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Gene: Cfd (complement factor D) Rattus norvegicus
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Symbol: Cfd
Name: complement factor D
Description: Exhibits endopeptidase activity. Involved in Notch signaling pathway. Localizes to the extracellular space. Used to study arthus reaction. Biomarker of obesity. Orthologous to human CFD (complement factor D); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; INTERACTS WITH (RS)-amphetamine; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adipsin; Adn; C3 convertase activator; complement factor D (adipsin); D component of complement (adipsin); Df; endogenous vascular elastase; EVE; properdin factor D
Orthologs:
Homo sapiens (human) : CFD (complement factor D)  HGNC  Alliance
Mus musculus (house mouse) : Cfd (complement factor D (adipsin))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cfd (complement factor D)
Pan paniscus (bonobo/pygmy chimpanzee) : CFD (complement factor D)
Canis lupus familiaris (dog) : CFD (complement factor D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cfd (complement factor D)
Sus scrofa (pig) : CFD (complement factor D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0712,634,216 - 12,635,939 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0712,803,938 - 12,805,661 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,325,538 - 11,327,261 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1711,325,546 - 11,327,251 (-)NCBI
Celera77,987,896 - 7,989,620 (-)NCBICelera
Cytogenetic Map7q11NCBI
RH 3.4 Map741.1RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cfd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2498
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.