CYP1A2 (cytochrome P450 family 1 subfamily A member 2) - Rat Genome Database

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Gene: CYP1A2 (cytochrome P450 family 1 subfamily A member 2) Canis lupus familiaris
Analyze
Symbol: CYP1A2
Name: cytochrome P450 family 1 subfamily A member 2
RGD ID: 12053109
Description: ENCODES a protein that exhibits caffeine oxidase activity (ortholog); demethylase activity (ortholog); enzyme binding (ortholog); INVOLVED IN alkaloid metabolic process (ortholog); cellular aromatic compound metabolic process (ortholog); cellular respiration (ortholog); PARTICIPATES IN axitinib pharmacokinetics pathway; caffeine pharmacokinetics pathway; clomipramine pharmacokinetics pathway; ASSOCIATED WITH Phenacetin O-Deethylase, Deficiency of; acute kidney failure (ortholog); acute lymphoblastic leukemia (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); INTERACTS WITH clofibrate; phenacetin; phenobarbital
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Cholesterol 25-hydroxylase; CYPIA2; cytochrome P450 1A2; cytochrome P450, family 1, subfamily A, polypeptide 2; Cytochrome P450-D2; Cytochrome-P450-1A2; DAH2; hydroperoxy icosatetraenoate dehydratase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,818,400 - 37,824,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,799,140 - 37,824,135 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,751,388 - 37,757,086 (+)NCBI
ROS_Cfam_1.03038,023,809 - 38,029,593 (+)NCBI
ROS_Cfam_1.0 Ensembl3038,023,809 - 38,029,586 (+)Ensembl
UMICH_Zoey_3.13037,976,275 - 37,981,991 (+)NCBI
UNSW_CanFamBas_1.03038,002,364 - 38,008,076 (+)NCBI
UU_Cfam_GSD_1.03038,258,389 - 38,264,108 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
'de novo' CTP biosynthetic process  (IEA)
alkaloid metabolic process  (ISO)
arachidonic acid metabolic process  (IEA)
cellular aromatic compound metabolic process  (ISO)
cellular respiration  (ISO)
cellular response to cadmium ion  (ISO)
cellular response to copper ion  (ISO)
cholesterol metabolic process  (IEA)
dibenzo-p-dioxin metabolic process  (ISO)
estrogen metabolic process  (ISS)
fatty acid metabolic process  (IEA)
heterocycle metabolic process  (ISO)
hydrogen peroxide biosynthetic process  (ISO)
L-proline biosynthetic process  (IEA)
leucine biosynthetic process  (IEA)
lipid metabolic process  (IEA)
lung development  (ISO)
monocarboxylic acid metabolic process  (ISO)
monoterpenoid metabolic process  (ISO)
oxidative demethylation  (ISO)
oxidative phosphorylation  (IEA)
pantothenate biosynthetic process  (IEA)
pectin catabolic process  (IEA)
phospholipid metabolic process  (IEA)
porphyrin-containing compound metabolic process  (ISO)
post-embryonic development  (ISO)
protein glycosylation  (IEA)
protein ubiquitination  (IEA)
regulation of gene expression  (ISO)
response to estradiol  (ISO)
response to immobilization stress  (ISO)
response to lipopolysaccharide  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to xenobiotic stimulus  (ISO)
retinol metabolic process  (IEA,ISS)
steroid catabolic process  (ISO)
steroid metabolic process  (IEA)
thiamine diphosphate biosynthetic process  (IEA)
toxin biosynthetic process  (ISO)
toxin metabolic process  (ISO)
UMP salvage  (IEA)
urea catabolic process  (IEA)
xenobiotic catabolic process  (ISO)
xenobiotic metabolic process  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:2122230   PMID:15564884   PMID:15742977   PMID:16882764   PMID:19356037   PMID:21219354   PMID:22074769  


Genomics

Comparative Map Data
CYP1A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,818,400 - 37,824,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,799,140 - 37,824,135 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3037,751,388 - 37,757,086 (+)NCBI
ROS_Cfam_1.03038,023,809 - 38,029,593 (+)NCBI
ROS_Cfam_1.0 Ensembl3038,023,809 - 38,029,586 (+)Ensembl
UMICH_Zoey_3.13037,976,275 - 37,981,991 (+)NCBI
UNSW_CanFamBas_1.03038,002,364 - 38,008,076 (+)NCBI
UU_Cfam_GSD_1.03038,258,389 - 38,264,108 (+)NCBI
CYP1A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381574,748,845 - 74,756,607 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1574,748,845 - 74,756,607 (+)EnsemblGRCh38hg38GRCh38
GRCh371575,041,186 - 75,048,948 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,828,237 - 72,835,994 (+)NCBINCBI36hg18NCBI36
Build 341572,828,236 - 72,835,994NCBI
Celera1551,991,217 - 51,998,975 (+)NCBI
Cytogenetic Map15q24.1NCBI
HuRef1551,838,984 - 51,846,743 (+)NCBIHuRef
CHM1_11575,159,686 - 75,167,443 (+)NCBICHM1_1
T2T-CHM13v2.01572,618,749 - 72,626,513 (+)NCBI
Cyp1a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,584,220 - 57,590,938 (-)NCBIGRCm39mm39
GRCm39 Ensembl957,584,220 - 57,590,986 (-)Ensembl
GRCm38957,676,937 - 57,683,655 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl957,676,937 - 57,683,703 (-)EnsemblGRCm38mm10GRCm38
MGSCv37957,524,744 - 57,531,462 (-)NCBIGRCm37mm9NCBIm37
MGSCv36957,475,074 - 57,481,792 (-)NCBImm8
Celera954,913,185 - 54,919,903 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.3NCBI
Cyp1a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2858,075,367 - 58,082,255 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl858,075,367 - 58,082,312 (-)Ensembl
Rnor_6.0862,451,360 - 62,458,244 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,451,329 - 62,458,301 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0862,228,271 - 62,235,203 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4861,439,062 - 61,447,861 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1861,458,143 - 61,464,586 (-)NCBI
Celera857,541,217 - 57,547,956 (-)NCBICelera
Cytogenetic Map8q24NCBI
LOC102010322
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,165,106 - 3,171,942 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554503,165,107 - 3,171,894 (-)NCBIChiLan1.0ChiLan1.0
CYP1A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11573,311,720 - 73,319,447 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1573,311,720 - 73,319,447 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01553,692,877 - 53,699,279 (+)NCBIMhudiblu_PPA_v0panPan3
LOC101969421
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640115,856,553 - 115,861,413 (+)NCBI
SpeTri2.0NW_00493647133,704,616 - 33,709,455 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP1A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl758,779,475 - 58,786,100 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1758,779,529 - 58,786,155 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2763,468,129 - 63,474,724 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP1A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1268,727,996 - 8,733,254 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048132,898,379 - 132,904,792 (+)NCBIVero_WHO_p1.0


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 6 2
Low 5 3 2
Below cutoff 5 5 10 1 1 2 8 8 6 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001008720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014109343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038441745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB094347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB094348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB094349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB159771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB159772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG965165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG965166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG965167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG974425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000039456   ⟹   ENSCAFP00000035314
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3037,818,448 - 37,824,135 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000062929   ⟹   ENSCAFP00000043910
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3037,818,448 - 37,824,078 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000075972   ⟹   ENSCAFP00000051204
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3037,818,448 - 37,824,135 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000087022   ⟹   ENSCAFP00000059348
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3037,799,140 - 37,824,135 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031115   ⟹   ENSCAFP00845024370
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3038,023,809 - 38,029,586 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031200   ⟹   ENSCAFP00845024423
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3038,023,809 - 38,029,535 (+)Ensembl
RefSeq Acc Id: NM_001008720   ⟹   NP_001008720
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13037,818,448 - 37,824,135 (+)NCBI
Dog10K_Boxer_Tasha3037,751,388 - 37,757,086 (+)NCBI
ROS_Cfam_1.03038,023,809 - 38,029,535 (+)NCBI
UMICH_Zoey_3.13037,976,275 - 37,981,991 (+)NCBI
UNSW_CanFamBas_1.03038,002,364 - 38,008,076 (+)NCBI
UU_Cfam_GSD_1.03038,258,389 - 38,264,108 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038441745   ⟹   XP_038297673
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03038,023,817 - 38,029,593 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001008720   ⟸   NM_001008720
- Peptide Label: precursor
- UniProtKB: Q5R2U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000035314   ⟸   ENSCAFT00000039456
RefSeq Acc Id: ENSCAFP00000059348   ⟸   ENSCAFT00000087022
RefSeq Acc Id: ENSCAFP00000043910   ⟸   ENSCAFT00000062929
RefSeq Acc Id: ENSCAFP00000051204   ⟸   ENSCAFT00000075972
RefSeq Acc Id: XP_038297673   ⟸   XM_038441745
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845024370   ⟸   ENSCAFT00845031115
RefSeq Acc Id: ENSCAFP00845024423   ⟸   ENSCAFT00845031200

Promoters
RGD ID:13688585
Promoter ID:EPDNEW_C6654
Type:multiple initiation site
Name:CYP1A2_1
Description:cytochrome P450 family 1 subfamily A member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13037,818,448 - 37,818,508EPDNEW
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
30 37819684 37819685 C G snv Bavarian Hound (BG064), Wolf (WO002_732), Greyhound (GY432), Kunming Dog (KM10), Kunming Dog (KM5), Chinese indigenous dogs (LJ4), Lagotto Romagnolo (LR494), Great Lakes Wolf (SRS661486), Standard Poodle (SRS932143), Wolf (WO003_636), Landseer (ZS14), Australian Cattle dog (AC108), Berger Blanc Suisse (BB011), Bearded Collie (BD016), Bearded Collie (BD085), Bearded Collie (BD093), Bearded Collie (BD098), Beagle (BE020), Cavalier King Charles Spaniel (CK023), German Shepherd (DS043), German Shepherd (DS051), German Shepherd (DS053), Golden Retriever (GR1078), German Shepherd (GS1), German Shepherd (GS2), German Shepherd (GS4), German Shepherd (GS6), German Shepherd (GS7), German Shepherd (GS9), Siberian Husky (KKH2684), Kunming Dog (KM9), Greater Swiss Mountain Dog (SH008), Iranian Wolf (SRS661488), Portuguese Wolf (SRS661492), Spanish Wolf (SRS661495), Shetland Sheepdog (SRS932138), Shetland Sheepdog (SS004), Airedale Terrier (TA001), Tibetan Mastiff (TM7), Weimaraner (WE006), Whippet (WH083), German Wirehaired (GW004)
30 37819691 37819692 G A snv German Wirehaired (GW004), Greyhound (GY432), Siberian Husky (KKH2684), Kunming Dog (KM10), Kunming Dog (KM5), Kunming Dog (KM9), Chinese indigenous dogs (LJ4), Lagotto Romagnolo (LR494), Greater Swiss Mountain Dog (SH008), Great Lakes Wolf (SRS661486), Iranian Wolf (SRS661488), Portuguese Wolf (SRS661492), Spanish Wolf (SRS661495), Shetland Sheepdog (SRS932138), Standard Poodle (SRS932143), Shetland Sheepdog (SS004), Airedale Terrier (TA001), Tibetan Mastiff (TM7), Weimaraner (WE006), Whippet (WH083), Wolf (WO002_732), Wolf (WO003_636), Landseer (ZS14), Tibetan Mastiff (TM5), Alaskan Malamute (AM007), Irish Terrier (IT0390), Irish Terrier (IT221), Jack Russell Terrier (JR0034), Poodle (PL116), Australian Cattle dog (AC108), Berger Blanc Suisse (BB011), Bearded Collie (BD016), Bearded Collie (BD085), Bearded Collie (BD093), Bearded Collie (BD098), Beagle (BE020), Bavarian Hound (BG064), Cavalier King Charles Spaniel (CK023), German Shepherd (DS043), German Shepherd (DS051), German Shepherd (DS053), Golden Retriever (GR1078), German Shepherd (GS1), German Shepherd (GS2), German Shepherd (GS4), German Shepherd (GS6), German Shepherd (GS7), German Shepherd (GS9)
30 37819769 37819770 G A snv Chinese indigenous dogs (YJ7), Chinese indigenous dogs (YJ5), Chinese indigenous dogs (DQ7)
30 37820060 37820061 C T snv Wolf (WO003_636), Great Lakes Wolf (SRS661486), German Shepherd (DS064)
30 37820061 37820062 C T snv West Highland White Terrier (WW362), West Highland White Terrier (WW363), West Highland White Terrier (WW364), West Highland White Terrier (WW558), Alpine Dachsbracke (AD009), American Staffordshire Terrier (AS006), Chinese indigenous dogs (LJ7), Tibetan Mastiff (TM4), West Highland White Terrier (WW64), Bavarian Hound (BG064), Chihuahua (CH019), Cocker Spaniel (CP003), Dachshund (DH0117), Dachshund (DH126), Doberman Pinscher (DO159), Doberman Pinscher (DO242), Doberman Pinscher (DO263), Chinese indigenous dogs (DQ4), Entlebucher Sennenhund (EN261), Entlebucher Sennenhund (EN264), French Bulldog (FB065), Golden Retriever (GR0855), Golden Retriever (GR0859), Golden Retriever (GR0860), Golden Retriever (GR0892), German Wirehaired (GW004), Kromfohrländer (KF042), Kunming Dog (KM1), Kunming Dog (KM10), Kunming Dog (KM2), Kunming Dog (KM4), Kunming Dog (KM5), Kunming Dog (KM6), Kunming Dog (KM7), Kunming Dog (KM8), Labrador Retriever (LA1869), Labrador Retriever (LA2443), Labrador Retriever (LA882), Labrador Retriever (LA900), Leonberger (LB111), Leonberger (LB1919), Chinese indigenous dogs (LJ2), Chinese indigenous dogs (LJ4), Landseer (LN048), Lagotto Romagnolo (LR1030), Lagotto Romagnolo (LR433), Lagotto Romagnolo (LR494), Lagotto Romagnolo (LR538), Lagotto Romagnolo (LR753), Malinois (MA0163), Malinois (MA324), Mixed Breed (MI016), Norwich Terrier (NW062), Norwich Terrier (NW152), Norwich Terrier (NW206), Old English Sheepdog (OS001), Rottweiler (RO2), Rhodesian Ridgeback (RR098), Rhodesian Ridgeback (RR123), Rhodesian Ridgeback (RR224), Sloughi (SG005), Chinese Crested (SRS713815), Black Russian Terrier (SRS833812), Standard Poodle (SRS932143), Tibetan Mastiff (TM6), Weimaraner (WE008), West Highland White Terrier (WW174), West Highland White Terrier (WW361)
30 37820774 37820775 C T snv Alpine Dachsbracke (AD009), Berger Blanc Suisse (BB011), Chihuahua (CH019), Cocker Spaniel (CP003), Dachshund (DH0117), Dachshund (DH126), Doberman Pinscher (DO159), Doberman Pinscher (DO242), Doberman Pinscher (DO263), Chinese indigenous dogs (DQ4), Chinese indigenous dogs (DQ7), Chinese indigenous dogs (DQ8), German Shepherd (DS043), German Shepherd (DS053), German Shepherd (DS064), Entlebucher Sennenhund (EN261), Entlebucher Sennenhund (EN264), French Bulldog (FB065), German Shepherd (GS1), German Shepherd (GS2), German Shepherd (GS6), German Shepherd (GS7), German Wirehaired (GW004), German Hunting Terrier (JT007), Kunming Dog (KM1), Kunming Dog (KM4), Kunming Dog (KM7), Kunming Dog (KM8), Kunming Dog (KM9), Labrador Retriever (LA882), Leonberger (LB1919), Chinese indigenous dogs (LJ2), Chinese indigenous dogs (LJ4), Landseer (LN048), Lagotto Romagnolo (LR433), Lagotto Romagnolo (LR494), Lagotto Romagnolo (LR753), Malinois (MA0163), Malinois (MA152), Mixed Breed (MI016), Norwich Terrier (NW062), Norwich Terrier (NW152), Norwich Terrier (NW206), Old English Sheepdog (OS001), Rottweiler (RO2), Rhodesian Ridgeback (RR098), Rhodesian Ridgeback (RR123), Rhodesian Ridgeback (RR224), Sloughi (SG005), Iranian Wolf (SRS661488), Portuguese Wolf (SRS661492), Spanish Wolf (SRS661495), Chinese Crested (SRS713815), Black Russian Terrier (SRS833812), Alaskan Husky (SY001), Tibetan Mastiff (TM6), Weimaraner (WE006), Weimaraner (WE008), Whippet (WH083), Wolf (WO001_895), Wolf (WO002_732), Wolf (WO003_636), West Highland White Terrier (WW174), West Highland White Terrier (WW362), West Highland White Terrier (WW364), West Highland White Terrier (WW64), Chinese indigenous dogs (YJ5), Chinese indigenous dogs (YJ7), Landseer (ZS14), Pomeranian (ZS14_2), American Staffordshire Terrier (AS006), Border Collie (BC0480), Border Collie (BC272), Border Collie (BC518), Border Collie (BC555), Bearded Collie (BD052), Bearded Collie (BD089), Bearded Collie (BD093), Beagle (BE020), Bavarian Hound (BG064), Basset (BH003), Basenji (BJ001), Basenji (BJ002), Basenji (BJ003), Basenji (BJ004), Basenji (BJ005), Basenji (BJ006), Cavalier King Charles Spaniel (CK006), Chinese indigenous dogs (DQ10), Chinese indigenous dogs (DQ2), Chinese indigenous dogs (DQ3), Chinese indigenous dogs (DQ5), Chinese indigenous dogs (DQ6), German Shepherd/Mixed breed (DS032), German Shepherd/Mixed breed (DS041), German Shepherd/Mixed breed (DS042), German Shepherd (DS051), Elo (EL565), Entlebucher Sennenhund (EN091), Entlebucher Sennenhund (EN154), Entlebucher Sennenhund (EN221), Entlebucher Sennenhund (EN247), Entlebucher Sennenhund (EN262), Entlebucher Sennenhund (EN263), Eurasier (EU008), Eurasier (EU035), French Bulldog (FB046), Golden Retriever (GR0855), Golden Retriever (GR0859), Golden Retriever (GR0860), Golden Retriever (GR0892), Golden Retriever (GR1078), German Shepherd (GS10), German Spitz (GS104), German Shepherd (GS3), German Shepherd (GS4), German Shepherd (GS5), German Shepherd (GS8), German Shepherd (GS9), Greyhound (GY432), Hovawart (HW1706), Jack Russell Terrier (JR0034), Kromfohrländer (KF042), Kunming Dog (KM10), Kunming Dog (KM2), Kunming Dog (KM3), Kunming Dog (KM5), Kunming Dog (KM6), Labrador Retriever (LA1869), Labrador Retriever (LA2382), Labrador Retriever (LA2443), Labrador Retriever (LA900), Leonberger (LB111), Chinese indigenous dogs (LJ1), Chinese indigenous dogs (LJ3), Chinese indigenous dogs (LJ5), Chinese indigenous dogs (LJ6), Chinese indigenous dogs (LJ7), Chinese indigenous dogs (LJ8), Chinese indigenous dogs (LJ9), Border Collie (LN47), Lagotto Romagnolo (LR1030), Lagotto Romagnolo (LR390), Lagotto Romagnolo (LR538), Malinois (MA008), Malinois (MA094), Malinois (MA142), Malinois (MA324), Norwich Terrier (NW255), Spanish Water Dog (PE002), Poodle (PL116), Sloughi (SG006), Sloughi (SG008), Cavalier King Charles Spaniel (SID00101), Saluki (SL006), Great Lakes Wolf (SRS661486), Pembroke Welsh Corgi (SRS732551), Standard Poodle (SRS932143), Border Terrier (SRS932144), Siberian Husky (SY046), Tibetan Mastiff (TM10), Tibetan Mastiff (TM3), Tibetan Mastiff (TM4), Tibetan Mastiff (TM5), Tibetan Mastiff (TM7), Tibetan Mastiff (TM8), Tibetan Mastiff (TM9), West Highland White Terrier (WW361), West Highland White Terrier (WW363), West Highland White Terrier (WW558), Chinese indigenous dogs (YJ1), Chinese indigenous dogs (YJ2), Chinese indigenous dogs (YJ3), Chinese indigenous dogs (YJ6)
30 37821271 37821272 C T snv Dachshund (DH126), Dachshund (DH0117)
30 37821630 37821631 G A snv German Hunting Terrier (JT007)
30 37823914 37823915 C A snv Lagotto Romagnolo (LR1030), Doberman Pinscher (DO159), Doberman Pinscher (DO263), Bullterrier (BT012), American Staffordshire Terrier (AS006), Lagotto Romagnolo (LR390), French Bulldog (FB046)
30 37823974 37823975 G A snv American Staffordshire Terrier (AS006), French Bulldog (FB046)
30 37823987 37823988 T G snv Wolf (WO002_732), Wolf (WO001_895)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017941 Ensembl
  ENSCAFG00030010701 UniProtKB/TrEMBL
  ENSCAFG00040019909 UniProtKB/TrEMBL
  ENSCAFG00845017565 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030017255.1 UniProtKB/TrEMBL
  ENSCAFP00030017298.1 UniProtKB/TrEMBL
  ENSCAFP00030017348.1 UniProtKB/TrEMBL
  ENSCAFP00030017409.1 UniProtKB/TrEMBL
  ENSCAFP00030017478.1 UniProtKB/TrEMBL
  ENSCAFP00030017567.1 UniProtKB/TrEMBL
  ENSCAFP00030017605.1 UniProtKB/TrEMBL
  ENSCAFP00030017652.1 UniProtKB/TrEMBL
  ENSCAFP00030017726.1 UniProtKB/TrEMBL
  ENSCAFP00030017792.1 UniProtKB/TrEMBL
  ENSCAFP00040032100 UniProtKB/TrEMBL
  ENSCAFP00845024370.1 UniProtKB/TrEMBL
  ENSCAFP00845024423 ENTREZGENE
  ENSCAFP00845024423.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030019784.1 UniProtKB/TrEMBL
  ENSCAFT00030019837.1 UniProtKB/TrEMBL
  ENSCAFT00030019905.1 UniProtKB/TrEMBL
  ENSCAFT00030019976.1 UniProtKB/TrEMBL
  ENSCAFT00030020047.1 UniProtKB/TrEMBL
  ENSCAFT00030020143.1 UniProtKB/TrEMBL
  ENSCAFT00030020190.1 UniProtKB/TrEMBL
  ENSCAFT00030020242.1 UniProtKB/TrEMBL
  ENSCAFT00030020322.1 UniProtKB/TrEMBL
  ENSCAFT00030020396.1 UniProtKB/TrEMBL
  ENSCAFT00040036860 UniProtKB/TrEMBL
  ENSCAFT00845031115.1 UniProtKB/TrEMBL
  ENSCAFT00845031200 ENTREZGENE
  ENSCAFT00845031200.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I_CYP1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:494010 UniProtKB/TrEMBL
NCBI Gene CYP1A2 ENTREZGENE
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EP450ICYP1A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0MVP8_CANLF UniProtKB/TrEMBL
  A0A8C0MVZ9_CANLF UniProtKB/TrEMBL
  A0A8C0MW85_CANLF UniProtKB/TrEMBL
  A0A8C0N095_CANLF UniProtKB/TrEMBL
  A0A8C0N0G7_CANLF UniProtKB/TrEMBL
  A0A8C0N4G5_CANLF UniProtKB/TrEMBL
  A0A8C0N8P1_CANLF UniProtKB/TrEMBL
  A0A8C0RHF9_CANLF UniProtKB/TrEMBL
  A0A8C0T5R7_CANLF UniProtKB/TrEMBL
  A0A8I3P112_CANLF UniProtKB/TrEMBL
  A0A8I3RZY7_CANLF UniProtKB/TrEMBL
  CP1A2_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
  Q5DWS1_CANLF UniProtKB/TrEMBL
  Q5DWS2_CANLF UniProtKB/TrEMBL
  Q5R2U2 ENTREZGENE, UniProtKB/TrEMBL
  X5L1K8_CANLF UniProtKB/TrEMBL
  X5L560_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:50333 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-09 CYP1A2  cytochrome P450 family 1 subfamily A member 2    cytochrome P450, family 1, subfamily A, polypeptide 2  Symbol and/or name change 5135510 APPROVED