Copz1 (coatomer protein complex, subunit zeta 1) - Rat Genome Database

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Gene: Copz1 (coatomer protein complex, subunit zeta 1) Mus musculus
Analyze
Symbol: Copz1
Name: coatomer protein complex, subunit zeta 1
RGD ID: 1314608
MGI Page MGI
Description: Acts upstream of or within toxin transport. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and membrane. Predicted to be part of COPI vesicle coat. Orthologous to human COPZ1 (COPI coat complex subunit zeta 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5930435A22Rik; AA407760; coatomer subunit zeta-1; D4Ertd360; D4Ertd360e; MGC118060; nonclathrin coat protein zeta1-COP; zeta-1 COP; zeta-1-coat protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,181,261 - 103,208,295 (+)NCBIGRCm39mm39
GRCm39 Ensembl15103,181,141 - 103,208,295 (+)Ensembl
GRCm3815103,272,888 - 103,299,865 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,272,714 - 103,299,868 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715103,103,349 - 103,130,296 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615103,100,952 - 103,127,899 (+)NCBImm8
Celera15105,435,330 - 105,462,717 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1558.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:17360540   PMID:17967808   PMID:18799693   PMID:21267068   PMID:21873635   PMID:23716698   PMID:24457600   PMID:30550785   PMID:32325033  


Genomics

Comparative Map Data
Copz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915103,181,261 - 103,208,295 (+)NCBIGRCm39mm39
GRCm39 Ensembl15103,181,141 - 103,208,295 (+)Ensembl
GRCm3815103,272,888 - 103,299,865 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15103,272,714 - 103,299,868 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715103,103,349 - 103,130,296 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615103,100,952 - 103,127,899 (+)NCBImm8
Celera15105,435,330 - 105,462,717 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1558.74NCBI
COPZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1254,301,202 - 54,351,846 (+)EnsemblGRCh38hg38GRCh38
GRCh381254,325,109 - 54,351,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371254,718,915 - 54,745,630 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361253,005,178 - 53,031,900 (+)NCBINCBI36hg18NCBI36
Build 341253,005,177 - 53,031,900NCBI
Celera1254,370,906 - 54,397,483 (+)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1251,758,072 - 51,784,766 (+)NCBIHuRef
CHM1_11254,685,611 - 54,712,337 (+)NCBICHM1_1
Copz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.27134,409,523 - 134,435,661 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl7144,899,534 - 144,926,350 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.07144,900,050 - 144,926,299 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07142,680,779 - 142,706,987 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47142,184,081 - 142,209,955 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17142,264,119 - 142,289,000 (+)NCBI
Celera7130,835,003 - 130,860,877 (+)NCBICelera
Cytogenetic Map7q36NCBI
Copz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554581,568,968 - 1,595,026 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554581,569,077 - 1,592,851 (+)NCBIChiLan1.0ChiLan1.0
COPZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11235,117,991 - 35,145,050 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1235,117,991 - 35,145,050 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01234,392,373 - 34,419,119 (-)NCBIMhudiblu_PPA_v0panPan3
COPZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.127963,047 - 983,102 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2745,272,316 - 45,292,137 (+)NCBI
ROS_Cfam_1.027960,458 - 979,850 (-)NCBI
UMICH_Zoey_3.127978,807 - 998,914 (-)NCBI
UNSW_CanFamBas_1.027960,817 - 980,538 (-)NCBI
UU_Cfam_GSD_1.02745,676,211 - 45,695,959 (+)NCBI
Copz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494561,620,109 - 61,644,778 (-)NCBI
SpeTri2.0NW_00493651211,520,085 - 11,544,722 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COPZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl519,522,583 - 19,544,568 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1519,522,567 - 19,542,373 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2520,379,779 - 20,399,559 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COPZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11150,440,961 - 50,468,457 (+)NCBI
ChlSab1.1 Ensembl1150,441,026 - 50,467,199 (+)Ensembl
Vero_WHO_p1.0NW_023666037195,572,494 - 195,599,605 (-)NCBI
Copz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249042,351,010 - 2,374,284 (+)NCBI

Position Markers
RH124628  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815103,299,621 - 103,299,748UniSTSGRCm38
MGSCv3715103,130,052 - 103,130,179UniSTSGRCm37
Celera15105,462,473 - 105,462,600UniSTS
Cytogenetic Map15F3UniSTS
cM Map156.0UniSTS
RH125722  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815103,299,555 - 103,299,804UniSTSGRCm38
MGSCv3715103,129,986 - 103,130,235UniSTSGRCm37
Celera15105,462,407 - 105,462,656UniSTS
Cytogenetic Map15F3UniSTS
cM Map156.0UniSTS
Whitehead/MRC_RH15914.29UniSTS
BF406339  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815103,298,815 - 103,299,005UniSTSGRCm38
MGSCv3715103,129,246 - 103,129,436UniSTSGRCm37
Celera15105,461,667 - 105,461,857UniSTS
Cytogenetic Map15F3UniSTS
cM Map156.0UniSTS
RH127044  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F3UniSTS
cM Map156.0UniSTS
cM Map4 UniSTS
cM Map46.0UniSTS
cM Map15 UniSTS
Whitehead/MRC_RH4274.33UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578270103517472Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556323312103517472Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564434485103517472Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570461452104043685Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570465070104043685Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570465070104043685Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572498466104043685Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573545941104043685Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577629711104043685Mouse
14928306Manh79_mmandible shape 79 (mouse)1578949676104043685Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1579000000104043685Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579265530104043685Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined80011059104043685Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580415753104043685Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580987052104043685Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580987052104043685Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82717593104043685Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585988005104043685Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585988005104043685Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585988005104043685Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585993114104043685Mouse
1301764Chab4_mcholesterol absorption 4 (mouse)Not determined1586751919104043685Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92890759103517472Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:450
Count of miRNA genes:325
Interacting mature miRNAs:352
Transcripts:ENSMUST00000100162
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001357748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB037370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC164069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000100162   ⟹   ENSMUSP00000097738
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl15103,272,910 - 103,299,868 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229549   ⟹   ENSMUSP00000154922
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl15103,272,714 - 103,296,850 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230417
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl15103,272,901 - 103,295,163 (+)Ensembl
RefSeq Acc Id: ENSMUST00000230893   ⟹   ENSMUSP00000155674
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl15103,272,912 - 103,299,865 (+)Ensembl
RefSeq Acc Id: NM_001357748   ⟹   NP_001344677
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915103,181,315 - 103,208,292 (+)NCBI
GRCm3815103,272,888 - 103,299,865 (+)NCBI
Sequence:
RefSeq Acc Id: NM_019817   ⟹   NP_062791
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915103,181,315 - 103,208,292 (+)NCBI
GRCm3815103,272,888 - 103,299,865 (+)NCBI
MGSCv3715103,103,349 - 103,130,296 (+)RGD
Celera15105,435,330 - 105,462,717 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_004938859
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915103,181,261 - 103,208,295 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062791   ⟸   NM_019817
- Peptide Label: isoform 2
- UniProtKB: P61924 (UniProtKB/Swiss-Prot),   Q542M2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001344677   ⟸   NM_001357748
- Peptide Label: isoform 1
RefSeq Acc Id: ENSMUSP00000155674   ⟸   ENSMUST00000230893
RefSeq Acc Id: ENSMUSP00000097738   ⟸   ENSMUST00000100162
RefSeq Acc Id: ENSMUSP00000154922   ⟸   ENSMUST00000229549
Protein Domains
Clat_adaptor_s

Promoters
RGD ID:6825868
Promoter ID:MM_KWN:19900
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000100162,   UC007XXW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3615103,102,916 - 103,103,422 (+)MPROMDB
RGD ID:6825870
Promoter ID:MM_KWN:19902
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3
Transcripts:ENSMUST00000072242
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3615103,118,676 - 103,119,176 (+)MPROMDB
RGD ID:8685268
Promoter ID:EPDNEW_M20664
Type:multiple initiation site
Name:Copz1_1
Description:Mus musculus coatomer protein complex, subunit zeta 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3815103,272,901 - 103,272,961EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1929063 AgrOrtholog
Ensembl Genes ENSMUSG00000060992 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000097738 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000154922 UniProtKB/TrEMBL
  ENSMUSP00000155674 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000100162 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000229549 UniProtKB/TrEMBL
  ENSMUST00000230893 ENTREZGENE, UniProtKB/TrEMBL
InterPro AP_mu_sigma_su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Clathrin_sm-chain_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Coatomer_zeta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Longin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1929063 ENTREZGENE
NCBI Gene 56447 ENTREZGENE
PANTHER PTHR11043 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Clat_adaptor_s UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Copz1 PhenoGen
PROSITE CLAT_ADAPTOR_S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF64356 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VJV3_MOUSE UniProtKB/TrEMBL
  COPZ1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q542M2 ENTREZGENE, UniProtKB/TrEMBL
  Q8R3M1_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q9Y3C3 UniProtKB/Swiss-Prot