A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID:
MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,7-dinitrofluorene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; [Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein; [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] which results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline; Acetaminophen inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Aminoquinolines inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Benzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Cisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; CYP1A2 protein binds to and affects the abundance of Tetrachlorodibenzodioxin; Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Ditiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Doxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; ellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; furafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Hemin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]; Hydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Levodopa inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]; Orphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Tacrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Tetrachlorodibenzodioxin inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]; Tetrachlorodibenzodioxin promotes the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein; tin mesoporphyrin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]; Tolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Tetrachlorodibenzodioxin results in increased expression of CYP1A2; Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA; Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein
[CYP1A2 protein affects the abundance of Tetrachlorodibenzodioxin] inhibits the reaction [CYP1A1 protein results in increased metabolism of Tetrachlorodibenzodioxin]; [Mercury co-treated with methylmercuric chloride] inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP1A2 mRNA; [Tetrachlorodibenzodioxin co-treated with AHR protein] results in increased expression of CYP1A2 mRNA; [Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; [Tetrachlorodibenzodioxin results in increased localization of AHR protein] which results in increased expression of CYP1A2 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of CYP1A2 mRNA; AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP1A2 mRNA]; ammonium metavanadate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; ARNT affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]; arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; CYP1A2 protein affects the abundance of and affects the susceptibility to Tetrachlorodibenzodioxin; CYP1A2 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Iron-Dextran Complex inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; methylmercuric chloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; methylmercuric chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; methylmercuric chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]; monomethylmonothioarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; monomethylmonothioarsonic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]; sodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Butyrates results in increased expression of CYP1A2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [trichostatin A results in increased expression of CYP1A2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A2 gene]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A2 promoter]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]
1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,3,3',4,4',5-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,3,3',4,4'-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2,7-dinitrofluorene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; 3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; 4-nitroquinolone-1-oxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A2 mRNA; [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; [Tetrachlorodibenzodioxin co-treated with AHR mRNA] affects the expression of CYP1A2 mRNA; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA; AHR protein polymorphism affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Aminoquinolines inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]; Arsenic Trioxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Benzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Chir 99021 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Cisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Ditiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Doxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; ellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; flavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; furafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; galangin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Hydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Isoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Melphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methotrexate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]; Mycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; NCX 4040 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Nitrofurantoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Oxygen deficiency affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Papaverine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Perhexiline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Plant Extracts inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; pyrazolanthrone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; S-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; sodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Tacrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; tangeretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A2 enhancer]; Tetrachlorodibenzodioxin promotes the reaction [Biological Factors results in increased expression of CYP1A2 mRNA]; Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein; tin mesoporphyrin inhibits the reaction [sodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]; Tolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Triiodothyronine affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]; Triiodothyronine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]; Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
