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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2459
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:82503
Term: 6-Nitrobenzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene that has formula C20H11NO2.
Chemical ID: MESH:C034699
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2increases expressionISOCYP1A2 (Homo sapiens)6480464CTD6-nitrobenzo(a)pyrene results in increased expression of CYP1A2 mRNAPMID:12107646
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