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Gene: Lum (lumican) Rattus norvegicus
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Symbol: Lum
Name: lumican
Description: Predicted to have collagen binding activity. Involved in cartilage development; response to growth factor; and response to organic cyclic compound. Localizes to the extracellular matrix. Biomarker of ureteral obstruction. Human ortholog(s) of this gene implicated in carotid artery disease; coronary artery disease; and pancreatic cancer. Orthologous to human LUM (lumican); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: keratan sulfate proteoglycan lumican; KSPG lumican
Orthologs:
Homo sapiens (human) : LUM (lumican)  HGNC  Alliance
Mus musculus (house mouse) : Lum (lumican)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lum (lumican)
Pan paniscus (bonobo/pygmy chimpanzee) : LUM (lumican)
Canis lupus familiaris (dog) : LUM (lumican)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lum (lumican)
Sus scrofa (pig) : LUM (lumican)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0738,820,058 - 38,826,862 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0738,861,407 - 38,868,211 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4735,083,480 - 35,090,284 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1735,103,750 - 35,110,554 (+)NCBI
Celera729,396,589 - 29,403,393 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lum
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620984
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.