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Gene: CYP1A1 (cytochrome P450 family 1 subfamily A member 1) Homo sapiens
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Symbol: CYP1A1
Name: cytochrome P450 family 1 subfamily A member 1
Description: Exhibits arachidonic acid monooxygenase activity; steroid hydroxylase activity; and vitamin D 24-hydroxylase activity. Involved in several processes, including cellular hormone metabolic process; fatty acid metabolic process; and lipid hydroxylation. Predicted to localize to the mitochondrial inner membrane. Implicated in several diseases, including autoimmune hypersensitivity disease (multiple); bone inflammation disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Biomarker of endometriosis; renal cell carcinoma; and urinary bladder cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AHH; AHRR; aryl hydrocarbon hydroxylase; CP11; CYP1; CYPIA1; cytochrome P1-450, dioxin-inducible; cytochrome P450 1A1; cytochrome P450 form 6; cytochrome P450, family 1, subfamily A, polypeptide 1; cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1; cytochrome P450-C; cytochrome P450-P1; flavoprotein-linked monooxygenase; hydroperoxy icosatetraenoate dehydratase; P1-450; P450-C; P450DX; xenobiotic monooxygenase
Orthologs:
Mus musculus (house mouse) : Cyp1a1 (cytochrome P450, family 1, subfamily a, polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp1a1 (cytochrome P450, family 1, subfamily a, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102010850 (cytochrome P450 1A1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100976184 (cytochrome P450 1A1)
Canis lupus familiaris (dog) : CYP1A1 (cytochrome P450 family 1 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969148 (cytochrome P450 1A1)
Sus scrofa (pig) : CYP1A1 (cytochrome P450 1A1)
Chlorocebus sabaeus (green monkey) : CYP1A1 (cytochrome P450 family 1 subfamily A member 1)
Heterocephalus glaber (naked mole-rat) : LOC101707509 (cytochrome P450 1A1)
more info ...
Related Pseudogenes: CYP1D1P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1574,719,542 - 74,725,536 (-)Ensembl
GRCh381574,719,542 - 74,725,528 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371575,011,883 - 75,017,951 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,798,943 - 72,804,930 (-)NCBINCBI36hg18NCBI36
Build 341572,798,942 - 72,804,930NCBI
Celera1551,961,906 - 51,967,900 (-)NCBI
Cytogenetic Map15q24.1NCBI
HuRef1551,809,772 - 51,815,766 (-)NCBIHuRef
CHM1_11575,130,208 - 75,136,276 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model