Nup37 (nucleoporin 37) - Rat Genome Database

Name: Nup37
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Nup37 (nucleoporin 37) Rattus norvegicus

Analyze

Symbol:

Nup37

Name:

nucleoporin 37

RGD ID:

1307774

Description:

Predicted to have porin activity. Predicted to be involved in transmembrane transport. Predicted to colocalize with kinetochore. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NUP37 (nucleoporin 37); PARTICIPATES IN mRNA nuclear export pathway; RNA transport pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,6-dinitrotoluene; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC299706; nucleoporin Nup37

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NUP37 (nucleoporin 37)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nup37 (nucleoporin 37)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Nup37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NUP37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NUP37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nup37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NUP37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	NUP37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nup37 (nucleoporin 37)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	NUP37 (nucleoporin 37)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Nup37 (nucleoporin 37)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	Nup37	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	22,556,544 - 22,609,622 (+)	NCBI
Rnor_6.0 Ensembl	7	28,701,690 - 28,743,326 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	7	28,715,299 - 28,750,978 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	28,825,280 - 28,860,960 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	24,847,159 - 24,875,363 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	24,869,532 - 24,895,483 (+)	NCBI
Celera	7	19,736,956 - 19,765,160 (+)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Primary Autosomal Recessive Microcephaly 24 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

calcitriol (ISO)

captan (ISO)

carbon nanotube (ISO)

casticin (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dicrotophos (ISO)

finasteride (EXP)

flutamide (EXP)

folpet (ISO)

indometacin (ISO)

methapyrilene (EXP)

oxaliplatin (EXP)

paracetamol (ISO)

PCB138 (ISO)

pirinixic acid (EXP)

potassium chromate (ISO)

rac-lactic acid (ISO)

rotenone (EXP)

Salinomycin (ISO)

sodium dichromate (ISO)

sodium fluoride (ISO)

Soman (EXP)

sulindac (EXP)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

topotecan (EXP)

trimellitic anhydride (ISO)

tungsten (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

transmembrane transport (IEA)

Cellular Component

cellular_component (ND)

kinetochore (ISO)

nuclear pore outer ring (IBA,ISO)

nucleoplasm (IEA,ISO)

pore complex (IEA)

Molecular Function

molecular_function (ND)

porin activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mRNA nuclear export pathway (ISO)

RNA transport pathway (IEA)

References

References - curated


1.	Bonnet A and Palancade B, Genes (Basel). 2014 Sep 2;5(3):767-91. doi: 10.3390/genes5030767.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Pipeline to import KEGG annotations from KEGG into RGD
4.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	RGD automated import pipeline for gene-chemical interactions
6.	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:15146057	PMID:17360435	PMID:21630459

Genomics

Comparative Map Data

Nup37
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	7	22,556,544 - 22,609,622 (+)	NCBI
Rnor_6.0 Ensembl	7	28,701,690 - 28,743,326 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	7	28,715,299 - 28,750,978 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	7	28,825,280 - 28,860,960 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	24,847,159 - 24,875,363 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	7	24,869,532 - 24,895,483 (+)	NCBI
Celera	7	19,736,956 - 19,765,160 (+)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

NUP37
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	12	102,073,103 - 102,120,120 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	12	102,073,103 - 102,120,131 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	12	102,466,881 - 102,513,892 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	100,992,100 - 101,036,491 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	12	100,970,441 - 101,014,828	NCBI
Celera	12	102,131,991 - 102,176,381 (-)	NCBI
Cytogenetic Map	12	q23.2	NCBI
HuRef	12	99,527,621 - 99,571,949 (-)	NCBI		HuRef
CHM1_1	12	102,434,634 - 102,480,575 (-)	NCBI		CHM1_1

Nup37
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	87,982,838 - 88,014,257 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	10	87,982,854 - 88,014,252 (+)	Ensembl
GRCm38	10	88,146,976 - 88,178,395 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	88,146,992 - 88,178,390 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	87,609,737 - 87,641,140 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	10	87,576,847 - 87,608,193 (+)	NCBI			mm8
Celera	10	90,124,078 - 90,155,478 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI

Nup37
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	37,258,294 - 37,297,762 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955405	37,215,324 - 37,297,762 (-)	NCBI	ChiLan1.0	ChiLan1.0

NUP37
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	12	103,059,232 - 103,105,066 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	103,059,232 - 103,105,066 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	12	99,661,779 - 99,707,618 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

NUP37
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	15	40,930,281 - 40,972,239 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	15	40,930,321 - 40,972,092 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Nup37
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936492	11,998,967 - 12,036,357 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NUP37
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	82,091,517 - 82,145,556 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	82,091,439 - 82,144,463 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	86,067,263 - 86,118,880 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NUP37
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	97,319,980 - 97,367,237 (-)	NCBI
ChlSab1.1 Ensembl	11	97,319,853 - 97,367,207 (-)	Ensembl

Nup37
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624750	6,163,379 - 6,202,782 (+)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	34147172	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	34828535	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	34828535	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	37009673	Rat
2317047	Wbc4	White blood cell count QTL 4		0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	7	1	38119654	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	2653138	32258115	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	2920071	124838025	Rat
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	5911477	50911477	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	5951969	50951969	Rat
10755438	Coatc9	Coat color QTL 9		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	9758045	54758045	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	11647102	56647102	Rat
2298547	Neuinf5	Neuroinflammation QTL 5	3.7		nervous system integrity trait (VT:0010566)	spinal cord Cd74 protein level (CMO:0002131)	7	12328467	67193263	Rat
1643004	Pain2	Pain QTL 2	1		mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	7	12328467	106995532	Rat
1578652	Bmd15	Bone mineral density QTL 15	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	7	12687850	67801690	Rat
10755440	Coatc10	Coat color QTL 10		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	13952179	58952179	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	14445685	59445685	Rat
1582260	Bw72	Body weight QTL 72	3.2	0.0043	body mass (VT:0001259)	body weight (CMO:0000012)	7	20215583	44668493	Rat
1582261	Bw69	Body weight QTL 69	3.2	0.0048	body mass (VT:0001259)	body weight (CMO:0000012)	7	20215583	44668493	Rat
1582262	Bw75	Body weight QTL 75	3	0.0038	body mass (VT:0001259)	body weight (CMO:0000012)	7	20215583	44668493	Rat
738033	Anxrr6	Anxiety related response QTL 6	4.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	7	22168412	67168412	Rat
70207	Niddm31	Non-insulin dependent diabetes mellitus QTL 31	3.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	24175337	32258115	Rat
10755451	Coatc11	Coat color QTL 11		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	24731465	69731465	Rat
61369	Mcs2	Mammary carcinoma susceptibility QTL 2	3.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	7	24738680	40433335	Rat
1354644	Spl4	Serum phospholipid level QTL 4	4.9		blood phospholipid amount (VT:0006084)	blood phospholipid level (CMO:0001169)	7	25365633	57064364	Rat
1354637	Scl30	Serum cholesterol level QTL 30	3.7		blood cholesterol amount (VT:0000180)	blood total cholesterol level (CMO:0000051)	7	25365633	57064364	Rat
1354639	Spl5	Serum phospholipid level QTL 5	3.9		blood LDL phospholipid amount (VT:0010505)	blood low density lipoprotein phospholipid level (CMO:0001568)	7	25365633	60317612	Rat
1300132	Bp182	Blood pressure QTL 182	3.49		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	7	25365633	93155402	Rat
2290372	Gluco33	Glucose level QTL 33	2.71		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	26508887	36346595	Rat
7411569	Bw137	Body weight QTL 137		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	28204653	73204653	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	121
Count of miRNA genes:	86
Interacting mature miRNAs:	93
Transcripts:	ENSRNOT00000006760
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	20	24	18	13	18			34	20	38	6
Low	1	23	33	23	6	23	8	11	40	15	3	5	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106775	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241198	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005486570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091253	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC161937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000006760 ⟹ ENSRNOP00000006760

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	28,715,300 - 28,743,326 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000079168 ⟹ ENSRNOP00000072699

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	28,701,690 - 28,743,279 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089161 ⟹ ENSRNOP00000075343

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	7	28,715,331 - 28,743,325 (+)	Ensembl

RefSeq Acc Id:

NM_001106775 ⟹ NP_001100245

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,573,764 - 22,601,970 (+)	NCBI
Rnor_6.0	7	28,715,300 - 28,743,326 (+)	NCBI
Rnor_5.0	7	28,825,280 - 28,860,960 (+)	NCBI
RGSC_v3.4	7	24,847,159 - 24,875,363 (+)	RGD
Celera	7	19,736,956 - 19,765,160 (+)	RGD

Sequence:

show sequence

GACCCGGAAGCAGAGCGGGCGCTCGCCGCGGCCGCCCTTGGTCATGAGAGTGGTACCCAGGTCG
CCTCCCCTGCATTAGGTGCGTATGGAGCGCGGTGGCCCGGGATCGCCAGCTTGTGCTACTTCCC
CAGGGGCCCTTCCATGTTCCCCAGAGCTCTTCCCTGTGACCTCGCGAGTTTTGTGACAGCCAAT
AAAAGAACATTTTGATCCTCACCACTGCTCAAGCTTTGGAATACAAGATGAAGCAAGACGTTAC
AAGAAACGCTGCCTATACGGTGGATTGTGAAGATTATGTGCATGTGGTAGAATTTAATCCCTTT
GAGAGTGGAGAGTCGGGAAACCTGATCGCATATGGCGGCAGTAATTATGTGGTTGTTGGCATGT
GTATGTTTCAGGAGGAAGGAACAGACACTGAAGGAATTCAGTACAAAACACTACGAACATTTCA
CCATGGAGTCCGAGTTGATGGCATTGCCTGGAGCCCAGAGACCAAGCTTGATTCGCTGCCTCCC
GTAATCAAATTTTGTACGTCAGCCGCTGATATGAAGATTAGATTATTTACTTCAGACCTTCAAG
ATAAAAATGAATATAAGGTTTTGGAGGGCCACTCGGATTTCATTAATGATTTGGTGTTTCATCC
CAGAGAAGGCCAGGAAATCGCGAGTGTGAGTGACGACCATACCTGCAGGATTTGGAGCTTGGAA
GGAAAGCAGACAGCTCATTTTCTTCTTCATTCTCCTGGAATGAGTGTATGCTGGCATCCTGAGG
AAACTTTCAAGCTAATGGTCGCAGAGAAGAACGGAACAATCCGGTTTTATGATCTAATGGCCCA
GCAGGCAATTTTATCTCTTCAGTCAGAACAGACACCATTAATGTCAGCACACTGGTGCTTGAAA
AACACCTTCAAAGTTGGTGCTGTTGCAGGAAATGATTGGATTATCTGGGATATCACTCGGTCCA
GTTATCCTCAAGAGACAAGACCTGTCCACATGGATCGCGCACACTCGTTTAGGTGGTCTGCCAT
TAGTGAAAACCTGTTTGCAACCACTGGATATCCTGGCAAAATGTCCAGTCAGTTTCAGATTCAT
CATTTAGGACACTCTCAGCCCATCCTCATTGGCTCTGTACCTGTCGGATCTGGTCTTTCCTGGC
ACAGAACACTCCCGCTGTGTGCAGTTGGAGGAGACCATAAGCTCTTGTTCTGGGTGACAGAAAT
ATGATTTCCCTCTGTATTTTTAATCCTACACTTTGTATTTTTAGTATATATTTTGGAAAAAATA
CTTATTTTTATATCAAACATACTGTAAGTCTAGAAATGCCTCAGTTGTCTTTTCTGATAAATAA
AATGATAAAGACTTCTTGAAAATTA

hide sequence

RefSeq Acc Id:

XM_006241197 ⟹ XP_006241259

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,573,704 - 22,601,970 (+)	NCBI
Rnor_6.0	7	28,715,299 - 28,743,326 (+)	NCBI
Rnor_5.0	7	28,825,280 - 28,860,960 (+)	NCBI

Sequence:

show sequence

CGACCCGGAAGCAGAGCGGGCGCTCGCCGCGGCCGCCCTTGGTCATGAGAGTGGTACCCAGGTC
GCCTCCCCTGCATTAGTTTTGTGACAGCCAATAAAAGAACATTTTGATCCTCACCACTGCTCAA
GCTTTGGAATACAAGATGAAGCAAGACGTTACAAGAAACGCTGCCTATACGGTGGATTGTGAAG
ATTATGTGCATGTGGTAGAATTTAATCCCTTTGAGAGTGGAGAGTCGGGAAACCTGATCGCATA
TGGCGGCAGTAATTATGTGGTTGTTGGCATGTGTATGTTTCAGGAGGAAGGAACAGACACTGAA
GGAATTCAGTACAAAACACTACGAACATTTCACCATGGAGTCCGAGTTGATGGCATTGCCTGGA
GCCCAGAGACCAAGCTTGATTCGCTGCCTCCCGTAATCAAATTTTGTACGTCAGCCGCTGATAT
GAAGATTAGATTATTTACTTCAGACCTTCAAGATAAAAATGAATATAAGGTTTTGGAGGGCCAC
TCGGATTTCATTAATGATTTGGTGTTTCATCCCAGAGAAGGCCAGGAAATCGCGAGTGTGAGTG
ACGACCATACCTGCAGGATTTGGAGCTTGGAAGGAAAGCAGACAGCTCATTTTCTTCTTCATTC
TCCTGGAATGAGTGTATGCTGGCATCCTGAGGAAACTTTCAAGCTAATGGTCGCAGAGAAGAAC
GGAACAATCCGGTTTTATGATCTAATGGCCCAGCAGGCAATTTTATCTCTTCAGTCAGAACAGA
CACCATTAATGTCAGCACACTGGTGCTTGAAAAACACCTTCAAAGTTGGTGCTGTTGCAGGAAA
TGATTGGATTATCTGGGATATCACTCGGTCCAGTTATCCTCAAGAGACAAGACCTGTCCACATG
GATCGCGCACACTCGTTTAGGTGGTCTGCCATTAGTGAAAACCTGTTTGCAACCACTGGATATC
CTGGCAAAATGTCCAGTCAGTTTCAGATTCATCATTTAGGACACTCTCAGCCCATCCTCATTGG
CTCTGTACCTGTCGGATCTGGTCTTTCCTGGCACAGAACACTCCCGCTGTGTGCAGTTGGAGGA
GACCATAAGCTCTTGTTCTGGGTGACAGAAATATGATTTCCCTCTGTATTTTTAATCCTACACT
TTGTATTTTTAGTATATATTTTGGAAAAAATACTTATTTTTATATCAAACATACTGTAAGTCTA
GAAATGCCTCAGTTGTCTTTTCTGATAAATAAAATGATAAAGACTTCTTGAAAATTA

hide sequence

RefSeq Acc Id:

XM_006241198 ⟹ XP_006241260

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,573,704 - 22,609,622 (+)	NCBI
Rnor_6.0	7	28,715,299 - 28,750,978 (+)	NCBI
Rnor_5.0	7	28,825,280 - 28,860,960 (+)	NCBI

Sequence:

show sequence

CGACCCGGAAGCAGAGCGGGCGCTCGCCGCGGCCGCCCTTGGTCATGAGAGTGGTACCCAGGTC
GCCTCCCCTGCATTAGTTTTGTGACAGCCAATAAAAGAACATTTTGATCCTCACCACTGCTCAA
GCTTTGGAATACAAGATGAAGCAAGACGTTACAAGAAACGCTGCCTATACGGTGGATTGTGAAG
ATTATGTGCATGTGGTAGAATTTAATCCCTTTGAGAGTGGAGAGTCGGGAAACCTGATCGCATA
TGGCGGCAGTAATTATGTGGTTGTTGGCATGTGTATGTTTCAGGAGGAAGGAACAGACACTGAA
GGAATTCAGTACAAAACACTACGAACATTTCACCATGGAGTCCGAGTTGATGGCATTGCCTGGA
GCCCAGAGACCAAGCTTGATTCGCTGCCTCCCGTAATCAAATTTTGTACGTCAGCCGCTGATAT
GAAGATTAGATTATTTACTTCAGACCTTCAAGATAAAAATGAATATAAGGTTTTGGAGGGCCAC
TCGGATTTCATTAATGATTTGGTGTTTCATCCCAGAGAAGGCCAGGAAATCGCGAGTGTGAGTG
ACGACCATACCTGCAGGATTTGGAGCTTGGAAGGAAAGCAGACAGCTCATTTTCTTCTTCATTC
TCCTGGAATGAGTGTATGCTGGCATCCTGAGGAAACTTTCAAGCTAATGGTCGCAGAGAAGAAC
GGAACAATCCGGTTTTATGATCTAATGGCCCAGCAGGCAATTTTATCTCTTCAGTCAGAACAGA
CACCATTAATGTCAGCACACTGGTGCTTGAAAAACACCTTCAAAGTTGGTGCTGTTGCAGGAAA
TGATTGGATTATCTGGGATATCACTCGGTCCAGTTATCCTCAAGAGACAAGACCTGTCCACATG
GATCGCGCACACTCGTTTAGGTGGTCTGCCATTAGTGAAAACCTGTTTGCAACCACTGGATATC
CTGGCAAAATGTCCAGTCAGTTTCAGATTCATCATTTAGGACACTCTCAGCTCTGACAAAACAA
AACTCCAATGTTGTTTTGAAGTCCAGAAACGAAGCTCCAAGAGGAAATGTGGATGCTGAGCCGC
TAGGATCGGTCTAAATAACTGCATGAAGCTATGATTCAAAGTAACCTGACTGCTTTCAGAAGTC
CAGGTGCTGAGTCACCTACAGAAAAAGCCAGGAGAGGTTAATGAAAAGCAGCTGCATTTCTTAC
AACAGACCTTCCCTTTAAAGGTGGGCAGAGCTAAGCAAAGGCTGGCGACTGAGGCCTGCTGAGT
TTCTCCACACAAATGGCGGGTCTGATGCTGAGTTCAGATCTCCAGAACCATTTAAACTAGTTCA
TCCTCAGCTGCTTGCCTTGCCTTGCCTTGCCTTCATGAGAGAAGCCTCAATAAAGGCTATGGTG
CTGTCTTGTCTCCTGAACAAGGTCTAGCATTTCCCTTAACTGCATGACACGGCATCTTGTCTCC
ATTTTTTGCTTGGGATGAATGCAGAAAATACCTCTCCCTAGAGCAGAGTTAGCATTGCCACAGC
ATTGATATGAGCTGCTAGAACATTGCCAAAGATGTGTCTGTTGGAATCACTCTCGAAAGAATTA
TGTCTCCTTTAAGGTGCTGGAGGCCAGGGAACTTTGACTCTCTGACAAGTGTGAGACCCTTCCC
TGGTGCTTTGGCTGCCTTGAGCAGAAAAAACTGTCAGCTAAGCAGCCCACTGGATCACCCTCCT
GCCAGCAGTGGCCACTCTGAGGAGGCTAACCAGTAACCACAGCTGCTTGCTATTGTATTAAAGG
CCCTGTCCCAGTCGTGATTGTTTTAAACATCTCAAACAGACCTTTGTGCCTTCAAAAAACCCCT
GGTCAACTGGAGGTTCAGTTATTTTTCAGCCCAAAGCAAAGGAGCCATAGTGCCCCAAATGGCG
CGGCAGATGGTCTCTGACCGGTGTACGCCCTGTTGGTCATTTCTATGGTAAATGCATGCATGCC
CTTTCTAATGGTAGAAGCACACTGTTGGGCTCACTTTCTGAGTTAGCCAGAAGACTACCTCTTG
TATTGCCCTGCGATGTGCAACCTGAAGACCTTAGGAGGTTTCTCTAGAGAGGTCTTTCCTGGCC
TGAGTTTGATTTCTCACCCTTAGCAGAGTGAAGGAAGGACAGCAGCAGACGCTTCAGCAGGGGA
CAGTGGTGCTGGGGAGCTCCCGAGAACAGCCGTGGCAGAAATGGTACAGGATGAGTTGGGCAGA
AGCAAAGAAAATGAGGGCCGAGAAGAACTAGAGACTGGGCACTTCAGGCTTCGCTTACTGGAGG
ACTCCCAGAGATTATCCAAGCCTAAAGACCAAGATCCTAACACCCTGGGCTCAAGAGCTGTGAC
TCTGGACGTTCACAGCCTGTATGAGAGAGCAGCACTAGAAGATGTCACATCACTTCTGCTTGCT
GCTCGCTGAAGCCAAAGGTGACAACTGACAGGGCTGCTGGTCCTTAAGCCCCAGAGCTATAAGC
CTTCAGCCAGAAGGAGCTATAAGCCTTCAGCCAGAAGGAGCTATAAGCCTTCAGCCAGAAGGAG
CTATAAGCCTTCAGCCAGAAGGAGCTATAAGCCTTCAGCCAGAAGGAGCTATAAGCCTTCAGCC
AGAAGGAGCTATAAGCCTTCAGCCAGAAGGAGCTATAAGCCTTCAGCCAGAAGGAGCTATAAGC
CTTCAGCCAGAAGGAGCTATAAGCCTTCAGCCAGAAGGAGCTATAAGCCTTCAGCCAGAAGGAG
CTATAAGCCTTCAGCCAGAAGGAGCTATAAGCCACTGGTCTGTGAATCCAGGCTATAGGACTTG
GGTGCTGTGGTAGTTTAAATAGGTTTGGTCCACAAAGATTCATGCGTTTGAGCACTTGGCATAG
GGAGTGGCACTATTAGAAGGTGTGGCCTTATTGGAGGAGGTATATCACTGTGTGGGTGGACTTT
GAGGGCTCCTATGTTCAGGCTCCATCAAGTGGGGAATCTGATCTTTCACCTAGCTGCCTTTGGT
TCAAGATGCAGAGCTCTTGGCGCTTCCAGCACCGTGTCTGTCTGCAGGCTGTTATGCTTCCAGC
CATGATGATAATGGACTGAACTTCTGAAACTGTAAACCAGCCCCAATAAATGTGTGACTTTATA
AGA

hide sequence

RefSeq Acc Id:

XM_039078684 ⟹ XP_038934612

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,559,314 - 22,601,970 (+)	NCBI

RefSeq Acc Id:

XM_039078685 ⟹ XP_038934613

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,556,544 - 22,601,970 (+)	NCBI

RefSeq Acc Id:

XM_039078686 ⟹ XP_038934614

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,556,544 - 22,601,970 (+)	NCBI

RefSeq Acc Id:

XR_005486570

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	7	22,573,704 - 22,609,622 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100245	(Get FASTA)	NCBI Sequence Viewer
	XP_006241259	(Get FASTA)	NCBI Sequence Viewer
	XP_006241260	(Get FASTA)	NCBI Sequence Viewer
	XP_038934612	(Get FASTA)	NCBI Sequence Viewer
	XP_038934613	(Get FASTA)	NCBI Sequence Viewer
	XP_038934614	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI61937	(Get FASTA)	NCBI Sequence Viewer
	EDM17014	(Get FASTA)	NCBI Sequence Viewer
	EDM17015	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001100245 ⟸ NM_001106775

- UniProtKB:

G3V6M8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKQDVTRNAAYTVDCEDYVHVVEFNPFESGESGNLIAYGGSNYVVVGMCMFQEEGTDTEGIQYK
TLRTFHHGVRVDGIAWSPETKLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHSDFIN
DLVFHPREGQEIASVSDDHTCRIWSLEGKQTAHFLLHSPGMSVCWHPEETFKLMVAEKNGTIRF
YDLMAQQAILSLQSEQTPLMSAHWCLKNTFKVGAVAGNDWIIWDITRSSYPQETRPVHMDRAHS
FRWSAISENLFATTGYPGKMSSQFQIHHLGHSQPILIGSVPVGSGLSWHRTLPLCAVGGDHKLL
FWVTEI

hide sequence

RefSeq Acc Id:

XP_006241260 ⟸ XM_006241198

- Peptide Label:

isoform X2

- Sequence:

show sequence

MKQDVTRNAAYTVDCEDYVHVVEFNPFESGESGNLIAYGGSNYVVVGMCMFQEEGTDTEGIQYK
TLRTFHHGVRVDGIAWSPETKLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHSDFIN
DLVFHPREGQEIASVSDDHTCRIWSLEGKQTAHFLLHSPGMSVCWHPEETFKLMVAEKNGTIRF
YDLMAQQAILSLQSEQTPLMSAHWCLKNTFKVGAVAGNDWIIWDITRSSYPQETRPVHMDRAHS
FRWSAISENLFATTGYPGKMSSQFQIHHLGHSQL

hide sequence

RefSeq Acc Id:	XP_006241259 ⟸ XM_006241197
- Peptide Label:	isoform X1
- UniProtKB:	G3V6M8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKQDVTRNAAYTVDCEDYVHVVEFNPFESGESGNLIAYGGSNYVVVGMCMFQEEGTDTEGIQYK TLRTFHHGVRVDGIAWSPETKLDSLPPVIKFCTSAADMKIRLFTSDLQDKNEYKVLEGHSDFIN DLVFHPREGQEIASVSDDHTCRIWSLEGKQTAHFLLHSPGMSVCWHPEETFKLMVAEKNGTIRF YDLMAQQAILSLQSEQTPLMSAHWCLKNTFKVGAVAGNDWIIWDITRSSYPQETRPVHMDRAHS FRWSAISENLFATTGYPGKMSSQFQIHHLGHSQPILIGSVPVGSGLSWHRTLPLCAVGGDHKLL FWVTEI hide sequence

RefSeq Acc Id:

ENSRNOP00000072699 ⟸ ENSRNOT00000079168

RefSeq Acc Id:

ENSRNOP00000006760 ⟸ ENSRNOT00000006760

RefSeq Acc Id:

ENSRNOP00000075343 ⟸ ENSRNOT00000089161

RefSeq Acc Id:	XP_038934613 ⟸ XM_039078685
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038934614 ⟸ XM_039078686
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038934612 ⟸ XM_039078684
- Peptide Label:	isoform X1

Protein Domains

WD_REPEATS_REGION

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695123

Promoter ID:

EPDNEW_R5648

Type:

initiation region

Name:

Nup37_1

Description:

nucleoporin 37

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	28,715,311 - 28,715,371	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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CSV

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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CSV

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307774	AgrOrtholog
Ensembl Genes	ENSRNOG00000004727	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006760	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000072699	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000075343	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006760	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000079168	UniProtKB/TrEMBL
	ENSRNOT00000089161	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9022830	IMAGE-MGC_LOAD
InterPro	NUP37	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:299706	UniProtKB/TrEMBL
MGC_CLONE	MGC:187721	IMAGE-MGC_LOAD
NCBI Gene	299706	ENTREZGENE
PANTHER	PTHR22806	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PhenoGen	Nup37	PhenoGen
PROSITE	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	B1WBY6_RAT	UniProtKB/TrEMBL
	G3V6M8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Nup37	nucleoporin 37	Nup37_predicted	nucleoporin 37 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Nup37_predicted	nucleoporin 37 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)