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Gene: Anxa2 (annexin A2) Rattus norvegicus
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Symbol: Anxa2
Name: annexin A2
Description: Exhibits Rab GTPase binding activity; bone sialoprotein binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including positive regulation of fibroblast proliferation; protein localization to plasma membrane; and response to thyroid hormone. Localizes to several cellular components, including the macropinosome; membrane raft; and ruffle. Biomarker of hyperthyroidism; hypothyroidism; and renal cell carcinoma. Human ortholog(s) of this gene implicated in osteonecrosis. Orthologous to several human genes including ANXA2 (annexin A2); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: annexin 2; annexin II; annexin-2; ANX2; calpactin I heavy chain; calpactin-1 heavy chain; chromobindin-8; lipocortin II; p36; PAP-IV; placental anticoagulant protein IV; protein I
Orthologs:
Homo sapiens (human) : ANXA2 (annexin A2)  HGNC  Alliance
Mus musculus (house mouse) : Anxa2 (annexin A2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Anxa2 (annexin A2)
Pan paniscus (bonobo/pygmy chimpanzee) : ANXA2 (annexin A2)
Canis lupus familiaris (dog) : ANXA2 (annexin A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Anxa2 (annexin A2)
Sus scrofa (pig) : ANXA2 (annexin A2)
Chlorocebus sabaeus (African green monkey) : ANXA2 (annexin A2)
Heterocephalus glaber (naked mole-rat) : Anxa2 (annexin A2)
more info ...
Related Pseudogenes: Anxa2-ps1  
Allele / Splice: Anxa2-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0875,687,134 - 75,723,589 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl875,687,100 - 75,723,594 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0880,014,390 - 80,050,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4873,897,618 - 73,934,041 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1873,916,671 - 73,953,094 (+)NCBI
Celera871,583,756 - 71,620,002 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Anxa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621170
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.