Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Copz1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPZ1 mRNA | CTD | PMID:22206623 | Copz1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COPZ1 mRNA | CTD | PMID:17942748 | Copz1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of COPZ1 mRNA | CTD | PMID:17942748 | Copz1 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Copz1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Copz1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COPZ1 mRNA | CTD | PMID:17942748 | Copz1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Copz1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of COPZ1 mRNA | CTD | PMID:21570461 | Copz1 | Rat | 2,4,6-tribromophenol | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Copz1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of COPZ1 mRNA | CTD | PMID:21346803 | Copz1 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of COPZ1 mRNA | CTD | PMID:21346803 | Copz1 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of COPZ1 protein | CTD | PMID:31675489 | Copz1 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of COPZ1 mRNA | CTD | PMID:20188158 | Copz1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of COPZ1 mRNA | CTD | PMID:28628672 | Copz1 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of COPZ1 mRNA | CTD | PMID:36041667 | Copz1 | Rat | acrolein | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of COPZ1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of COPZ1 mRNA | CTD | PMID:32699268 | Copz1 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of COPZ1 mRNA | CTD | PMID:28959563 | Copz1 | Rat | alpha-pinene | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of COPZ1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of COPZ1 mRNA | CTD | PMID:32699268 | Copz1 | Rat | arsenite(3-) | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to COPZ1 mRNA] | CTD | PMID:32406909 | Copz1 | Rat | atrazine | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Atrazine results in increased expression of COPZ1 mRNA | CTD | PMID:22378314 | Copz1 | Rat | benzo[a]pyrene | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of COPZ1 mRNA | CTD | PMID:26238291 | Copz1 | Rat | bisphenol A | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of COPZ1 mRNA and bisphenol A results in increased expression of COPZ1 protein | CTD | PMID:25047013 more ... | Copz1 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of COPZ1 mRNA | CTD | PMID:36041667 | Copz1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of COPZ1 gene | CTD | PMID:28505145 | Copz1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of COPZ1 mRNA | CTD | PMID:25181051 | Copz1 | Rat | bisphenol AF | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of COPZ1 protein | CTD | PMID:34186270 | Copz1 | Rat | bisphenol F | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of COPZ1 mRNA | CTD | PMID:28628672 | Copz1 | Rat | bisphenol F | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of COPZ1 protein | CTD | PMID:34186270 | Copz1 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of COPZ1 mRNA | CTD | PMID:36041667 | Copz1 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of COPZ1 mRNA | CTD | PMID:19167457 | Copz1 | Rat | carbon nanotube | decreases expression | ISO | Copz1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of COPZ1 mRNA | CTD | PMID:25620056 | Copz1 | Rat | chlorpyrifos | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of COPZ1 mRNA | CTD | PMID:37019170 | Copz1 | Rat | copper(II) sulfate | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of COPZ1 mRNA | CTD | PMID:19549813 | Copz1 | Rat | crocidolite asbestos | decreases expression | ISO | Copz1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of COPZ1 mRNA | CTD | PMID:29279043 | Copz1 | Rat | crocidolite asbestos | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in increased expression of COPZ1 mRNA | CTD | PMID:29523930 | Copz1 | Rat | cyclosporin A | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of COPZ1 mRNA | CTD | PMID:20106945 | Copz1 | Rat | dexamethasone | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of COPZ1 mRNA | CTD | PMID:28628672 | Copz1 | Rat | dextran sulfate | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of COPZ1 protein] | CTD | PMID:35362542 | Copz1 | Rat | dextran sulfate | decreases expression | ISO | Copz1 (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of COPZ1 protein | CTD | PMID:35362542 | Copz1 | Rat | Dibutyl phosphate | affects expression | ISO | COPZ1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of COPZ1 mRNA | CTD | PMID:37042841 | Copz1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of COPZ1 mRNA | CTD | PMID:21266533 | Copz1 | Rat | disodium selenite | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of COPZ1 mRNA | CTD | PMID:18175754 | Copz1 | Rat | ethanol | affects splicing | ISO | Copz1 (Mus musculus) | 6480464 | Ethanol affects the splicing of COPZ1 mRNA | CTD | PMID:30319688 | Copz1 | Rat | Evodiamine | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of COPZ1 protein] | CTD | PMID:35362542 | Copz1 | Rat | fenthion | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | Fenthion results in increased expression of COPZ1 mRNA | CTD | PMID:34813904 | Copz1 | Rat | folic acid | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of COPZ1 mRNA | CTD | PMID:22206623 | Copz1 | Rat | genistein | decreases expression | ISO | Copz1 (Mus musculus) | 6480464 | Genistein results in decreased expression of COPZ1 mRNA | CTD | PMID:32186404 | Copz1 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of COPZ1 mRNA | CTD | PMID:24136188 | Copz1 | Rat | hydrazine | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | hydrazine results in increased expression of COPZ1 mRNA | CTD | PMID:15282401 | Copz1 | Rat | indometacin | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of COPZ1 mRNA | CTD | PMID:28628672 | Copz1 | Rat | ivermectin | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of COPZ1 protein | CTD | PMID:32959892 | Copz1 | Rat | ketoconazole | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Ketoconazole results in decreased expression of COPZ1 mRNA | CTD | PMID:36621641 | Copz1 | Rat | methidathion | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | methidathion results in increased expression of COPZ1 mRNA | CTD | PMID:34813904 | Copz1 | Rat | ozone | multiple interactions | ISO | COPZ1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of COPZ1 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | Copz1 | Rat | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of COPZ1 mRNA | CTD | PMID:27638505 | Copz1 | Rat | paracetamol | multiple interactions | ISO | Copz1 (Mus musculus) | 6480464 | PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of COPZ1 mRNA] | CTD | PMID:29246445 | Copz1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of COPZ1 mRNA | CTD | PMID:33387578 | Copz1 | Rat | paracetamol | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of COPZ1 mRNA | CTD | PMID:29246445 | Copz1 | Rat | perfluorooctanoic acid | increases expression | ISO | Copz1 (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of COPZ1 protein | CTD | PMID:37422089 | Copz1 | Rat | rotenone | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Rotenone results in increased expression of COPZ1 mRNA | CTD | PMID:33512557 | Copz1 | Rat | sodium arsenite | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of COPZ1 protein | CTD | PMID:30528433 | Copz1 | Rat | T-2 toxin | increases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | T-2 Toxin results in increased expression of COPZ1 mRNA | CTD | PMID:31863870 | Copz1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of COPZ1 mRNA | CTD | PMID:34492290 | Copz1 | Rat | urethane | decreases expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of COPZ1 mRNA | CTD | PMID:28818685 | Copz1 | Rat | valproic acid | affects expression | ISO | COPZ1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of COPZ1 mRNA | CTD | PMID:25979313 | Copz1 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of COPZ1 mRNA | CTD | PMID:19015723 | Copz1 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of COPZ1 mRNA | CTD | PMID:23034163 | |