C7h8orf33 (similar to human chromosome 8 open reading frame 33) - Rat Genome Database

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Gene: C7h8orf33 (similar to human chromosome 8 open reading frame 33) Rattus norvegicus
Analyze
Symbol: C7h8orf33
Name: similar to human chromosome 8 open reading frame 33
RGD ID: 1597990
Description: Orthologous to human C8orf33 (chromosome 8 open reading frame 33); INTERACTS WITH 2-palmitoylglycerol (ortholog); aflatoxin B1 (ortholog); all-trans-retinoic acid (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC681282; LOC681282; UPF0488 protein C8orf33 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,562,735 - 110,564,985 (+)NCBIGRCr8
mRatBN7.27108,682,122 - 108,684,372 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,682,176 - 108,684,358 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,425,092 - 110,427,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,648,675 - 112,650,929 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,610,104 - 112,612,357 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07118,023,363 - 118,025,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,023,628 - 118,025,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07118,007,537 - 118,009,774 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,010,035 - 115,012,027 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7105,030,557 - 105,032,815 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C7h8orf33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87110,562,735 - 110,564,985 (+)NCBIGRCr8
mRatBN7.27108,682,122 - 108,684,372 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,682,176 - 108,684,358 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7110,425,092 - 110,427,345 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,648,675 - 112,650,929 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07112,610,104 - 112,612,357 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07118,023,363 - 118,025,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7118,023,628 - 118,025,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07118,007,537 - 118,009,774 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47115,010,035 - 115,012,027 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7105,030,557 - 105,032,815 (+)NCBICelera
Cytogenetic Map7q34NCBI
C8orf33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388145,052,467 - 145,056,030 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8145,052,465 - 145,066,685 (+)EnsemblGRCh38hg38GRCh38
GRCh378146,277,853 - 146,281,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368146,248,630 - 146,252,220 (+)NCBINCBI36Build 36hg18NCBI36
Celera8142,454,766 - 142,458,407 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8141,393,625 - 141,397,217 (+)NCBIHuRef
CHM1_18146,316,100 - 146,319,692 (+)NCBICHM1_1
T2T-CHM13v2.08146,229,380 - 146,234,031 (+)NCBIT2T-CHM13v2.0
1110038F14Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,832,453 - 76,835,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,832,706 - 76,835,179 (+)EnsemblGRCm39 Ensembl
GRCm381576,948,251 - 76,950,979 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,948,506 - 76,950,979 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,778,974 - 76,781,162 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,775,799 - 76,777,987 (+)NCBIMGSCv36mm8
Celera1578,443,569 - 78,445,757 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1536.3NCBI
CUNH8orf33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554543,515,979 - 3,520,341 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554543,515,898 - 3,518,046 (+)NCBIChiLan1.0ChiLan1.0
C7H8orf33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27162,550,471 - 162,567,101 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18138,103,842 - 138,120,583 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08141,824,715 - 141,841,705 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
C13H8orf33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11338,216,273 - 38,224,449 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1338,183,447 - 38,185,390 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,696,652 - 38,698,595 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,696,025 - 38,698,818 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11338,387,962 - 38,389,905 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01338,497,328 - 38,499,271 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,972,250 - 38,974,193 (+)NCBIUU_Cfam_GSD_1.0
CUNH8orf33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,497 - 49,773 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493738246,352 - 49,707 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493738247,374 - 49,701 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C4H8orf33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1446,008 - 61,713 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2472,911 - 91,742 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH8orf33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18139,253,682 - 139,255,767 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8139,253,640 - 139,255,489 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666039583,634 - 585,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH8orf33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473511,972,104 - 11,978,203 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473511,976,128 - 11,978,365 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C7h8orf33
14 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:129
Count of miRNA genes:108
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000041750
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)780221299109401111Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)780221299112308525Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)794811326116294265Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat

Markers in Region
RH143865  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,682,197 - 108,682,324 (+)MAPPERmRatBN7.2
Rnor_6.07118,023,447 - 118,023,573NCBIRnor6.0
Rnor_5.07118,007,600 - 118,007,726UniSTSRnor5.0
RGSC_v3.47115,009,854 - 115,009,980UniSTSRGSC3.4
Celera7105,030,641 - 105,030,767UniSTS
RH 3.4 Map7793.5UniSTS
Cytogenetic Map7q34UniSTS
AA891551  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27108,684,010 - 108,684,158 (+)MAPPERmRatBN7.2
Rnor_6.07118,025,260 - 118,025,407NCBIRnor6.0
Rnor_5.07118,009,413 - 118,009,560UniSTSRnor5.0
RGSC_v3.47115,011,666 - 115,011,813UniSTSRGSC3.4
Celera7105,032,454 - 105,032,601UniSTS
RH 3.4 Map7790.0UniSTS
Cytogenetic Map7q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 40 45 29 19 29 8 11 71 35 37 11 8
Low 3 12 12 12 3 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000041750   ⟹   ENSRNOP00000050313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7108,682,176 - 108,684,358 (+)Ensembl
Rnor_6.0 Ensembl7118,023,628 - 118,025,287 (+)Ensembl
RefSeq Acc Id: NM_001398982   ⟹   NP_001385911
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,562,735 - 110,564,985 (+)NCBI
mRatBN7.27108,682,122 - 108,684,372 (+)NCBI
RefSeq Acc Id: NM_001398983   ⟹   NP_001385912
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87110,562,735 - 110,564,985 (+)NCBI
mRatBN7.27108,682,122 - 108,684,372 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001385911 (Get FASTA)   NCBI Sequence Viewer  
  NP_001385912 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM15925 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000050313
  ENSRNOP00000050313.4
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000050313   ⟸   ENSRNOT00000041750
RefSeq Acc Id: NP_001385911   ⟸   NM_001398982
- Peptide Label: isoform 1
- UniProtKB: D3ZDG0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001385912   ⟸   NM_001398983
- Peptide Label: isoform 2
- UniProtKB: A6HSE8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDG0-F1-model_v2 AlphaFold D3ZDG0 1-222 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695447
Promoter ID:EPDNEW_R5967
Type:multiple initiation site
Name:LOC681282_1
Description:hypothetical protein LOC681282
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07118,023,617 - 118,023,677EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1597990 AgrOrtholog
BioCyc Gene G2FUF-32893 BioCyc
Ensembl Genes ENSRNOG00000034107 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041750 ENTREZGENE
  ENSRNOT00000041750.5 UniProtKB/TrEMBL
InterPro DUF4615 UniProtKB/TrEMBL
KEGG Report rno:681282 UniProtKB/TrEMBL
NCBI Gene 681282 ENTREZGENE
PANTHER PTHR13602 UniProtKB/TrEMBL
  UPF0488 PROTEIN C8ORF33 UniProtKB/TrEMBL
Pfam DUF4615 UniProtKB/TrEMBL
PhenoGen C7h8orf33 PhenoGen
RatGTEx ENSRNOG00000034107 RatGTEx
UniProt A6HSE8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDG0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-27 C7h8orf33  similar to human chromosome 8 open reading frame 33  LOC681282  hypothetical protein LOC681282  Name and Symbol changed 629549 APPROVED
2006-11-20 LOC681282  hypothetical protein LOC681282      Symbol and Name status set to provisional 70820 PROVISIONAL