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Gene: Pts (6-pyruvoyl-tetrahydropterin synthase) Rattus norvegicus
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Symbol: Pts
Name: 6-pyruvoyl-tetrahydropterin synthase
Description: Exhibits 6-pyruvoyltetrahydropterin synthase activity. Predicted to be involved in tetrahydrobiopterin biosynthetic process. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in Bh4-deficient hyperphenylalaninemia A and phenylketonuria. Orthologous to human PTS (6-pyruvoyltetrahydropterin synthase); PARTICIPATES IN dopa responsive dystonia pathway; Segawa syndrome pathway; folate metabolic pathway; INTERACTS WITH ammonium chloride; bisphenol A; cobalt dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; PTP synthase; PTPS
Orthologs:
Homo sapiens (human) : PTS (6-pyruvoyltetrahydropterin synthase)  HGNC  Alliance
Mus musculus (house mouse) : Pts (6-pyruvoyl-tetrahydropterin synthase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pts (6-pyruvoyltetrahydropterin synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : PTS (6-pyruvoyltetrahydropterin synthase)
Canis lupus familiaris (dog) : PTS (6-pyruvoyltetrahydropterin synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pts (6-pyruvoyltetrahydropterin synthase)
Sus scrofa (pig) : PTS (6-pyruvoyltetrahydropterin synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0854,954,261 - 54,961,271 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0853,551,584 - 53,558,594 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4853,880,701 - 53,887,711 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1853,899,754 - 53,906,765 (-)NCBI
Celera850,419,474 - 50,426,475 (-)NCBICelera
Cytogenetic Map8q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pts
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68367
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.