L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)

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Gene: L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2) Rattus norvegicus

Analyze

Symbol:

L3mbtl2

Name:

L3MBTL histone methyl-lysine binding protein 2

RGD ID:

1308569

Description:

Predicted to have methylated histone binding activity and promoter-specific chromatin binding activity. Predicted to be involved in several processes, including ectoderm development; negative regulation of transcription, DNA-templated; and regulation of histone modification. Predicted to localize to nucleus. Orthologous to human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; flutamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

l(3)mbt-like 2 (Drosophila); l(3)mbt-like 2 protein; l(3)mbt-like protein 2; L3MBTL2 polycomb repressive complex 1 subunit; lethal(3)malignant brain tumor-like 2 protein; lethal(3)malignant brain tumor-like protein 2; LOC300320; MGC124862

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	7	122,896,860 - 122,918,025 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	122,896,871 - 122,918,036 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	122,871,375 - 122,892,521 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,016,773 - 120,037,852 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	120,050,975 - 120,071,944 (+)	NCBI
Celera	7	109,505,411 - 109,526,484 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

medulloblastoma (ISO)

nephronophthisis-like nephropathy 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

choline (ISO)

ciguatoxin CTX1B (ISO)

cylindrospermopsin (ISO)

dexamethasone (ISO)

flutamide (EXP)

folic acid (ISO)

indometacin (ISO)

L-methionine (ISO)

methapyrilene (ISO)

nefazodone (EXP)

paracetamol (ISO)

pirinixic acid (ISO)

thioacetamide (EXP)

trichostatin A (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

ectoderm development (ISO)

negative regulation of gene expression (ISO)

negative regulation of histone acetylation (ISO)

negative regulation of transcription, DNA-templated (IBA)

positive regulation of histone methylation (ISO)

stem cell differentiation (ISO)

stem cell proliferation (ISO)

Cellular Component

nucleus (IBA,ISO)

Molecular Function

chromatin binding (IBA)

histone binding (IBA,ISO)

methylated histone binding (IBA,ISO,ISS)

promoter-specific chromatin binding (ISO)

protein binding (ISO)

zinc ion binding (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	MGD data from the GO Consortium
4.	RGD automated data pipeline
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:14597177	PMID:17540172	PMID:19233876	PMID:22770845

Genomics

Comparative Map Data

L3mbtl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	7	122,896,860 - 122,918,025 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	122,896,871 - 122,918,036 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	122,871,375 - 122,892,521 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	120,016,773 - 120,037,852 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	120,050,975 - 120,071,944 (+)	NCBI
Celera	7	109,505,411 - 109,526,484 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

L3MBTL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	22	41,205,282 - 41,231,271 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	22	41,205,192 - 41,231,271 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	22	41,601,312 - 41,627,276 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	39,931,259 - 39,957,221 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	22	39,925,812 - 39,951,774	NCBI
Celera	22	25,407,662 - 25,433,655 (+)	NCBI
Cytogenetic Map	22	q13.2	NCBI
HuRef	22	24,565,907 - 24,591,739 (+)	NCBI		HuRef
CHM1_1	22	41,560,987 - 41,586,967 (+)	NCBI		CHM1_1

L3mbtl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	81,548,090 - 81,572,516 (+)	NCBI	GRCm39		mm39
GRCm38	15	81,663,889 - 81,688,315 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	81,663,889 - 81,688,315 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	81,494,366 - 81,518,735 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	15	81,491,191 - 81,515,560 (+)	NCBI			mm8
Celera	15	83,782,718 - 83,807,411 (+)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI

L3mbtl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	26,831,066 - 26,851,859 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	26,831,065 - 26,847,638 (+)	NCBI	ChiLan1.0	ChiLan1.0

L3MBTL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	22	40,193,492 - 40,218,925 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	40,193,492 - 40,218,925 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	22	22,102,348 - 22,128,351 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

L3MBTL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	10	24,002,183 - 24,021,753 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	10	24,000,008 - 24,021,883 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

L3mbtl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936492	642,434 - 666,402 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

L3MBTL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	7,253,644 - 7,277,576 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	7,257,806 - 7,277,633 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	4,509,562 - 4,530,093 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

L3MBTL2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	19	23,750,212 - 23,776,947 (+)	Ensembl
ChlSab1.1	19	23,749,894 - 23,774,749 (+)	NCBI

L3mbtl2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624752	7,291,888 - 7,309,379 (-)	NCBI

Position Markers

RH130689

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	7	122,916,989 - 122,917,879	NCBI	Rnor6.0
Rnor_5.0	7	122,891,485 - 122,892,375	UniSTS	Rnor5.0
RGSC_v3.4	7	120,036,821 - 120,037,711	UniSTS	RGSC3.4
Celera	7	109,525,453 - 109,526,343	UniSTS
Cytogenetic Map	7	q34	UniSTS
RH 3.4 Map	7	880.6	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	2920071	124838025	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	48118835	128611831	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	50704769	128085642	Rat
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	51251919	145729302	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	55072862	123602998	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	55072862	123602998	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	55072862	123602998	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	71448715	145729302	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	77428105	127748511	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	81645773	140745067	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	85595369	130595369	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	85595369	130595369	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	88365265	133365265	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	88365265	134673427	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	91018361	136018361	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	91832949	145158140	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	91832949	145158140	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	93726906	138726906	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	93726906	138726906	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	96630946	141630946	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	100028953	145729302	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	100160423	140335001	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	100192194	145192194	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	103815550	126525386	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	103867802	126080176	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	106564316	145729302	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	111519266	143965591	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	112429186	126525386	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	114825174	145729302	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	115922628	145729302	Rat
631663	Bw6	Body weight QTL 6	3.4		body mass (VT:0001259)	body weight (CMO:0000012)	7	120746024	145692398	Rat
1300112	Bp183	Blood pressure QTL 183	3.51		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	121654760	145729302	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	121986439	143965591	Rat
1357339	Stl14	Serum triglyceride level QTL 14	3.45	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	122421276	143965415	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	156
Count of miRNA genes:	120
Interacting mature miRNAs:	136
Transcripts:	ENSRNOT00000034998
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	30	55	39	19	39			74	35	41	11
Low		13	2	2		2	8	11					8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001033695	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008765711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07058540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01051853	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC101865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000034998 ⟹ ENSRNOP00000031908

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	122,896,871 - 122,918,036 (+)	Ensembl

RefSeq Acc Id:

NM_001033695 ⟹ NP_001028867

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	122,896,942 - 122,918,020 (+)	NCBI
Rnor_5.0	7	122,871,375 - 122,892,521 (+)	NCBI
RGSC_v3.4	7	120,016,773 - 120,037,852 (+)	RGD
Celera	7	109,505,411 - 109,526,484 (+)	RGD

Sequence:

show sequence

GGAAATTGAATTTGGTATCATGGAGAAGCCGCGGGGCACTGAGGAGACGCCATCTTCAGAGCCA
ATGGAAGAGGAGGAAGATGATGACTTGGAACTCTTCGGAGGCTACGATAGCTTCCGGAGTTACA
ACAGCAGTGCGGGCAGTGAGAGCAGCTCCTACTTGGAGGAGTCAAGTGAAGCAGAAAATGAGGA
TCGGGAAGCAGGGGAGCTGCCCACCTCACCTCTGCATCTGTTCAGCTCTGCGAATAACCGCGCC
TTGGATGGCAGTGGTTCTGAGCCAGCTGTCTGTGAGATGTGTGGTATTGTGGGCACCAGAGAAG
CTTTCTTTTCAAAGACCAAGAGGTTCTGCAGTGTCTCATGTTCCAGGAGCTACTCTTCCAACTC
CAAGAAAGCCAGTATCTTGGCTAGACTTCAGGGAAAGCCCCCCACCAAGAAAGCCAAAGTCCTG
CACAAAGCAGCCTGGTCCGCCAAAATTGGAGCCTTCCTCCACGCCCAGGGAACAGGACAGCTAG
CAGATGGGACACCCACAGGACAAGACGCTCTAGTCTTGGGGTTCGACTGGGGGAAGTTCCTGAA
GGATCACAGTTACAAGGCTGCTCCTGTCGGCTGCTTTAAACACGTACCCCTCTATGACCAGTGG
GAGGACGTCATGAAGGGGATGAAGGTAGAAGTCCTCAACAGCGACGCCGTGCTCCCCAGCCGGG
TGTACTGGATCGCCACTGTCATCCAGGCAGCTGGGTACCGGGTACTGCTCCGATATGAAGGCTT
TGAGAATGACGCCAGTCATGACTTCTGGTGCAACCTGGGGACTGTGGACGTCCACCCCATTGGG
TGGTGTGCCATCAACAGCAAGATCCTGGTGCCTCCACGGACCATCCATGCCAAGTTTACTGACT
GGAAGAGCTACCTCATGAAGCGGTTGGTGGGATCCAGGACACTTCCTGCAGATTTCCATATCAA
GATGGTAGAAAGCATGAAGTACCCCTTTCGGCAGGGCATGCGCTTAGAGGTTGTAGACAAGACT
CAGGTGTCACGGACCCGCATGGCTGTGGTGGACACAGTAATTGGGGGTCGCCTGCGGCTCCTCT
ATGAGGATGGTGACAGTGATGATGACTTCTGGTGCCATATGTGGAGTCCCCTGATCCATCCAGT
GGGTTGGTCACGGCGTGTTGGCCACGGCATCAAGATGTCAGAGAGACGATGTGACATGTCTCAT
CACCCTACCTTCCGGAAAATCTACTGTGATGCTGTTCCTTACCTCTTCAAGAAGGTCCGAGCTG
TCTACACAGAAGGTGGTTGGTTTGAGGAAGGAATGAAACTAGAGGCCATTGACCCTCTGAATCT
GGGCAATATCTGTGTAGCAACCATCTGCAAGGTGCTCCTGGATGGTTACCTGATGATCTGTGTG
GATGGGGGGCCGTCCACGGATGGCTCAGATTGGTTCTGCTACCACGCCTCCTCCCACGCCATCT
TCCCAGCCACCTTCTGCCAAAAGAATGACATCGAGCTCACACCCCCAAAAGGGTATGAGACACA
GCCTTTTGACTGGGAGAGCTACTTAGAAAAGACCAAGTCAAAAGCAGCTCCAGCGAGACTCTTT
AACATGGACTGCCCCAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCTGTGGACTTGATGG
AGCCACGGCTCATCTGTGTGGCCACCGTGAAGCGAGTGGTGCATCGTCTCCTGAGCATCCACTT
CGATGGCTGGGACAACGAGTATGATCAGTGGGTGGACTGCGAGTCCCCCGACATCTACCCTGTT
GGCTGGTGTGAACTCACCGGCTACCAGCTCCAGCCGCCCGTGTCCGCAGAACCAAACACACCTC
AGAAAGGCAAGGATGCCACGAAGAAGAAGAAGAAGCAGTTTGGGAAGAAAAGGAAAAGAATCCC
GTCAGCCAAGACTCGGCCCCTCAGACAGAGCTCCAAGAAACCCTTACTGGAGGACAACCTTGAG
GCTTTGGGGGTCTCGGAACCAGTTCCTGATGACATCATCGCTGTGTGTGTGAAAGAGGAGCACC
AGGACCTGCCCTCGCCTGACAGGTCACCCAGTCCACTGCTGCCTCTCCCCACCGAGAGTATCAA
GCAAGAAAGGGACAGCTGAGACTTCCCTGGCATCAGCCTGGAGGCTGCCTGAAGCCAAGCCTGG
TCACGAGCAAAGAGGGGGCCGGCTTTACTGTTCTGCAGCAAGTGTCCAGGGCCTCCCTCCGCCC
TCTGCACAGGCCTGCTGACAGGTCAGCTTGAGTTCTAAGCTGGCACACTCATTGCACCTCAGCA
CACTGGAAAACGAGACTGATCCCCATGTGTCTACCCAGGCGAGTGGTGGAAGTAAGGCTATGGA
GCAGCTGTAGGTGGGCAGCCCATGCTGACGCTGGGTGTGGACATAGCCACCTCTGCCCAAAATA
AATTGAGCATCCTATACCTCCTGGGGGCACCCTGCCTGATGTCCCAGGAGCCCCACTGTGGCAG
GTGATTGACCAAGGTAGTGGGTTTGAACTTTGACCTCAGGGATGGCAAGAACACTGACGTCTTT
CTTAGAGGGAATGGTTGGGAAGACATATAGGGACCTGTGGCCCTAAGGGAAACATGGGCCAGGC
TGCCTGCTGTTGGGCACAGGACCAGACAGTAGTTGACCCATGCAGTCTGGGGTGCTGACTGAGA
CCATCCTCTAGAGCTGAGCTTGGGTTGGACCTAAGGTTTCCATTCCCCTGCCTGGTCAGCAGGG
CCACTGCTCAGCATACCGTCGCTACAGTGTTGGCTTTTGATTTCCCACTTAGACACTTTAGTTG
TTTTTTTTTGTTTTGTTTTGTTTTGTTTTCTGGAGCTGGGGACCGAACCCAGGGCCTTGTGCTT
GCTAGGCAAGCACTCTACCACTGAGCTAAATCCCCAGCCCCTAGTTGTTTATTTTTGAGACAGG
GTCTATGTAGTACTTGCTGTTCTGGAGCTTGAGATGTAGCCCATGCAGATAAACTGATAGGGAT
CCCCCTGTCTCCGCCTCCTCGTGCTGGGATAAAGCTGTGCGTCCAGCCCCCAGCTAGACACTTT
GGAACTGGTGGTGTAGCCCTCAGTATCATCTTGAACACCAGTTGGGGCTCCTGCAGTGCCCTTT
GTGCTTCACTGGGTTTTGGACGAAGCAGTGAGGCCCCTGCTTCCTGTCATGTAGTGACTGTAGT
GTGCTGCGTGACTATCTCGGTCAAGTCCCGTCAAGAAGATGAAAGTCCACAGCAAAAGGCAGGT
TCGATTCCCAGTGCCTGCTCACAGCTGCCTGTATCTTGATCTGCAGGGGACCCTGTGCCTCTGG
TTTCTGTGGATACAAATGTGTATGCCCTTAAAAATCATTAAAAAAAAAAAAAAAAACTTTGAAA
AAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008765711 ⟹ XP_008763933

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	122,896,860 - 122,918,025 (+)	NCBI

Sequence:

show sequence

GCAGCTCGGGCGGGGTAGCCAATGAGCACACTCTCGGAGAGCGGTGAGGGCAATATGGCTTCCT
GCACCTGGTGACGGTTGAGGAAATTGAATTTGGTATCATGGAGAAGCCGCGGGGCACTGAGGAG
ACGCCATCTTCAGAGCCAATGGAAGAGGAGGAAGATGATGACTTGGAACTCTTCGGAGGCTACG
ATAGCTTCCGGAGTTACAACAGCAGTGCGGGCAGTGAGAGCAGCTCCTACTTGGAGGAGTCAAG
TGAAGCAGAAAATGAGGATCGGGAAGCAGGGGAGCTGCCCACCTCACCTCTGCATCTGTTCAGC
TCTGCGAATAACCGCGCCTTGGATGGCAGTGGTTCTGAGCCAGCTGTCTGTGAGATGTGTGGTA
TTGTGGGCACCAGAGAAGCTTTCTTTTCAAAGACCAAGAGGTTCTGCAGTGTCTCATGTTCCAG
GAGCTACTCTTCCAACTCCAAGAAAGCCAGTATCTTGGCTAGACTTCAGGGAAAGCCCCCCACC
AAGAAAGCCAAAGTCCTGCACAAAGCAGCCTGGTCCGCCAAAATTGGAGCCTTCCTCCACGCCC
AGGGAACAGGACAGCTAGCAGATGGGACACCCACAGGACAAGACGCTCTAGTCTTGGGGTTCGA
CTGGGGGAAGTTCCTGAAGGATCACAGTTACAAGGCTGCTCCTGTCGGCTGCTTTAAACACGTA
CCCCTCTATGACCAGTGGGAGGACGTCATGAAGGGGATGAAGGTAGAAGTCCTCAACAGCGACG
CCGTGCTCCCCAGCCGGGTGTACTGGATCGCCACTGTCATCCAGGCAGCTGGGTACCGGGTACT
GCTCCGATATGAAGGCTTTGAGAATGACGCCAGTCATGACTTCTGGTGCAACCTGGGGACTGTG
GACGTCCACCCCATTGGGTGGTGTGCCATCAACAGCAAGATCCTGGTGCCTCCACGGACCATCC
ATGCCAAGTTTACTGACTGGAAGAGCTACCTCATGAAGCGGTTGGTGGGATCCAGGACACTTCC
TGCAGATTTCCATATCAAGATGGTAGAAAGCATGAAGTACCCTTTTCGGCAGGGCATGCGCTTA
GAGGTTGTAGACAAGACTCAGGTGTCACGGACCCGCATGGCTGTGGTGGACACAGTAATTGGGG
GTCGCCTGCGGCTCCTCTATGAGGATGGTGACAGTGATGATGACTTCTGGTGCCATATGTGGAG
TCCCCTGATCCATCCAGTGGGTTGGTCACGGCGTGTTGGCCACGGCATCAAGATGTCAGAGAGA
CGATGTGACATGTCTCATCACCCTACCTTCCGGAAAATCTACTGTGATGCTGTTCCTTACCTCT
TCAAGAAGGTCCGAGCTGTCTACACAGAAGGTGGTTGGTTTGAGGAAGGAATGAAACTAGAGGC
CATTGACCCTCTGAATCTGGGCAATATCTGTGTAGCAACCATCTGCAAGGTGCTCCTGGATGGT
TACCTGATGATCTGTGTGGATGGGGGGCCGTCCACGGATGGCTCAGATTGGTTCTGCTACCACG
CCTCCTCCCACGCCATCTTCCCAGCCACCTTCTGCCAAAAGAATGACATCGAGCTCACACCCCC
AAAAGGGTATGAGACACAGCCTTTTGACTGGGAGAGCTACTTAGAAAAGACCAAGTCAAAAGCA
GCTCCAGCGAGACTCTTTAACATGGACTGCCCCAACCATGGCTTCAAGGTGGGCATGAAGCTGG
AGGCTGTGGACTTGATGGAGCCACGGCTCATCTGTGTGGCCACCGTGAAGCGAGTGGTGCATCG
TCTCCTGAGCATCCACTTCGATGGCTGGGACAACGAGTATGATCAGTGGGTGGACTGCGAGTCC
CCCGACATCTACCCTGTTGGCTGGTGTGAACTCACCGGCTACCAGCTCCAGCCGCCCGTGTCCG
CAGAACCAAACACACCTCAGAAAGGCAAGGATGCCACGAAGAAGAAGAAGAAGCAGTTTGGGAA
GAAAAGGAAAAGAATCCCGTCAGCCAAGACTCGGCCCCTCAGACAGAGCTCCAAGAAACCCTTA
CTGGAGGACAACCTTGAGGCTTTGGGGGTCTCGGAACCAGTTCCTGATGACAGTCACCCAGTCC
ACTGCTGCCTCTCCCCACCGAGAGTATCAAGCAAGAAAGGGACAGCTGAGACTTCCCTGGCATC
AGCCTGGAGGCTGCCTGAAGCCAAGCCTGGTCACGAGCAAAGAGGGGGCCGGCTTTACTGTTCT
GCAGCAAGTGTCCAGGGCCTCCCTCCGCCCTCTGCACAGGCCTGCTGACAGGTCAGCTTGAGTT
CTAAGCTGGCACACTCATTGCACCTCAGCACACTGGAAAACGAGACTGATCCCCATGTGTCTAC
CCAGGCGAGTGGTGGAAGTAAGGCTATGGAGCAGCTGTAGGTGGGCAGCCCATGCTGACGCTGG
GTGTGGACATAGCCACCTCTGCCCAAAATAAATTGAGCATCCTATACCTCCTGGGGGCACCCTG
CCTGATGTCCCAGGAGCCCCACTGTGGCAGGTGATTGACCAAGGTAGTGGGTTTGAACTTTGAC
CTCAGGGATGGCAAGAACACTGACGTCTTTCTTAGAGGGAATGGTTGGGAAGACATATAGGGAC
CTGTGGCCCTAAGGGAAACATGGGCCAGGCTGCCTGCTGTTGGGCACAGGACCAGACAGTAGTT
GACCCATGCAGTCTGGGGTGCTGACTGAGACCATCCTCTAGAGCTGAGCTTGGGTTGGACCTAA
GGTTTCCATTCCCCTGCCTGGTCAGCAGGGCCACTGCTCAGCATACCGTCGCTACAGTGTTGGC
TTTTGATTTCCCACTTAGACACTTTAGTTGTTTTTTTTTGTTTTGTTTTGTTTTGTTTTCTGGA
GCTGGGGACCGAACCCAGGGCCTTGTGCTTGCTAGGCAAGCACTCTACCACTGAGCTAAATCCC
CAGCCCCTAGTTGTTTATTTTTGAGACAGGGTCTATGTAGTACTTGCTGTTCTGGAGCTTGAGA
TGTAGCCCATGCAGATAAACTGATAGGGATCCCCCTGTCTCCGCCTCCTCGTGCTGGGATAAAG
CTGTGCGTCCAGCCCCCAGCTAGACACTTTGGAACTGGTGGTGTAGCCCTCAGTATCATCTTGA
ACACCAGTTGGGGCTCCTGCAGTGCCCTTTGTGCTTCACTGGGTTTTGGACGAAGCAGTGAGGC
CCCTGCTTCCTGTCATGTAGTGACTGTAGTGTGCTGCGTGACTATCTCGGTCAAGTCCCGTCAA
GAAGATGAAAGTCCACAGCAAAAGGCAGGTTCGATTCCCAGTGCCTGCTCACAGCTGCCTGTAT
CTTGATCTGCAGGGGACCCTGTGCCTCTGGTTTCTGTGGATACAAATGTGTATGCCCTTAAAAA
TCATTAAAAAAAAAAAAAAACTTTGAAGAAAA

hide sequence

RefSeq Acc Id:

XM_017594794 ⟹ XP_017450283

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	122,896,877 - 122,918,025 (+)	NCBI

Sequence:

show sequence

GCCAATGAGCACACTCTCGGAGAGCGGTGAGGGCAATATGGCTTCCTGCACCTGGTGACGGTTG
AGGAAATTGAATTTGGTATCATGGAGAAGCCGCGGGGCACTGAGGAGACGCCATCTTCAGAGCC
AATGGAAGAGGAGGAAGATGATGACTTGGAACTCTTCGGAGGCTACGATAGCTTCCGGAGTTAC
AACAGCAGTGCGGGCAGTGAGAGCAGCTCCTACTTGGAGGAGTCAAGTGAAGCAGAAAATGAGG
ATCGGGAAGCAGGGGAGCTGCCCACCTCACCTCTGCATCTGTTCAGCTCTGCGAATAACCGCGC
CTTGGATGGCAGTGGTTCTGAGCCAGGTGCTTTCACAGTGGCCTCAAAGAGAGAGAGGAGGCAG
GAGGCTGTGGAAGAATCGGGGATGTGGGCGGAGCCATCCAGACTGTCCTTAAGGGTCATTTTCT
CTCTGCAGTCTGGTTTCCAAGTCTTGTTCTCCAAGTCTTGTGTTTGCTCAGCGCTTGTTAAATT
CCATTCTATGTGGACTAGGCTAGGCAGTCCCCGAGTCTGGATCTGAAGACAGTGAGACTCAGTG
GTGTGAGTACTTTTGAACAGAGGGACAAGAGGTAGCTTGTGGGCTGCAGGCTGGCAAGTGGGGG
TAGGGGATGTACAGGATAAAGTGGTCTTCAGGTCAGAAGGCAGGTGCAGAGGTGGGCAGAAGGG
AGTGGCCATGAACCATCTGGAAGCCAGTTGACTTCAAAAAGATGGTGCTTGGATGGCTGCTAGG
CCCTGTGTGGGGGTGTGCAGAGTGGGCAGTGTGTCCTTGAAAAGAGGCAGGCTCCAATCTTCAA
ACAGCCCCTCTGTGCCTTCCACTGGCACTGGTGGGCCATGCGTCAGCTTTCCTTCCGCTCATCC
TGGCTTTTCCTATTTTACTTGTTCATCTTTCTTCCTCTGTCTTCTTCCCGCCCTTCTCTTAGGA
GCTGAGAGTCAGGACTAGCAGGGGTCATTAGGGAGAGCAGCTGAGCCCAGGGGCTGGTGTAACC
CTGGCTGCAGGTTAGCCTCATCTGGGGAGCTGGAAAAGCCCTTCAGATGGTCATGGCAATCTCC
AACCACAACACTGTTTACAGAAGGCTCCTCAGCTGTCTGTGAGATGTGTGGTATTGTGGGCACC
AGAGAAGCTTTCTTTTCAAAGACCAAGAGGTTCTGCAGTGTCTCATGTTCCAGGAGCTACTCTT
CCAACTCCAAGAAAGCCAGTATCTTGGCTAGACTTCAGGGAAAGCCCCCCACCAAGAAAGCCAA
AGTCCTGCACAAAGCAGCCTGGTCCGCCAAAATTGGAGCCTTCCTCCACGCCCAGGGAACAGGA
CAGCTAGCAGATGGGACACCCACAGGACAAGACGCTCTAGTCTTGGGGTTCGACTGGGGGAAGT
TCCTGAAGGATCACAGTTACAAGGCTGCTCCTGTCGGCTGCTTTAAACACGTACCCCTCTATGA
CCAGTGGGAGGACGTCATGAAGGGGATGAAGGTAGAAGTCCTCAACAGCGACGCCGTGCTCCCC
AGCCGGGTGTACTGGATCGCCACTGTCATCCAGGCAGCTGGGTACCGGGTACTGCTCCGATATG
AAGGCTTTGAGAATGACGCCAGTCATGACTTCTGGTGCAACCTGGGGACTGTGGACGTCCACCC
CATTGGGTGGTGTGCCATCAACAGCAAGATCCTGGTGCCTCCACGGACCATCCATGCCAAGTTT
ACTGACTGGAAGAGCTACCTCATGAAGCGGTTGGTGGGATCCAGGACACTTCCTGCAGATTTCC
ATATCAAGATGGTAGAAAGCATGAAGTACCCTTTTCGGCAGGGCATGCGCTTAGAGGTTGTAGA
CAAGACTCAGGTGTCACGGACCCGCATGGCTGTGGTGGACACAGTAATTGGGGGTCGCCTGCGG
CTCCTCTATGAGGATGGTGACAGTGATGATGACTTCTGGTGCCATATGTGGAGTCCCCTGATCC
ATCCAGTGGGTTGGTCACGGCGTGTTGGCCACGGCATCAAGATGTCAGAGAGACGATGTGACAT
GTCTCATCACCCTACCTTCCGGAAAATCTACTGTGATGCTGTTCCTTACCTCTTCAAGAAGGTC
CGAGCTGTCTACACAGAAGGTGGTTGGTTTGAGGAAGGAATGAAACTAGAGGCCATTGACCCTC
TGAATCTGGGCAATATCTGTGTAGCAACCATCTGCAAGGTGCTCCTGGATGGTTACCTGATGAT
CTGTGTGGATGGGGGGCCGTCCACGGATGGCTCAGATTGGTTCTGCTACCACGCCTCCTCCCAC
GCCATCTTCCCAGCCACCTTCTGCCAAAAGAATGACATCGAGCTCACACCCCCAAAAGGGTATG
AGACACAGCCTTTTGACTGGGAGAGCTACTTAGAAAAGACCAAGTCAAAAGCAGCTCCAGCGAG
ACTCTTTAACATGGACTGCCCCAACCATGGCTTCAAGGTGGGCATGAAGCTGGAGGCTGTGGAC
TTGATGGAGCCACGGCTCATCTGTGTGGCCACCGTGAAGCGAGTGGTGCATCGTCTCCTGAGCA
TCCACTTCGATGGCTGGGACAACGAGTATGATCAGTGGGTGGACTGCGAGTCCCCCGACATCTA
CCCTGTTGGCTGGTGTGAACTCACCGGCTACCAGCTCCAGCCGCCCGTGTCCGCAGAACCAAAC
ACACCTCAGAAAGGCAAGGATGCCACGAAGAAGAAGAAGAAGCAGTTTGGGAAGAAAAGGAAAA
GAATCCCGTCAGCCAAGACTCGGCCCCTCAGACAGAGCTCCAAGAAACCCTTACTGGAGGACAA
CCTTGAGGCTTTGGGGGTCTCGGAACCAGTTCCTGATGACATCATCGCTGTGTGTGTGAAAGAG
GAGCACCAGGACCTGCCCTCGCCTGACAGGTCACCCAGTCCACTGCTGCCTCTCCCCACCGAGA
GTATCAAGCAAGAAAGGGACAGCTGAGACTTCCCTGGCATCAGCCTGGAGGCTGCCTGAAGCCA
AGCCTGGTCACGAGCAAAGAGGGGGCCGGCTTTACTGTTCTGCAGCAAGTGTCCAGGGCCTCCC
TCCGCCCTCTGCACAGGCCTGCTGACAGGTCAGCTTGAGTTCTAAGCTGGCACACTCATTGCAC
CTCAGCACACTGGAAAACGAGACTGATCCCCATGTGTCTACCCAGGCGAGTGGTGGAAGTAAGG
CTATGGAGCAGCTGTAGGTGGGCAGCCCATGCTGACGCTGGGTGTGGACATAGCCACCTCTGCC
CAAAATAAATTGAGCATCCTATACCTCCTGGGGGCACCCTGCCTGATGTCCCAGGAGCCCCACT
GTGGCAGGTGATTGACCAAGGTAGTGGGTTTGAACTTTGACCTCAGGGATGGCAAGAACACTGA
CGTCTTTCTTAGAGGGAATGGTTGGGAAGACATATAGGGACCTGTGGCCCTAAGGGAAACATGG
GCCAGGCTGCCTGCTGTTGGGCACAGGACCAGACAGTAGTTGACCCATGCAGTCTGGGGTGCTG
ACTGAGACCATCCTCTAGAGCTGAGCTTGGGTTGGACCTAAGGTTTCCATTCCCCTGCCTGGTC
AGCAGGGCCACTGCTCAGCATACCGTCGCTACAGTGTTGGCTTTTGATTTCCCACTTAGACACT
TTAGTTGTTTTTTTTTGTTTTGTTTTGTTTTGTTTTCTGGAGCTGGGGACCGAACCCAGGGCCT
TGTGCTTGCTAGGCAAGCACTCTACCACTGAGCTAAATCCCCAGCCCCTAGTTGTTTATTTTTG
AGACAGGGTCTATGTAGTACTTGCTGTTCTGGAGCTTGAGATGTAGCCCATGCAGATAAACTGA
TAGGGATCCCCCTGTCTCCGCCTCCTCGTGCTGGGATAAAGCTGTGCGTCCAGCCCCCAGCTAG
ACACTTTGGAACTGGTGGTGTAGCCCTCAGTATCATCTTGAACACCAGTTGGGGCTCCTGCAGT
GCCCTTTGTGCTTCACTGGGTTTTGGACGAAGCAGTGAGGCCCCTGCTTCCTGTCATGTAGTGA
CTGTAGTGTGCTGCGTGACTATCTCGGTCAAGTCCCGTCAAGAAGATGAAAGTCCACAGCAAAA
GGCAGGTTCGATTCCCAGTGCCTGCTCACAGCTGCCTGTATCTTGATCTGCAGGGGACCCTGTG
CCTCTGGTTTCTGTGGATACAAATGTGTATGCCCTTAAAAATCATTAAAAAAAAAAAAAAACTT
TGAAGAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001028867	(Get FASTA)	NCBI Sequence Viewer
	XP_008763933	(Get FASTA)	NCBI Sequence Viewer
	XP_017450283	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI01866	(Get FASTA)	NCBI Sequence Viewer
	EDM15714	(Get FASTA)	NCBI Sequence Viewer
	EDM15715	(Get FASTA)	NCBI Sequence Viewer
	EDM15716	(Get FASTA)	NCBI Sequence Viewer
	Q3MIF2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001028867 ⟸ NM_001033695

- UniProtKB:

Q3MIF2 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MEKPRGTEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREAGEL
PTSPLHLFSSANNRALDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASIL
ARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKA
APVGCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASH
DFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMK
YPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRV
GHGIKMSERRCDMSHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVA
TICKVLLDGYLMICVDGGPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFDWES
YLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNE
YDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDATKKKKKQFGKKRKRIPSAKTRP
LRQSSKKPLLEDNLEALGVSEPVPDDIIAVCVKEEHQDLPSPDRSPSPLLPLPTESIKQERDS

hide sequence

RefSeq Acc Id:

XP_008763933 ⟸ XM_008765711

- Peptide Label:

isoform X2

- Sequence:

show sequence

MEKPRGTEETPSSEPMEEEEDDDLELFGGYDSFRSYNSSAGSESSSYLEESSEAENEDREAGEL
PTSPLHLFSSANNRALDGSGSEPAVCEMCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASIL
ARLQGKPPTKKAKVLHKAAWSAKIGAFLHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKA
APVGCFKHVPLYDQWEDVMKGMKVEVLNSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASH
DFWCNLGTVDVHPIGWCAINSKILVPPRTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMK
YPFRQGMRLEVVDKTQVSRTRMAVVDTVIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRV
GHGIKMSERRCDMSHHPTFRKIYCDAVPYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVA
TICKVLLDGYLMICVDGGPSTDGSDWFCYHASSHAIFPATFCQKNDIELTPPKGYETQPFDWES
YLEKTKSKAAPARLFNMDCPNHGFKVGMKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNE
YDQWVDCESPDIYPVGWCELTGYQLQPPVSAEPNTPQKGKDATKKKKKQFGKKRKRIPSAKTRP
LRQSSKKPLLEDNLEALGVSEPVPDDSHPVHCCLSPPRVSSKKGTAETSLASAWRLPEAKPGHE
QRGGRLYCSAASVQGLPPPSAQAC

hide sequence

RefSeq Acc Id:

XP_017450283 ⟸ XM_017594794

- Peptide Label:

isoform X1

- Sequence:

show sequence

MCGIVGTREAFFSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLHKAAWSAKIGAF
LHAQGTGQLADGTPTGQDALVLGFDWGKFLKDHSYKAAPVGCFKHVPLYDQWEDVMKGMKVEVL
NSDAVLPSRVYWIATVIQAAGYRVLLRYEGFENDASHDFWCNLGTVDVHPIGWCAINSKILVPP
RTIHAKFTDWKSYLMKRLVGSRTLPADFHIKMVESMKYPFRQGMRLEVVDKTQVSRTRMAVVDT
VIGGRLRLLYEDGDSDDDFWCHMWSPLIHPVGWSRRVGHGIKMSERRCDMSHHPTFRKIYCDAV
PYLFKKVRAVYTEGGWFEEGMKLEAIDPLNLGNICVATICKVLLDGYLMICVDGGPSTDGSDWF
CYHASSHAIFPATFCQKNDIELTPPKGYETQPFDWESYLEKTKSKAAPARLFNMDCPNHGFKVG
MKLEAVDLMEPRLICVATVKRVVHRLLSIHFDGWDNEYDQWVDCESPDIYPVGWCELTGYQLQP
PVSAEPNTPQKGKDATKKKKKQFGKKRKRIPSAKTRPLRQSSKKPLLEDNLEALGVSEPVPDDI
IAVCVKEEHQDLPSPDRSPSPLLPLPTESIKQERDS

hide sequence

RefSeq Acc Id:

ENSRNOP00000031908 ⟸ ENSRNOT00000034998

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695512

Promoter ID:

EPDNEW_R6037

Type:

multiple initiation site

Name:

L3mbtl2_1

Description:

L3MBTL2 polycomb repressive complex 1 subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	122,896,887 - 122,896,947	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308569	AgrOrtholog
Ensembl Genes	ENSRNOG00000024743	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000031908	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000034998	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.60.160	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7365719	IMAGE-MGC_LOAD
	IMAGE:7938856	IMAGE-MGC_LOAD
InterPro	L3MBTL2	UniProtKB/Swiss-Prot
	Mbt	UniProtKB/Swiss-Prot
	Znf_FCS	UniProtKB/Swiss-Prot
	Znf_FCS_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:300320	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:109590	IMAGE-MGC_LOAD
	MGC:124862	IMAGE-MGC_LOAD
NCBI Gene	300320	ENTREZGENE
PANTHER	PTHR12247:SF64	UniProtKB/Swiss-Prot
Pfam	MBT	UniProtKB/Swiss-Prot
PhenoGen	L3mbtl2	PhenoGen
PROSITE	MBT	UniProtKB/Swiss-Prot
	ZF_FCS	UniProtKB/Swiss-Prot
SMART	MBT	UniProtKB/Swiss-Prot
UniGene	Rn.137566	ENTREZGENE
UniProt	LMBL2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-10	L3mbtl2	L3MBTL histone methyl-lysine binding protein 2	L3mbtl2	L3MBTL2 polycomb repressive complex 1 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-04-27	L3mbtl2	L3MBTL2 polycomb repressive complex 1 subunit	L3mbtl2	l(3)mbt-like 2 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	L3mbtl2	l(3)mbt-like 2 (Drosophila)	L3mbtl2_predicted	l(3)mbt-like 2 (Drosophila) (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	L3mbtl2_predicted	l(3)mbt-like 2 (Drosophila) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD