GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a2 | increases activity | EXP | | 6480464 | CTD | Hexachlorocyclohexane results in increased activity of CYP1A2 protein | PMID:12842176 PMID:16641539 | Cyp1a2 | increases expression | EXP | | 6480464 | CTD | Hexachlorocyclohexane results in increased expression of CYP1A2 mRNA; Hexachlorocyclohexane results in increased expression of CYP1A2 protein | PMID:12842176 PMID:17919674 PMID:17984293 PMID:18486174 PMID:23927878 PMID:25572523 | Cyp1a2 | multiple interactions | EXP | | 6480464 | CTD | Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein]; Phenobarbital promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein] | PMID:18486174 | |
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