Scyl2 (SCY1 like pseudokinase 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Scyl2 (SCY1 like pseudokinase 2) Rattus norvegicus
Analyze
Symbol: Scyl2
Name: SCY1 like pseudokinase 2
RGD ID: 1305665
Description: Predicted to enable signaling receptor binding activity. Predicted to be involved in several processes, including positive regulation of receptor-mediated endocytosis; pyramidal neuron development; and receptor internalization involved in canonical Wnt signaling pathway. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-4. Orthologous to human SCYL2 (SCY1 like pseudokinase 2); INTERACTS WITH bisphenol A; gentamycin; 1,2-dimethylhydrazine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical LOC314717; LOC314717; RGD1305665; SCY1-like 2; SCY1-like 2 (S. cerevisiae); SCY1-like protein 2; SCY1-like, kinase-like 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2724,064,404 - 24,117,338 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)Ensembl
Rnor_6.0730,291,087 - 30,344,464 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,291,087 - 30,344,445 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,387,991 - 30,441,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,429,923 - 26,483,533 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1726,451,520 - 26,503,820 (-)NCBI
Celera721,207,836 - 21,260,716 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19643732   PMID:25931508  


Genomics

Comparative Map Data
Scyl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2724,064,404 - 24,117,338 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)Ensembl
Rnor_6.0730,291,087 - 30,344,464 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,291,087 - 30,344,445 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,387,991 - 30,441,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,429,923 - 26,483,533 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1726,451,520 - 26,503,820 (-)NCBI
Celera721,207,836 - 21,260,716 (-)NCBICelera
Cytogenetic Map7q13NCBI
SCYL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812100,267,177 - 100,341,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12100,267,140 - 100,341,715 (+)EnsemblGRCh38hg38GRCh38
GRCh3712100,660,955 - 100,735,493 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,185,680 - 99,258,048 (+)NCBINCBI36hg18NCBI36
Build 341299,164,016 - 99,236,380NCBI
Celera12100,326,815 - 100,399,182 (+)NCBI
Cytogenetic Map12q23.1NCBI
HuRef1297,722,877 - 97,795,047 (+)NCBIHuRef
CHM1_112100,627,192 - 100,699,929 (+)NCBICHM1_1
T2T-CHM13v2.012100,228,403 - 100,303,144 (+)NCBI
Scyl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,474,582 - 89,522,179 (-)NCBIGRCm39mm39
GRCm39 Ensembl1089,474,583 - 89,522,147 (-)Ensembl
GRCm381089,638,720 - 89,686,317 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,638,721 - 89,686,285 (-)EnsemblGRCm38mm10GRCm38
MGSCv371089,102,852 - 89,149,030 (-)NCBIGRCm37mm9NCBIm37
MGSCv361089,069,906 - 89,116,084 (-)NCBImm8
Celera1091,640,299 - 91,687,002 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1045.05NCBI
Scyl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540535,984,667 - 36,043,628 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540535,984,667 - 36,043,581 (+)NCBIChiLan1.0ChiLan1.0
SCYL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112101,255,169 - 101,326,808 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12101,255,412 - 101,326,808 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01297,848,852 - 97,920,561 (+)NCBIMhudiblu_PPA_v0panPan3
SCYL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11539,365,702 - 39,429,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1539,365,157 - 39,428,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1539,744,679 - 39,808,502 (+)NCBI
ROS_Cfam_1.01540,028,775 - 40,093,229 (+)NCBI
ROS_Cfam_1.0 Ensembl1540,028,228 - 40,093,033 (+)Ensembl
UMICH_Zoey_3.11539,286,373 - 39,350,816 (+)NCBI
UNSW_CanFamBas_1.01539,392,749 - 39,457,180 (+)NCBI
UU_Cfam_GSD_1.01539,666,912 - 39,731,343 (+)NCBI
Scyl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,492,420 - 20,554,460 (-)NCBI
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCYL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl583,812,681 - 83,878,751 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1583,813,207 - 83,878,766 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2588,004,752 - 88,052,916 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCYL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11195,582,856 - 95,655,974 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037149,389,158 - 149,462,368 (-)NCBIVero_WHO_p1.0
Scyl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247507,412,869 - 7,477,965 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AW529585  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,064,531 - 24,064,716 (+)MAPPERmRatBN7.2
Rnor_6.0730,291,215 - 30,291,399NCBIRnor6.0
Rnor_5.0730,388,119 - 30,388,303UniSTSRnor5.0
RGSC_v3.4726,430,051 - 26,430,235UniSTSRGSC3.4
Celera721,207,964 - 21,208,148UniSTS
RH 3.4 Map7128.9UniSTS
Cytogenetic Map7q13UniSTS
RH135279  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,065,719 - 24,065,935 (+)MAPPERmRatBN7.2
Rnor_6.0730,292,403 - 30,292,618NCBIRnor6.0
Rnor_5.0730,389,307 - 30,389,522UniSTSRnor5.0
RGSC_v3.4726,431,239 - 26,431,454UniSTSRGSC3.4
Celera721,209,152 - 21,209,367UniSTS
RH 3.4 Map7122.4UniSTS
Cytogenetic Map7q13UniSTS
RH138216  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2724,085,164 - 24,085,309 (+)MAPPERmRatBN7.2
Rnor_6.0730,311,942 - 30,312,086NCBIRnor6.0
Rnor_5.0730,408,846 - 30,408,990UniSTSRnor5.0
RGSC_v3.4726,451,394 - 26,451,538UniSTSRGSC3.4
Celera721,228,574 - 21,228,718UniSTS
RH 3.4 Map7127.1UniSTS
Cytogenetic Map7q13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:743
Count of miRNA genes:294
Interacting mature miRNAs:366
Transcripts:ENSRNOT00000002638
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 55 39 19 39 2 2 74 35 41 11 2
Low 14 2 2 2 6 9 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002638   ⟹   ENSRNOP00000002638
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)Ensembl
Rnor_6.0 Ensembl730,291,087 - 30,344,426 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082016   ⟹   ENSRNOP00000069426
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)Ensembl
Rnor_6.0 Ensembl730,291,435 - 30,344,445 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119175   ⟹   ENSRNOP00000091677
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl724,064,754 - 24,117,304 (-)Ensembl
RefSeq Acc Id: NM_001191780   ⟹   NP_001178709
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2724,064,404 - 24,117,305 (-)NCBI
Rnor_6.0730,291,087 - 30,344,426 (-)NCBI
Rnor_5.0730,387,991 - 30,441,350 (-)NCBI
Celera721,207,836 - 21,260,716 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241241   ⟹   XP_006241303
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2724,064,415 - 24,117,338 (-)NCBI
Rnor_6.0730,291,087 - 30,344,464 (-)NCBI
Rnor_5.0730,387,991 - 30,441,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006241242   ⟹   XP_006241304
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2724,064,415 - 24,117,338 (-)NCBI
Rnor_6.0730,291,087 - 30,344,464 (-)NCBI
Rnor_5.0730,387,991 - 30,441,350 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594827   ⟹   XP_017450316
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2724,064,415 - 24,117,338 (-)NCBI
Rnor_6.0730,291,087 - 30,344,464 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001178709   ⟸   NM_001191780
- UniProtKB: D4A1Y0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241304   ⟸   XM_006241242
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006241303   ⟸   XM_006241241
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450316   ⟸   XM_017594827
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000069426   ⟸   ENSRNOT00000082016
RefSeq Acc Id: ENSRNOP00000002638   ⟸   ENSRNOT00000002638
RefSeq Acc Id: ENSRNOP00000091677   ⟸   ENSRNOT00000119175
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVC2-F1-model_v2 AlphaFold A0A0G2JVC2 1-934 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695136
Promoter ID:EPDNEW_R5661
Type:initiation region
Name:Scyl2_1
Description:SCY1 like pseudokinase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0730,344,425 - 30,344,485EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305665 AgrOrtholog
BioCyc Gene G2FUF-34487 BioCyc
Ensembl Genes ENSRNOG00000024955 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002638 ENTREZGENE
  ENSRNOP00000002638.5 UniProtKB/TrEMBL
  ENSRNOP00000069426 ENTREZGENE
  ENSRNOP00000069426.1 UniProtKB/TrEMBL
  ENSRNOP00000091677 ENTREZGENE
  ENSRNOP00000091677.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002638 ENTREZGENE
  ENSRNOT00000002638.8 UniProtKB/TrEMBL
  ENSRNOT00000082016 ENTREZGENE
  ENSRNOT00000082016.2 UniProtKB/TrEMBL
  ENSRNOT00000119175 ENTREZGENE
  ENSRNOT00000119175.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
KEGG Report rno:314717 UniProtKB/TrEMBL
NCBI Gene 314717 ENTREZGENE
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Scyl2 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
  Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2JVC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFM7_RAT UniProtKB/TrEMBL
  D4A1Y0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Scyl2  SCY1 like pseudokinase 2  Scyl2  SCY1-like, kinase-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-30 Scyl2  SCY1-like, kinase-like 2  Scyl2  SCY1-like 2 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Scyl2  SCY1-like 2 (S. cerevisiae)   Scyl2_predicted  SCY1-like 2 (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Scyl2_predicted  SCY1-like 2 (S. cerevisiae) (predicted)  RGD1305665_predicted  hypothetical LOC314717 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305665_predicted  hypothetical LOC314717 (predicted)  LOC314717_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314717_predicted  hypothetical LOC314717 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL