Smug1 (single-strand-selective monofunctional uracil-DNA glycosylase 1) - Rat Genome Database

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Gene: Smug1 (single-strand-selective monofunctional uracil-DNA glycosylase 1) Rattus norvegicus
Analyze
Symbol: Smug1
Name: single-strand-selective monofunctional uracil-DNA glycosylase 1
RGD ID: 631403
Description: Enables oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity and single-strand selective uracil DNA N-glycosylase activity. Involved in base-excision repair. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Orthologous to human SMUG1 (single-strand-selective monofunctional uracil-DNA glycosylase 1); PARTICIPATES IN base excision repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: single-strand selective monofunctional uracil DNA glycosylase; single-strand selective monofunctional uracil-DNA glycosylase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27134,288,565 - 134,302,179 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,287,675 - 134,297,226 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7136,045,289 - 136,047,414 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07138,274,666 - 138,276,791 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07138,260,724 - 138,262,849 (-)NCBIRnor_WKY
Rnor_6.07144,774,155 - 144,788,333 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,774,160 - 144,778,656 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,560,270 - 142,569,924 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,064,428 - 142,066,553 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17142,144,616 - 142,151,752 (-)NCBI
Celera7130,715,767 - 130,717,892 (-)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)
fibrillar center  (IEA,ISO)
nucleolus  (ISO,ISS)
nucleoplasm  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions. Masaoka A, etal., Biochemistry 2003 May 6;42(17):5003-12.
3. Mammalian 5-formyluracil-DNA glycosylase. 1. Identification and characterization of a novel activity that releases 5-formyluracil from DNA. Matsubara M, etal., Biochemistry. 2003 May 6;42(17):4993-5002.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Testicular protein Spag5 has similarity to mitotic spindle protein Deepest and binds outer dense fiber protein Odf1. Shao X, etal., Mol Reprod Dev 2001 Aug;59(4):410-6.
Additional References at PubMed
PMID:11526119   PMID:12161446  


Genomics

Comparative Map Data
Smug1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27134,288,565 - 134,302,179 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7134,287,675 - 134,297,226 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7136,045,289 - 136,047,414 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.07138,274,666 - 138,276,791 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.07138,260,724 - 138,262,849 (-)NCBIRnor_WKY
Rnor_6.07144,774,155 - 144,788,333 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,774,160 - 144,778,656 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07142,560,270 - 142,569,924 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,064,428 - 142,066,553 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17142,144,616 - 142,151,752 (-)NCBI
Celera7130,715,767 - 130,717,892 (-)NCBICelera
Cytogenetic Map7q36NCBI
SMUG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381254,158,235 - 54,188,985 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1254,121,277 - 54,189,008 (-)EnsemblGRCh38hg38GRCh38
GRCh371254,574,150 - 54,582,769 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,861,519 - 52,869,024 (-)NCBINCBI36Build 36hg18NCBI36
Celera1254,226,170 - 54,233,675 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1251,611,811 - 51,620,446 (-)NCBIHuRef
CHM1_11254,540,762 - 54,549,526 (-)NCBICHM1_1
T2T-CHM13v2.01254,145,927 - 54,154,492 (-)NCBIT2T-CHM13v2.0
Smug1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,061,717 - 103,077,360 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15103,061,717 - 103,075,519 (-)EnsemblGRCm39 Ensembl
GRCm3815103,153,290 - 103,168,939 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,153,290 - 103,167,092 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715102,983,721 - 102,993,715 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,981,324 - 102,991,318 (-)NCBIMGSCv36mm8
Celera15105,314,542 - 105,324,536 (-)NCBICelera
Cytogenetic Map15F3NCBI
Smug1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554581,431,721 - 1,447,292 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554581,432,988 - 1,449,019 (-)NCBIChiLan1.0ChiLan1.0
SMUG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11235,288,412 - 35,296,670 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1235,288,412 - 35,296,670 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01234,564,624 - 34,572,063 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SMUG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,086,675 - 1,093,175 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,089,808 - 1,111,129 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2745,157,542 - 45,164,017 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,088,178 - 1,094,647 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl271,088,357 - 1,235,362 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,107,011 - 1,113,490 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,088,345 - 1,094,825 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02745,561,546 - 45,568,018 (-)NCBIUU_Cfam_GSD_1.0
Smug1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,762,394 - 61,796,876 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493651211,395,513 - 11,416,426 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMUG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,398,252 - 19,412,648 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1519,375,244 - 19,412,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2520,035,790 - 20,050,156 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMUG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,292,780 - 50,307,828 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1150,289,154 - 50,300,492 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037195,741,787 - 195,751,095 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smug1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249042,223,600 - 2,231,642 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249042,185,959 - 2,232,541 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7119513385135012528Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:65
Count of miRNA genes:62
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000055290
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 12 6 9 6 56 21 33 10
Low 3 31 45 35 10 35 8 11 18 14 8 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000055290   ⟹   ENSRNOP00000052164
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl7144,776,531 - 144,778,656 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082149   ⟹   ENSRNOP00000069685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7134,287,675 - 134,297,226 (-)Ensembl
Rnor_6.0 Ensembl7144,774,160 - 144,778,339 (-)Ensembl
RefSeq Acc Id: NM_177934   ⟹   NP_808795
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,290,048 - 134,292,173 (-)NCBI
Rnor_6.07144,776,531 - 144,778,656 (-)NCBI
Rnor_5.07142,560,270 - 142,569,924 (-)NCBI
RGSC_v3.47142,064,428 - 142,066,553 (-)RGD
Celera7130,715,767 - 130,717,892 (-)RGD
Sequence:
RefSeq Acc Id: XM_008765749   ⟹   XP_008763971
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,288,565 - 134,299,453 (-)NCBI
Rnor_6.07144,776,467 - 144,788,330 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594900   ⟹   XP_017450389
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,288,565 - 134,300,990 (-)NCBI
Rnor_6.07144,774,155 - 144,788,329 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079347   ⟹   XP_038935275
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,288,565 - 134,302,179 (-)NCBI
RefSeq Acc Id: XM_039079348   ⟹   XP_038935276
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.27134,288,565 - 134,299,462 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_808795   ⟸   NM_177934
- UniProtKB: Q811Q1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008763971   ⟸   XM_008765749
- Peptide Label: isoform X1
- UniProtKB: Q811Q1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017450389   ⟸   XM_017594900
- Peptide Label: isoform X1
- UniProtKB: Q811Q1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000052164   ⟸   ENSRNOT00000055290
RefSeq Acc Id: ENSRNOP00000069685   ⟸   ENSRNOT00000082149
RefSeq Acc Id: XP_038935275   ⟸   XM_039079347
- Peptide Label: isoform X1
- UniProtKB: Q811Q1 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038935276   ⟸   XM_039079348
- Peptide Label: isoform X1
- UniProtKB: Q811Q1 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q811Q1-F1-model_v2 AlphaFold Q811Q1 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631403 AgrOrtholog
BioCyc Gene G2FUF-31886 BioCyc
Ensembl Genes ENSRNOG00000036842 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000069685 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000082149 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.470.10 UniProtKB/Swiss-Prot
InterPro SMUG1 UniProtKB/Swiss-Prot
  Uracil-DNA_glycosylase-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:315344 UniProtKB/Swiss-Prot
NCBI Gene 315344 ENTREZGENE
PANTHER PTHR13235 UniProtKB/Swiss-Prot
PharmGKB SMUG1 RGD
PhenoGen Smug1 PhenoGen
Superfamily-SCOP SSF52141 UniProtKB/Swiss-Prot
UniProt Q811Q1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Smug1  single-strand-selective monofunctional uracil-DNA glycosylase 1  Smug1  single-strand selective monofunctional uracil DNA glycosylase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Smug1  single-strand selective monofunctional uracil DNA glycosylase      Symbol and Name status set to approved 625702 APPROVED