Alc32 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Alc32 (Alcohol consumption QTL 32) Rattus norvegicus

Symbol: Alc32
Name: Alcohol consumption QTL 32
RGD ID: 8693654
Trait: drinking behavior trait   (VT:0001422)    
Measurement Type: calculated ethanol drink intake rate   (CMO:0001615)    
LOD Score: 2.0
P Value: 0.755
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2888,612,425 - 107,550,209RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0895,319,530 - 115,625,029RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0894,820,292 - 114,983,859RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4892,944,722 - 112,111,932RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: BXH/Ipcv HXB/Ipcv 



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method
scale  (IDA)

Vertebrate Trait

Rat Strain
BXH/Ipcv  (IEA)
HXB/Ipcv  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Is the Alcohol Deprivation Effect Genetically Mediated? Studies with HXB/BXH Recombinant Inbred Rat Strains. Vanderlinden LA, etal., Alcohol Clin Exp Res. 2014 Jun 24. doi: 10.1111/acer.12471.

Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (rs107402384)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2888,612,425 - 88,612,425RGD
Rnor_6.0895,319,530 - 95,319,530RGD
Celera888,189,103 - 88,189,103RGD
Peak: (rs65015946)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2898,028,169 - 98,028,169RGD
Rnor_6.08105,330,342 - 105,330,342RGD
Celera897,460,928 - 97,460,928RGD
Flank 2: (rs105497894)
Rat AssemblyChrPosition (strand)Source
mRatBN7.28107,550,209 - 107,550,209RGD
Rnor_6.08115,625,029 - 115,625,029RGD
Celera8106,862,102 - 106,862,102RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method: rats were given 10% EtOH for 1 week, then for 7 weeks they were given 2-bottle choice of water and EtOH followed by 2 week period of only water (alcohol deprivation); then 2 weeks of 2-bottle choice of water and EtOH followed by second 2 weeks of alcohol deprivation then 2 weeks of 2-bottle choice of water and EtOH followed by third 2 weeks of alcohol deprivation and 1 week of 2-bottle choice of water and EtOH 8663441
qtl_general water and alcohol consumption were measured by weight 8663441
qtl_general alcohol deprivation effect (ADE) was calculated as the amount of alcohol consumed (g/kg) during 24 hrs after deprivation minus average daily amount consumed in the week before deprivation period 8663441
qtl_general this QTL correlates to week 7 pre-ADE alcohol consumption 8663441
qtl_general software used: ANOVA 8663441
qtl_general number of animals used: 70-100 days old males from HXB/BXH RI strains and the parental BN-Lx/CubPrin, SHR/OlaIpcvPrin 8663441
qtl_general spans 94.8-114.8 Mb 8663441