Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pip4k2c | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Pip4k2c (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PIP4K2C mRNA | CTD | PMID:22206623 | Pip4k2c | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Pip4k2c (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PIP4K2C mRNA | CTD | PMID:22206623 | Pip4k2c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PIP4K2C mRNA | CTD | PMID:15034205 | Pip4k2c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PIP4K2C mRNA | CTD | PMID:33387578 | Pip4k2c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PIP4K2C mRNA | CTD | PMID:21570461 and PMID:24680724 | Pip4k2c | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Pip4k2c (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIP4K2C mRNA] | CTD | PMID:15034205 | Pip4k2c | Rat | 2,4,6-tribromophenol | decreases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Pip4k2c | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of PIP4K2C mRNA | CTD | PMID:21346803 | Pip4k2c | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of PIP4K2C protein | CTD | PMID:31675489 | Pip4k2c | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of PIP4K2C mRNA | CTD | PMID:28959563 | Pip4k2c | Rat | aflatoxin B1 | decreases methylation | ISO | PIP4K2C (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PIP4K2C gene | CTD | PMID:27153756 | Pip4k2c | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PIP4K2C mRNA | CTD | PMID:16483693 | Pip4k2c | Rat | aristolochic acid A | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PIP4K2C mRNA and aristolochic acid I results in increased expression of PIP4K2C protein | CTD | PMID:33212167 | Pip4k2c | Rat | arsenous acid | increases response to substance | ISO | PIP4K2C (Homo sapiens) | 6480464 | PIP4K2C protein results in increased susceptibility to Arsenic Trioxide | CTD | PMID:22496355 | Pip4k2c | Rat | benzo[a]pyrene | decreases expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of PIP4K2C mRNA | CTD | PMID:15034205 | Pip4k2c | Rat | benzo[a]pyrene | multiple interactions | ISO | Pip4k2c (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of PIP4K2C mRNA] | CTD | PMID:15034205 | Pip4k2c | Rat | beta-naphthoflavone | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PIP4K2C mRNA | CTD | PMID:18164116 | Pip4k2c | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PIP4K2C mRNA | CTD | PMID:25181051 | Pip4k2c | Rat | bisphenol A | decreases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PIP4K2C protein | CTD | PMID:31675489 | Pip4k2c | Rat | bisphenol A | affects expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | bisphenol A affects the expression of PIP4K2C mRNA | CTD | PMID:30903817 | Pip4k2c | Rat | butyric acid | increases expression | EXP | | 6480464 | Butyric Acid results in increased expression of PIP4K2C mRNA | CTD | PMID:12800193 | Pip4k2c | Rat | calcitriol | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Calcitriol results in increased expression of PIP4K2C mRNA | CTD | PMID:26485663 | Pip4k2c | Rat | CGP 52608 | multiple interactions | ISO | PIP4K2C (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PIP4K2C gene] | CTD | PMID:28238834 | Pip4k2c | Rat | cyclosporin A | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PIP4K2C mRNA | CTD | PMID:25562108 | Pip4k2c | Rat | decabromodiphenyl ether | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of PIP4K2C protein | CTD | PMID:31675489 | Pip4k2c | Rat | diarsenic trioxide | increases response to substance | ISO | PIP4K2C (Homo sapiens) | 6480464 | PIP4K2C protein results in increased susceptibility to Arsenic Trioxide | CTD | PMID:22496355 | Pip4k2c | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of PIP4K2C mRNA | CTD | PMID:21266533 | Pip4k2c | Rat | dicrotophos | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | dicrotophos results in increased expression of PIP4K2C mRNA | CTD | PMID:28302478 | Pip4k2c | Rat | diethylstilbestrol | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of PIP4K2C mRNA | CTD | PMID:36621641 | Pip4k2c | Rat | ethanol | affects splicing | ISO | Pip4k2c (Mus musculus) | 6480464 | Ethanol affects the splicing of PIP4K2C mRNA | CTD | PMID:30319688 | Pip4k2c | Rat | ethyl methanesulfonate | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of PIP4K2C mRNA | CTD | PMID:23649840 | Pip4k2c | Rat | folic acid | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Folic Acid results in increased expression of PIP4K2C mRNA | CTD | PMID:21867686 | Pip4k2c | Rat | folic acid | multiple interactions | ISO | Pip4k2c (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PIP4K2C mRNA | CTD | PMID:22206623 | Pip4k2c | Rat | formaldehyde | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of PIP4K2C mRNA | CTD | PMID:23649840 | Pip4k2c | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PIP4K2C mRNA | CTD | PMID:33387578 | Pip4k2c | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of PIP4K2C mRNA | CTD | PMID:24136188 | Pip4k2c | Rat | hydrogen cyanide | decreases expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of PIP4K2C mRNA | CTD | PMID:33914522 | Pip4k2c | Rat | ivermectin | decreases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PIP4K2C protein | CTD | PMID:32959892 | Pip4k2c | Rat | methyl methanesulfonate | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PIP4K2C mRNA | CTD | PMID:23649840 | Pip4k2c | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PIP4K2C mRNA | CTD | PMID:18164116 | Pip4k2c | Rat | paracetamol | affects expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Acetaminophen affects the expression of PIP4K2C mRNA | CTD | PMID:15606129 and PMID:17562736 | Pip4k2c | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PIP4K2C mRNA | CTD | PMID:33387578 | Pip4k2c | Rat | paracetamol | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PIP4K2C mRNA | CTD | PMID:22230336 | Pip4k2c | Rat | potassium cyanide | increases expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of PIP4K2C mRNA | CTD | PMID:33914522 | Pip4k2c | Rat | potassium dichromate | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of PIP4K2C protein | CTD | PMID:23718831 | Pip4k2c | Rat | Propiverine | affects binding | EXP | | 6480464 | propiverine binds to PIP4K2C protein | CTD | PMID:29273565 | Pip4k2c | Rat | resveratrol | increases expression | ISO | Pip4k2c (Mus musculus) | 6480464 | resveratrol results in increased expression of PIP4K2C protein | CTD | PMID:25505154 | Pip4k2c | Rat | sodium arsenite | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PIP4K2C mRNA | CTD | PMID:38568856 | Pip4k2c | Rat | sodium arsenite | decreases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PIP4K2C protein | CTD | PMID:30528433 | Pip4k2c | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of PIP4K2C mRNA | CTD | PMID:19281266 | Pip4k2c | Rat | sunitinib | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PIP4K2C mRNA | CTD | PMID:31533062 | Pip4k2c | Rat | tanespimycin | multiple interactions | ISO | PIP4K2C (Homo sapiens) | 6480464 | [tanespimycin co-treated with VER 155008] results in increased expression of PIP4K2C protein | CTD | PMID:31370342 | Pip4k2c | Rat | trichostatin A | affects expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | trichostatin A affects the expression of PIP4K2C mRNA | CTD | PMID:28542535 | Pip4k2c | Rat | urethane | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Urethane results in increased expression of PIP4K2C mRNA | CTD | PMID:28818685 | Pip4k2c | Rat | valproic acid | affects expression | ISO | Pip4k2c (Mus musculus) | 6480464 | Valproic Acid affects the expression of PIP4K2C mRNA | CTD | PMID:17963808 | Pip4k2c | Rat | valproic acid | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PIP4K2C mRNA | CTD | PMID:23179753 more ... | Pip4k2c | Rat | valproic acid | affects expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PIP4K2C mRNA | CTD | PMID:25979313 | Pip4k2c | Rat | vitamin E | increases expression | ISO | PIP4K2C (Homo sapiens) | 6480464 | Vitamin E results in increased expression of PIP4K2C mRNA | CTD | PMID:19244175 | |