(+)-catechin multiple interactions ISO RGD:731690 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of PLEC mRNA CTD PMID:24763279 1,1-dichloroethene increases expression ISO RGD:735905 6480464 vinylidene chloride results in increased expression of PLEC mRNA CTD PMID:26682919 1,2-dimethylhydrazine increases expression ISO RGD:735905 6480464 1, 2-Dimethylhydrazine results in increased expression of PLEC mRNA CTD PMID:22206623 17beta-estradiol decreases expression ISO RGD:731690 6480464 Estradiol results in decreased expression of PLEC mRNA CTD PMID:16705744 17beta-estradiol affects expression ISO RGD:731690 6480464 Estradiol affects the expression of PLEC mRNA CTD PMID:14699072 , PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735905 6480464 Tetrachlorodibenzodioxin results in increased expression of PLEC mRNA CTD PMID:17035482 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PLEC mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731690 6480464 Tetrachlorodibenzodioxin results in increased expression of PLEC mRNA CTD PMID:22903824 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735905 6480464 Tetrachlorodibenzodioxin affects the expression of PLEC mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PLEC mRNA, Tetrachlorodibenzodioxin results in decreased expression of PLEC protein CTD PMID:16548065 more ... 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of PLEC mRNA CTD PMID:21346803 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of PLEC protein CTD PMID:34915118 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731690 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PLEC mRNA more ... CTD PMID:28628672 4,4'-diaminodiphenylmethane decreases expression ISO RGD:735905 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of PLEC mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions ISO RGD:731690 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PLEC mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol increases methylation ISO RGD:735905 6480464 bis(4-hydroxyphenyl)sulfone results in increased methylation of PLEC promoter CTD PMID:33297965 4,4'-sulfonyldiphenol affects methylation ISO RGD:735905 6480464 bis(4-hydroxyphenyl)sulfone affects the methylation of PLEC exon, bis(4-hydroxyphenyl)sulfone affects the methylation of PLEC gene CTD PMID:31683443 , PMID:33297965 4-hydroxyphenyl retinamide increases expression ISO RGD:735905 6480464 Fenretinide results in increased expression of PLEC mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine decreases methylation ISO RGD:735905 6480464 Decitabine results in decreased methylation of PLEC gene CTD PMID:27923600 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of PLEC mRNA CTD PMID:24780913 acrolein multiple interactions ISO RGD:731690 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PLEC mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PLEC mRNA CTD PMID:32699268 adefovir pivoxil increases expression ISO RGD:731690 6480464 adefovir dipivoxil results in increased expression of PLEC mRNA CTD PMID:25596134 aflatoxin B1 increases expression ISO RGD:735905 6480464 Aflatoxin B1 results in increased expression of PLEC mRNA CTD PMID:19770486 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of PLEC mRNA CTD PMID:33354967 Aflatoxin B2 alpha decreases methylation ISO RGD:731690 6480464 aflatoxin B2 results in decreased methylation of PLEC polyA tail CTD PMID:30157460 all-trans-retinoic acid decreases expression ISO RGD:731690 6480464 Tretinoin results in decreased expression of PLEC mRNA CTD PMID:23830798 alpha-pinene multiple interactions ISO RGD:731690 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PLEC mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of PLEC mRNA CTD PMID:32699268 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PLEC mRNA CTD PMID:16483693 aristolochic acid A increases expression ISO RGD:731690 6480464 aristolochic acid I results in increased expression of PLEC mRNA CTD PMID:33212167 arsane increases expression ISO RGD:731690 6480464 Arsenic results in increased expression of PLEC protein CTD PMID:19818359 arsane affects methylation ISO RGD:731690 6480464 Arsenic affects the methylation of PLEC gene CTD PMID:25304211 arsenic atom increases expression ISO RGD:731690 6480464 Arsenic results in increased expression of PLEC protein CTD PMID:19818359 arsenic atom affects methylation ISO RGD:731690 6480464 Arsenic affects the methylation of PLEC gene CTD PMID:25304211 arsenite(3-) multiple interactions ISO RGD:731690 6480464 arsenite inhibits the reaction [G3BP1 protein binds to PLEC mRNA], arsenite promotes the reaction [G3BP1 protein binds to PLEC protein] CTD PMID:32406909 benzo[a]pyrene multiple interactions ISO RGD:735905 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PLEC promoter] CTD PMID:19654925 benzo[a]pyrene increases methylation ISO RGD:731690 6480464 Benzo(a)pyrene results in increased methylation of PLEC exon, Benzo(a)pyrene results in increased methylation of PLEC promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:731690 6480464 [Soot co-treated with Benzo(a)pyrene] results in increased expression of PLEC protein CTD PMID:24464499 benzo[a]pyrene decreases expression ISO RGD:731690 6480464 Benzo(a)pyrene results in decreased expression of PLEC protein CTD PMID:32717239 benzo[a]pyrene increases expression ISO RGD:735905 6480464 Benzo(a)pyrene results in increased expression of PLEC mRNA CTD PMID:19770486 , PMID:22228805 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:731690 6480464 7 more ... CTD PMID:19150397 , PMID:20018196 benzo[b]fluoranthene increases expression ISO RGD:735905 6480464 benzo(b)fluoranthene results in increased expression of PLEC mRNA CTD PMID:26377693 bis(2-chloroethyl) sulfide increases phosphorylation ISO RGD:731690 6480464 Mustard Gas results in increased phosphorylation of PLEC protein CTD PMID:19845377 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PLEC mRNA CTD PMID:25181051 bisphenol A affects expression ISO RGD:731690 6480464 bisphenol A affects the expression of PLEC protein CTD PMID:34186270 bisphenol A increases expression ISO RGD:735905 6480464 bisphenol A results in increased expression of PLEC mRNA CTD PMID:33221593 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PLEC mRNA CTD PMID:30816183 , PMID:34947998 bisphenol A multiple interactions ISO RGD:731690 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PLEC gene, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PLEC mRNA CTD PMID:28628672 , PMID:31601247 Bisphenol B increases expression ISO RGD:731690 6480464 bisphenol B results in increased expression of PLEC protein CTD PMID:34186270 bisphenol F multiple interactions ISO RGD:731690 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of PLEC mRNA CTD PMID:28628672 bisphenol F increases expression ISO RGD:731690 6480464 bisphenol F results in increased expression of PLEC protein CTD PMID:34186270 butan-1-ol multiple interactions ISO RGD:731690 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of PLEC mRNA CTD PMID:29432896 cadmium atom multiple interactions ISO RGD:731690 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PLEC mRNA CTD PMID:35301059 cadmium dichloride decreases expression ISO RGD:731690 6480464 Cadmium Chloride results in decreased expression of PLEC mRNA CTD PMID:25596134 cadmium dichloride multiple interactions ISO RGD:731690 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PLEC mRNA CTD PMID:35301059 caffeine decreases expression ISO RGD:731690 6480464 Caffeine results in decreased expression of PLEC protein CTD PMID:31195006 caffeine affects phosphorylation ISO RGD:731690 6480464 Caffeine affects the phosphorylation of PLEC protein CTD PMID:35688186 cannabidiol decreases expression ISO RGD:731690 6480464 Cannabidiol results in decreased expression of PLEC protein CTD PMID:34122009 chloroacetaldehyde affects expression ISO RGD:731690 6480464 chloroacetaldehyde affects the expression of PLEC mRNA CTD PMID:25596134 cidofovir anhydrous decreases expression ISO RGD:731690 6480464 Cidofovir results in decreased expression of PLEC mRNA CTD PMID:25596134 cisplatin affects expression ISO RGD:731690 6480464 Cisplatin affects the expression of PLEC mRNA CTD PMID:25596134 cisplatin decreases expression ISO RGD:731690 6480464 Cisplatin results in decreased expression of PLEC mRNA CTD PMID:27392435 clodronic acid decreases expression ISO RGD:731690 6480464 Clodronic Acid results in decreased expression of PLEC mRNA CTD PMID:25596134 cocaine affects expression EXP 6480464 Cocaine affects the expression of PLEC mRNA CTD PMID:20187946 copper(II) sulfate increases expression ISO RGD:731690 6480464 Copper Sulfate results in increased expression of PLEC mRNA CTD PMID:19549813 coumarin affects phosphorylation ISO RGD:731690 6480464 coumarin affects the phosphorylation of PLEC protein CTD PMID:35688186 crocidolite asbestos increases expression ISO RGD:731690 6480464 Asbestos, Crocidolite results in increased expression of PLEC protein CTD PMID:29553831 cyclosporin A increases expression ISO RGD:731690 6480464 Cyclosporine results in increased expression of PLEC mRNA CTD PMID:25562108 cyclosporin A decreases methylation ISO RGD:731690 6480464 Cyclosporine results in decreased methylation of PLEC promoter CTD PMID:27989131 deoxynivalenol decreases phosphorylation ISO RGD:735905 6480464 deoxynivalenol results in decreased phosphorylation of PLEC protein CTD PMID:23811945 deoxynivalenol affects phosphorylation ISO RGD:735905 6480464 deoxynivalenol affects the phosphorylation of PLEC protein CTD PMID:23352502 dexamethasone multiple interactions ISO RGD:731690 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PLEC mRNA more ... CTD PMID:28628672 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of PLEC mRNA CTD PMID:18636392 dicrotophos increases expression ISO RGD:731690 6480464 dicrotophos results in increased expression of PLEC mRNA CTD PMID:28302478 dioxygen increases expression ISO RGD:731690 6480464 Oxygen deficiency results in increased expression of PLEC mRNA CTD PMID:25596134 disodium selenite increases expression ISO RGD:731690 6480464 Sodium Selenite results in increased expression of PLEC mRNA CTD PMID:18175754 doxorubicin affects expression ISO RGD:731690 6480464 Doxorubicin affects the expression of PLEC protein CTD PMID:29385562 doxorubicin decreases expression ISO RGD:731690 6480464 Doxorubicin results in decreased expression of PLEC mRNA CTD PMID:29803840 elemental selenium increases expression ISO RGD:731690 6480464 Selenium results in increased expression of PLEC mRNA CTD PMID:19244175 epoxiconazole decreases expression ISO RGD:735905 6480464 epoxiconazole results in decreased expression of PLEC mRNA CTD PMID:35436446 ethanol increases expression ISO RGD:735905 6480464 Ethanol results in increased expression of PLEC mRNA CTD PMID:30319688 fenthion decreases expression ISO RGD:735905 6480464 Fenthion results in decreased expression of PLEC mRNA CTD PMID:34813904 finasteride increases expression EXP 6480464 Finasteride results in increased expression of PLEC mRNA CTD PMID:24136188 fluoxetine decreases expression EXP 6480464 Fluoxetine results in decreased expression of PLEC mRNA CTD PMID:21852994 fulvestrant increases methylation ISO RGD:731690 6480464 Fulvestrant results in increased methylation of PLEC gene CTD PMID:31601247 fulvestrant multiple interactions ISO RGD:731690 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PLEC gene CTD PMID:31601247 genistein decreases expression ISO RGD:731690 6480464 Genistein results in decreased expression of PLEC mRNA CTD PMID:16705744 genistein decreases expression ISO RGD:735905 6480464 Genistein results in decreased expression of PLEC mRNA CTD PMID:22553218 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of PLEC mRNA CTD PMID:33387578 glyphosate decreases methylation EXP 6480464 glyphosate results in decreased methylation of PLEC gene CTD PMID:31011160 hexadecanoic acid decreases phosphorylation ISO RGD:731690 6480464 Palmitic Acid results in decreased phosphorylation of PLEC protein CTD PMID:28073184 hydrogen peroxide increases expression ISO RGD:731690 6480464 Hydrogen Peroxide results in increased expression of PLEC mRNA CTD PMID:18951874 hydrogen peroxide multiple interactions ISO RGD:735905 6480464 N-(oxo-5 more ... CTD PMID:31494107 ibuprofen increases expression ISO RGD:731690 6480464 Ibuprofen results in increased expression of PLEC mRNA CTD PMID:18351690 ibuprofen affects expression ISO RGD:731690 6480464 Ibuprofen affects the expression of PLEC protein CTD PMID:18351690 indometacin multiple interactions ISO RGD:731690 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of PLEC mRNA more ... CTD PMID:28628672 isobutanol multiple interactions ISO RGD:731690 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of PLEC mRNA CTD PMID:29432896 ivermectin decreases expression ISO RGD:731690 6480464 Ivermectin results in decreased expression of PLEC protein CTD PMID:32959892 lead(0) affects expression ISO RGD:731690 6480464 Lead affects the expression of PLEC mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:731690 6480464 Lead affects the expression of PLEC mRNA CTD PMID:28903495 methamphetamine increases expression ISO RGD:735905 6480464 Methamphetamine results in increased expression of PLEC mRNA CTD PMID:26307267 methidathion affects expression ISO RGD:735905 6480464 methidathion affects the expression of PLEC mRNA CTD PMID:34813904 N-nitrosodiethylamine multiple interactions ISO RGD:735905 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PLEC gene CTD PMID:23968726 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of PLEC protein CTD PMID:19716841 nickel sulfate increases expression ISO RGD:731690 6480464 nickel sulfate results in increased expression of PLEC mRNA CTD PMID:18651567 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of PLEC mRNA CTD PMID:18636392 ozone multiple interactions ISO RGD:731690 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of PLEC mRNA more ... CTD PMID:32699268 paracetamol decreases expression ISO RGD:731690 6480464 Acetaminophen results in decreased expression of PLEC mRNA CTD PMID:21420995 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of PLEC mRNA CTD PMID:33387578 phenytoin increases expression EXP 6480464 Phenytoin results in increased expression of PLEC mRNA CTD PMID:20345932 piperonyl butoxide multiple interactions ISO RGD:735905 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of PLEC gene CTD PMID:23968726 progesterone decreases expression ISO RGD:731690 6480464 Progesterone results in decreased expression of PLEC mRNA CTD PMID:18037150 , PMID:18070364 propiconazole decreases expression ISO RGD:735905 6480464 propiconazole results in decreased expression of PLEC mRNA CTD PMID:21278054 quercetin increases expression ISO RGD:731690 6480464 Quercetin results in increased expression of PLEC protein CTD PMID:14750173 quercetin increases phosphorylation ISO RGD:731690 6480464 Quercetin results in increased phosphorylation of PLEC protein CTD PMID:35688186 resveratrol decreases expression ISO RGD:735905 6480464 resveratrol results in decreased expression of PLEC protein CTD PMID:25505154 selenium atom increases expression ISO RGD:731690 6480464 Selenium results in increased expression of PLEC mRNA CTD PMID:19244175 silicon dioxide affects secretion ISO RGD:731690 6480464 Silicon Dioxide analog affects the secretion of PLEC protein CTD PMID:25895662 sodium arsenite increases expression ISO RGD:731690 6480464 sodium arsenite results in increased expression of PLEC mRNA CTD PMID:34032870 sodium arsenite multiple interactions ISO RGD:731690 6480464 sodium arsenite promotes the reaction [PLEC protein binds to CAPRIN1 protein] CTD PMID:33939924 sulindac increases expression EXP 6480464 Sulindac results in increased expression of PLEC mRNA CTD PMID:24136188 tamoxifen affects expression ISO RGD:731690 6480464 Tamoxifen affects the expression of PLEC mRNA CTD PMID:14699072 thapsigargin decreases expression EXP 6480464 Thapsigargin results in decreased expression of PLEC protein CTD PMID:35544339 titanium dioxide decreases expression ISO RGD:731690 6480464 titanium dioxide results in decreased expression of PLEC protein CTD PMID:30910687 titanium dioxide decreases methylation ISO RGD:731690 6480464 titanium dioxide results in decreased methylation of PLEC promoter CTD PMID:34973136 titanium dioxide increases expression ISO RGD:735905 6480464 titanium dioxide results in increased expression of PLEC mRNA CTD PMID:29264374 Tributyltin oxide increases expression ISO RGD:735905 6480464 bis(tri-n-butyltin)oxide results in increased expression of PLEC protein CTD PMID:19552622 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of PLEC mRNA CTD PMID:33387578 triclosan increases methylation ISO RGD:731690 6480464 Triclosan results in increased methylation of PLEC gene CTD PMID:34523531 Triptolide increases expression ISO RGD:735905 6480464 triptolide results in increased expression of PLEC mRNA CTD PMID:32835833 triptonide increases expression ISO RGD:735905 6480464 triptonide results in increased expression of PLEC mRNA CTD PMID:33045310 troglitazone increases expression ISO RGD:731690 6480464 troglitazone results in increased expression of PLEC mRNA CTD PMID:19140230 urethane increases expression ISO RGD:731690 6480464 Urethane results in increased expression of PLEC mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:731690 6480464 Valproic Acid results in increased methylation of PLEC gene CTD PMID:29154799 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of PLEC mRNA CTD PMID:29427782 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of PLEC mRNA CTD PMID:29427782 vancomycin decreases expression ISO RGD:735905 6480464 Vancomycin results in decreased expression of PLEC mRNA CTD PMID:18930951 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of PLEC mRNA CTD PMID:23034163 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of PLEC gene CTD PMID:31079544 zoledronic acid decreases expression ISO RGD:731690 6480464 zoledronic acid results in decreased expression of PLEC mRNA, zoledronic acid results in decreased expression of PLEC protein CTD PMID:25596134 , PMID:28871336