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Gene: Ptprq (protein tyrosine phosphatase, receptor type, Q) Rattus norvegicus
Symbol: Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Description: Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; hematopoietic progenitor cell differentiation; and vestibular receptor cell morphogenesis. Predicted to localize to the stereocilium bundle. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Orthologous to human PTPRQ (protein tyrosine phosphatase receptor type Q); PARTICIPATES IN auditory mechanotransduction pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glomerular mesangial cell receptor protein-tyrosine phosphatase; glomerular mesangial cell receptor protein-tyrosine phosphatase precursor; phosphatidylinositol phosphatase PTPRQ; phosphotidylinositol phosphatase PTPRQ; protein-tyrosine phosphatase receptor-type expressed by glomerular mesangial cells protein 1; PTP-RQ; R-PTP-Q; receptor-type tyrosine-protein phosphatase Q; rPTP-GMC1
Homo sapiens (human) : PTPRQ (protein tyrosine phosphatase receptor type Q)  HGNC  Alliance
Mus musculus (house mouse) : Ptprq (protein tyrosine phosphatase, receptor type, Q)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprq (protein tyrosine phosphatase receptor type Q)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Canis lupus familiaris (dog) : PTPRQ (protein tyrosine phosphatase receptor type Q)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprq (protein tyrosine phosphatase receptor type Q)
Sus scrofa (pig) : PTPRQ (protein tyrosine phosphatase receptor type Q)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0749,763,657 - 50,034,932 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0749,939,446 - 50,045,544 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0749,773,565 - 49,852,881 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4746,224,075 - 46,400,107 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1746,244,345 - 46,420,378 (-)NCBI
Celera739,709,561 - 39,889,789 (-)NCBICelera
Cytogenetic Map7q21NCBI
RH 3.4 Map7352.32RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ptprq
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620779
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.