Mier2 (MIER family member 2) - Rat Genome Database

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Pathways
Gene: Mier2 (MIER family member 2) Rattus norvegicus
Analyze
Symbol: Mier2
Name: MIER family member 2
RGD ID: 1307278
Description: Predicted to enable histone deacetylase binding activity and transcription corepressor activity. Predicted to contribute to histone deacetylase activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in nucleoplasm. Orthologous to human MIER2 (MIER family member 2); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362841; mesoderm induction early response 1, family member 2; mesoderm induction early response protein 2; RGD1307278; similar to KIAA1193 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,804,238 - 10,819,979 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl710,804,268 - 10,819,979 (+)EnsemblGRCr8
mRatBN7.2710,153,501 - 10,169,381 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,153,649 - 10,169,378 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx713,025,706 - 13,041,902 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,903,793 - 14,919,989 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,765,804 - 12,781,867 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,039,759 - 13,055,632 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,039,781 - 13,055,632 (+)Ensemblrn6Rnor6.0
Rnor_5.0713,203,171 - 13,219,034 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,671,223 - 11,687,698 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera78,319,518 - 8,334,990 (+)NCBICelera
RGSC_v3.1711,671,241 - 11,686,518 (+)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
nucleoplasm  (IBA,IEA)
nucleus  (IEA,ISO)
protein-containing complex  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:28046085  


Genomics

Comparative Map Data
Mier2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,804,238 - 10,819,979 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl710,804,268 - 10,819,979 (+)EnsemblGRCr8
mRatBN7.2710,153,501 - 10,169,381 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,153,649 - 10,169,378 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx713,025,706 - 13,041,902 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,903,793 - 14,919,989 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,765,804 - 12,781,867 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,039,759 - 13,055,632 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,039,781 - 13,055,632 (+)Ensemblrn6Rnor6.0
Rnor_5.0713,203,171 - 13,219,034 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4711,671,223 - 11,687,698 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera78,319,518 - 8,334,990 (+)NCBICelera
RGSC_v3.1711,671,241 - 11,686,518 (+)NCBI
Cytogenetic Map7q11NCBI
MIER2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819305,573 - 344,796 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19305,573 - 344,815 (-)Ensemblhg38GRCh38
GRCh3719305,573 - 344,796 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3619256,575 - 295,791 (-)NCBIBuild 36Build 36hg18NCBI36
Celera19467,724 - 506,032 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef1976,550 - 115,239 (-)NCBIHuRef
CHM1_119303,503 - 344,381 (-)NCBICHM1_1
T2T-CHM13v2.019255,525 - 294,230 (-)NCBIT2T-CHM13v2.0
Mier2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,376,079 - 79,395,229 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,376,079 - 79,391,033 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381079,540,245 - 79,557,042 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,540,245 - 79,555,199 (-)Ensemblmm10GRCm38
MGSCv371079,002,990 - 79,017,836 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361078,943,374 - 78,958,220 (-)NCBIMGSCv36mm8
Celera1080,553,552 - 80,568,412 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Mier2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554957,279,451 - 7,302,123 (+)Ensembl
ChiLan1.0NW_0049554957,279,507 - 7,300,202 (+)NCBIChiLan1.0ChiLan1.0
MIER2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2204,604,134 - 4,644,798 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1193,847,155 - 3,889,553 (-)NCBINHGRI_mPanPan1
PanPan1.119259,565 - 297,043 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl19259,565 - 288,920 (-)EnsemblpanPan2panpan1.1
MIER2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12058,063,976 - 58,083,041 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2058,063,449 - 58,083,083 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2057,867,332 - 57,886,361 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02058,807,791 - 58,826,821 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,807,805 - 58,826,821 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,861,617 - 57,880,644 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,341,528 - 58,360,550 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,544,998 - 58,564,027 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mier2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,788,537 - 217,809,511 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493658825,253 - 46,246 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493658825,272 - 46,226 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIER2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,912,761 - 77,938,855 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1277,912,766 - 77,938,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2279,251,675 - 79,277,764 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MIER2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,532 - 70,736 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660819,036,848 - 9,072,091 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mier2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248288,036,450 - 8,052,151 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248288,030,391 - 8,054,349 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mier2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11155,319,174 - 155,334,896 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mier2
121 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:557
Count of miRNA genes:244
Interacting mature miRNAs:316
Transcripts:ENSRNOT00000067771
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
D7Wox5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2710,156,360 - 10,156,610 (+)MAPPERmRatBN7.2
Rnor_6.0713,042,470 - 13,042,719NCBIRnor6.0
Rnor_5.0713,206,016 - 13,206,265UniSTSRnor5.0
RGSC_v3.4711,673,911 - 11,674,161RGDRGSC3.4
RGSC_v3.4711,673,912 - 11,674,161UniSTSRGSC3.4
Celera78,322,207 - 8,322,456UniSTS
RGSC_v3.1711,673,911 - 11,674,161RGD
Cytogenetic Map7q11UniSTS
AW610739  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2710,169,208 - 10,169,354 (+)MAPPERmRatBN7.2
Rnor_6.0713,055,460 - 13,055,605NCBIRnor6.0
Rnor_5.0713,218,862 - 13,219,007UniSTSRnor5.0
RGSC_v3.4711,687,528 - 11,687,673UniSTSRGSC3.4
Celera78,334,820 - 8,334,965UniSTS
Cytogenetic Map7q11UniSTS
RH133107  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2710,162,150 - 10,162,358 (+)MAPPERmRatBN7.2
Rnor_6.0713,048,403 - 13,048,610NCBIRnor6.0
Rnor_5.0713,211,805 - 13,212,012UniSTSRnor5.0
RGSC_v3.4711,680,471 - 11,680,678UniSTSRGSC3.4
Celera78,328,015 - 8,328,222UniSTS
Cytogenetic Map7q11UniSTS
UniSTS:236396  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2710,168,935 - 10,169,143 (+)MAPPERmRatBN7.2
Rnor_6.0713,055,187 - 13,055,394NCBIRnor6.0
Rnor_5.0713,218,589 - 13,218,796UniSTSRnor5.0
RGSC_v3.4711,687,255 - 11,687,462UniSTSRGSC3.4
Celera78,334,547 - 8,334,754UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001394321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010053001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000067771   ⟹   ENSRNOP00000060254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,804,268 - 10,819,798 (+)Ensembl
mRatBN7.2 Ensembl710,153,687 - 10,169,378 (+)Ensembl
Rnor_6.0 Ensembl713,039,781 - 13,055,630 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090048   ⟹   ENSRNOP00000068538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,809,211 - 10,819,979 (+)Ensembl
mRatBN7.2 Ensembl710,153,649 - 10,169,374 (+)Ensembl
Rnor_6.0 Ensembl713,039,904 - 13,055,632 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103560   ⟹   ENSRNOP00000084610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl710,809,211 - 10,819,798 (+)Ensembl
RefSeq Acc Id: NM_001394321   ⟹   NP_001381250
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,270 - 10,819,979 (+)NCBI
mRatBN7.2710,153,670 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_017594912   ⟹   XP_017450401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,313 - 10,819,976 (+)NCBI
mRatBN7.2710,153,710 - 10,169,381 (+)NCBI
Rnor_6.0713,039,817 - 13,055,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594913   ⟹   XP_017450402
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,238 - 10,819,976 (+)NCBI
mRatBN7.2710,153,580 - 10,169,381 (+)NCBI
Rnor_6.0713,039,759 - 13,055,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594914   ⟹   XP_017450403
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,491 - 10,819,976 (+)NCBI
mRatBN7.2710,153,892 - 10,169,381 (+)NCBI
Rnor_6.0713,040,012 - 13,055,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594915   ⟹   XP_017450404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,491 - 10,819,976 (+)NCBI
mRatBN7.2710,153,894 - 10,169,381 (+)NCBI
Rnor_6.0713,040,014 - 13,055,632 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079407   ⟹   XP_038935335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,819,976 (+)NCBI
mRatBN7.2710,153,501 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_039079408   ⟹   XP_038935336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,819,976 (+)NCBI
mRatBN7.2710,153,501 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_039079409   ⟹   XP_038935337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,491 - 10,819,976 (+)NCBI
mRatBN7.2710,153,892 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_039079410   ⟹   XP_038935338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,491 - 10,819,976 (+)NCBI
mRatBN7.2710,153,892 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_039079411   ⟹   XP_038935339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,491 - 10,819,976 (+)NCBI
mRatBN7.2710,153,892 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_039079412   ⟹   XP_038935340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,809,576 - 10,819,976 (+)NCBI
mRatBN7.2710,158,960 - 10,169,381 (+)NCBI
RefSeq Acc Id: XM_063263747   ⟹   XP_063119817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,818,497 (+)NCBI
RefSeq Acc Id: XM_063263748   ⟹   XP_063119818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,491 - 10,819,976 (+)NCBI
RefSeq Acc Id: XM_063263749   ⟹   XP_063119819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,441 - 10,819,976 (+)NCBI
RefSeq Acc Id: XR_010052993
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010052994
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010052995
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010052996
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010052997
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010052998
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010052999
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010053000
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XR_010053001
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8710,804,254 - 10,817,652 (+)NCBI
RefSeq Acc Id: XP_017450402   ⟸   XM_017594913
- Peptide Label: isoform X4
- UniProtKB: A6K903 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450401   ⟸   XM_017594912
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017450403   ⟸   XM_017594914
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450404   ⟸   XM_017594915
- Peptide Label: isoform X2
- UniProtKB: D3ZR39 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000060254   ⟸   ENSRNOT00000067771
Ensembl Acc Id: ENSRNOP00000068538   ⟸   ENSRNOT00000090048
RefSeq Acc Id: XP_038935335   ⟸   XM_039079407
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935336   ⟸   XM_039079408
- Peptide Label: isoform X2
- UniProtKB: D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935339   ⟸   XM_039079411
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935337   ⟸   XM_039079409
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935338   ⟸   XM_039079410
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935340   ⟸   XM_039079412
- Peptide Label: isoform X6
- UniProtKB: A6K907 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001381250   ⟸   NM_001394321
- UniProtKB: A6K904 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119817   ⟸   XM_063263747
- Peptide Label: isoform X5
- UniProtKB: A6K906 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119819   ⟸   XM_063263749
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119818   ⟸   XM_063263748
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JT20 (UniProtKB/TrEMBL),   D3ZR39 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084610   ⟸   ENSRNOT00000103560
Protein Domains
ELM2   SANT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JT20-F1-model_v2 AlphaFold A0A0G2JT20 1-509 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695060
Promoter ID:EPDNEW_R5584
Type:multiple initiation site
Name:Mier2_1
Description:MIER family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0713,039,786 - 13,039,846EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307278 AgrOrtholog
BioCyc Gene G2FUF-34873 BioCyc
Ensembl Genes ENSRNOG00000000175 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067771.4 UniProtKB/TrEMBL
  ENSRNOT00000090048 ENTREZGENE
  ENSRNOT00000090048.3 UniProtKB/TrEMBL
  ENSRNOT00000103560.2 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro ELM2_dom UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  MIER/MTA UniProtKB/TrEMBL
  SANT_DNA-bd UniProtKB/TrEMBL
  SANT_eukarya UniProtKB/TrEMBL
NCBI Gene 362841 ENTREZGENE
PANTHER MESODERM INDUCTION EARLY RESPONSE PROTEIN 2 UniProtKB/TrEMBL
  PTHR10865 UniProtKB/TrEMBL
Pfam ELM2 UniProtKB/TrEMBL
  Myb_DNA-binding UniProtKB/TrEMBL
PhenoGen Mier2 PhenoGen
PROSITE ELM2 UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000175 RatGTEx
SMART ELM2 UniProtKB/TrEMBL
  SANT UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A0G2JT20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GAR1_RAT UniProtKB/TrEMBL
  A6K903 ENTREZGENE, UniProtKB/TrEMBL
  A6K904 ENTREZGENE, UniProtKB/TrEMBL
  A6K906 ENTREZGENE, UniProtKB/TrEMBL
  A6K907 ENTREZGENE, UniProtKB/TrEMBL
  D3ZR39 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-02-15 Mier2  MIER family member 2  Mier2  mesoderm induction early response 1, family member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Mier2  mesoderm induction early response 1, family member 2  RGD1307278_predicted  similar to KIAA1193 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1307278_predicted  similar to KIAA1193 protein (predicted)  LOC362841_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362841_predicted  similar to KIAA1193 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL