Or7a41 (olfactory receptor family 7 subfamily A member 41) - Rat Genome Database

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Gene: Or7a41 (olfactory receptor family 7 subfamily A member 41) Rattus norvegicus
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Symbol: Or7a41
Name: olfactory receptor family 7 subfamily A member 41
RGD ID: 1333658
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Orthologous to several human genes including OR7A17 (olfactory receptor family 7 subfamily A member 17) and OR7A2P (olfactory receptor family 7 subfamily A member 2 pseudogene); INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1075; olfactory receptor gene Olr1075; olfactory receptor Olr1075; Olr1075
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,166,163 - 11,167,122 (-)NCBIGRCr8
mRatBN7.2710,515,567 - 10,516,526 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,515,567 - 10,516,526 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,381,852 - 13,382,811 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,259,296 - 15,260,255 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,102,501 - 13,103,460 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,403,899 - 13,404,858 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,403,899 - 13,404,858 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,607,716 - 13,608,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,042,578 - 12,043,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,042,577 - 12,043,537 (-)NCBI
Celera78,659,725 - 8,660,684 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or7a41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,166,163 - 11,167,122 (-)NCBIGRCr8
mRatBN7.2710,515,567 - 10,516,526 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,515,567 - 10,516,526 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,381,852 - 13,382,811 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,259,296 - 15,260,255 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,102,501 - 13,103,460 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,403,899 - 13,404,858 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,403,899 - 13,404,858 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,607,716 - 13,608,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,042,578 - 12,043,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,042,577 - 12,043,537 (-)NCBI
Celera78,659,725 - 8,660,684 (-)NCBICelera
Cytogenetic Map7q11NCBI
OR7A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,826,241 - 14,835,185 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,826,241 - 14,835,185 (-)EnsemblGRCh38hg38GRCh38
GRCh371914,937,053 - 14,945,997 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,798,139 - 14,800,276 (-)NCBINCBI36Build 36hg18NCBI36
Build 341914,798,138 - 14,800,276NCBI
Celera1914,832,918 - 14,835,055 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,505,005 - 14,507,142 (-)NCBIHuRef
CHM1_11914,936,616 - 14,938,753 (-)NCBICHM1_1
T2T-CHM13v2.01914,953,804 - 14,962,748 (-)NCBIT2T-CHM13v2.0
Or7a41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,870,557 - 78,871,636 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,864,575 - 78,872,108 (+)EnsemblGRCm39 Ensembl
GRCm381079,034,723 - 79,035,802 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,028,741 - 79,036,274 (+)EnsemblGRCm38mm10GRCm38
MGSCv371078,497,468 - 78,498,547 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,437,927 - 78,438,886 (+)NCBIMGSCv36mm8
Celera1080,054,143 - 80,055,222 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
LOC100978244
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,742,313 - 19,750,610 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,759,299 - 18,767,596 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,375,924 - 14,384,213 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,348,472 - 15,355,409 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,348,472 - 15,349,431 (-)Ensemblpanpan1.1panPan2
OR7A26
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,178,016 - 47,179,006 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,178,077 - 47,179,370 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2047,034,710 - 47,035,699 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,675,926 - 47,676,915 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,675,986 - 47,676,915 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,900,218 - 46,901,207 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02047,318,460 - 47,319,449 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,590,640 - 47,591,629 (+)NCBIUU_Cfam_GSD_1.0
LOC100525562
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1263,348,429 - 63,349,361 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2263,299,555 - 63,300,487 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Or7a41
6 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:173
Count of miRNA genes:127
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000060456
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
6 3 1 6 4 3 2 6

Sequence


Ensembl Acc Id: ENSRNOT00000060456   ⟹   ENSRNOP00000057201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,515,567 - 10,516,526 (-)Ensembl
Rnor_6.0 Ensembl713,403,899 - 13,404,858 (-)Ensembl
RefSeq Acc Id: NM_001000421   ⟹   NP_001000421
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,166,163 - 11,167,122 (-)NCBI
mRatBN7.2710,515,567 - 10,516,526 (-)NCBI
Rnor_6.0713,403,899 - 13,404,858 (-)NCBI
Rnor_5.0713,607,716 - 13,608,675 (-)NCBI
RGSC_v3.4712,042,578 - 12,043,537 (-)RGD
Celera78,659,725 - 8,660,684 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000421 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL89437 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000057200.4
  ENSRNOP00000057201.1
RefSeq Acc Id: NP_001000421   ⟸   NM_001000421
- UniProtKB: D4AD59 (UniProtKB/TrEMBL),   A6K917 (UniProtKB/TrEMBL),   D4AD60 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057201   ⟸   ENSRNOT00000060456
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AD59-F1-model_v2 AlphaFold D4AD59 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333658 AgrOrtholog
BioCyc Gene G2FUF-34861 BioCyc
Ensembl Genes ENSRNOG00000039448 UniProtKB/TrEMBL
  ENSRNOG00000039449 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060455.4 UniProtKB/TrEMBL
  ENSRNOT00000060456.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:299596 UniProtKB/TrEMBL
NCBI Gene 299596 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 1351 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7a41 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039448 RatGTEx
  ENSRNOG00000039449 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6K917 ENTREZGENE, UniProtKB/TrEMBL
  D4AD59 ENTREZGENE, UniProtKB/TrEMBL
  D4AD60 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7a41  olfactory receptor family 7 subfamily A member 41  Olr1075  olfactory receptor 1075  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1075  olfactory receptor 1075   Olr1075_predicted  olfactory receptor 1075 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1075_predicted  olfactory receptor 1075 (predicted)      Symbol and Name status set to approved 70820 APPROVED