Nedd1 (NEDD1 gamma-tubulin ring complex targeting factor)

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Gene: Nedd1 (NEDD1 gamma-tubulin ring complex targeting factor) Rattus norvegicus

Analyze

Symbol:

Nedd1

Name:

NEDD1 gamma-tubulin ring complex targeting factor

RGD ID:

1307750

Description:

Predicted to enable gamma-tubulin binding activity. Predicted to be involved in microtubule nucleation and mitotic cell cycle. Predicted to be located in several cellular components, including apical part of cell; centrosome; and nuclear lumen. Predicted to be active in microtubule cytoskeleton. Orthologous to human NEDD1 (NEDD1 gamma-tubulin ring complex targeting factor); INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; aflatoxin B1.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC299730; neural precursor cell expressed, developmentally down-regulated 1; neural precursor cell expressed, developmentally down-regulated gene 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	27,233,050 - 27,274,486 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	27,233,316 - 27,274,486 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	29,227,389 - 29,268,826 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	31,389,742 - 31,431,181 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	31,157,130 - 31,202,370 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	33,544,097 - 33,584,406 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	33,543,828 - 33,584,564 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	33,615,235 - 33,655,544 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	29,704,249 - 29,745,416 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	29,724,518 - 29,773,468 (-)	NCBI
Celera	7	24,340,948 - 24,381,914 (-)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (EXP,ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

bortezomib (ISO)

caffeine (ISO)

carbamazepine (ISO)

choline (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

diarsenic trioxide (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hydralazine (ISO)

L-methionine (ISO)

methimazole (EXP)

methyl methanesulfonate (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

tamoxifen (ISO)

tetrachloroethene (ISO)

thioacetamide (EXP)

topotecan (EXP)

triptonide (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule nucleation (IBA)

mitotic cell cycle (IBA)

Cellular Component

apical part of cell (ISO)

centriole (IBA,ISO)

centrosome (ISO)

ciliary basal body (IBA,ISO)

cytoplasm (ISO)

cytosol (IEA,ISO)

fibrillar center (IEA,ISO)

nucleoplasm (IEA,ISO)

pericentriolar material (IBA,ISO)

spindle pole (IBA,ISO)

Molecular Function

gamma-tubulin binding (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18239929	PMID:21399614	PMID:27137183

Genomics

Comparative Map Data

Nedd1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	27,233,050 - 27,274,486 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	27,233,316 - 27,274,486 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	29,227,389 - 29,268,826 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	31,389,742 - 31,431,181 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	31,157,130 - 31,202,370 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	33,544,097 - 33,584,406 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	33,543,828 - 33,584,564 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	33,615,235 - 33,655,544 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	29,704,249 - 29,745,416 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	29,724,518 - 29,773,468 (-)	NCBI
Celera	7	24,340,948 - 24,381,914 (-)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

NEDD1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	96,907,257 - 96,953,780 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	96,907,224 - 96,953,780 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	97,301,035 - 97,347,558 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	95,825,375 - 95,870,172 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	95,803,711 - 95,848,507	NCBI
Celera	12	96,967,004 - 97,013,462 (+)	NCBI		Celera
Cytogenetic Map	12	q23.1	NCBI
HuRef	12	94,363,760 - 94,410,169 (+)	NCBI		HuRef
CHM1_1	12	97,265,952 - 97,312,431 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	96,881,012 - 96,927,469 (+)	NCBI		T2T-CHM13v2.0

Nedd1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	92,520,607 - 92,559,544 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	92,520,608 - 92,558,282 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	92,684,745 - 92,722,418 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	92,684,746 - 92,722,420 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	92,147,490 - 92,185,163 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	92,114,545 - 92,152,159 (-)	NCBI		MGSCv36	mm8
Celera	10	94,676,340 - 94,714,125 (-)	NCBI		Celera
Cytogenetic Map	10	C2	NCBI
cM Map	10	47.25	NCBI

Nedd1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	33,058,839 - 33,112,358 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955405	33,066,734 - 33,109,750 (+)	NCBI	ChiLan1.0	ChiLan1.0

NEDD1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	104,975,439 - 105,053,206 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	94,497,203 - 94,543,412 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	97,914,112 - 97,959,953 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	97,914,112 - 97,959,945 (+)	Ensembl	panpan1.1		panPan2

NEDD1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	36,542,218 - 36,589,380 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	36,542,152 - 36,587,758 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	36,926,673 - 36,973,707 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	37,206,756 - 37,253,864 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	37,205,935 - 37,253,850 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	36,478,601 - 36,525,635 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	36,572,344 - 36,619,417 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	36,843,539 - 36,890,793 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101957471
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	52,940,558 - 52,946,286 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936677	2,954,738 - 2,963,072 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NEDD1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	86,693,843 - 86,737,222 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	86,693,802 - 86,737,259 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	91,290,874 - 91,316,139 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NEDD1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	92,256,975 - 92,301,430 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	92,259,578 - 92,301,605 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	152,798,574 - 152,843,034 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nedd1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	10,498,365 - 10,541,081 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624750	10,497,362 - 10,542,732 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nedd1
607 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	453
Count of miRNA genes:	248
Interacting mature miRNAs:	305
Transcripts:	ENSRNOT00000005463
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	27829089	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	31962314	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	31962314	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34000259	Rat
2317047	Wbc4	White blood cell count QTL 4		0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	7	1	35342956	Rat
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	44782185	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1	44822433	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
10755438	Coatc9	Coat color QTL 9		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	3529280	48529280	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	5329019	50329019	Rat
10755440	Coatc10	Coat color QTL 10		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	7496499	52496499	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	7573985	52573985	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	9462246	58265113	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	9462246	98011544	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	9866467	60460686	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	15573889	60573889	Rat
1582260	Bw72	Body weight QTL 72	3.2	0.0043	body mass (VT:0001259)	body weight (CMO:0000012)	7	15795565	38073970	Rat
1582261	Bw69	Body weight QTL 69	3.2	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	7	15795565	38073970	Rat
1582262	Bw75	Body weight QTL 75	3	0.0038	body mass (VT:0001259)	body weight (CMO:0000012)	7	15795565	38073970	Rat
2317059	Aia15	Adjuvant induced arthritis QTL 15	2.46		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	7	17004598	62004598	Rat
10755451	Coatc11	Coat color QTL 11		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	17944357	62944357	Rat
61369	Mcs2	Mammary carcinoma susceptibility QTL 2	3.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	19032807	35526300	Rat
1354637	Scl30	Serum cholesterol level QTL 30	3.7		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	7	19654317	49753746	Rat
1354644	Spl4	Serum phospholipid level QTL 4	4.9		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	7	19654317	49753746	Rat
1354639	Spl5	Serum phospholipid level QTL 5	3.9		blood LDL phospholipid amount (VT:0010505)	blood low density lipoprotein phospholipid level (CMO:0001568)	7	19654317	52888450	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	19654317	84928080	Rat
2290372	Gluco33	Glucose level QTL 33	2.71		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	20555705	29891047	Rat
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	21921195	66921195	Rat
1641885	Alcrsp9	Alcohol response QTL 9			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	7	24099606	69099606	Rat
1549840	Bss5	Bone structure and strength QTL 5	9.8		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	7	24751841	69751841	Rat
70190	Mcs6	Mammary carcinoma susceptibility QTL 6	2.29		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	26737401	63902784	Rat

Markers in Region

RH143697

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	27,234,709 - 27,234,827 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	33,545,491 - 33,545,608	NCBI	Rnor6.0
Rnor_5.0	7	33,616,629 - 33,616,746	UniSTS	Rnor5.0
RGSC_v3.4	7	29,705,643 - 29,705,760	UniSTS	RGSC3.4
Celera	7	24,342,342 - 24,342,459	UniSTS
RH 3.4 Map	7	179.9	UniSTS
Cytogenetic Map	7	q13	UniSTS

BE095746

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	27,240,087 - 27,240,238 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	33,550,869 - 33,551,019	NCBI	Rnor6.0
Rnor_5.0	7	33,622,007 - 33,622,157	UniSTS	Rnor5.0
RGSC_v3.4	7	29,711,021 - 29,711,171	UniSTS	RGSC3.4
Celera	7	24,347,519 - 24,347,669	UniSTS
RH 3.4 Map	7	181.3	UniSTS
Cytogenetic Map	7	q13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		16	18	12	9	12	4	4	24	20	38		4
Low	3	27	39	29	10	29	4	7	50	15	3	11	4
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	MT415945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000005463 ⟹ ENSRNOP00000005463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	27,233,316 - 27,274,486 (-)	Ensembl
Rnor_6.0 Ensembl	7	33,543,828 - 33,584,564 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000105705 ⟹ ENSRNOP00000088691

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	27,233,316 - 27,274,486 (-)	Ensembl

RefSeq Acc Id:

NM_001106779 ⟹ NP_001100249

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	27,233,050 - 27,274,486 (-)	NCBI
Rnor_6.0	7	33,544,097 - 33,584,406 (-)	NCBI
Rnor_5.0	7	33,615,235 - 33,655,544 (-)	NCBI
RGSC_v3.4	7	29,704,249 - 29,745,416 (-)	RGD
Celera	7	24,340,948 - 24,381,914 (-)	RGD

Sequence:

show sequence

GTGGAGCCGGGCCCCCCTGTGGTCCCACGCTTGAGAGGCTCAGCCATGCAGGAAAACCTCAGAT
TTGCCTCATCAGGAGATGATGTTAAAATATGGGATGCTTCGTTTCTGACATTGGTGGATAAATT
CAACCCCCACACGTCACCGCATGGAATCAGTTCAATCTGTTGGAGCAGCAATAATAACTTCCTA
GTGACTGCGTCTTCTGGTGGTGACAAAATAGTGGTGTCAAGTTGCAAATGTAAGCCCGTTCCAC
TTTTGGAGCTTGCGGAAGGGCAAAAGCAGACATGTGTCGATTTAAATTCTACATCAATGTATTT
GGCAAGTGGAGGCCTAAATAACACTGTTAATATTTGGGATTTAAAGTCAAAACGACTTCATCGG
TCTCTTAAGGACCATAAACGGGAAGTAACTTGTGTGGCGTACAATTGGAATGATTGTTACATTG
CTTCCGGGTCTCTCAGTGGTGAGATTATCTTACACAGCGTAACCACTAATACCTCCAGTACGCC
TTTCGGCCATGGGAGTAAGCAGCCTGTCCGGCACATCAAGTACTCGTTGTTTAGGAAGTCTCTC
TTGGGCAGCGTTTCGGATAATGGAGTAGTGACCCTCTGGGATGTGAACAGTCAGAGTGCATACC
ACAGCTTTGACAGTACACACAAAGCCCCAGCTTCAGGCCTCTGCTTCTCTCCTGTCAACGAACT
GCTGTTTGTGACCATAGGCCTGGATAAAAGAATCATCCTGTATGACACTTCAAGTAAGAAGCTG
GTGAAAACTTTAGTGGCTGACACTCCTCTGACTGCTGTAGATTTTATGCCAGATGGAGCCAGTT
TGGCTATTGGATCCTCCCGTGGGAAAATATATCAGTATGACTTAAGGATGCTGAAATCTCCCGT
GAAAACCATCAGCGCCCACAAGACATCTGTGCAGTGTATAGCATTTCAGTACTCCACATCTCTG
ACGAAGGCAAGTTTAAATAAAGGCTGCTCAAATAAGGCCACAGCAGCGAACAAACGGAGTGTTC
CTGTGGGCAGCAGCAGTGGGGCTGCCCAGAATTCTGGAATTGTCAGAGAAGCACCCAGCCCTTC
CATTGCCACAGTTCTCCCACAGCCCGTGACGACAGCTGTGGGCAAAGGAGCAGGGGCTGCTCAG
GACGAAGCAGGTTTGCCTCGAAGCAAAAATACAGATATCTTATCTAAGGAAACTGATGCTGGAA
AAAGTCAAGACTTCTCCAGCTTTGATGACACGGGGAAGAGTAGTTTAGGGGACATGTTTTCACC
AATTAGAGATGATGCTGTAGTCAACAAAGGAGGTGACGAGTCTGTAGGCAAAGGAGATGGCCTT
GACTTTCTACCACAGCTAAACTCGGTGTTCCCCCTGAGGAAGAATGCAGGCTCCTCCAGCACTC
TGGTGCTGCACTCCAGCCCTTTTAATGTCCTTATGGGGACAGGGAAGGAAGAGCATGAGAGTCA
CGAGCTGTCAGCCGAGTCTAAGAAGGCACACCTTGGGAAGCCGGAGCCTAAGGACTCCTTGAAG
CAGTTTACAAAGTTGATCTCCTCTGGTGCTGAACCTGGAATTCTAAACACCTGTCCATCATCTA
ACCAAGCAAGAAATCTTGAAAAGTTTGAAAAGCCAGAAAAAGATATTGAAGTCCAGTTGATGCA
CGAACCCTCAGTCAATGGATCCTCAACTCCAGTACCAAAGGCAGCCTCCTCCGTCACTGCTGGA
GTAGCCAGTTCACTCTCAGAAAAAATAGTCGACACCCTTGGGAACAGTCGGCCGGCCGCGCCAC
TTACCTCTGTCCAGATCCGCTTCATTCAGAACATGATACAAGAAACCCTGGATGACTTCAGGGA
AGCTTGCCATAGGGACATTGTGAATCTGCAAGTGGAAATGATTAAACAGTTTCATATGCAACTG
AATGAAATGCACTCTTTGCTGGAAAGATACTCAGTGAATGAAGGCTTAGTGGCTGAGATCGAAA
GGCTGCGAGAAGAAAACAAAAGGCTGCGGGCCCACTTCTGAAGCCTCTGGACACCTTGATTTGT
TATGAGTTAGGTTTCTGGCAACTGAAATACACAGAACCAGTATTGTTCGCATGGCCTTGAAAAC
GGATTCTGCAGCGCGCACTATTCCATCTCTGTCAGACATATTATATTTTTATATTAAAACTGCA
CGGAATACCATCTTCCTAGTGGGGAAGTCAACAGGATCTTTATTTTCTGATCGCCTTAGCTATA
CACTAAGTGCCCTTTTCCTAAAAGAAAAAAAAATGTTCATATAAGAATGGGTTTATGTTTTGTA
AATGACTTTTTAAAACAGATATATTTTTGATGGACAAATTGTATTCCAAATTTTTTTAGGTAGC
CAATGTTTAAAACCCTGGTATACCTTCTATTTTATAAAGAAATAATTTTAAAGTGGCAATTGGA
TTTTTTCACAGTTTCGTAATTATTTTGTTAACATGACGACATCAGGTATGACTTATTTATTTAG
TATATATGTAATACATTTTGTGTTGTACAGATACATGGTAACTTTGTTCTGGTTACCTAACTTT
ATATAGGAAAAACTTTTAAGAGTTTGGAAGATTCAAGGGCTATGTATATCTGCTGATTGTCTAA
TGAATTAACGAAATGCAAAATCATACTCTCAGATTTTCATTACCATGACTCAACTTAGGATCAG
TGAAATTTTCTTATAAGATACTAAATATTACATATTGTTGCCATTTTTTTCCTCACAACTGAAA
GGGATAGATTATTTCTTCTGTGTTGTTTACCATTAACTTTTTCTAATTACAATGTGCTGTGAAC
AGCACTTTCTCTCTTTAGCCTTACCATAATATTATTTATAAAGATTCATCATGCAAAGAATTTA
CACGTTGGCAGCACTGACCATGTTCCTCTGCCTGCTGTGACCCACACTTTGATGGTGTTGGATG
CCTCTTGCCCAAAGATTTCATCTGTGTACTTTATACAGAGATCTGCTACCCACTTTTGCTTTCC
AGGATCAAGATGTTTACTAAAATGTAGCTTAGATTACTAACTGGGTTTCTAAAGAGGTGGAAGC
TGTTAGGGTGTATTTAATAAATATAAACTTATGAATAATTATCTCCAAAAGTGGATCAGGAGCA
GGACTTTTCCCAAGCTTCTCAGAAAGTCTATTTGTGTATCAAGTGTCCGTGGCCTTTACTTAGC
AGATATGGTGACACTATGACTTGTAACAAGTCCCCTTATATGTCACTCAAACAATGTTAGAATG
CAGAAGTCCTTTGTCTATATACTACATTTTAATCTATTAATATTTTCCTACTTCTTTTTTCTAT
AGGTGTATATATTGTGTATTAAGGGGGATCTGATAGAACATGTGTATAGGTGAACACTTGTCAT
GGATTTAAGCACTGAGGACAATAAATTTTGTATTCAAAATGT

hide sequence

RefSeq Acc Id:

XM_039078693 ⟹ XP_038934621

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	27,233,315 - 27,274,482 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100249	(Get FASTA)	NCBI Sequence Viewer
	XP_038934621	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM16930	(Get FASTA)	NCBI Sequence Viewer
	QWM97822	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001100249 ⟸ NM_001106779

- UniProtKB:

D3ZAH3 (UniProtKB/TrEMBL), A6IFW8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQENLRFASSGDDVKIWDASFLTLVDKFNPHTSPHGISSICWSSNNNFLVTASSGGDKIVVSSC
KCKPVPLLELAEGQKQTCVDLNSTSMYLASGGLNNTVNIWDLKSKRLHRSLKDHKREVTCVAYN
WNDCYIASGSLSGEIILHSVTTNTSSTPFGHGSKQPVRHIKYSLFRKSLLGSVSDNGVVTLWDV
NSQSAYHSFDSTHKAPASGLCFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDF
MPDGASLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTSLTKASLNKGCSNKATA
ANKRSVPVGSSSGAAQNSGIVREAPSPSIATVLPQPVTTAVGKGAGAAQDEAGLPRSKNTDILS
KETDAGKSQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGGDESVGKGDGLDFLPQLNSVFPLRKN
AGSSSTLVLHSSPFNVLMGTGKEEHESHELSAESKKAHLGKPEPKDSLKQFTKLISSGAEPGIL
NTCPSSNQARNLEKFEKPEKDIEVQLMHEPSVNGSSTPVPKAASSVTAGVASSLSEKIVDTLGN
SRPAAPLTSVQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEMHSLLERYSVNEG
LVAEIERLREENKRLRAHF

hide sequence

RefSeq Acc Id:

ENSRNOP00000005463 ⟸ ENSRNOT00000005463

RefSeq Acc Id:	XP_038934621 ⟸ XM_039078693
- Peptide Label:	isoform X1
- UniProtKB:	D3ZAH3 (UniProtKB/TrEMBL), A6IFW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000088691 ⟸ ENSRNOT00000105705

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZAH3-F1-model_v2	AlphaFold	D3ZAH3	1-659	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307750	AgrOrtholog
BioCyc Gene	G2FUF-34429	BioCyc
Ensembl Genes	ENSRNOG00000004011	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000005463	ENTREZGENE
	ENSRNOP00000005463.4	UniProtKB/TrEMBL
	ENSRNOP00000088691	ENTREZGENE
	ENSRNOP00000088691.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005463	ENTREZGENE
	ENSRNOT00000005463.7	UniProtKB/TrEMBL
	ENSRNOT00000105705	ENTREZGENE
	ENSRNOT00000105705.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:299730	UniProtKB/TrEMBL
NCBI Gene	299730	ENTREZGENE
PANTHER	PROTEIN NEDD1	UniProtKB/TrEMBL
	PROTEIN NEDD1	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PhenoGen	Nedd1	PhenoGen
PROSITE	WD_REPEATS_1	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	A0A8I6A9Z2_RAT	UniProtKB/TrEMBL
	A6IFW8	ENTREZGENE, UniProtKB/TrEMBL
	D3ZAH3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-08	Nedd1	NEDD1 gamma-tubulin ring complex targeting factor	Nedd1	neural precursor cell expressed, developmentally down-regulated 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Nedd1	neural precursor cell expressed, developmentally down-regulated 1	Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Nedd1	neural precursor cell expressed, developmentally down-regulated gene 1	Nedd1_predicted	neural precursor cell expressed, developmentally down-regulated gene 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Nedd1_predicted	neural precursor cell expressed, developmentally down-regulated gene 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar