Rab3ip (RAB3A interacting protein) - Rat Genome Database

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Gene: Rab3ip (RAB3A interacting protein) Rattus norvegicus
Analyze
Symbol: Rab3ip
Name: RAB3A interacting protein
RGD ID: 620650
Description: Enables GTPase binding activity and guanyl-nucleotide exchange factor activity. Involved in negative regulation of filopodium assembly. Located in cytosol; perinuclear region of cytoplasm; and proximal dendrite. Colocalizes with Golgi apparatus. Orthologous to human RAB3IP (RAB3A interacting protein); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: rab-3A-interacting protein; RAB3A interacting protein (rabin3); RAB3A-interacting protein; rabin 3; rabin-3; RABIN3; SSX2-interacting protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2752,531,461 - 52,575,295 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl752,532,401 - 52,561,043 (-)Ensembl
Rnor_6.0759,927,486 - 59,971,518 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,928,426 - 59,957,232 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,932,332 - 59,976,359 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,229,363 - 56,258,007 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1756,250,358 - 56,278,708 (-)NCBI
Celera749,308,208 - 49,336,852 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A. Brondyk WH, etal., Mol Cell Biol 1995 Mar;15(3):1137-43.
2. NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15. Chiba S, etal., EMBO J. 2013 Mar 20;32(6):874-85. doi: 10.1038/emboj.2013.32. Epub 2013 Feb 22.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport. Hattula K, etal., Mol Biol Cell. 2002 Sep;13(9):3268-80.
5. Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation. Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Ultanir SK, etal., Neuron. 2012 Mar 22;73(6):1127-42. doi: 10.1016/j.neuron.2012.01.019. Epub 2012 Mar 21.
Additional References at PubMed
PMID:10580117   PMID:10602480   PMID:12007189   PMID:12477932   PMID:17574030   PMID:20937701   PMID:23382462   PMID:26258637  


Genomics

Comparative Map Data
Rab3ip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2752,531,461 - 52,575,295 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl752,532,401 - 52,561,043 (-)Ensembl
Rnor_6.0759,927,486 - 59,971,518 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,928,426 - 59,957,232 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,932,332 - 59,976,359 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,229,363 - 56,258,007 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1756,250,358 - 56,278,708 (-)NCBI
Celera749,308,208 - 49,336,852 (-)NCBICelera
Cytogenetic Map7q22NCBI
RAB3IP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381269,738,242 - 69,823,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1269,738,860 - 69,823,204 (+)EnsemblGRCh38hg38GRCh38
GRCh371270,132,640 - 70,216,984 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361268,418,898 - 68,503,251 (+)NCBINCBI36hg18NCBI36
Build 341268,419,454 - 68,495,770NCBI
Celera1269,796,326 - 69,880,688 (+)NCBI
Cytogenetic Map12q15NCBI
HuRef1267,181,822 - 67,267,191 (+)NCBIHuRef
CHM1_11270,100,838 - 70,185,226 (+)NCBICHM1_1
T2T-CHM13v2.01269,717,994 - 69,802,330 (+)NCBI
Rab3ip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,741,685 - 116,786,361 (-)NCBIGRCm39mm39
GRCm39 Ensembl10116,741,689 - 116,786,674 (-)Ensembl
GRCm3810116,905,780 - 116,950,456 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10116,905,784 - 116,950,769 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710116,342,840 - 116,387,436 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610116,309,894 - 116,354,490 (-)NCBImm8
Celera10118,848,689 - 118,893,539 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1064.96NCBI
Rab3ip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540510,031,666 - 10,090,456 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540510,031,333 - 10,091,438 (+)NCBIChiLan1.0ChiLan1.0
RAB3IP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11270,035,629 - 70,107,689 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1270,035,629 - 70,107,689 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01267,265,922 - 67,344,241 (+)NCBIMhudiblu_PPA_v0panPan3
RAB3IP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11011,673,749 - 11,714,282 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1011,673,777 - 11,714,281 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1011,604,813 - 11,645,346 (+)NCBI
ROS_Cfam_1.01011,797,196 - 11,837,976 (+)NCBI
ROS_Cfam_1.0 Ensembl1011,797,167 - 11,839,204 (+)Ensembl
UMICH_Zoey_3.11011,663,957 - 11,704,723 (+)NCBI
UNSW_CanFamBas_1.01011,911,509 - 11,952,195 (+)NCBI
UU_Cfam_GSD_1.01012,034,352 - 12,075,134 (+)NCBI
LOC101961543
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,499,946 - 46,551,861 (-)NCBI
SpeTri2.0NW_0049365457,558,256 - 7,610,178 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB3IP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1534,002,792 - 34,053,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2536,601,756 - 36,652,151 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103238704
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,370,960 - 65,435,097 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1165,371,044 - 65,434,820 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037180,255,380 - 180,321,086 (-)NCBIVero_WHO_p1.0
Rab3ip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475028,015,282 - 28,085,045 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475028,014,245 - 28,085,967 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH131429  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,532,420 - 52,532,631 (+)MAPPERmRatBN7.2
Rnor_6.0759,928,446 - 59,928,656NCBIRnor6.0
Rnor_5.0759,933,292 - 59,933,502UniSTSRnor5.0
RGSC_v3.4756,229,385 - 56,229,595UniSTSRGSC3.4
Celera749,308,230 - 49,308,440UniSTS
RH 3.4 Map7483.0UniSTS
Cytogenetic Map7q22UniSTS
RH131529  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2752,545,293 - 52,545,508 (+)MAPPERmRatBN7.2
Rnor_6.0759,941,319 - 59,941,533NCBIRnor6.0
Rnor_5.0759,946,165 - 59,946,379UniSTSRnor5.0
RGSC_v3.4756,242,258 - 56,242,472UniSTSRGSC3.4
Celera749,321,103 - 49,321,317UniSTS
RH 3.4 Map7480.4UniSTS
Cytogenetic Map7q22UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:150
Interacting mature miRNAs:173
Transcripts:ENSRNOT00000007258
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 52 41 19 41 74 35 41 11
Low 7 5 8 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007258   ⟹   ENSRNOP00000007258
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,532,401 - 52,561,043 (-)Ensembl
Rnor_6.0 Ensembl759,928,426 - 59,957,232 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081599   ⟹   ENSRNOP00000071773
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,533,012 - 52,561,043 (-)Ensembl
Rnor_6.0 Ensembl759,928,867 - 59,957,228 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109052   ⟹   ENSRNOP00000079240
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,532,401 - 52,561,043 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118552   ⟹   ENSRNOP00000091358
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,532,401 - 52,561,043 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118928   ⟹   ENSRNOP00000076496
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl752,534,087 - 52,561,043 (-)Ensembl
RefSeq Acc Id: NM_017313   ⟹   NP_059009
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,532,399 - 52,561,043 (-)NCBI
Rnor_6.0759,928,424 - 59,957,232 (-)NCBI
Rnor_5.0759,932,332 - 59,976,359 (-)NCBI
RGSC_v3.4756,229,363 - 56,258,007 (-)RGD
Celera749,308,208 - 49,336,852 (-)RGD
Sequence:
RefSeq Acc Id: XM_006241357   ⟹   XP_006241419
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,575,295 (-)NCBI
Rnor_6.0759,927,486 - 59,971,517 (-)NCBI
Rnor_5.0759,932,332 - 59,976,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241360   ⟹   XP_006241422
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,575,295 (-)NCBI
Rnor_6.0759,927,486 - 59,971,517 (-)NCBI
Rnor_5.0759,932,332 - 59,976,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765383   ⟹   XP_008763605
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,559,156 (-)NCBI
Rnor_6.0759,927,486 - 59,955,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594704   ⟹   XP_017450193
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,575,295 (-)NCBI
Rnor_6.0759,927,486 - 59,971,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039078618   ⟹   XP_038934546
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,575,295 (-)NCBI
RefSeq Acc Id: XM_039078619   ⟹   XP_038934547
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,575,289 (-)NCBI
RefSeq Acc Id: XM_039078620   ⟹   XP_038934548
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2752,531,461 - 52,542,669 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_059009   ⟸   NM_017313
- UniProtKB: A1L127 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241422   ⟸   XM_006241360
- Peptide Label: isoform X1
- UniProtKB: A1L127 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241419   ⟸   XM_006241357
- Peptide Label: isoform X1
- UniProtKB: A1L127 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763605   ⟸   XM_008765383
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017450193   ⟸   XM_017594704
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000071773   ⟸   ENSRNOT00000081599
RefSeq Acc Id: ENSRNOP00000007258   ⟸   ENSRNOT00000007258
RefSeq Acc Id: XP_038934546   ⟸   XM_039078618
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038934547   ⟸   XM_039078619
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038934548   ⟸   XM_039078620
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000076496   ⟸   ENSRNOT00000118928
RefSeq Acc Id: ENSRNOP00000091358   ⟸   ENSRNOT00000118552
RefSeq Acc Id: ENSRNOP00000079240   ⟸   ENSRNOT00000109052
Protein Domains
Sec2p

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62739-F1-model_v2 AlphaFold Q62739 1-460 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 59951202 59951203 A G snv FHH/EurMcwi (MCW), WN/N (2020), SBN/Ygl (MCW), SS/JrHsdMcwi (MCW), Buf/N (MCW), WN/N (MCW), BBDP/Wor (RGD), FHH/EurMcwi (RGD), FHL/EurMcwi (RGD), LEW/Crl (RGD), LEW/NCrlBR (RGD), SBN/Ygl (RGD), SS/Jr (RGD), SS/JrHsdMcwi (RGD), BUF/N (2020), FHH/EurMcwi (2019), LEW/Crl (2019), SS/JrHsdMcwi (2019), FHL/EurMcwi (MCW)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
7 52555016 52555017 A G snv BUF/N (2020), FHH/EurMcwi (2019), WN/N (2020), SS/JrHsdMcwi (2019), LEW/Crl (2019)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620650 AgrOrtholog
BioCyc Gene G2FUF-34026 BioCyc
Ensembl Genes ENSRNOG00000005362 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000007258 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000071773.1 UniProtKB/TrEMBL
  ENSRNOP00000076496.1 UniProtKB/TrEMBL
  ENSRNOP00000079240 ENTREZGENE
  ENSRNOP00000079240.1 UniProtKB/TrEMBL
  ENSRNOP00000091358 ENTREZGENE
  ENSRNOP00000091358.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007258 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000081599.2 UniProtKB/TrEMBL
  ENSRNOT00000109052 ENTREZGENE
  ENSRNOT00000109052.1 UniProtKB/TrEMBL
  ENSRNOT00000118552 ENTREZGENE
  ENSRNOT00000118552.1 UniProtKB/TrEMBL
  ENSRNOT00000118928.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7457420 IMAGE-MGC_LOAD
InterPro RAB3IL/RAB3IP/Sec2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29885 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156662 IMAGE-MGC_LOAD
NCBI Gene 29885 ENTREZGENE
PANTHER PTHR14430 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sec2p UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rab3ip PhenoGen
UniProt A0A0G2K1B4_RAT UniProtKB/TrEMBL
  A0A8I5YBC2_RAT UniProtKB/TrEMBL
  A0A8I5ZML7_RAT UniProtKB/TrEMBL
  A0A8I6AR50_RAT UniProtKB/TrEMBL
  A1L127 ENTREZGENE
  Q62739 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A1L127 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-31 Rab3ip  RAB3A interacting protein  Rab3ip  RAB3A interacting protein (rabin3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Rab3ip  RAB3A interacting protein (rabin3)  Rab3ip  RAB3A interacting protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Rab3ip  RAB3A interacting protein  RABIN3  rabin 3  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains a coiled coil domain and a region with similarity to S. cerevisiae Sec2p 633748
gene_expression abundantly expressed in testes 633748