Or6c6f (olfactory receptor family 6 subfamily C member 6F) - Rat Genome Database

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Gene: Or6c6f (olfactory receptor family 6 subfamily C member 6F) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or6c6f
Name: olfactory receptor family 6 subfamily C member 6F
RGD ID: 1333970
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR6C6 (olfactory receptor family 6 subfamily C member 6); INTERACTS WITH cadmium dichloride.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC103690036; olfactory receptor 6C6-like; olfactory receptor 922; olfactory receptor gene Olr922; olfactory receptor Olr922; Olr922
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr873,510,672 - 3,513,419 (-)NCBIGRCr8
mRatBN7.272,861,664 - 2,864,411 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl72,861,309 - 2,864,319 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx75,730,943 - 5,731,887 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.077,606,609 - 7,607,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.01123,062,470 - 23,065,217 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
RGSC_v3.474,112,930 - 4,113,874NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.174,112,929 - 4,113,874NCBI
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or6c6f
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:14
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000043396
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat


Expression

RNA-SEQ Expression

reproductive system
1

Sequence


Ensembl Acc Id: ENSRNOT00000043396   ⟹   ENSRNOP00000040908
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1123,062,470 - 23,063,414 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000073630   ⟹   ENSRNOP00000064471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl72,861,309 - 2,864,319 (-)Ensembl
Rnor_6.0 Ensembl716,067,879 - 16,068,823 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108737   ⟹   ENSRNOP00000097260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl72,861,335 - 2,864,319 (-)Ensembl
RefSeq Acc Id: NM_001000705   ⟹   NP_001000705
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr873,510,672 - 3,511,616 (-)NCBI
mRatBN7.272,861,664 - 2,862,608 (-)NCBI
Rnor_6.01123,062,470 - 23,063,414 (-)NCBI
Rnor_5.01126,698,042 - 26,698,986 (-)NCBI
RGSC_v3.474,112,930 - 4,113,874 (-)RGD
Sequence:
RefSeq Acc Id: XM_017598041   ⟹   XP_017453530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr873,510,672 - 3,513,419 (-)NCBI
mRatBN7.272,861,664 - 2,864,411 (-)NCBI
Rnor_6.01123,062,470 - 23,065,217 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001000705 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453530 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064471.3
  ENSRNOP00000097260.1
RefSeq Acc Id: NP_001000705   ⟸   NM_001000705
- UniProtKB: A0A8I6AU47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453530   ⟸   XM_017598041
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AU47 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040908   ⟸   ENSRNOT00000043396
Ensembl Acc Id: ENSRNOP00000064471   ⟸   ENSRNOT00000073630
Ensembl Acc Id: ENSRNOP00000097260   ⟸   ENSRNOT00000108737
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1W0-F1-model_v2 AlphaFold D4A1W0 1-314 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333970 AgrOrtholog
BioCyc Gene G2FUF-35266 BioCyc
Ensembl Genes ENSRNOG00000047837 Ensembl
  ENSRNOG00000061704 Ensembl
  ENSRNOG00000070603 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073630.3 UniProtKB/TrEMBL
  ENSRNOT00000108737.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
NCBI Gene 404948 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 6C6 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6c6f PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047837 RatGTEx
  ENSRNOG00000061704 RatGTEx
  ENSRNOG00000070603 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6AU47 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8YLY6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6c6f  olfactory receptor family 6 subfamily C member 6F  Olr922  olfactory receptor 922  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr922  olfactory receptor 922  LOC103690036  olfactory receptor 6C6-like  Data merged from RGD:9097616 737654 PROVISIONAL
2014-08-25 LOC103690036  olfactory receptor 6C6-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr922  olfactory receptor 922   Olr922_predicted  olfactory receptor 922 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr922_predicted  olfactory receptor 922 (predicted)      Symbol and Name status set to approved 70820 APPROVED