Gene: L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2) Rattus norvegicus
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Symbol: L3mbtl2
Name: L3MBTL histone methyl-lysine binding protein 2
Description: ENCODES a protein that exhibits histone binding (ortholog); methylated histone binding (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN ectoderm development (ortholog); negative regulation of gene expression (ortholog); negative regulation of histone acetylation (ortholog); ASSOCIATED WITH medulloblastoma (ortholog); nephronophthisis-like nephropathy 1 (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; flutamide
AGR Description: Predicted to have methylated histone binding activity and promoter-specific chromatin binding activity; predicted to be involved in several processes, including ectoderm development, negative regulation of macromolecule metabolic process, and positive regulation of histone methylation; predicted to localize to the nucleus; orthologous to human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2).
Merged Description: Predicted to have methylated histone binding activity and promoter-specific chromatin binding activity; predicted to be involved in several processes, including ectoderm development, negative regulation of macromolecule metabolic process, and positive regulation of histone methylation; predicted to localize to the nucleus; orthologous to human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2); INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; flutamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: l(3)mbt-like 2 (Drosophila); l(3)mbt-like 2 protein; l(3)mbt-like protein 2; L3MBTL histone methyl-lysine binding protein 2; L3mbtl2; L3MBTL2 polycomb repressive complex 1 subunit; lethal(3)malignant brain tumor-like 2 protein; lethal(3)malignant brain tumor-like protein 2; LOC300320; MGC124862
Orthologs:
Homo sapiens (human) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)  HGNC  Alliance
Mus musculus (house mouse) : L3mbtl2 (L3MBTL2 polycomb repressive complex 1 subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)
Canis lupus familiaris (dog) : L3MBTL2 (L3MBTL2, polycomb repressive complex 1 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : L3mbtl2 (L3MBTL histone methyl-lysine binding protein 2)
Sus scrofa (pig) : L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07122,896,860 - 122,918,025 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07122,871,375 - 122,892,521 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,016,773 - 120,037,852 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17120,050,975 - 120,071,944 (+)NCBI
Celera7109,505,411 - 109,526,484 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on L3mbtl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 1308569
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.