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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2459
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:16514
Term: 4',5,7-trihydroxy-3'-methoxyflavone
Definition: The 3'-O-methyl derivative of luteolin.
Chemical ID: MESH:C007054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2multiple interactionsISOCYP1A2 (Homo sapiens)6480464CTDchrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]PMID:20553787
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