Tmem186l1 (transmembrane protein 186l1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Tmem186l1 (transmembrane protein 186l1) Rattus norvegicus
Analyze
Symbol: Tmem186l1
Name: transmembrane protein 186l1
RGD ID: 1306282
Description: Predicted to be located in mitochondrial inner membrane; INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC314858; RGD1306282; similar to RIKEN cDNA 4432406C05; transmembrane protein 186-like
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,439,204 - 55,441,385 (-)NCBIGRCr8
mRatBN7.2753,553,378 - 53,570,587 (-)NCBImRatBN7.2mRatBN7.2
Rnor_6.0760,987,516 - 61,004,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0760,986,153 - 61,003,359 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4757,262,629 - 57,335,250 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1757,283,358 - 57,348,756 (-)NCBI
Celera750,323,079 - 50,340,281 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Tmem186l1
38 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:76
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000038294
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat

Markers in Region
D7Rat73  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2753,612,714 - 53,612,950 (+)MAPPERmRatBN7.2
Rnor_6.0761,047,589 - 61,047,824NCBIRnor6.0
Rnor_5.0761,044,919 - 61,045,154UniSTSRnor5.0
RGSC_v3.4757,326,197 - 57,326,432UniSTSRGSC3.4
RGSC_v3.4757,326,196 - 57,326,584RGDRGSC3.4
RGSC_v3.1757,346,927 - 57,347,162RGD
Celera750,381,645 - 50,381,880UniSTS
RH 3.4 Map7487.7RGD
RH 3.4 Map7487.7UniSTS
RH 2.0 Map7413.2RGD
SHRSP x BN Map733.28RGD
FHH x ACI Map732.32RGD
Cytogenetic Map7q22UniSTS
D7Rat146  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2753,616,917 - 53,617,069 (+)MAPPERmRatBN7.2
Rnor_6.0761,052,123 - 61,052,274NCBIRnor6.0
Rnor_5.0761,049,453 - 61,049,604UniSTSRnor5.0
RGSC_v3.4757,330,399 - 57,330,551RGDRGSC3.4
RGSC_v3.4757,330,400 - 57,330,551UniSTSRGSC3.4
RGSC_v3.1757,351,130 - 57,351,281RGD
Celera750,385,848 - 50,386,001UniSTS
RH 3.4 Map7482.1RGD
RH 3.4 Map7482.1UniSTS
RH 2.0 Map7415.8RGD
SHRSP x BN Map733.28RGD
Cytogenetic Map7q22UniSTS


Expression


Sequence


RefSeq Acc Id: XM_063264462   ⟹   XP_063120532
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,439,204 - 55,441,385 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063120532 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_063120532   ⟸   XM_063264462


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-33963 BioCyc
NCBI Gene 314858 ENTREZGENE
PhenoGen Tmem186l1 PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Tmem186l1  transmembrane protein 186l1  RGD1306282  similar to RIKEN cDNA 4432406C05  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1306282  similar to RIKEN cDNA 4432406C05   RGD1306282_predicted  similar to RIKEN cDNA 4432406C05 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1306282_predicted  similar to RIKEN cDNA 4432406C05 (predicted)  LOC314858_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314858_predicted  similar to RIKEN cDNA 4432406C05 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL