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Gene: Soat2 (sterol O-acyltransferase 2) Rattus norvegicus
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Symbol: Soat2
Name: sterol O-acyltransferase 2
Description: Exhibits sterol O-acyltransferase activity. Involved in cholesterol metabolic process and response to nutrient. Localizes to endoplasmic reticulum. Used to study end stage renal failure. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2); PARTICIPATES IN kidney failure pathway; steroid biosynthetic pathway; INTERACTS WITH ammonium chloride; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acat-2; acyl coenzyme A:cholesterol acyltransferase 2; acyl-CoA:cholesterol acyltransferase 2; acyl-coenzyme A:cholesterol acyltransferase 2; cholesterol acyltransferase 2
Orthologs:
Homo sapiens (human) : SOAT2 (sterol O-acyltransferase 2)  HGNC  Alliance
Mus musculus (house mouse) : Soat2 (sterol O-acyltransferase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Soat2 (sterol O-acyltransferase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SOAT2 (sterol O-acyltransferase 2)
Canis lupus familiaris (dog) : SOAT2 (sterol O-acyltransferase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Soat2 (sterol O-acyltransferase 2)
Sus scrofa (pig) : SOAT2 (sterol O-acyltransferase 2)
Chlorocebus sabaeus (African green monkey) : SOAT2 (sterol O-acyltransferase 2)
Heterocephalus glaber (naked mole-rat) : Soat2 (sterol O-acyltransferase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07143,754,892 - 143,767,989 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,754,892 - 143,767,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,552,394 - 141,565,491 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,890,902 - 140,903,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17140,967,338 - 140,980,436 (+)NCBI
Celera7129,716,600 - 129,729,697 (+)NCBICelera
Cytogenetic Map7q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Soat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628865
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.