(-)-epigallocatechin 3-gallate multiple interactions ISO GSDMD (Homo sapiens) 6480464 epigallocatechin gallate inhibits the reaction [bisphenol A results in increased expression of GSDMD mRNA] and epigallocatechin gallate inhibits the reaction [bisphenol A results in increased expression of GSDMD protein] CTD PMID:35439536 (1->4)-beta-D-glucan multiple interactions ISO Gsdmd (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GSDMD mRNA CTD PMID:36331819 (S)-ropivacaine multiple interactions ISO GSDMD (Homo sapiens) 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein] more ... CTD PMID:36858639 (S)-ropivacaine increases cleavage ISO GSDMD (Homo sapiens) 6480464 Ropivacaine results in increased cleavage of GSDMD protein CTD PMID:36858639 1,1-dichloroethene increases expression ISO Gsdmd (Mus musculus) 6480464 vinylidene chloride results in increased expression of GSDMD mRNA CTD PMID:26682919 1,2-dimethylhydrazine multiple interactions ISO Gsdmd (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GSDMD mRNA CTD PMID:22206623 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GSDMD mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GSDMD mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gsdmd (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GSDMD mRNA CTD PMID:19933214 and PMID:23994337 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gsdmd (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GSDMD mRNA CTD PMID:21570461 2,5-hexanedione multiple interactions EXP 6480464 Glyburide inhibits the reaction [2 and 5-hexanedione results in increased cleavage of GSDMD protein] CTD PMID:32522579 and PMID:32860822 2,5-hexanedione increases cleavage EXP 6480464 2 and 5-hexanedione results in increased cleavage of GSDMD protein CTD PMID:32522579 and PMID:32860822 2-palmitoylglycerol increases expression ISO GSDMD (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of GSDMD mRNA CTD PMID:37199045 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Gsdmd (Mus musculus) 6480464 3 more ... CTD PMID:23994337 3-chloropropane-1,2-diol increases cleavage EXP 6480464 alpha-Chlorohydrin results in increased cleavage of GSDMD protein CTD PMID:33187795 3-methylcholanthrene increases expression ISO Gsdmd (Mus musculus) 6480464 Methylcholanthrene results in increased expression of GSDMD mRNA CTD PMID:20713471 4-phenylbutyric acid multiple interactions ISO Gsdmd (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of GSDMD mRNA] CTD PMID:30796460 4-phenylbutyric acid multiple interactions ISO GSDMD (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 and PMID:36646296 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of GSDMD mRNA and Propylthiouracil results in increased expression of GSDMD protein CTD PMID:37047793 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO Gsdmd (Mus musculus) 6480464 [lipopolysaccharide more ... CTD PMID:36577999 aflatoxin B1 decreases expression ISO GSDMD (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of GSDMD mRNA CTD PMID:27153756 aflatoxin B1 increases expression ISO Gsdmd (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of GSDMD mRNA and Aflatoxin B1 results in increased expression of GSDMD protein CTD PMID:35063475 aflatoxin B1 multiple interactions ISO Gsdmd (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of GSDMD mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of GSDMD protein] CTD PMID:35063475 Aflatoxin B2 alpha decreases methylation ISO GSDMD (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of GSDMD intron CTD PMID:30157460 aldehydo-D-glucose increases expression ISO Gsdmd (Mus musculus) 6480464 Glucose results in increased expression of GSDMD mRNA CTD PMID:34212273 aldehydo-D-glucose increases cleavage ISO GSDMD (Homo sapiens) 6480464 Glucose results in increased cleavage of GSDMD protein CTD PMID:35607288 aldehydo-D-glucose multiple interactions ISO GSDMD (Homo sapiens) 6480464 loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA] more ... CTD PMID:35607288 and PMID:37473909 aldehydo-D-glucose increases expression ISO GSDMD (Homo sapiens) 6480464 Glucose results in increased expression of GSDMD mRNA and Glucose results in increased expression of GSDMD protein CTD PMID:37473909 aldehydo-D-glucose multiple interactions ISO Gsdmd (Mus musculus) 6480464 Glucose results in increased expression of and results in increased cleavage of GSDMD protein more ... CTD PMID:34212273 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of GSDMD mRNA CTD PMID:20488242 antirheumatic drug decreases expression ISO GSDMD (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of GSDMD mRNA CTD PMID:24449571 apocynin multiple interactions ISO GSDMD (Homo sapiens) 6480464 acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of GSDMD protein] CTD PMID:30378427 aristolochic acid A increases cleavage EXP 6480464 aristolochic acid I results in increased cleavage of GSDMD protein CTD PMID:36863539 ATP multiple interactions ISO GSDMD (Homo sapiens) 6480464 [Adenosine Triphosphate co-treated with lipopolysaccharide more ... CTD PMID:33851234 more ... ATP multiple interactions ISO Gsdmd (Mus musculus) 6480464 [lipopolysaccharide more ... CTD PMID:34212273 and PMID:36577999 ATP multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein more ... CTD PMID:35962723 benzo[a]pyrene increases expression ISO Gsdmd (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of GSDMD mRNA CTD PMID:20713471 more ... benzo[a]pyrene decreases methylation ISO GSDMD (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of GSDMD exon and Benzo(a)pyrene results in decreased methylation of GSDMD promoter CTD PMID:27901495 benzo[a]pyrene affects methylation ISO GSDMD (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of GSDMD 5' UTR and Benzo(a)pyrene affects the methylation of GSDMD intron CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene diol epoxide I multiple interactions ISO GSDMD (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 benzo[b]fluoranthene increases expression ISO Gsdmd (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of GSDMD mRNA CTD PMID:26377693 benzo[e]pyrene decreases methylation ISO GSDMD (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of GSDMD intron CTD PMID:30157460 beta-cyclodextrin multiple interactions ISO Gsdmd (Mus musculus) 6480464 [myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant co-treated with Pertussis Toxin co-treated with betadex] results in increased expression of GSDMD protein and lonidamine inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant co-treated with Pertussis Toxin co-treated with betadex] results in increased expression of GSDMD protein] CTD PMID:36577999 beta-naphthoflavone increases expression ISO Gsdmd (Mus musculus) 6480464 beta-Naphthoflavone results in increased expression of GSDMD mRNA CTD PMID:23994337 bisphenol A decreases expression ISO GSDMD (Homo sapiens) 6480464 bisphenol A results in decreased expression of GSDMD mRNA CTD PMID:19371625 bisphenol A increases expression ISO GSDMD (Homo sapiens) 6480464 bisphenol A results in increased expression of GSDMD mRNA and bisphenol A results in increased expression of GSDMD protein CTD PMID:35439536 bisphenol A multiple interactions ISO GSDMD (Homo sapiens) 6480464 benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [bisphenol A results in increased expression of GSDMD mRNA] more ... CTD PMID:35439536 bisphenol A decreases methylation ISO GSDMD (Homo sapiens) 6480464 bisphenol A results in decreased methylation of GSDMD gene CTD PMID:31601247 bisphenol A increases expression ISO Gsdmd (Mus musculus) 6480464 bisphenol A results in increased expression of GSDMD mRNA CTD PMID:33221593 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of GSDMD gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GSDMD mRNA CTD PMID:25181051 cadmium dichloride affects expression EXP 6480464 Cadmium Chloride affects the expression of GSDMD mRNA CTD PMID:22110744 cadmium dichloride multiple interactions ISO Gsdmd (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of GSDMD mRNA] CTD PMID:30796460 cadmium dichloride increases expression ISO GSDMD (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of GSDMD mRNA CTD PMID:30796460 cadmium dichloride multiple interactions ISO GSDMD (Homo sapiens) 6480464 SIRT1 protein inhibits the reaction [Cadmium Chloride results in increased expression of GSDMD mRNA] more ... CTD PMID:30796460 cannabidiol decreases expression ISO GSDMD (Homo sapiens) 6480464 Cannabidiol results in decreased expression of GSDMD protein CTD PMID:34269108 cannabidiol multiple interactions ISO GSDMD (Homo sapiens) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]] and Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein] CTD PMID:34269108 carbon nanotube increases expression ISO Gsdmd (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of GSDMD mRNA CTD PMID:25554681 carbon nanotube decreases expression ISO Gsdmd (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 chloroquine multiple interactions ISO GSDMD (Homo sapiens) 6480464 Chloroquine promotes the reaction [[lipopolysaccharide and Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of and results in increased cleavage of GSDMD protein] CTD PMID:34920032 chlorquinaldol multiple interactions ISO Gsdmd (Mus musculus) 6480464 Chlorquinaldol inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of and results in increased secretion of GSDMD protein] CTD PMID:36002070 cisplatin multiple interactions ISO GSDMD (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of GSDMD mRNA CTD PMID:27392435 copper atom multiple interactions ISO GSDMD (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of GSDMD mRNA CTD PMID:20971185 copper(0) multiple interactions ISO GSDMD (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of GSDMD mRNA CTD PMID:20971185 copper(II) sulfate increases expression ISO Gsdmd (Mus musculus) 6480464 Copper Sulfate results in increased expression of GSDMD mRNA and Copper Sulfate results in increased expression of GSDMD protein CTD PMID:37353053 copper(II) sulfate multiple interactions ISO Gsdmd (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of GSDMD mRNA] more ... CTD PMID:37353053 curcumin multiple interactions ISO Gsdmd (Mus musculus) 6480464 [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide more ... CTD PMID:34998855 and PMID:35063475 cyclosporin A decreases expression ISO Gsdmd (Mus musculus) 6480464 Cyclosporine results in decreased expression of GSDMD mRNA CTD PMID:19770486 D-glucose increases expression ISO GSDMD (Homo sapiens) 6480464 Glucose results in increased expression of GSDMD mRNA and Glucose results in increased expression of GSDMD protein CTD PMID:37473909 D-glucose increases cleavage ISO GSDMD (Homo sapiens) 6480464 Glucose results in increased cleavage of GSDMD protein CTD PMID:35607288 D-glucose multiple interactions ISO GSDMD (Homo sapiens) 6480464 loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA] more ... CTD PMID:35607288 and PMID:37473909 D-glucose multiple interactions ISO Gsdmd (Mus musculus) 6480464 Glucose results in increased expression of and results in increased cleavage of GSDMD protein more ... CTD PMID:34212273 D-glucose increases expression ISO Gsdmd (Mus musculus) 6480464 Glucose results in increased expression of GSDMD mRNA CTD PMID:34212273 deoxynivalenol increases expression ISO Gsdmd (Mus musculus) 6480464 deoxynivalenol results in increased expression of GSDMD mRNA and deoxynivalenol results in increased expression of GSDMD protein CTD PMID:36309173 deoxynivalenol multiple interactions ISO Gsdmd (Mus musculus) 6480464 deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD mRNA] more ... CTD PMID:35925383 and PMID:36309173 dexamethasone multiple interactions ISO Gsdmd (Mus musculus) 6480464 [Dexamethasone co-treated with Curcumin] inhibits the reaction [[Ovalbumin co-treated with lipopolysaccharide and Escherichia coli O111 B4] results in increased expression of GSDMD protein] CTD PMID:34998855 dexmedetomidine multiple interactions ISO GSDMD (Homo sapiens) 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein] more ... CTD PMID:36858639 dextran sulfate increases cleavage ISO Gsdmd (Mus musculus) 6480464 Dextran Sulfate results in increased cleavage of GSDMD protein CTD PMID:37001609 dextran sulfate multiple interactions ISO Gsdmd (Mus musculus) 6480464 hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased cleavage of GSDMD protein] and Mesalamine inhibits the reaction [Dextran Sulfate results in increased cleavage of GSDMD protein] CTD PMID:37001609 diquat decreases expression ISO Gsdmd (Mus musculus) 6480464 Diquat results in decreased expression of GSDMD protein CTD PMID:36851058 disulfiram multiple interactions ISO GSDMD (Homo sapiens) 6480464 Disulfiram binds to and results in decreased activity of GSDMD protein and Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein] CTD PMID:32367036 and PMID:33851234 disulfiram decreases cleavage ISO GSDMD (Homo sapiens) 6480464 Disulfiram results in decreased cleavage of GSDMD protein CTD PMID:33851234 folic acid multiple interactions ISO Gsdmd (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GSDMD mRNA CTD PMID:22206623 fulvestrant multiple interactions ISO GSDMD (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased expression of GSDMD mRNA] and Fulvestrant inhibits the reaction [bisphenol A results in increased expression of GSDMD protein] CTD PMID:35439536 fumonisin B1 multiple interactions ISO Gsdmd (Mus musculus) 6480464 deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of GSDMD mRNA] more ... CTD PMID:36309173 fumonisin B1 increases expression ISO Gsdmd (Mus musculus) 6480464 fumonisin B1 results in increased expression of GSDMD mRNA and fumonisin B1 results in increased expression of GSDMD protein CTD PMID:36309173 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of GSDMD mRNA CTD PMID:24136188 glucose multiple interactions ISO Gsdmd (Mus musculus) 6480464 Glucose results in increased expression of and results in increased cleavage of GSDMD protein more ... CTD PMID:34212273 glucose increases cleavage ISO GSDMD (Homo sapiens) 6480464 Glucose results in increased cleavage of GSDMD protein CTD PMID:35607288 glucose multiple interactions ISO GSDMD (Homo sapiens) 6480464 loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA] more ... CTD PMID:35607288 and PMID:37473909 glucose increases expression ISO GSDMD (Homo sapiens) 6480464 Glucose results in increased expression of GSDMD mRNA and Glucose results in increased expression of GSDMD protein CTD PMID:37473909 glucose increases expression ISO Gsdmd (Mus musculus) 6480464 Glucose results in increased expression of GSDMD mRNA CTD PMID:34212273 glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [2 and 5-hexanedione results in increased cleavage of GSDMD protein] CTD PMID:32522579 and PMID:32860822 glycerol multiple interactions EXP 6480464 Pentoxifylline inhibits the reaction [Glycerol results in increased cleavage of GSDMD protein] and Thiamine inhibits the reaction [Glycerol results in increased cleavage of GSDMD protein] CTD PMID:36690085 glycerol increases cleavage EXP 6480464 Glycerol results in increased cleavage of GSDMD protein CTD PMID:36690085 glycidol increases cleavage EXP 6480464 glycidol results in increased cleavage of GSDMD protein CTD PMID:33187795 graphene oxide increases expression ISO GSDMD (Homo sapiens) 6480464 graphene oxide results in increased expression of GSDMD mRNA CTD PMID:33973267 GW 4064 multiple interactions ISO Gsdmd (Mus musculus) 6480464 GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased cleavage of GSDMD protein] CTD PMID:36328986 hyaluronic acid increases cleavage EXP 6480464 Hyaluronic Acid results in increased cleavage of GSDMD protein CTD PMID:33383130 hyaluronic acid increases expression EXP 6480464 Hyaluronic Acid results in increased expression of GSDMD mRNA CTD PMID:33383130 hydroquinone increases expression ISO GSDMD (Homo sapiens) 6480464 hydroquinone results in increased expression of GSDMD protein CTD PMID:36646296 hydroquinone multiple interactions ISO GSDMD (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased expression of GSDMD protein] more ... CTD PMID:36646296 hydroxysafflor yellow A multiple interactions ISO GSDMD (Homo sapiens) 6480464 HK1 protein affects the reaction [hydroxysafflor yellow A inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide more ... CTD PMID:37001609 hydroxysafflor yellow A multiple interactions ISO Gsdmd (Mus musculus) 6480464 hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased cleavage of GSDMD protein] CTD PMID:37001609 imiquimod multiple interactions ISO Gsdmd (Mus musculus) 6480464 [lipopolysaccharide more ... CTD PMID:36577999 isoflurane increases cleavage ISO Gsdmd (Mus musculus) 6480464 Isoflurane results in increased cleavage of GSDMD protein CTD PMID:35187972 isoflurane multiple interactions ISO Gsdmd (Mus musculus) 6480464 SETD7 protein affects the reaction [Isoflurane results in increased cleavage of GSDMD protein] CTD PMID:35187972 ivermectin decreases expression ISO GSDMD (Homo sapiens) 6480464 Ivermectin results in decreased expression of GSDMD protein CTD PMID:32959892 lipopolysaccharide multiple interactions ISO GSDMD (Homo sapiens) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]] more ... CTD PMID:33851234 more ... lipopolysaccharide increases expression ISO Gsdmd (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of GSDMD protein CTD PMID:37379125 lipopolysaccharide multiple interactions ISO Gsdmd (Mus musculus) 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased cleavage of GSDMD protein more ... CTD PMID:34212273 more ... lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein more ... CTD PMID:35962723 lipopolysaccharide increases cleavage ISO GSDMD (Homo sapiens) 6480464 Lipopolysaccharides results in increased cleavage of GSDMD protein CTD PMID:34791735 loganin multiple interactions ISO GSDMD (Homo sapiens) 6480464 loganin inhibits the reaction [Glucose results in increased expression of GSDMD mRNA] and loganin inhibits the reaction [Glucose results in increased expression of GSDMD protein] CTD PMID:37473909 loganin multiple interactions ISO Gsdmd (Mus musculus) 6480464 loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA] and loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein] CTD PMID:37473909 lonidamine multiple interactions ISO Gsdmd (Mus musculus) 6480464 lonidamine inhibits the reaction [[lipopolysaccharide more ... CTD PMID:36577999 luteolin multiple interactions ISO GSDMD (Homo sapiens) 6480464 Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of GSDMD protein] CTD PMID:34217685 luteolin multiple interactions ISO Gsdmd (Mus musculus) 6480464 Luteolin inhibits the reaction [Lipopolysaccharides results in increased expression of GSDMD protein] CTD PMID:37379125 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased cleavage of GSDMD protein]] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium bisulfide inhibits the reaction [uranyl acetate results in increased expression of GSDMD mRNA]] CTD PMID:36094782 and PMID:36898572 mesalamine multiple interactions ISO Gsdmd (Mus musculus) 6480464 Mesalamine inhibits the reaction [Dextran Sulfate results in increased cleavage of GSDMD protein] CTD PMID:37001609 methapyrilene decreases methylation ISO GSDMD (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of GSDMD intron CTD PMID:30157460 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Gsdmd (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of GSDMD mRNA] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased expression of GSDMD protein] CTD PMID:37353053 N-acetyl-L-cysteine multiple interactions ISO GSDMD (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein] more ... CTD PMID:30378427 more ... N-acetyl-L-cysteine increases expression ISO GSDMD (Homo sapiens) 6480464 Acetylcysteine results in increased expression of GSDMD protein CTD PMID:36646296 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of GSDMD protein] CTD PMID:36347317 N-acetyl-L-cysteine multiple interactions ISO Gsdmd (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD mRNA] and Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD protein] CTD PMID:36354081 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO GSDMD (Homo sapiens) 6480464 [lipopolysaccharide more ... CTD PMID:34920032 nickel atom increases expression ISO GSDMD (Homo sapiens) 6480464 Nickel results in increased expression of GSDMD mRNA CTD PMID:25583101 nigericin multiple interactions EXP 6480464 Nigericin inhibits the reaction [peiminine inhibits the reaction [Particulate Matter results in increased cleavage of GSDMD protein]] CTD PMID:36898572 nigericin multiple interactions ISO Gsdmd (Mus musculus) 6480464 [lipopolysaccharide more ... CTD PMID:36002070 and PMID:36577999 obeticholic acid multiple interactions ISO Gsdmd (Mus musculus) 6480464 obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased cleavage of GSDMD protein] CTD PMID:36328986 ochratoxin A increases expression ISO Gsdmd (Mus musculus) 6480464 ochratoxin A results in increased expression of GSDMD mRNA and ochratoxin A results in increased expression of GSDMD protein CTD PMID:33543323 ozone multiple interactions EXP 6480464 Ozone results in increased expression of and results in increased cleavage of GSDMD protein CTD PMID:33383130 paclitaxel multiple interactions ISO GSDMD (Homo sapiens) 6480464 benzyloxycarbonyltyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [Paclitaxel results in increased expression of and results in increased cleavage of GSDMD protein] and Paclitaxel results in increased expression of and results in increased cleavage of GSDMD protein CTD PMID:31993881 paclitaxel affects response to substance ISO GSDMD (Homo sapiens) 6480464 GSDMD protein affects the susceptibility to Paclitaxel CTD PMID:31993881 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of GSDMD mRNA CTD PMID:33387578 patulin multiple interactions ISO GSDMD (Homo sapiens) 6480464 ATG5 protein affects the reaction [Patulin results in increased expression of and results in increased cleavage of GSDMD protein] more ... CTD PMID:33217525 Pentoxifylline multiple interactions EXP 6480464 Pentoxifylline inhibits the reaction [Glycerol results in increased cleavage of GSDMD protein] CTD PMID:36690085 perfluorohexanesulfonic acid increases expression ISO Gsdmd (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of GSDMD mRNA CTD PMID:37995155 perfluorooctane-1-sulfonic acid increases cleavage ISO Gsdmd (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased cleavage of GSDMD protein CTD PMID:34006824 perfluorooctane-1-sulfonic acid multiple interactions ISO Gsdmd (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of GSDMD mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of GSDMD mRNA CTD PMID:36331819 pirinixic acid multiple interactions ISO Gsdmd (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GSDMD mRNA CTD PMID:19710929 pirinixic acid decreases expression ISO Gsdmd (Mus musculus) 6480464 pirinixic acid results in decreased expression of GSDMD mRNA CTD PMID:23811191 quartz multiple interactions ISO Gsdmd (Mus musculus) 6480464 GSDMD promotes the reaction [Quartz results in increased secretion of IL1A protein] CTD PMID:36840754 quercetin multiple interactions ISO GSDMD (Homo sapiens) 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein] and Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]] CTD PMID:34791735 resveratrol multiple interactions ISO Gsdmd (Mus musculus) 6480464 Resveratrol inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD mRNA] and Resveratrol inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD protein] CTD PMID:34614429 scutellarin multiple interactions EXP 6480464 scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein] CTD PMID:37081038 sevoflurane increases expression EXP 6480464 Sevoflurane results in increased expression of GSDMD protein modified form CTD PMID:36155068 sevoflurane multiple interactions EXP 6480464 PHLDA1 protein promotes the reaction [Sevoflurane results in increased expression of GSDMD protein modified form] CTD PMID:36155068 sodium arsenite multiple interactions EXP 6480464 sodium arsenite results in increased expression of and results in decreased ubiquitination of GSDMD protein and sodium arsenite results in increased expression of and results in increased cleavage of GSDMD protein CTD PMID:34920032 sodium arsenite increases expression ISO GSDMD (Homo sapiens) 6480464 sodium arsenite results in increased expression of GSDMD mRNA CTD PMID:34032870 sodium arsenite multiple interactions ISO GSDMD (Homo sapiens) 6480464 [lipopolysaccharide more ... CTD PMID:34920032 sorafenib increases expression ISO GSDMD (Homo sapiens) 6480464 Sorafenib results in increased expression of GSDMD protein CTD PMID:33271325 streptozocin increases expression ISO Gsdmd (Mus musculus) 6480464 Streptozocin results in increased expression of GSDMD mRNA CTD PMID:34212273 streptozocin multiple interactions EXP 6480464 scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein] CTD PMID:37081038 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of GSDMD protein CTD PMID:37081038 streptozocin affects response to substance ISO Gsdmd (Mus musculus) 6480464 GSDMD protein affects the susceptibility to Streptozocin CTD PMID:34212273 streptozocin multiple interactions ISO Gsdmd (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA more ... CTD PMID:34212273 and PMID:37473909 temozolomide increases expression ISO GSDMD (Homo sapiens) 6480464 Temozolomide results in increased expression of GSDMD mRNA CTD PMID:31758290 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of GSDMD mRNA CTD PMID:31150632 thapsigargin increases expression ISO GSDMD (Homo sapiens) 6480464 Thapsigargin results in increased expression of GSDMD mRNA CTD PMID:30796460 thiamine(1+) chloride multiple interactions EXP 6480464 Thiamine inhibits the reaction [Glycerol results in increased cleavage of GSDMD protein] CTD PMID:36690085 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of GSDMD mRNA CTD PMID:23411599 Triptolide increases expression EXP 6480464 triptolide results in increased expression of GSDMD protein CTD PMID:32519852 Triptolide multiple interactions ISO Gsdmd (Mus musculus) 6480464 [triptolide co-treated with Lipopolysaccharides] results in increased cleavage of GSDMD protein more ... CTD PMID:36328986 valproic acid decreases expression ISO GSDMD (Homo sapiens) 6480464 Valproic Acid results in decreased expression of GSDMD mRNA CTD PMID:29154799 and PMID:29501571 valproic acid increases methylation ISO GSDMD (Homo sapiens) 6480464 Valproic Acid results in increased methylation of GSDMD gene CTD PMID:29154799 and PMID:29501571 valproic acid affects expression ISO GSDMD (Homo sapiens) 6480464 Valproic Acid affects the expression of GSDMD mRNA CTD PMID:25979313 valproic acid affects expression ISO Gsdmd (Mus musculus) 6480464 Valproic Acid affects the expression of GSDMD mRNA CTD PMID:17963808 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of GSDMD mRNA CTD PMID:23034163 zearalenone decreases expression ISO GSDMD (Homo sapiens) 6480464 Zearalenone results in decreased expression of GSDMD mRNA CTD PMID:19371625 zinc protoporphyrin multiple interactions ISO GSDMD (Homo sapiens) 6480464 zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein]] CTD PMID:36858639