Cyp1a2 Rat irilone decreases activity ISO CYP1A2 (Homo sapiens) 6480464 irilone results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat iron dextran decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Iron-Dextran Complex results in decreased activity of CYP1A2 protein CTD PMID:9443932 Cyp1a2 Rat iron dextran multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Iron-Dextran Complex inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:9443932 Cyp1a2 Rat isocarbophos multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of and results in decreased sulfation of and affects the activity of isocarbophos CTD PMID:24752505 Cyp1a2 Rat isoimperatorin increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of isoimperatorin CTD PMID:25500267 Cyp1a2 Rat isoliquiritigenin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 isoliquiritigenin inhibits the reaction [9 more ... CTD PMID:25110319 Cyp1a2 Rat isoliquiritigenin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 isoliquiritigenin results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat isopimpinellin increases expression ISO Cyp1a2 (Mus musculus) 6480464 isopimpinellin results in increased expression of CYP1A2 protein CTD PMID:18692084 Cyp1a2 Rat isoprenaline multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Isoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat isoprenaline multiple interactions EXP 6480464 Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein] and Propranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]] CTD PMID:15710352 Cyp1a2 Rat isoproturon increases activity ISO CYP1A2 (Homo sapiens) 6480464 isoproturon results in increased activity of CYP1A2 protein CTD PMID:22310298 Cyp1a2 Rat isoproturon decreases activity ISO Cyp1a2 (Mus musculus) 6480464 isoproturon results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat isoproturon increases expression ISO CYP1A2 (Homo sapiens) 6480464 isoproturon results in increased expression of CYP1A2 mRNA CTD PMID:22310298 Cyp1a2 Rat Isosafrole multiple interactions EXP 6480464 isosafrole inhibits the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane] CTD PMID:12062927 Cyp1a2 Rat Isosafrole decreases activity EXP 6480464 isosafrole results in decreased activity of CYP1A2 protein CTD PMID:12062927 Cyp1a2 Rat Isosafrole increases expression EXP 6480464 isosafrole results in increased expression of CYP1A2 mRNA CTD PMID:11285323 Cyp1a2 Rat Isosafrole increases expression ISO Cyp1a2 (Mus musculus) 6480464 isosafrole results in increased expression of CYP1A2 mRNA CTD PMID:8722114 Cyp1a2 Rat Isoxanthohumol increases expression ISO CYP1A2 (Homo sapiens) 6480464 isoxanthohumol results in increased expression of CYP1A2 mRNA CTD PMID:15672752 Cyp1a2 Rat Isradipine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Isradipine results in increased expression of CYP1A2 mRNA CTD PMID:27732883 Cyp1a2 Rat ivermectin increases expression ISO Cyp1a2 (Mus musculus) 6480464 Ivermectin results in increased expression of CYP1A2 mRNA CTD PMID:24998875 Cyp1a2 Rat kaempferol increases expression ISO CYP1A2 (Homo sapiens) 6480464 kaempferol results in increased expression of CYP1A2 mRNA CTD PMID:19034627 Cyp1a2 Rat kaempferol decreases activity ISO CYP1A2 (Homo sapiens) 6480464 kaempferol results in decreased activity of CYP1A2 protein CTD PMID:20806393 more ... Cyp1a2 Rat kaempferol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 kaempferol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:21256954 Cyp1a2 Rat kaempferol increases expression EXP 6480464 kaempferol results in increased expression of CYP1A2 mRNA CTD PMID:18421621 Cyp1a2 Rat kaempferol multiple interactions EXP 6480464 kaempferol results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:18421621 Cyp1a2 Rat ketoconazole multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Ketoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] and Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines] CTD PMID:24120545 and PMID:9305587 Cyp1a2 Rat ketoconazole decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Ketoconazole results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat ketoconazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 Ketoconazole results in increased expression of CYP1A2 mRNA and Ketoconazole results in increased expression of CYP1A2 protein CTD PMID:25000292 Cyp1a2 Rat ketoconazole decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Ketoconazole results in decreased activity of CYP1A2 protein CTD PMID:15618748 and PMID:15916432 Cyp1a2 Rat ketoconazole decreases activity EXP 6480464 Ketoconazole results in decreased activity of CYP1A2 protein CTD PMID:12814958 and PMID:15879494 Cyp1a2 Rat ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin] CTD PMID:19858067 Cyp1a2 Rat ketoconazole multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Ketoconazole inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens] CTD PMID:1567206 Cyp1a2 Rat L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid deficiency results in increased expression of CYP1A2 mRNA and Ascorbic Acid deficiency results in increased expression of CYP1A2 protein CTD PMID:8269614 Cyp1a2 Rat L-methionine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [3 more ... CTD PMID:27712037 more ... Cyp1a2 Rat L-methionine multiple interactions EXP 6480464 [Choline deficiency co-treated with Methionine deficiency] results in decreased activity of CYP1A2 protein and [Choline deficiency co-treated with Methionine deficiency] results in decreased expression of CYP1A2 mRNA CTD PMID:38663832 Cyp1a2 Rat lansoprazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 Lansoprazole results in increased expression of CYP1A2 mRNA and Lansoprazole results in increased expression of CYP1A2 protein CTD PMID:12623754 more ... Cyp1a2 Rat lansoprazole increases expression EXP 6480464 Lansoprazole results in increased expression of CYP1A2 mRNA and Lansoprazole results in increased expression of CYP1A2 protein CTD PMID:14550749 more ... Cyp1a2 Rat laquinimod increases expression EXP 6480464 laquinimod analog results in increased expression of CYP1A2 mRNA CTD PMID:28433708 Cyp1a2 Rat lead nitrate decreases activity ISO CYP1A2 (Homo sapiens) 6480464 lead nitrate results in decreased activity of CYP1A2 protein CTD PMID:11162773 Cyp1a2 Rat lead nitrate multiple interactions EXP 6480464 lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:8902619 Cyp1a2 Rat lead(0) affects expression EXP 6480464 Lead affects the expression of CYP1A2 mRNA CTD PMID:23631153 Cyp1a2 Rat lefetamine decreases alkylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased alkylation of lephetamine CTD PMID:26276083 Cyp1a2 Rat leflunomide increases expression ISO CYP1A2 (Homo sapiens) 6480464 leflunomide results in increased expression of CYP1A2 mRNA CTD PMID:28988120 Cyp1a2 Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of CYP1A2 mRNA CTD PMID:24136188 Cyp1a2 Rat lentinan decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Lentinan results in decreased expression of CYP1A2 CTD PMID:15630237 Cyp1a2 Rat Licochalcone A decreases activity ISO CYP1A2 (Homo sapiens) 6480464 licochalcone A results in decreased activity of CYP1A2 protein CTD PMID:26100226 Cyp1a2 Rat lidocaine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Lidocaine CTD PMID:15447735 Cyp1a2 Rat linoleic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Linoleic Acid results in decreased activity of CYP1A2 protein CTD PMID:16978661 Cyp1a2 Rat linuron decreases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased susceptibility to Linuron CTD PMID:29573710 Cyp1a2 Rat lipoic acid multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]] CTD PMID:21932800 Cyp1a2 Rat lipoic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Thioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid] CTD PMID:24120545 Cyp1a2 Rat lipopolysaccharide multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 Lipopolysaccharides inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:22466549 Cyp1a2 Rat lipopolysaccharide decreases activity EXP 6480464 Lipopolysaccharides results in decreased activity of CYP1A2 protein CTD PMID:15542068 and PMID:15710352 Cyp1a2 Rat lipopolysaccharide multiple interactions EXP 6480464 Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein] more ... CTD PMID:15542068 and PMID:15710352 Cyp1a2 Rat lithocholic acid decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Lithocholic Acid results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat lithocholic acid increases metabolic processing EXP 6480464 CYP1A2 protein results in increased metabolism of Lithocholic Acid CTD PMID:18039809 Cyp1a2 Rat lithocholic acid multiple interactions EXP 6480464 [CYP1A2 protein results in increased metabolism of Lithocholic Acid] which results in increased chemical synthesis of Lithocholic Acid analog CTD PMID:18039809 Cyp1a2 Rat loxapine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 results in increased metabolism of Loxapine CTD PMID:21826677 Cyp1a2 Rat luteolin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Luteolin results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat luteolin decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Luteolin results in decreased expression of CYP1A2 protein CTD PMID:33727136 Cyp1a2 Rat luteolin increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to Luteolin CTD PMID:33727136 Cyp1a2 Rat luteolin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased susceptibility to Luteolin] which results in decreased abundance of diosmetin more ... CTD PMID:33727136 Cyp1a2 Rat Luteolin 7-methyl ether decreases activity ISO CYP1A2 (Homo sapiens) 6480464 hydroxygenkwanin results in decreased activity of CYP1A2 protein CTD PMID:34843882 Cyp1a2 Rat Luteolin 7-methyl ether decreases activity EXP 6480464 hydroxygenkwanin results in decreased activity of CYP1A2 protein CTD PMID:34843882 Cyp1a2 Rat lycopene multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Lycopene co-treated with Atrazine] results in increased expression of CYP1A2 mRNA more ... CTD PMID:26775023 more ... Cyp1a2 Rat lycopene increases expression ISO Cyp1a2 (Mus musculus) 6480464 Lycopene results in increased expression of CYP1A2 mRNA CTD PMID:36216167 Cyp1a2 Rat m-xylene decreases activity EXP 6480464 3-xylene results in decreased activity of CYP1A2 protein CTD PMID:8598570 Cyp1a2 Rat m-xylene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 furafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-xylene] CTD PMID:8558417 Cyp1a2 Rat m-xylene increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of 3-xylene CTD PMID:8558417 Cyp1a2 Rat Magnolol decreases activity ISO Cyp1a2 (Mus musculus) 6480464 magnolol results in decreased activity of CYP1A2 protein CTD PMID:19140158 Cyp1a2 Rat malathion affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Malathion CTD PMID:15557345 Cyp1a2 Rat malathion increases expression ISO CYP1A2 (Homo sapiens) 6480464 Malathion results in increased expression of CYP1A2 mRNA CTD PMID:22310298 Cyp1a2 Rat maneb multiple interactions EXP 6480464 [Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein more ... CTD PMID:23159886 Cyp1a2 Rat mangiferin decreases activity EXP 6480464 mangiferin results in decreased activity of CYP1A2 protein CTD PMID:18053976 Cyp1a2 Rat mangiferin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 mangiferin results in decreased activity of CYP1A2 protein CTD PMID:22815239 Cyp1a2 Rat mangiferin increases expression ISO CYP1A2 (Homo sapiens) 6480464 mangiferin results in increased expression of CYP1A2 mRNA CTD PMID:22815239 Cyp1a2 Rat mebendazole increases expression ISO CYP1A2 (Homo sapiens) 6480464 Mebendazole results in increased expression of CYP1A2 protein CTD PMID:12841937 Cyp1a2 Rat mebendazole increases expression EXP 6480464 Mebendazole results in increased expression of CYP1A2 protein CTD PMID:12841937 Cyp1a2 Rat Meclizine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Meclizine inhibits the reaction [[Phenobarbital results in increased activity of NR1I3 protein] which results in increased expression of CYP1A2 mRNA] CTD PMID:15272053 Cyp1a2 Rat Meclizine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Meclizine binds to and results in increased activity of NR1I3 protein] which results in increased expression of CYP1A2 mRNA CTD PMID:15272053 Cyp1a2 Rat mefenamic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Mefenamic Acid results in decreased activity of CYP1A2 protein CTD PMID:18816299 Cyp1a2 Rat mefenamic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 SOD1 protein inhibits the reaction [CYP1A2 protein results in increased oxidation of Mefenamic Acid] CTD PMID:33259822 Cyp1a2 Rat mefenamic acid increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of Mefenamic Acid CTD PMID:33259822 Cyp1a2 Rat mefenamic acid increases glutathionylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased glutathionylation of Mefenamic Acid analog CTD PMID:25372302 Cyp1a2 Rat mefenamic acid increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Mefenamic Acid CTD PMID:25372302 Cyp1a2 Rat MeIQ increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein mutant form results in increased metabolism of 2-amino-3 more ... CTD PMID:14744142 Cyp1a2 Rat MeIQ multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] which results in increased activity of 2-amino-3 more ... CTD PMID:11585058 Cyp1a2 Rat MeIQ multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 2-amino-3 more ... CTD PMID:1567206 Cyp1a2 Rat MeIQ decreases activity EXP 6480464 2-amino-3 more ... CTD PMID:1617633 Cyp1a2 Rat MeIQ affects expression EXP 6480464 2-amino-3 more ... CTD PMID:1617633 Cyp1a2 Rat MeIQ increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of 2-amino-3 more ... CTD PMID:14725854 Cyp1a2 Rat MeIQ increases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 results in increased activity of 2-amino-3 more ... CTD PMID:10775323 more ... Cyp1a2 Rat MeIQ affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 2-amino-3 more ... CTD PMID:2655891 Cyp1a2 Rat MeIQ multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3 more ... CTD PMID:10503888 more ... Cyp1a2 Rat MeIQ increases metabolic processing EXP 6480464 CYP1A2 protein results in increased metabolism of 2-amino-3 more ... CTD PMID:1617633 Cyp1a2 Rat MeIQ affects binding ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein binds to 2-amino-3 more ... CTD PMID:9334905 Cyp1a2 Rat MeIQx increases expression ISO Cyp1a2 (Mus musculus) 6480464 2-amino-3 more ... CTD PMID:23681119 Cyp1a2 Rat MeIQx increases expression ISO CYP1A2 (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:20307560 more ... Cyp1a2 Rat MeIQx increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 2-amino-3 more ... CTD PMID:10503887 more ... Cyp1a2 Rat MeIQx multiple interactions EXP 6480464 2-amino-3 more ... CTD PMID:12079509 more ... Cyp1a2 Rat MeIQx affects oxidation EXP 6480464 CYP1A2 affects the oxidation of 2-amino-3 more ... CTD PMID:10503887 Cyp1a2 Rat MeIQx increases activity ISO CYP1A2 (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:20307560 and PMID:2334931 Cyp1a2 Rat MeIQx affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of 2-amino-3 more ... CTD PMID:2655891 Cyp1a2 Rat MeIQx decreases activity ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased activity of 2-amino-3 more ... CTD PMID:20192249 Cyp1a2 Rat MeIQx increases expression EXP 6480464 2-amino-3 more ... CTD PMID:12079509 more ... Cyp1a2 Rat MeIQx multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:10503888 more ... Cyp1a2 Rat MeIQx multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [flumequine co-treated with 2-amino-3 more ... CTD PMID:23681119 Cyp1a2 Rat melatonin decreases methylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of Melatonin CTD PMID:15616152 Cyp1a2 Rat melatonin multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [ABCB6 gene mutant form results in decreased expression of CYP1A2 mRNA] inhibits the reaction [CYP1A2 protein results in increased metabolism of Melatonin] and [ABCB6 gene mutant form results in decreased expression of CYP1A2 protein] inhibits the reaction [CYP1A2 protein results in increased metabolism of Melatonin] CTD PMID:25623066 Cyp1a2 Rat melatonin increases metabolic processing ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased metabolism of Melatonin CTD PMID:25623066 Cyp1a2 Rat melatonin increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Melatonin CTD PMID:15616152 and PMID:22634058 Cyp1a2 Rat melatonin affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Melatonin CTD PMID:15626586 and PMID:15824912 Cyp1a2 Rat melatonin multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of CYP1A2 mRNA CTD PMID:20033131 Cyp1a2 Rat melatonin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Melatonin results in decreased activity of CYP1A2 protein CTD PMID:19919601 Cyp1a2 Rat melatonin increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of Melatonin CTD PMID:17565714 Cyp1a2 Rat melatonin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Melatonin inhibits the reaction [CYP1A2 protein results in increased hydrolysis of Benzo(a)pyrene] CTD PMID:19919601 Cyp1a2 Rat meloxicam multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Meloxicam] which results in increased chemical synthesis of Pyruvaldehyde and CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Meloxicam CTD PMID:33253783 Cyp1a2 Rat melphalan multiple interactions EXP 6480464 Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat melphalan multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat menadione multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat menadione increases expression EXP 6480464 Vitamin K 3 results in increased expression of CYP1A2 mRNA CTD PMID:15603920 Cyp1a2 Rat menadione increases activity EXP 6480464 Vitamin K 3 results in increased activity of CYP1A2 protein CTD PMID:15603920 Cyp1a2 Rat menadione multiple interactions EXP 6480464 Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat mercury atom multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] more ... CTD PMID:22579925 more ... Cyp1a2 Rat mercury atom increases activity ISO Cyp1a2 (Mus musculus) 6480464 Mercury results in increased activity of CYP1A2 protein CTD PMID:22579925 Cyp1a2 Rat mercury dichloride decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Mercuric Chloride results in decreased activity of CYP1A2 protein CTD PMID:11162773 Cyp1a2 Rat mercury dichloride decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Mercuric Chloride results in decreased expression of CYP1A2 protein CTD PMID:37172713 Cyp1a2 Rat mercury dichloride decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Mercuric Chloride results in decreased expression of CYP1A2 protein CTD PMID:37172713 Cyp1a2 Rat mercury(0) multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] more ... CTD PMID:22579925 more ... Cyp1a2 Rat mercury(0) increases activity ISO Cyp1a2 (Mus musculus) 6480464 Mercury results in increased activity of CYP1A2 protein CTD PMID:22579925 Cyp1a2 Rat metformin increases expression ISO CYP1A2 (Homo sapiens) 6480464 Metformin results in increased expression of CYP1A2 mRNA CTD PMID:19022234 Cyp1a2 Rat metformin decreases expression EXP 6480464 Metformin results in decreased expression of CYP1A2 mRNA CTD PMID:25596134 Cyp1a2 Rat methamphetamine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of Methamphetamine metabolite CTD PMID:16038959 Cyp1a2 Rat methidathion increases expression ISO Cyp1a2 (Mus musculus) 6480464 methidathion results in increased expression of CYP1A2 mRNA CTD PMID:34813904 Cyp1a2 Rat methotrexate multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Methotrexate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of CYP1A2 mRNA CTD PMID:15120968 Cyp1a2 Rat methoxsalen decreases activity EXP 6480464 Methoxsalen results in decreased activity of CYP1A2 protein CTD PMID:12814958 and PMID:15879494 Cyp1a2 Rat methoxsalen decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Methoxsalen results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat methoxsalen decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Methoxsalen results in decreased activity of CYP1A2 protein CTD PMID:8819299 Cyp1a2 Rat methoxychlor multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 ESR1 protein promotes the reaction [Methoxychlor results in increased expression of CYP1A2 mRNA] CTD PMID:21252393 Cyp1a2 Rat methoxychlor increases expression ISO CYP1A2 (Homo sapiens) 6480464 Methoxychlor results in increased expression of CYP1A2 mRNA CTD PMID:21924250 Cyp1a2 Rat methoxychlor decreases methylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in decreased methylation of Methoxychlor CTD PMID:12167570 more ... Cyp1a2 Rat methoxychlor multiple interactions EXP 6480464 Methoxychlor results in increased expression of and results in increased activity of CYP1A2 protein CTD PMID:12919727 Cyp1a2 Rat methoxychlor increases expression ISO Cyp1a2 (Mus musculus) 6480464 Methoxychlor results in increased expression of CYP1A2 mRNA CTD PMID:21252393 Cyp1a2 Rat methoxychlor increases hydroxylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased hydroxylation of Methoxychlor CTD PMID:9047321 Cyp1a2 Rat methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Nisoldipine results in decreased activity of CYP1A2 protein CTD PMID:10805063 Cyp1a2 Rat methylarsonic acid increases expression EXP 6480464 monomethylarsonic acid results in increased expression of CYP1A2 mRNA CTD PMID:17481689 Cyp1a2 Rat methylglyoxal multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Meloxicam] which results in increased chemical synthesis of Pyruvaldehyde CTD PMID:33253783 Cyp1a2 Rat methylmercury chloride multiple interactions EXP 6480464 [Hydrocarbons and Chlorinated co-treated with Polychlorinated Biphenyls co-treated with methylmercuric chloride] results in increased expression of CYP1A2 mRNA CTD PMID:30744511 Cyp1a2 Rat methylmercury chloride multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] more ... CTD PMID:36245390 Cyp1a2 Rat metolachlor increases activity ISO CYP1A2 (Homo sapiens) 6480464 metolachlor results in increased activity of CYP1A2 protein CTD PMID:10813365 Cyp1a2 Rat metronidazole multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 Cyp1a2 Rat miconazole increases expression EXP 6480464 Miconazole results in increased expression of CYP1A2 mRNA CTD PMID:22262564 Cyp1a2 Rat microcystin-LR increases expression ISO Cyp1a2 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of CYP1A2 mRNA CTD PMID:17383702 Cyp1a2 Rat mifepristone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein] more ... CTD PMID:19022236 Cyp1a2 Rat mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]] CTD PMID:17690134 Cyp1a2 Rat mitomycin C decreases activity EXP 6480464 Mitomycin results in decreased activity of CYP1A2 protein CTD PMID:15696929 Cyp1a2 Rat Mitragynine increases activity ISO CYP1A2 (Homo sapiens) 6480464 mitragynine results in increased activity of CYP1A2 protein CTD PMID:23274770 Cyp1a2 Rat Mitragynine increases expression ISO CYP1A2 (Homo sapiens) 6480464 mitragynine results in increased expression of CYP1A2 mRNA and mitragynine results in increased expression of CYP1A2 protein CTD PMID:23274770 Cyp1a2 Rat Monobutylphthalate decreases activity EXP 6480464 monobutyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 Cyp1a2 Rat monocrotophos increases expression EXP 6480464 Monocrotophos results in increased expression of CYP1A2 protein CTD PMID:21445290 Cyp1a2 Rat monosodium L-glutamate multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Sodium Glutamate co-treated with gallocatechol co-treated with Catechin co-treated with epigallocatechin gallate co-treated with epicatechin gallate co-treated with gallocatechol co-treated with gallocatechin gallate] affects the expression of CYP1A2 mRNA and [Sodium Glutamate co-treated with Tea] affects the expression of CYP1A2 mRNA CTD PMID:25663641 Cyp1a2 Rat morphine decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Morphine results in decreased activity of CYP1A2 protein CTD PMID:35914676 Cyp1a2 Rat musk xylene increases expression EXP 6480464 musk xylene results in increased expression of CYP1A2 protein CTD PMID:10630706 Cyp1a2 Rat musk xylene increases activity EXP 6480464 musk xylene results in increased activity of CYP1A2 protein CTD PMID:10630706 Cyp1a2 Rat musk xylene increases expression ISO Cyp1a2 (Mus musculus) 6480464 musk xylene metabolite results in increased expression of CYP1A2 mRNA and musk xylene results in increased expression of CYP1A2 mRNA CTD PMID:9397191 Cyp1a2 Rat mycophenolic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Mycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] CTD PMID:25929522 Cyp1a2 Rat myricetin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 myricetin results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat myristicin affects oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the oxidation of myristicin CTD PMID:12523956 Cyp1a2 Rat myristicin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 myristicin results in decreased activity of CYP1A2 protein CTD PMID:26091900 Cyp1a2 Rat myristicin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Glutathione inhibits the reaction [myristicin results in decreased activity of CYP1A2 protein] CTD PMID:26091900 Cyp1a2 Rat N'-(2,4-dimethylphenyl)-N-methylformamidine increases expression EXP 6480464 U 40481 results in increased expression of CYP1A2 protein CTD PMID:31029719 Cyp1a2 Rat N,N-diethyl-m-toluamide increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of DEET CTD PMID:11854147 Cyp1a2 Rat N,N-diethyl-m-toluamide multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [fipronil co-treated with DEET] results in increased expression of CYP1A2 mRNA CTD PMID:27091632 Cyp1a2 Rat N,N-diethyl-m-toluamide increases expression ISO CYP1A2 (Homo sapiens) 6480464 DEET results in increased expression of CYP1A2 mRNA CTD PMID:19326769 and PMID:27091632 Cyp1a2 Rat N,N-diisopropyltryptamine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [N and N-diisopropyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin CTD PMID:26599973 Cyp1a2 Rat N,N-diisopropyltryptamine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 N and N-diisopropyltryptamine analog results in decreased activity of CYP1A2 protein CTD PMID:26599973 Cyp1a2 Rat N,N-dimethyltryptamine increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of N and N-Dimethyltryptamine CTD PMID:27320963 Cyp1a2 Rat N-[3-(aminomethyl)benzyl]acetamidine multiple interactions EXP 6480464 N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein] CTD PMID:15542068 Cyp1a2 Rat N-acetyl-1,4-benzoquinone imine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:19679878 Cyp1a2 Rat N-acetyl-1,4-benzoquinone imine increases abundance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased abundance of N-acetyl-4-benzoquinoneimine CTD PMID:24661219 Cyp1a2 Rat N-acetyl-L-cysteine multiple interactions EXP 6480464 [Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein] more ... CTD PMID:21424224 more ... Cyp1a2 Rat N-acetyl-L-cysteine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite and Acetylcysteine inhibits the reaction [flutriafol results in increased expression of CYP1A2 mRNA] CTD PMID:27989148 and PMID:34200939 Cyp1a2 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 401794136 MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats RGD Cyp1a2 Rat N-desmethylclozapine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of norclozapine and Fluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of norclozapine] CTD PMID:11151749 and PMID:18809730 Cyp1a2 Rat N-desmethylclozapine increases chemical synthesis ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased chemical synthesis of norclozapine CTD PMID:18809730 Cyp1a2 Rat N-desmethylclozapine increases metabolic processing ISO Cyp1a2 (Mus musculus) 6480464 CYP1A2 protein results in increased metabolism of norclozapine CTD PMID:12969762 Cyp1a2 Rat N-Desmethyltamoxifen increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of N-desmethyltamoxifen CTD PMID:29285606 Cyp1a2 Rat N-Desmethyltamoxifen multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of N-desmethyltamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1 and 2-diphenyl-1-butene CTD PMID:29285606 Cyp1a2 Rat N-hydroxy-PhIP multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:16167840 more ... Cyp1a2 Rat N-hydroxy-PhIP multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:1943715 Cyp1a2 Rat N-nitrosodiethylamine multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] which results in increased abundance of Reactive Oxygen Species and [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA CTD PMID:20118626 Cyp1a2 Rat N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of CYP1A2 mRNA CTD PMID:19638242 more ... Cyp1a2 Rat N-nitrosodiethylamine decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Diethylnitrosamine results in decreased expression of CYP1A2 mRNA CTD PMID:24535843 Cyp1a2 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA more ... CTD PMID:18164116 more ... Cyp1a2 Rat N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of CYP1A2 mRNA and Dimethylnitrosamine results in decreased expression of CYP1A2 protein CTD PMID:16997515 and PMID:17072980 Cyp1a2 Rat NADP zwitterion multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with NADP co-treated with Glutathione] results in increased glutathionylation of and results in increased activity of 7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1 more ... CTD PMID:11714871 more ... Cyp1a2 Rat NADP(+) multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein co-treated with NADP co-treated with Glutathione] results in increased glutathionylation of and results in increased activity of 7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1 more ... CTD PMID:11714871 more ... Cyp1a2 Rat naphthalene multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 naphthalene inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol] and naphthalene inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol] CTD PMID:16790556 Cyp1a2 Rat naphthalene decreases activity ISO CYP1A2 (Homo sapiens) 6480464 naphthalene analog results in decreased activity of CYP1A2 protein and naphthalene results in decreased activity of CYP1A2 protein CTD PMID:15916432 and PMID:16790556 Cyp1a2 Rat naringin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 naringin results in decreased activity of CYP1A2 protein CTD PMID:21053930 Cyp1a2 Rat nefazodone increases expression EXP 6480464 nefazodone results in increased expression of CYP1A2 mRNA CTD PMID:24136188 Cyp1a2 Rat nefazodone multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP1A2 mRNA CTD PMID:33819548 Cyp1a2 Rat neomycin multiple interactions EXP 6480464 [Ampicillin co-treated with Neomycin co-treated with Gentamicins co-treated with Metronidazole co-treated with Vancomycin] results in decreased expression of CYP1A2 mRNA CTD PMID:30545405 Cyp1a2 Rat nicardipine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A2 mRNA] and Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA] CTD PMID:20067464 Cyp1a2 Rat nicardipine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Nicardipine results in increased expression of CYP1A2 mRNA CTD PMID:20067464 Cyp1a2 Rat nicardipine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Nicardipine results in decreased activity of CYP1A2 protein CTD PMID:15863898 Cyp1a2 Rat nickel atom decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Nickel results in decreased expression of CYP1A2 mRNA CTD PMID:24768652 Cyp1a2 Rat nickel dichloride decreases expression ISO CYP1A2 (Homo sapiens) 6480464 nickel chloride results in decreased expression of CYP1A2 protein CTD PMID:21784029 Cyp1a2 Rat niclosamide decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Niclosamide results in decreased activity of CYP1A2 protein CTD PMID:11124226 Cyp1a2 Rat niclosamide increases expression ISO CYP1A2 (Homo sapiens) 6480464 Niclosamide results in increased expression of CYP1A2 mRNA CTD PMID:28284560 Cyp1a2 Rat nicotine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Nicotine results in decreased activity of CYP1A2 protein CTD PMID:15916432 Cyp1a2 Rat nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of CYP1A2 mRNA CTD PMID:26463278 Cyp1a2 Rat nicotine increases expression ISO CYP1A2 (Homo sapiens) 6480464 Nicotine results in increased expression of CYP1A2 protein CTD PMID:11849738 Cyp1a2 Rat nifedipine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Nifedipine results in decreased activity of CYP1A2 protein CTD PMID:10805063 Cyp1a2 Rat nifedipine decreases activity ISO Cyp1a2 (Mus musculus) 6480464 Nifedipine results in decreased activity of CYP1A2 protein CTD PMID:18420780 Cyp1a2 Rat nifedipine multiple interactions EXP 6480464 Nifedipine inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin] CTD PMID:19858067 Cyp1a2 Rat nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of CYP1A2 mRNA CTD PMID:24136188 Cyp1a2 Rat nimesulide increases glutathionylation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased glutathionylation of nimesulide CTD PMID:26524229 Cyp1a2 Rat nisoldipine decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Nisoldipine results in decreased activity of CYP1A2 protein CTD PMID:10805063 Cyp1a2 Rat nitroaniline increases expression EXP 6480464 nitroaniline analog results in increased expression of CYP1A2 mRNA and nitroaniline analog results in increased expression of CYP1A2 protein CTD PMID:9545601 Cyp1a2 Rat nitroaniline increases activity EXP 6480464 nitroaniline analog results in increased activity of CYP1A2 protein CTD PMID:9545601 Cyp1a2 Rat nitrofurantoin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Nitrofurantoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 Cyp1a2 Rat nitroglycerin affects expression EXP 401900296 Vitamin E inhibits the reaction [nitroglycerine decreases Cyp1a2 protein expression in rat heart] RGD Cyp1a2 Rat nitroglycerin decreases expression EXP 401900656 nitroglycerin decreased expression of Cyp1a2 protein in thoracic aorta of rats RGD Cyp1a2 Rat nobiletin increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of nobiletin CTD PMID:22743247 Cyp1a2 Rat Nonylphenol increases expression ISO CYP1A2 (Homo sapiens) 6480464 nonylphenol results in increased expression of CYP1A2 mRNA and nonylphenol results in increased expression of CYP1A2 protein CTD PMID:34974051 Cyp1a2 Rat norfloxacin affects binding EXP 6480464 Norfloxacin binds to CYP1A2 protein CTD PMID:8905919 Cyp1a2 Rat norfloxacin multiple interactions EXP 6480464 Norfloxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin] CTD PMID:8905919 Cyp1a2 Rat norgestimate multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP1A2 protein CTD PMID:16291717 Cyp1a2 Rat nortriptyline increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 Nortriptyline results in increased metabolism of CYP1A2 protein CTD PMID:18359012 Cyp1a2 Rat notoginsenoside R1 decreases activity EXP 6480464 notoginsenoside R1 results in decreased activity of CYP1A2 protein CTD PMID:25834921 Cyp1a2 Rat Notopterol increases metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of notopterol CTD PMID:32198085 Cyp1a2 Rat Notopterol multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [CYP1A2 protein results in increased metabolism of notopterol] promotes the reaction [Glutathione binds to notopterol] CTD PMID:32198085 Cyp1a2 Rat o-anisidine increases expression EXP 6480464 2-anisidine results in increased expression of CYP1A2 CTD PMID:11409192 Cyp1a2 Rat o-anisidine increases oxidation ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased oxidation of 2-anisidine CTD PMID:15828049 Cyp1a2 Rat O-methyleugenol increases expression ISO CYP1A2 (Homo sapiens) 6480464 methyleugenol results in increased expression of CYP1A2 mRNA CTD PMID:32234424 Cyp1a2 Rat obeticholic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 obeticholic acid inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of Acetaminophen] and obeticholic acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin] CTD PMID:27939613 Cyp1a2 Rat obeticholic acid decreases expression EXP 6480464 obeticholic acid results in decreased expression of CYP1A2 mRNA CTD PMID:35267068 Cyp1a2 Rat obeticholic acid multiple interactions ISO Cyp1a2 (Mus musculus) 6480464 [Dietary Fats co-treated with obeticholic acid] results in decreased expression of CYP1A2 mRNA and [Dietary Fats co-treated with obeticholic acid] results in decreased expression of CYP1A2 protein CTD PMID:35267068 Cyp1a2 Rat obeticholic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 obeticholic acid results in decreased activity of CYP1A2 protein CTD PMID:27939613 Cyp1a2 Rat obeticholic acid decreases expression ISO CYP1A2 (Homo sapiens) 6480464 obeticholic acid results in decreased expression of CYP1A2 mRNA CTD PMID:27939613 Cyp1a2 Rat ochratoxin A increases expression ISO CYP1A2 (Homo sapiens) 6480464 ochratoxin A results in increased expression of CYP1A2 mRNA and ochratoxin A results in increased expression of CYP1A2 protein CTD PMID:21834667 and PMID:30291945 Cyp1a2 Rat ochratoxin A increases expression ISO Cyp1a2 (Mus musculus) 6480464 ochratoxin A results in increased expression of CYP1A2 mRNA and ochratoxin A results in increased expression of CYP1A2 protein CTD PMID:30291945 Cyp1a2 Rat ochratoxin A increases response to substance ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased susceptibility to ochratoxin A CTD PMID:11189750 more ... Cyp1a2 Rat Octachlorostyrene increases activity ISO Cyp1a2 (Mus musculus) 6480464 octachlorostyrene results in increased activity of CYP1A2 protein CTD PMID:19525444 Cyp1a2 Rat Octachlorostyrene increases expression ISO Cyp1a2 (Mus musculus) 6480464 octachlorostyrene results in increased expression of CYP1A2 mRNA CTD PMID:19525444 Cyp1a2 Rat octamethylcyclotetrasiloxane multiple interactions EXP 6480464 octamethylcyclotetrasiloxane results in decreased expression of and results in increased activity of CYP1A2 protein CTD PMID:36100151 Cyp1a2 Rat ofloxacin multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 [Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline] CTD PMID:11408986 Cyp1a2 Rat okadaic acid multiple interactions EXP 6480464 CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Okadaic Acid CTD PMID:26374342 Cyp1a2 Rat okadaic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Okadaic Acid CTD PMID:26374342 Cyp1a2 Rat okanin decreases activity ISO CYP1A2 (Homo sapiens) 6480464 okanin results in decreased activity of CYP1A2 protein CTD PMID:29753067 Cyp1a2 Rat olanzapine affects metabolic processing ISO CYP1A2 (Homo sapiens) 6480464 CYP1A2 protein affects the metabolism of olanzapine CTD PMID:15545309 and PMID:15883149 Cyp1a2 Rat olanzapine multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Fluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of olanzapine] CTD PMID:15545309 Cyp1a2 Rat oleanolic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Oleanolic Acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin] CTD PMID:15043991 Cyp1a2 Rat oleanolic acid decreases expression ISO Cyp1a2 (Mus musculus) 6480464 Oleanolic Acid results in decreased expression of CYP1A2 mRNA CTD PMID:23948738 Cyp1a2 Rat oleanolic acid decreases expression EXP 6480464 Oleanolic Acid results in decreased expression of CYP1A2 mRNA CTD PMID:18706400 Cyp1a2 Rat oleanolic acid decreases activity ISO CYP1A2 (Homo sapiens) 6480464 Oleanolic Acid results in decreased activity of CYP1A2 protein CTD PMID:15043991 Cyp1a2 Rat oleic acid decreases expression ISO CYP1A2 (Homo sapiens) 6480464 Oleic Acid results in decreased expression of CYP1A2 mRNA CTD PMID:30611723 Cyp1a2 Rat oleic acid multiple interactions ISO CYP1A2 (Homo sapiens) 6480464 Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA]