Gene: Cyp19a1 (cytochrome P450, family 19, subfamily a, polypeptide 1) Rattus norvegicus
Analyze
Symbol: Cyp19a1
Name: cytochrome P450, family 19, subfamily a, polypeptide 1
Description: ENCODES a protein that exhibits aromatase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding (ortholog); INVOLVED IN adrenal gland development; androgen metabolic process; bile acid metabolic process; PARTICIPATES IN aromatase inhibitor pathway; estradiol biosynthetic pathway; steroid hormone biosynthetic pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; Diabetic Nephropathies; endometriosis; FOUND IN axon terminus; cytoplasm; cytosol; INTERACTS WITH (+)-catechin; (2-trans,6-trans)-farnesol; (S)-naringenin
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aromatase; Cyp19; Cyp19a; CYPXIX; cytochrome P-450AROM; cytochrome P450 19 aromatase; cytochrome P450 19A1; cytochrome P450 19A1-like; cytochrome P450 family 19 subfamily a; cytochrome P450, 19, aromatase; cytochrome P450, subfamily 19; estrogen synthase; estrogen synthetase; LOC100359906; P-450AROM; p450arom
Orthologs:
Homo sapiens (human) : CYP19A1 (cytochrome P450 family 19 subfamily A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp19a1 (cytochrome P450, family 19, subfamily a, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102023780 (aromatase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100984744 (aromatase)
Canis lupus familiaris (dog) : CYP19A1 (cytochrome P450 family 19 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101954950 (aromatase)
Sus scrofa (pig) : CYP19A2 (cytochrome P450 19A2)
more info ...
Is Marker For: QTLs:   GLUCO126_H  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0858,744,849 - 58,772,408 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0857,321,085 - 57,348,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.1857,671,013 - 57,691,109 (-)NCBI
Celera854,044,272 - 54,071,684 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp19a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2457
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE