Cand1 (cullin-associated and neddylation-dissociated 1) - Rat Genome Database

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Gene: Cand1 (cullin-associated and neddylation-dissociated 1) Rattus norvegicus
Analyze
Symbol: Cand1
Name: cullin-associated and neddylation-dissociated 1
RGD ID: 620479
Description: Enables TBP-class protein binding activity. Involved in positive regulation of RNA polymerase II transcription preinitiation complex assembly. Located in nucleus. Orthologous to human CAND1 (cullin associated and neddylation dissociated 1); PARTICIPATES IN neddylation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cullin associated and neddylation disassociated 1; cullin-associated and neddylation-dissociated protein 1; cullin-associated NEDD8-dissociated protein 1; p120 CAND1; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TBP-interacting protein TIP120A; Tip120; Tip120A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2754,681,114 - 54,719,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx756,587,617 - 56,625,505 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0758,790,753 - 58,828,639 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0758,568,597 - 58,606,483 (-)NCBIRnor_WKY
Rnor_6.0762,124,362 - 62,162,451 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0762,113,404 - 62,151,493 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4758,461,205 - 58,499,092 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1758,481,934 - 58,519,822 (-)NCBI
Celera751,445,526 - 51,483,413 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cullin-RING ubiquitin ligase complex  (ISO,ISS)
cytoplasm  (ISO,ISS)
cytosol  (IEA,ISO)
Golgi apparatus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA)
nucleus  (IDA)
nucleus  (ISO,ISS)
ubiquitin ligase complex  (ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. TATA-Binding protein-interacting protein 120, TIP120, stimulates three classes of eukaryotic transcription via a unique mechanism. Makino Y, etal., Mol Cell Biol. 1999 Dec;19(12):7951-60.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Parry G and Estelle M, Semin Cell Dev Biol. 2004 Apr;15(2):221-9.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Molecular cloning of a novel 120-kDa TBP-interacting protein. Yogosawa S, etal., Biochem Biophys Res Commun 1996 Dec 13;229(2):612-7.
9. Induced expression, localization, and chromosome mapping of a gene for the TBP-interacting protein 120A. Yogosawa S, etal., Biochem Biophys Res Commun 1999 Dec 9;266(1):123-8.
Additional References at PubMed
PMID:10441524   PMID:10526239   PMID:12609982   PMID:15537541   PMID:19056867   PMID:19946888   PMID:20458337   PMID:21249194   PMID:21630459   PMID:22405651   PMID:23533145   PMID:26316108  
PMID:29367474   PMID:29476059   PMID:32357304   PMID:34974108  


Genomics

Comparative Map Data
Cand1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2754,681,114 - 54,719,002 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx756,587,617 - 56,625,505 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0758,790,753 - 58,828,639 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0758,568,597 - 58,606,483 (-)NCBIRnor_WKY
Rnor_6.0762,124,362 - 62,162,451 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0762,113,404 - 62,151,493 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4758,461,205 - 58,499,092 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1758,481,934 - 58,519,822 (-)NCBI
Celera751,445,526 - 51,483,413 (-)NCBICelera
Cytogenetic Map7q22NCBI
CAND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381267,269,358 - 67,319,953 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1267,269,358 - 67,319,953 (+)EnsemblGRCh38hg38GRCh38
GRCh371267,663,138 - 67,713,733 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361265,949,416 - 65,994,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 341265,949,415 - 65,994,187NCBI
Celera1267,327,070 - 67,372,407 (+)NCBICelera
Cytogenetic Map12q14.3-q15NCBI
HuRef1264,713,845 - 64,759,496 (+)NCBIHuRef
CHM1_11267,630,340 - 67,675,666 (+)NCBICHM1_1
T2T-CHM13v2.01267,248,745 - 67,299,478 (+)NCBIT2T-CHM13v2.0
Cand1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910119,034,717 - 119,075,960 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10119,035,160 - 119,075,960 (-)EnsemblGRCm39 Ensembl
GRCm3810119,198,812 - 119,240,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10119,199,255 - 119,240,055 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710118,635,868 - 118,677,111 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610118,601,872 - 118,724,036 (-)NCBIMGSCv36mm8
Celera10121,557,633 - 121,598,810 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1067.08NCBI
Cand1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545813,815,819 - 13,850,007 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545813,815,819 - 13,850,007 (+)NCBIChiLan1.0ChiLan1.0
CAND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11222,099,962 - 22,145,013 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1222,099,962 - 22,145,013 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01221,592,833 - 21,638,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CAND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1109,652,176 - 9,683,373 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl109,641,732 - 9,680,118 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha109,571,760 - 9,612,014 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0109,755,181 - 9,795,481 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl109,755,061 - 9,794,999 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1109,631,961 - 9,672,240 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0109,877,617 - 9,917,882 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0109,999,578 - 10,039,865 (+)NCBIUU_Cfam_GSD_1.0
Cand1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494548,854,528 - 48,892,090 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365455,218,407 - 5,255,245 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365455,217,947 - 5,255,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl531,675,574 - 31,696,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1531,657,508 - 31,700,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2534,955,840 - 34,994,724 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11162,923,198 - 62,968,789 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1162,922,885 - 62,966,994 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037182,746,329 - 182,791,692 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cand1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248021,014,515 - 1,049,561 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248021,010,749 - 1,049,253 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cand1
90 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:44
Count of miRNA genes:38
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000010720
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat

Markers in Region
AI195005  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,681,357 - 54,681,480 (+)MAPPERmRatBN7.2
Rnor_6.0762,124,606 - 62,124,728NCBIRnor6.0
Rnor_5.0762,113,648 - 62,113,770UniSTSRnor5.0
RGSC_v3.4758,461,449 - 58,461,571UniSTSRGSC3.4
Celera751,445,770 - 51,445,892UniSTS
Cytogenetic Map7q22UniSTS
RH138241  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,719,336 - 54,719,472 (+)MAPPERmRatBN7.2
Rnor_6.0762,162,786 - 62,162,921NCBIRnor6.0
Rnor_5.0762,151,828 - 62,151,963UniSTSRnor5.0
RGSC_v3.4758,499,427 - 58,499,562UniSTSRGSC3.4
Celera751,483,748 - 51,483,883UniSTS
RH 3.4 Map7489.3UniSTS
Cytogenetic Map7q22UniSTS
RH139433  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,680,931 - 54,681,056 (+)MAPPERmRatBN7.2
Rnor_6.0762,124,180 - 62,124,304NCBIRnor6.0
Rnor_5.0762,113,222 - 62,113,346UniSTSRnor5.0
RGSC_v3.4758,461,023 - 58,461,147UniSTSRGSC3.4
Celera751,445,344 - 51,445,468UniSTS
RH 3.4 Map7489.3UniSTS
Cytogenetic Map7q22UniSTS
BI275731  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2754,681,369 - 54,681,548 (+)MAPPERmRatBN7.2
Rnor_6.0762,124,618 - 62,124,796NCBIRnor6.0
Rnor_5.0762,113,660 - 62,113,838UniSTSRnor5.0
RGSC_v3.4758,461,461 - 58,461,639UniSTSRGSC3.4
Celera751,445,782 - 51,445,960UniSTS
RH 3.4 Map7488.0UniSTS
Cytogenetic Map7q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 57 41 19 41 8 8 74 35 41 11 8
Low 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010720   ⟹   ENSRNOP00000010720
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl754,680,900 - 54,718,993 (-)Ensembl
Rnor_6.0 Ensembl762,124,362 - 62,162,453 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111987   ⟹   ENSRNOP00000086186
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl754,680,900 - 54,698,264 (-)Ensembl
RefSeq Acc Id: NM_054004   ⟹   NP_446456
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2754,681,114 - 54,719,002 (-)NCBI
Rnor_6.0762,124,362 - 62,162,451 (-)NCBI
Rnor_5.0762,113,404 - 62,151,493 (-)NCBI
RGSC_v3.4758,461,205 - 58,499,092 (-)RGD
Celera751,445,526 - 51,483,413 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446456 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAA13432 (Get FASTA)   NCBI Sequence Viewer  
  EDM16585 (Get FASTA)   NCBI Sequence Viewer  
  P97536 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446456   ⟸   NM_054004
- UniProtKB: P97536 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000010720   ⟸   ENSRNOT00000010720
RefSeq Acc Id: ENSRNOP00000086186   ⟸   ENSRNOT00000111987
Protein Domains
TATA-binding protein interacting (TIP20)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97536-F1-model_v2 AlphaFold P97536 1-1230 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695221
Promoter ID:EPDNEW_R5746
Type:initiation region
Name:Cand1_1
Description:cullin-associated and neddylation-dissociated 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0762,162,447 - 62,162,507EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620479 AgrOrtholog
BioCyc Gene G2FUF-33932 BioCyc
Ensembl Genes ENSRNOG00000007834 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000010720 ENTREZGENE
  ENSRNOP00000010720.3 UniProtKB/Swiss-Prot
  ENSRNOP00000086186.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010720 ENTREZGENE
  ENSRNOT00000010720.4 UniProtKB/Swiss-Prot
  ENSRNOT00000111987.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAND1/CAND2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TATA-bd_TIP120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117152 UniProtKB/Swiss-Prot
NCBI Gene 117152 ENTREZGENE
PANTHER CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12696 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TIP120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cand1 PhenoGen
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A6C9_RAT UniProtKB/TrEMBL
  CAND1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cand1  cullin-associated and neddylation-dissociated 1  Cand1  cullin associated and neddylation disassociated 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Cand1  cullin associated and neddylation disassociated 1  Tip120A  TBP-interacting protein 120A  Symbol and Name updated 1299863 APPROVED
2005-07-08 Tip120A  TBP-interacting protein 120A      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tip120A  TBP-interacting protein 120A      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the nucleus 634479
gene_protein 120-kD protein 634479