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Gene: Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2) Mus musculus
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Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Description: Exhibits oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including cellular response to cadmium ion; dibenzo-p-dioxin metabolic process; and hydrogen peroxide biosynthetic process. Predicted to localize to the intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Is expressed in liver. Orthologous to human CYP1A2 (cytochrome P450 family 1 subfamily A member 2); PARTICIPATES IN caffeine pharmacokinetics pathway; clomipramine pharmacokinetics pathway; clopidogrel pharmacodynamics pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-artemisinin; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aromatic compound inducible; cholesterol 25-hydroxylase; CP12; Cyp1a1; CYPIA2; cytochrome P450 1A2; cytochrome P450 family 1 subfamily a polypeptide 1; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450-P2; cytochrome P450-P3; hydroperoxy icosatetraenoate dehydratase; P450-3
Orthologs:
Homo sapiens (human) : CYP1A2 (cytochrome P450 family 1 subfamily A member 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102010322 (cytochrome P450 1A2)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100975837 (cytochrome P450 1A2)
Canis lupus familiaris (dog) : CYP1A2 (cytochrome P450 family 1 subfamily A member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969421 (cytochrome P450 1A2)
Sus scrofa (pig) : CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38957,676,937 - 57,683,655 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37957,524,744 - 57,531,462 (-)NCBIGRCm37mm9NCBIm37
MGSCv36957,475,074 - 57,481,792 (-)NCBImm8
Celera954,913,185 - 54,919,903 (-)NCBICelera
Cytogenetic Map9 BNCBI
cM Map931.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations