Gene: Lta4h (leukotriene A4 hydrolase) Rattus norvegicus
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Symbol: Lta4h
Name: leukotriene A4 hydrolase
Description: Exhibits leukotriene-A4 hydrolase activity. Involved in several processes, including leukotriene metabolic process; response to zinc ion; and type I pneumocyte differentiation. Localizes to the cytoplasm and nucleus. Biomarker of adenocarcinoma; asthma; and squamous cell carcinoma. Orthologous to human LTA4H (leukotriene A4 hydrolase); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leukotriene A-4 hydrolase; LOC299732; LTA-4 hydrolase
Orthologs:
Homo sapiens (human) : LTA4H (leukotriene A4 hydrolase)  HGNC  Alliance
Mus musculus (house mouse) : Lta4h (leukotriene A4 hydrolase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lta4h (leukotriene A4 hydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : LTA4H (leukotriene A4 hydrolase)
Canis lupus familiaris (dog) : LTA4H (leukotriene A4 hydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lta4h (leukotriene A4 hydrolase)
Sus scrofa (pig) : LTA4H (leukotriene A4 hydrolase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0734,288,333 - 34,320,243 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0734,353,476 - 34,385,291 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4730,482,213 - 30,515,062 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1730,502,483 - 30,535,333 (+)NCBI
Celera725,071,700 - 25,102,147 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Lta4h
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311333
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.