(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of IGF1 mRNA] CTD PMID:31150632 (-)-anisomycin multiple interactions ISO RGD:70506 6480464 Anisomycin promotes the reaction [IGF1 protein results in increased phosphorylation of JUN protein] CTD PMID:11278392 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:70506 6480464 epigallocatechin gallate results in decreased expression of IGF1 mRNA CTD PMID:20346928 , PMID:20706672 (R)-noradrenaline multiple interactions EXP 6480464 Prazosin inhibits the reaction [IGF1 protein results in decreased susceptibility to Norepinephrine] CTD PMID:17184500 (R)-noradrenaline decreases response to substance EXP 6480464 IGF1 protein results in decreased susceptibility to Norepinephrine CTD PMID:17184500 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE increases expression EXP 6480464 Topotecan results in increased expression of IGF1 mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] affects the expression of IGF1 mRNA CTD PMID:25729387 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of IGF1 mRNA, Nicotine results in decreased expression of IGF1 protein CTD PMID:20960268 , PMID:22265867 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of IGF1 mRNA CTD PMID:29486207 (S)-nicotine multiple interactions EXP 6480464 rosiglitazone inhibits the reaction [Nicotine results in decreased expression of IGF1 protein] CTD PMID:20960268 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:10765 6480464 [Estradiol co-treated with 2 more ... CTD PMID:11509743 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases expression ISO RGD:10765 6480464 2 more ... CTD PMID:11509743 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases expression ISO RGD:10765 6480464 2 more ... CTD PMID:10965916 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of IGF1 mRNA CTD PMID:17984292 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression ISO RGD:10765 6480464 o, p'-DDT results in increased expression of IGF1 mRNA CTD PMID:24096037 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane increases expression EXP 6480464 o, p'-DDT results in increased expression of IGF1 mRNA CTD PMID:24096037 1,1-dichloroethene increases expression ISO RGD:10765 6480464 vinylidene chloride results in increased expression of IGF1 mRNA CTD PMID:26682919 1,2,3,4,7,8-Hexachlorodibenzodioxin decreases expression EXP 6480464 1 more ... CTD PMID:15703265 1,2-dichloroethane decreases expression ISO RGD:10765 6480464 ethylene dichloride results in decreased expression of IGF1 mRNA CTD PMID:28189721 1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in increased expression of IGF1 mRNA CTD PMID:27840820 1-methylphenanthrene multiple interactions ISO RGD:70506 6480464 [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGF1 mRNA CTD PMID:17690111 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE multiple interactions ISO RGD:70506 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of IGF1 protein CTD PMID:11172797 17alpha-ethynylestradiol multiple interactions ISO RGD:70506 6480464 [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of IGF1 protein more ... CTD PMID:11172797 , PMID:16002536 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of IGF1 mRNA CTD PMID:12075121 more ... 17alpha-ethynylestradiol increases expression ISO RGD:10765 6480464 Ethinyl Estradiol results in increased expression of IGF1 mRNA CTD PMID:16174780 more ... 17alpha-ethynylestradiol decreases expression ISO RGD:70506 6480464 Ethinyl Estradiol results in decreased expression of IGF1 protein CTD PMID:10843175 , PMID:15817916 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of IGF1 mRNA CTD PMID:16551644 17alpha-ethynylestradiol multiple interactions ISO RGD:10765 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IGF1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression ISO RGD:10765 6480464 Ethinyl Estradiol results in decreased expression of IGF1 mRNA CTD PMID:14976129 17alpha-ethynylestradiol affects expression ISO RGD:10765 6480464 Ethinyl Estradiol affects the expression of IGF1 mRNA CTD PMID:17555576 17beta-estradiol affects expression ISO RGD:70506 6480464 Estradiol affects the expression of IGF1 mRNA CTD PMID:21826169 17beta-estradiol increases expression ISO RGD:70506 6480464 Estradiol results in increased expression of IGF1 mRNA, Estradiol results in increased expression of IGF1 protein CTD PMID:15762036 more ... 17beta-estradiol increases abundance EXP 6480464 IGF1 protein results in increased abundance of Estradiol CTD PMID:21239528 17beta-estradiol increases abundance ISO RGD:70506 6480464 IGF1 protein results in increased abundance of Estradiol CTD PMID:19081562 more ... 17beta-estradiol decreases expression ISO RGD:10765 6480464 Estradiol results in decreased expression of IGF1 mRNA CTD PMID:11509743 , PMID:22467019 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IGF1 mRNA CTD PMID:15979666 more ... 17beta-estradiol multiple interactions EXP 6480464 2 more ... CTD PMID:16414171 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of IGF1 protein CTD PMID:11408345 17beta-estradiol multiple interactions ISO RGD:10765 6480464 [Estradiol co-treated with 2 more ... CTD PMID:11509743 more ... 17beta-estradiol increases secretion ISO RGD:70506 6480464 Estradiol results in increased secretion of IGF1 protein CTD PMID:15809018 17beta-estradiol decreases expression ISO RGD:70506 6480464 Estradiol results in decreased expression of IGF1 mRNA, Estradiol results in decreased expression of IGF1 protein CTD PMID:10843175 more ... 17beta-estradiol multiple interactions ISO RGD:70506 6480464 1 more ... CTD PMID:1332906 more ... 17beta-estradiol increases expression ISO RGD:10765 6480464 Estradiol results in increased expression of IGF1 mRNA CTD PMID:14664709 more ... 17beta-estradiol 3-benzoate affects expression EXP 6480464 estradiol 3-benzoate affects the expression of IGF1 mRNA CTD PMID:15925091 , PMID:19350480 17beta-estradiol 3-benzoate decreases expression EXP 6480464 estradiol 3-benzoate results in decreased expression of IGF1 mRNA CTD PMID:21190954 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:70506 6480464 Metribolone results in increased expression of IGF1 mRNA CTD PMID:25682698 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:70506 6480464 [Metribolone co-treated with tris(1 more ... CTD PMID:25682698 , PMID:26709203 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:70506 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1 mRNA], Flutamide inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1 mRNA] CTD PMID:16368782 17beta-hydroxy-5alpha-androstan-3-one multiple interactions EXP 6480464 resveratrol inhibits the reaction [Dihydrotestosterone results in increased secretion of IGF1 protein] CTD PMID:25667201 17beta-hydroxy-5alpha-androstan-3-one increases secretion EXP 6480464 Dihydrotestosterone results in increased secretion of IGF1 protein CTD PMID:25667201 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO RGD:10765 6480464 Dihydrotestosterone results in decreased expression of IGF1 mRNA CTD PMID:17023530 17beta-hydroxy-5alpha-androstan-3-one increases secretion ISO RGD:70506 6480464 Dihydrotestosterone results in increased secretion of IGF1 protein CTD PMID:16368782 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:70506 6480464 Dihydrotestosterone results in increased expression of IGF1 mRNA CTD PMID:16368782 , PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:19327374 , PMID:21190954 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:19464578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10765 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of IGF1 mRNA more ... CTD PMID:15034205 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:70506 6480464 [Tetrachlorodibenzodioxin co-treated with Estradiol] inhibits the reaction [IGF1 protein results in increased uptake of Thymidine], Tetrachlorodibenzodioxin inhibits the reaction [IGF1 protein results in decreased uptake of Thymidine] CTD PMID:1332906 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10765 6480464 Tetrachlorodibenzodioxin results in increased expression of IGF1 mRNA CTD PMID:15034205 , PMID:16960034 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10765 6480464 Tetrachlorodibenzodioxin results in decreased expression of IGF1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of IGF1 protein CTD PMID:19770486 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10765 6480464 Tetrachlorodibenzodioxin affects the expression of IGF1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of IGF1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IGF1 mRNA CTD PMID:16960034 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased phosphorylation of and results in decreased activity of EIF4EBP1 protein] more ... CTD PMID:15746889 , PMID:23639626 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of IGF1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of IGF1 protein CTD PMID:15703265 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases activity ISO RGD:10765 6480464 Tetrachlorodibenzodioxin results in decreased activity of IGF1 protein CTD PMID:20486776 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:10765 6480464 6-diphenylmethyl-5-(5-isopropyl-2-methoxybenzylamino)-1-azabicyclo(2.2.2)octane-3-carboxylic acid inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein] more ... CTD PMID:18200517 , PMID:20889569 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein CTD PMID:24782617 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:10765 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA, Trinitrobenzenesulfonic Acid results in increased expression of IGF1 protein CTD PMID:18200517 , PMID:20889569 2,4-dibromophenyl 2,4,5-tribromophenyl ether multiple interactions EXP 6480464 2 more ... CTD PMID:16414171 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression EXP 6480464 2 more ... CTD PMID:16414171 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of IGF1 mRNA CTD PMID:21346803 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione affects expression ISO RGD:70506 6480464 Thalidomide affects the expression of IGF1 mRNA CTD PMID:15939924 2-nitrotoluene increases expression EXP 6480464 2-nitrotoluene results in increased expression of IGF1 mRNA CTD PMID:16460773 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:19327374 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:10765 6480464 3 more ... CTD PMID:30312631 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:10765 6480464 3 more ... CTD PMID:30312631 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:19692669 , PMID:23196670 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:10765 6480464 tetrabromobisphenol A results in decreased expression of IGF1 mRNA CTD PMID:25172293 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of IGF1 mRNA CTD PMID:28300664 3,3',5,5'-tetrabromobisphenol A affects expression EXP 6480464 tetrabromobisphenol A affects the expression of IGF1 mRNA CTD PMID:26988606 3,3',5-triiodo-L-thyronine multiple interactions EXP 6480464 Estradiol inhibits the reaction [Triiodothyronine results in increased expression of IGF1 mRNA], Estradiol inhibits the reaction [Triiodothyronine results in increased secretion of IGF1 protein] CTD PMID:7684602 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of IGF1 mRNA CTD PMID:7684602 3,3',5-triiodo-L-thyronine increases secretion EXP 6480464 Triiodothyronine results in increased secretion of IGF1 protein CTD PMID:7684602 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of IGF1 mRNA CTD PMID:28522335 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:10765 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of IGF1 mRNA CTD PMID:16054899 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:70506 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of IGF1 mRNA CTD PMID:28628672 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of IGF1 mRNA CTD PMID:19162173 4-hydroxynon-2-enal increases expression ISO RGD:10765 6480464 4-hydroxy-2-nonenal results in increased expression of IGF1 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide decreases activity ISO RGD:70506 6480464 Fenretinide results in decreased activity of IGF1 protein CTD PMID:15735044 4-hydroxyphenyl retinamide decreases expression ISO RGD:10765 6480464 Fenretinide results in decreased expression of IGF1 mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide multiple interactions ISO RGD:70506 6480464 Fenretinide inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:25246272 4-tert-Octylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of IGF1 mRNA CTD PMID:17011747 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of IGF1 mRNA CTD PMID:16888818 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of IGF1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of IGF1 mRNA CTD PMID:19483382 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of IGF1 mRNA CTD PMID:24780913 7,12-dimethyltetraphene multiple interactions ISO RGD:10765 6480464 IGF1 protein results in increased susceptibility to [9 more ... CTD PMID:10365914 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:70506 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGF1 mRNA CTD PMID:20147733 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of IGF1 mRNA CTD PMID:15749267 actinomycin D decreases response to substance ISO RGD:10765 6480464 IGF1 protein results in decreased susceptibility to Dactinomycin CTD PMID:9525472 afimoxifene increases expression ISO RGD:10765 6480464 afimoxifene results in increased expression of IGF1 mRNA CTD PMID:10965916 aflatoxin B1 affects expression ISO RGD:70506 6480464 Aflatoxin B1 affects the expression of IGF1 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO RGD:70506 6480464 Aflatoxin B1 results in decreased methylation of IGF1 gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:70506 6480464 Aflatoxin B1 results in decreased expression of IGF1 mRNA CTD PMID:27153756 aflatoxin B1 affects expression ISO RGD:10765 6480464 Aflatoxin B1 affects the expression of IGF1 mRNA CTD PMID:19770486 AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [[IGF1 protein co-treated with FSHB protein] results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:16020477 aldehydo-D-glucose increases uptake ISO RGD:70506 6480464 IGF1 protein results in increased uptake of Glucose CTD PMID:29330302 all-trans-4-oxoretinoic acid increases expression ISO RGD:70506 6480464 4-oxoretinoic acid results in increased expression of IGF1 mRNA CTD PMID:15982314 all-trans-retinoic acid multiple interactions ISO RGD:70506 6480464 Tretinoin inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein], Tretinoin inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein] CTD PMID:16565789 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [Lipopolysaccharides results in increased expression of IGF1 mRNA], Tretinoin inhibits the reaction [Lipopolysaccharides results in increased expression of IGF1 protein] CTD PMID:16448778 all-trans-retinoic acid increases expression ISO RGD:70506 6480464 Tretinoin metabolite results in increased expression of IGF1 mRNA, Tretinoin results in increased expression of IGF1 mRNA CTD PMID:15982314 alpha-(methylamino)isobutyric acid increases uptake EXP 6480464 IGF1 protein results in increased uptake of 2-(methylamino)isobutyric acid CTD PMID:1928324 alpha-(methylamino)isobutyric acid multiple interactions EXP 6480464 oxophenylarsine inhibits the reaction [IGF1 protein results in increased uptake of 2-(methylamino)isobutyric acid] CTD PMID:1928324 aluminium atom multiple interactions ISO RGD:70506 6480464 Aluminum inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 aluminium oxide affects expression ISO RGD:70506 6480464 Aluminum Oxide affects the expression of IGF1 mRNA CTD PMID:19464052 aluminium sulfate (anhydrous) increases secretion ISO RGD:70506 6480464 aluminum sulfate results in increased secretion of IGF1 protein CTD PMID:7685579 aluminium(0) multiple interactions ISO RGD:70506 6480464 Aluminum inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 aluminium(3+) multiple interactions ISO RGD:70506 6480464 Aluminum inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 amino acid multiple interactions ISO RGD:10765 6480464 Amino Acids inhibits the reaction [KL gene mutant form results in decreased expression of IGF1 mRNA], H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in decreased expression of IGF1 mRNA]] CTD PMID:25309793 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of IGF1 mRNA CTD PMID:19483382 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of IGF1 mRNA CTD PMID:16483693 anandamide increases expression ISO RGD:10765 6480464 anandamide results in increased expression of IGF1 protein CTD PMID:17307377 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:70506 6480464 pyrazolanthrone inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein], pyrazolanthrone inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein] CTD PMID:17458902 arsane multiple interactions ISO RGD:10765 6480464 [[Arsenic results in decreased expression of IGF1 mRNA] co-treated with [Arsenic affects the localization of and results in increased expression of EZH2 protein]] results in decreased expression of MYOG CTD PMID:22426358 arsane affects methylation ISO RGD:70506 6480464 Arsenic affects the methylation of IGF1 gene CTD PMID:25304211 arsenic atom multiple interactions ISO RGD:10765 6480464 [[Arsenic results in decreased expression of IGF1 mRNA] co-treated with [Arsenic affects the localization of and results in increased expression of EZH2 protein]] results in decreased expression of MYOG CTD PMID:22426358 arsenic atom affects methylation ISO RGD:70506 6480464 Arsenic affects the methylation of IGF1 gene CTD PMID:25304211 arsenic(3+) affects methylation ISO RGD:70506 6480464 Arsenic affects the methylation of IGF1 gene CTD PMID:25304211 arsenic(3+) multiple interactions ISO RGD:10765 6480464 [[Arsenic results in decreased expression of IGF1 mRNA] co-treated with [Arsenic affects the localization of and results in increased expression of EZH2 protein]] results in decreased expression of MYOG CTD PMID:22426358 arsenite(3-) multiple interactions ISO RGD:10765 6480464 [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of IGF1 mRNA CTD PMID:15894712 arsenite(3-) decreases expression ISO RGD:10765 6480464 arsenite results in decreased expression of IGF1 mRNA CTD PMID:15894712 , PMID:18191166 astemizole multiple interactions ISO RGD:70506 6480464 Astemizole inhibits the reaction [IGF1 protein results in increased activity of KCNH1 protein] CTD PMID:17520698 azathioprine multiple interactions ISO RGD:70506 6480464 Azathioprine inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] more ... CTD PMID:23958494 baicalein multiple interactions ISO RGD:70506 6480464 baicalein inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein] CTD PMID:17458902 belinostat increases expression ISO RGD:70506 6480464 belinostat results in increased expression of IGF1 mRNA CTD PMID:23671600 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of IGF1 mRNA CTD PMID:19483382 benzo[a]pyrene increases expression ISO RGD:70506 6480464 Benzo(a)pyrene results in increased expression of IGF1 mRNA CTD PMID:17879257 benzo[a]pyrene decreases expression ISO RGD:10765 6480464 Benzo(a)pyrene results in decreased expression of IGF1 mRNA CTD PMID:15034205 more ... benzo[a]pyrene increases expression ISO RGD:10765 6480464 Benzo(a)pyrene results in increased expression of IGF1 mRNA CTD PMID:15894712 , PMID:22610609 benzo[a]pyrene multiple interactions ISO RGD:70506 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 , PMID:30726812 benzo[a]pyrene multiple interactions ISO RGD:10765 6480464 [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of IGF1 mRNA, AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of IGF1 mRNA] CTD PMID:15034205 , PMID:15894712 benzo[a]pyrene affects expression ISO RGD:10765 6480464 Benzo(a)pyrene affects the expression of IGF1 mRNA CTD PMID:15037607 benzo[b]fluoranthene multiple interactions ISO RGD:70506 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of IGF1 mRNA CTD PMID:17690111 benzo[b]fluoranthene increases expression ISO RGD:70506 6480464 benzo(b)fluoranthene results in increased expression of IGF1 mRNA CTD PMID:16269432 Benzoyl peroxide multiple interactions ISO RGD:10765 6480464 IGF1 protein results in increased susceptibility to [9 more ... CTD PMID:10365914 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IGF1 mRNA CTD PMID:18164116 bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of IGF1 protein CTD PMID:15591091 bezafibrate decreases expression ISO RGD:70506 6480464 Bezafibrate results in decreased expression of IGF1 protein CTD PMID:10716467 bicalutamide multiple interactions ISO RGD:70506 6480464 [bicalutamide co-treated with Tamoxifen] results in decreased expression of IGF1 protein, bicalutamide inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1 mRNA] CTD PMID:16368782 , PMID:16847815 bicalutamide increases expression ISO RGD:70506 6480464 bicalutamide results in increased expression of IGF1 mRNA, bicalutamide results in increased expression of IGF1 protein CTD PMID:16368782 , PMID:16847815 bis(2-chloroethyl) sulfide decreases expression ISO RGD:10765 6480464 Mustard Gas results in decreased expression of IGF1 mRNA CTD PMID:15674843 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:10765 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of IGF1 mRNA] CTD PMID:19850644 bis(2-ethylhexyl) phthalate increases expression ISO RGD:10765 6480464 Diethylhexyl Phthalate results in increased expression of IGF1 mRNA CTD PMID:31211961 bis(2-ethylhexyl) phthalate increases expression ISO RGD:70506 6480464 Diethylhexyl Phthalate results in increased expression of IGF1 mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of IGF1 mRNA CTD PMID:22610992 , PMID:26472102 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:10765 6480464 Diethylhexyl Phthalate results in decreased expression of IGF1 mRNA CTD PMID:19850644 , PMID:29753845 bisphenol A affects expression ISO RGD:70506 6480464 bisphenol A affects the expression of IGF1 mRNA CTD PMID:21826169 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of IGF1 gene CTD PMID:28505145 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of IGF1 mRNA CTD PMID:25181051 , PMID:27103539 bisphenol A decreases expression ISO RGD:70506 6480464 bisphenol A results in decreased expression of IGF1 mRNA, bisphenol A results in decreased expression of IGF1 protein CTD PMID:27271280 , PMID:27685785 bisphenol A increases expression ISO RGD:70506 6480464 bisphenol A results in increased expression of IGF1 mRNA CTD PMID:18007998 more ... bisphenol A decreases expression ISO RGD:10765 6480464 bisphenol A results in decreased expression of IGF1 mRNA CTD PMID:26063408 bisphenol A increases expression ISO RGD:10765 6480464 bisphenol A results in increased expression of IGF1 mRNA CTD PMID:10965916 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IGF1 mRNA, bisphenol A results in increased expression of IGF1 protein CTD PMID:12075121 , PMID:22842222 bisphenol A multiple interactions ISO RGD:10765 6480464 bisphenol A affects the reaction [CYP19A1 affects the expression of IGF1 mRNA] CTD PMID:11985600 bisphenol A multiple interactions ISO RGD:70506 6480464 [bisphenol A results in decreased expression of MIR27B] which results in increased expression of IGF1 mRNA more ... CTD PMID:20064783 more ... bosentan affects expression ISO RGD:70506 6480464 Bosentan affects the expression of IGF1 mRNA CTD PMID:29761207 bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of IGF1 mRNA CTD PMID:12628495 bromochloroacetic acid increases expression EXP 6480464 bromochloroacetic acid results in increased expression of IGF1 mRNA CTD PMID:16460773 bucladesine multiple interactions ISO RGD:70506 6480464 Bucladesine promotes the reaction [IGF1 protein results in increased abundance of Estradiol] more ... CTD PMID:22798350 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of IGF1 mRNA CTD PMID:24136188 Butylbenzyl phthalate decreases expression EXP 6480464 butylbenzyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of IGF1 mRNA CTD PMID:19167457 cadmium atom decreases expression ISO RGD:10765 6480464 Cadmium results in decreased expression of IGF1 mRNA CTD PMID:22666406 cadmium atom multiple interactions ISO RGD:10765 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1 mRNA CTD PMID:29373603 cadmium atom multiple interactions ISO RGD:70506 6480464 Cadmium promotes the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 cadmium dichloride increases expression ISO RGD:70506 6480464 Cadmium Chloride results in increased expression of IGF1 protein CTD PMID:26138014 cadmium dichloride multiple interactions ISO RGD:10765 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of IGF1 mRNA CTD PMID:29373603 cadmium dichloride multiple interactions ISO RGD:70506 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGF1 protein] CTD PMID:26138014 caffeine decreases secretion ISO RGD:10765 6480464 Caffeine results in decreased secretion of IGF1 protein CTD PMID:1995187 caffeine affects expression EXP 6480464 Caffeine affects the expression of IGF1 protein CTD PMID:29343424 caffeine decreases activity EXP 6480464 Caffeine results in decreased activity of IGF1 protein CTD PMID:24239806 caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of IGF1 mRNA, Caffeine results in decreased expression of IGF1 protein CTD PMID:22583948 more ... calcidiol increases expression EXP 6480464 Calcifediol deficiency results in increased expression of IGF1 mRNA CTD PMID:17293106 calcitriol affects expression ISO RGD:70506 6480464 Calcitriol affects the expression of IGF1 mRNA CTD PMID:19918113 calcium atom affects expression EXP 6480464 Calcium affects the expression of IGF1 mRNA CTD PMID:15913539 calcium atom multiple interactions ISO RGD:10765 6480464 Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium], tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224 more ... calcium atom increases import ISO RGD:10765 6480464 IGF1 protein results in increased import of Calcium CTD PMID:1550224 more ... calcium(0) affects expression EXP 6480464 Calcium affects the expression of IGF1 mRNA CTD PMID:15913539 calcium(0) multiple interactions ISO RGD:10765 6480464 Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium], tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224 more ... calcium(0) increases import ISO RGD:10765 6480464 IGF1 protein results in increased import of Calcium CTD PMID:1550224 more ... Candesartan cilexetil multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 mRNA], candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 protein] CTD PMID:10547078 capsaicin increases expression ISO RGD:70506 6480464 Capsaicin results in increased expression of IGF1 mRNA, Capsaicin results in increased expression of IGF1 protein CTD PMID:21310942 capsaicin increases expression ISO RGD:10765 6480464 Capsaicin results in increased expression of IGF1 mRNA, Capsaicin results in increased expression of IGF1 protein CTD PMID:17307377 more ... capsaicin multiple interactions EXP 6480464 capsazepine inhibits the reaction [Capsaicin results in increased expression of IGF1 protein] CTD PMID:17693108 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of IGF1 protein CTD PMID:17693108 capsaicin multiple interactions ISO RGD:10765 6480464 CALCA protein affects the reaction [Capsaicin results in increased expression of IGF1 mRNA] more ... CTD PMID:17360009 , PMID:17569567 capsaicin multiple interactions ISO RGD:70506 6480464 [Capsaicin co-treated with Isoflavones] results in increased expression of IGF1 protein, TRPV1 affects the reaction [Capsaicin results in increased expression of IGF1 mRNA] CTD PMID:19502719 , PMID:21310942 capsazepine multiple interactions EXP 6480464 capsazepine inhibits the reaction [Capsaicin results in increased expression of IGF1 protein] CTD PMID:17693108 capsiate increases expression ISO RGD:10765 6480464 capsiate results in increased expression of IGF1 protein CTD PMID:17307377 carbamazepine decreases expression EXP 6480464 Carbamazepine results in decreased expression of IGF1 mRNA CTD PMID:17381134 carbon nanotube affects expression ISO RGD:10765 6480464 Nanotubes, Carbon affects the expression of IGF1 mRNA CTD PMID:23845593 , PMID:25620056 carbon nanotube increases expression ISO RGD:10765 6480464 Nanotubes, Carbon analog results in increased expression of IGF1 mRNA, Nanotubes, Carbon results in increased expression of IGF1 mRNA CTD PMID:25554681 more ... carmustine decreases expression ISO RGD:70506 6480464 Carmustine results in decreased expression of IGF1 protein CTD PMID:18443378 carmustine increases expression ISO RGD:70506 6480464 Carmustine results in increased expression of IGF1 protein CTD PMID:15286697 cetrorelix decreases expression ISO RGD:70506 6480464 cetrorelix results in decreased expression of IGF1 mRNA CTD PMID:21062912 chelerythrine affects activity EXP 6480464 chelerythrine affects the activity of IGF1 protein CTD PMID:11548882 chlormequat affects expression EXP 6480464 Chlormequat affects the expression of IGF1 protein CTD PMID:28214531 chlormequat chloride affects expression EXP 6480464 Chlormequat affects the expression of IGF1 protein CTD PMID:28214531 chloroprene decreases expression ISO RGD:10765 6480464 Chloroprene results in decreased expression of IGF1 mRNA CTD PMID:23125180 chlorpyrifos decreases expression ISO RGD:10765 6480464 Chlorpyrifos results in decreased expression of IGF1 mRNA CTD PMID:20350560 cholesterol multiple interactions EXP 6480464 [1, 2-dioleoyloxy-3-(trimethylammonium)propane co-treated with Cholesterol] results in increased expression of IGF1 protein CTD PMID:16034455 chromium atom decreases expression EXP 6480464 Chromium deficiency results in decreased expression of IGF1 protein CTD PMID:9868179 chromium(3+) decreases expression EXP 6480464 Chromium deficiency results in decreased expression of IGF1 protein CTD PMID:9868179 chromium(3+) trichloride increases expression ISO RGD:10765 6480464 chromic chloride results in increased expression of IGF1 mRNA CTD PMID:12153762 chromium(3+) trichloride multiple interactions EXP 6480464 chromic chloride promotes the reaction [INS1 protein results in increased expression of IGF1 mRNA] CTD PMID:20013160 chrysin multiple interactions EXP 6480464 chrysin inhibits the reaction [Testosterone results in increased expression of IGF1 mRNA] CTD PMID:29247772 ciguatoxin CTX1B affects expression ISO RGD:10765 6480464 Ciguatoxins affects the expression of IGF1 mRNA CTD PMID:18353800 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of IGF1 mRNA CTD PMID:19483382 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of IGF1 mRNA CTD PMID:12851107 clofibrate decreases expression ISO RGD:10765 6480464 Clofibrate results in decreased expression of IGF1 mRNA CTD PMID:17585979 clofibrate multiple interactions ISO RGD:10765 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of IGF1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IGF1 mRNA] CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of IGF1 mRNA CTD PMID:17602206 clozapine decreases expression ISO RGD:70506 6480464 Clozapine results in decreased expression of IGF1 protein CTD PMID:11769361 cobalt atom multiple interactions ISO RGD:10765 6480464 Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224 more ... cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of IGF1 mRNA CTD PMID:23694759 cobalt dichloride multiple interactions ISO RGD:70506 6480464 [cobaltous chloride co-treated with IGF1 protein] results in increased secretion of VEGFA protein more ... CTD PMID:16499871 cobalt(2+) multiple interactions ISO RGD:10765 6480464 Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224 more ... cobalt(2+) sulfate increases secretion EXP 6480464 cobalt sulfate results in increased secretion of IGF1 protein CTD PMID:25310813 Colforsin dapropate hydrochloride multiple interactions ISO RGD:70506 6480464 Colforsin promotes the reaction [IGF1 protein results in increased abundance of Estradiol] more ... CTD PMID:22798350 copper atom multiple interactions ISO RGD:70506 6480464 Copper affects the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 copper atom multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Copper] CTD PMID:15745444 copper atom decreases expression EXP 6480464 Copper deficiency results in decreased expression of IGF1 protein CTD PMID:15734878 copper atom decreases activity ISO RGD:70506 6480464 Copper deficiency results in decreased activity of IGF1 protein CTD PMID:17339407 copper(0) multiple interactions ISO RGD:70506 6480464 Copper affects the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 copper(0) multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Copper] CTD PMID:15745444 copper(0) decreases expression EXP 6480464 Copper deficiency results in decreased expression of IGF1 protein CTD PMID:15734878 copper(0) decreases activity ISO RGD:70506 6480464 Copper deficiency results in decreased activity of IGF1 protein CTD PMID:17339407 copper(2+) decreases expression EXP 6480464 Copper deficiency results in decreased expression of IGF1 protein CTD PMID:15734878 copper(2+) multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Copper] CTD PMID:15745444 copper(2+) decreases activity ISO RGD:70506 6480464 Copper deficiency results in decreased activity of IGF1 protein CTD PMID:17339407 copper(2+) multiple interactions ISO RGD:70506 6480464 Copper affects the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 copper(II) chloride increases expression ISO RGD:10765 6480464 cupric chloride results in increased expression of IGF1 mRNA CTD PMID:17211630 corticosterone decreases expression EXP 6480464 Corticosterone results in decreased expression of IGF1 mRNA, Corticosterone results in decreased expression of IGF1 protein CTD PMID:12807724 more ... corticosterone multiple interactions EXP 6480464 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3 more ... CTD PMID:29343424 corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of IGF1 mRNA CTD PMID:15755911 cortisol multiple interactions ISO RGD:70506 6480464 IGF1 protein inhibits the reaction [Hydrocortisone results in decreased expression of APOB mRNA] more ... CTD PMID:30528684 , PMID:31075344 cortisol decreases expression ISO RGD:70506 6480464 Hydrocortisone results in decreased expression of IGF1 mRNA, Hydrocortisone results in decreased expression of IGF1 protein CTD PMID:30528684 , PMID:31075344 crocidolite asbestos affects expression ISO RGD:70506 6480464 Asbestos, Crocidolite affects the expression of IGF1 mRNA CTD PMID:17331233 curcumin multiple interactions ISO RGD:70506 6480464 Curcumin inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein], Curcumin inhibits the reaction [IGF1 protein results in increased activity of IGF1R protein] CTD PMID:17458902 , PMID:17499312 curcumin decreases expression ISO RGD:70506 6480464 Curcumin analog results in decreased expression of IGF1 mRNA CTD PMID:26409325 curcumin multiple interactions ISO RGD:10765 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IGF1 mRNA] CTD PMID:18200517 curcumin decreases secretion ISO RGD:70506 6480464 Curcumin results in decreased secretion of IGF1 protein CTD PMID:17499312 curcumin decreases activity ISO RGD:70506 6480464 Curcumin results in decreased activity of IGF1 protein CTD PMID:17499312 cycloheximide multiple interactions ISO RGD:10765 6480464 Cycloheximide inhibits the reaction [IGF1 protein affects the metabolism of 1, 2-diacylglycerol] CTD PMID:2120207 cycloheximide multiple interactions ISO RGD:70506 6480464 IGF1 protein inhibits the reaction [Cycloheximide results in decreased expression of CDKN1A protein] CTD PMID:26687534 cyclosporin A multiple interactions ISO RGD:70506 6480464 Cyclosporine inhibits the reaction [IGF1 protein results in increased activity of HIF1A protein], Cyclosporine inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein] CTD PMID:16682453 cyclosporin A decreases expression ISO RGD:10765 6480464 Cyclosporine results in decreased expression of IGF1 mRNA CTD PMID:19770486 cyclosporin A increases secretion ISO RGD:70506 6480464 Cyclosporine results in increased secretion of IGF1 protein CTD PMID:16882103 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [IGF1 protein results in increased expression of NPPA mRNA] CTD PMID:11548882 cyclosporin A affects activity EXP 6480464 Cyclosporine affects the activity of IGF1 protein CTD PMID:11548882 cyclosporin A decreases expression ISO RGD:70506 6480464 Cyclosporine results in decreased expression of IGF1 mRNA CTD PMID:20106945 , PMID:27989131 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of IGF1 mRNA CTD PMID:22528246 cyproconazole decreases expression ISO RGD:10765 6480464 cyproconazole results in decreased expression of IGF1 mRNA CTD PMID:22334560 cyproterone acetate multiple interactions ISO RGD:70506 6480464 [Ethinyl Estradiol co-treated with Cyproterone Acetate] results in decreased expression of IGF1 protein CTD PMID:16002536 D-glucose increases uptake ISO RGD:70506 6480464 IGF1 protein results in increased uptake of Glucose CTD PMID:29330302 D-mannitol multiple interactions ISO RGD:70506 6480464 IGF1 inhibits the reaction [Mannitol results in increased activity of CASP3 protein] CTD PMID:10567913 D-penicillamine multiple interactions ISO RGD:70506 6480464 Penicillamine inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 dantrolene decreases response to substance ISO RGD:70506 6480464 Dantrolene results in decreased susceptibility to IGF1 protein CTD PMID:16485066 DDE multiple interactions ISO RGD:70506 6480464 Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of IGF1 mRNA] CTD PMID:25682698 DDT multiple interactions ISO RGD:70506 6480464 DDT affects the reaction [Metribolone results in increased expression of IGF1 mRNA] CTD PMID:25682698 DDT increases methylation ISO RGD:70506 6480464 DDT results in increased methylation of IGF1 gene CTD PMID:30822522 Deguelin multiple interactions ISO RGD:70506 6480464 deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein], deguelin inhibits the reaction [IGF1 protein results in increased expression of VEGFA mRNA] CTD PMID:17764071 Deoxycorticosterone acetate multiple interactions EXP 6480464 [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of IGF1 mRNA CTD PMID:22228705 deoxynivalenol multiple interactions ISO RGD:10765 6480464 deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGF1 mRNA] CTD PMID:19805407 deoxynivalenol decreases expression ISO RGD:10765 6480464 deoxynivalenol results in decreased expression of IGF1 protein CTD PMID:19805407 dexamethasone multiple interactions ISO RGD:70506 6480464 [Dexamethasone co-treated with Sirolimus] inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:15070696 , PMID:28628672 dexamethasone decreases expression ISO RGD:10765 6480464 Dexamethasone results in decreased expression of IGF1 mRNA CTD PMID:22733784 dexamethasone increases expression ISO RGD:10765 6480464 Dexamethasone results in increased expression of IGF1 mRNA CTD PMID:23935943 , PMID:30878453 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of IGF1 mRNA CTD PMID:14618091 , PMID:19853640 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF1 mRNA], Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF1 protein] CTD PMID:10370016 dexamethasone multiple interactions ISO RGD:10765 6480464 [Dexamethasone co-treated with IGF1 protein] results in decreased expression of CKM protein more ... CTD PMID:16054899 more ... dexamethasone decreases expression ISO RGD:70506 6480464 Dexamethasone results in decreased expression of IGF1 mRNA CTD PMID:19681914 dextran sulfate multiple interactions ISO RGD:10765 6480464 [Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IGF1 protein CTD PMID:19931517 diazinon affects expression EXP 6480464 Diazinon affects the expression of IGF1 mRNA CTD PMID:22546817 dibenz[a,h]anthracene increases expression ISO RGD:70506 6480464 1 more ... CTD PMID:16269432 dibenz[a,h]anthracene multiple interactions ISO RGD:70506 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:17690111 dibenziodolium multiple interactions ISO RGD:70506 6480464 diphenyleneiodonium inhibits the reaction [IGF1 protein results in increased expression of ZNF143 protein] CTD PMID:20733350 dibenzo[a,l]pyrene multiple interactions ISO RGD:70506 6480464 [Benzo(a)pyrene co-treated with dibenzo(a, l)pyrene] affects the expression of IGF1 mRNA CTD PMID:17690111 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of IGF1 mRNA CTD PMID:15829613 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of IGF1 mRNA CTD PMID:21266533 , PMID:26472102 dicoumarol multiple interactions ISO RGD:70506 6480464 Dicumarol inhibits the reaction [IGF1 protein results in increased phosphorylation of JUN protein] CTD PMID:11278392 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of IGF1 mRNA CTD PMID:22546817 dienogest multiple interactions ISO RGD:70506 6480464 [Ethinyl Estradiol co-treated with dienogest] results in decreased expression of IGF1 protein CTD PMID:11172797 diethyl malate affects expression ISO RGD:10765 6480464 diethyl malate affects the expression of IGF1 mRNA CTD PMID:24814887 diethyl phthalate decreases expression EXP 6480464 diethyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 diethylstilbestrol increases expression ISO RGD:10765 6480464 Diethylstilbestrol results in increased expression of IGF1 mRNA CTD PMID:10965916 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of IGF1 mRNA CTD PMID:17011747 , PMID:27103539 dihydrocapsaicin increases expression ISO RGD:10765 6480464 dihydrocapsaicin results in increased expression of IGF1 protein CTD PMID:17307377 Dimethyl phthalate decreases expression EXP 6480464 dimethyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 dioxygen affects methylation ISO RGD:10765 6480464 Oxygen deficiency affects the methylation of IGF1 promoter CTD PMID:24205000 dioxygen increases expression ISO RGD:70506 6480464 [Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of IGF1 mRNA CTD PMID:26305601 dioxygen increases expression EXP 6480464 Oxygen results in increased expression of IGF1 mRNA CTD PMID:22911455 dioxygen decreases expression ISO RGD:10765 6480464 Oxygen deficiency results in decreased expression of IGF1 mRNA CTD PMID:24205000 dipentyl phthalate decreases expression EXP 6480464 di-n-pentyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 disodium selenite multiple interactions ISO RGD:10765 6480464 [ptaquiloside co-treated with Sodium Selenite] results in decreased expression of IGF1 mRNA CTD PMID:23274088 disodium selenite decreases expression ISO RGD:10765 6480464 Sodium Selenite results in decreased expression of IGF1 mRNA CTD PMID:23274088 diuron decreases expression EXP 6480464 Diuron results in decreased expression of IGF1 mRNA CTD PMID:25152437 dobutamine increases response to substance EXP 6480464 IGF1 protein results in increased susceptibility to Dobutamine CTD PMID:17184500 doxorubicin multiple interactions ISO RGD:70506 6480464 Doxorubicin promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]] CTD PMID:16740780 doxorubicin decreases expression ISO RGD:70506 6480464 Doxorubicin results in decreased expression of IGF1 mRNA CTD PMID:29803840 doxorubicin decreases response to substance ISO RGD:10765 6480464 IGF1 protein results in decreased susceptibility to Doxorubicin CTD PMID:9525472 doxorubicin decreases expression ISO RGD:10765 6480464 Doxorubicin results in decreased expression of IGF1 mRNA CTD PMID:25896364 doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of IGF1 protein CTD PMID:8792405 enalapril affects expression EXP 6480464 Enalapril affects the expression of IGF1 protein CTD PMID:12883983 enalapril decreases expression EXP 6480464 Enalapril results in decreased expression of IGF1 mRNA CTD PMID:12883983 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of IGF1 mRNA CTD PMID:29391264 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of IGF1 mRNA CTD PMID:28559116 epoxiconazole decreases expression ISO RGD:10765 6480464 epoxiconazole results in decreased expression of IGF1 mRNA CTD PMID:22334560 estriol increases expression ISO RGD:70506 6480464 Estriol results in increased expression of IGF1 mRNA CTD PMID:15969240 ethanol multiple interactions ISO RGD:70506 6480464 [Ethanol co-treated with sodium arsenite] results in increased expression of IGF1 mRNA more ... CTD PMID:14745455 more ... ethanol multiple interactions ISO RGD:10765 6480464 Ethanol results in decreased expression of and results in decreased secretion of IGF1 protein CTD PMID:29524503 ethanol decreases expression ISO RGD:70506 6480464 Ethanol results in decreased expression of IGF1 mRNA, Ethanol results in decreased expression of IGF1 protein CTD PMID:31226463 ethanol affects expression EXP 6480464 Ethanol affects the expression of IGF1 mRNA, Ethanol affects the expression of IGF1 protein CTD PMID:31039417 , PMID:31075344 ethanol affects secretion EXP 6480464 Ethanol affects the secretion of IGF1 protein CTD PMID:26188107 ethanol increases expression EXP 6480464 Ethanol results in increased expression of IGF1 mRNA, Ethanol results in increased expression of IGF1 protein CTD PMID:15353170 , PMID:24275070 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of IGF1 mRNA, Ethanol results in decreased expression of IGF1 protein CTD PMID:24275070 more ... ethanol multiple interactions EXP 6480464 [Dietary Fats co-treated with Ethanol] results in increased expression of IGF1 mRNA more ... CTD PMID:12700235 , PMID:24275070 ethylene glycol bis(2-aminoethyl)tetraacetic acid decreases response to substance ISO RGD:70506 6480464 Egtazic Acid results in decreased susceptibility to IGF1 protein CTD PMID:16485066 felbamate decreases expression EXP 6480464 felbamate results in decreased expression of IGF1 mRNA CTD PMID:17381134 fenarimol decreases expression EXP 6480464 fenarimol results in decreased expression of IGF1 mRNA CTD PMID:15590119 fenvalerate decreases expression ISO RGD:10765 6480464 fenvalerate results in decreased expression of IGF1 mRNA CTD PMID:22210404 fenvalerate decreases secretion ISO RGD:10765 6480464 fenvalerate results in decreased secretion of IGF1 protein CTD PMID:22210404 fipronil decreases expression ISO RGD:70506 6480464 fipronil results in decreased expression of IGF1 mRNA CTD PMID:27091632 fipronil multiple interactions ISO RGD:70506 6480464 [fipronil co-treated with DEET] results in decreased expression of IGF1 mRNA CTD PMID:27091632 flavonoids decreases expression ISO RGD:70506 6480464 Flavonoids results in decreased expression of IGF1 mRNA, Flavonoids results in decreased expression of IGF1 protein CTD PMID:15922007 flavonol multiple interactions ISO RGD:70506 6480464 3-hydroxyflavone inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein] more ... CTD PMID:17458902 fluoranthene multiple interactions ISO RGD:70506 6480464 [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of IGF1 mRNA CTD PMID:17690111 flutamide multiple interactions ISO RGD:70506 6480464 Flutamide inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1 mRNA] CTD PMID:16368782 flutamide increases expression EXP 6480464 Flutamide results in increased expression of IGF1 mRNA CTD PMID:24793618 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of IGF1 mRNA CTD PMID:24136188 fluvastatin multiple interactions ISO RGD:70506 6480464 [zoledronic acid co-treated with fluvastatin] results in increased expression of IGF1 mRNA CTD PMID:16996129 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [naringin results in increased expression of IGF1 mRNA] CTD PMID:23596885 fumonisin B1 decreases expression ISO RGD:10765 6480464 fumonisin B1 results in decreased expression of IGF1 mRNA CTD PMID:16221962 furan decreases expression EXP 6480464 furan results in decreased expression of IGF1 mRNA CTD PMID:15120968 more ... furazolidone multiple interactions ISO RGD:70506 6480464 IGF1 protein inhibits the reaction [Furazolidone results in decreased phosphorylation of AKT1 protein] CTD PMID:26687534 furosemide increases expression EXP 6480464 Furosemide results in increased expression of IGF1 mRNA CTD PMID:16526316 gabapentin increases expression EXP 6480464 gabapentin results in increased expression of IGF1 mRNA CTD PMID:17381134 gadolinium trichloride multiple interactions EXP 6480464 gadolinium chloride inhibits the reaction [Lipopolysaccharides results in decreased expression of IGF1 protein] CTD PMID:16522730 gamma-hexachlorocyclohexane decreases expression EXP 6480464 Hexachlorocyclohexane results in decreased expression of IGF1 mRNA CTD PMID:17785943 genistein decreases expression ISO RGD:10765 6480464 Genistein results in decreased expression of IGF1 mRNA CTD PMID:11880592 genistein decreases expression ISO RGD:70506 6480464 Genistein results in decreased expression of IGF1 mRNA CTD PMID:20706672 genistein decreases expression EXP 6480464 Genistein results in decreased expression of IGF1 mRNA CTD PMID:20381596 genistein increases expression EXP 6480464 Genistein results in increased expression of IGF1 mRNA CTD PMID:12075121 genistein affects activity EXP 6480464 Genistein affects the activity of IGF1 protein CTD PMID:11548882 genistein increases expression ISO RGD:10765 6480464 Genistein results in increased expression of IGF1 mRNA CTD PMID:10965916 ginsenoside Rb1 multiple interactions EXP 6480464 ginsenoside Rb1 inhibits the reaction [aluminum chloride results in decreased expression of IGF1 mRNA] CTD PMID:27470910 ginsenoside Rb1 increases expression EXP 6480464 ginsenoside Rb1 results in increased expression of IGF1 mRNA CTD PMID:27470910 glucose increases uptake ISO RGD:70506 6480464 IGF1 protein results in increased uptake of Glucose CTD PMID:29330302 glutathione multiple interactions ISO RGD:10765 6480464 deoxynivalenol promotes the reaction [Glutathione results in increased expression of IGF1 mRNA] CTD PMID:19805407 glutathione increases expression ISO RGD:10765 6480464 Glutathione results in increased expression of IGF1 mRNA CTD PMID:19805407 gold atom multiple interactions ISO RGD:70506 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 gold(0) multiple interactions ISO RGD:70506 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 gold(1+) multiple interactions ISO RGD:70506 6480464 Gold inhibits the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 griseofulvin decreases expression ISO RGD:10765 6480464 Griseofulvin results in decreased expression of IGF1 mRNA CTD PMID:12735108 heptachlor decreases expression EXP 6480464 Heptachlor results in decreased expression of IGF1 mRNA CTD PMID:23153324 hexachlorobenzene affects expression ISO RGD:10765 6480464 Hexachlorobenzene affects the expression of IGF1 mRNA CTD PMID:28923513 hexachlorobenzene multiple interactions ISO RGD:10765 6480464 Hexachlorobenzene affects the reaction [AHR protein affects the expression of IGF1 mRNA] CTD PMID:28923513 hydrogen peroxide decreases abundance ISO RGD:70506 6480464 IGF1 protein results in decreased abundance of Hydrogen Peroxide CTD PMID:22843358 hydrogen peroxide decreases expression ISO RGD:70506 6480464 Hydrogen Peroxide results in decreased expression of IGF1 mRNA CTD PMID:26339600 hydroquinone multiple interactions ISO RGD:70506 6480464 IGF1 protein inhibits the reaction [hydroquinone results in decreased expression of CTNNB1 protein] more ... CTD PMID:28886972 ibuprofen increases expression EXP 6480464 Ibuprofen results in increased expression of IGF1 protein CTD PMID:16799050 icariin increases expression EXP 6480464 icariin results in increased expression of IGF1 mRNA CTD PMID:18236786 indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of IGF1 mRNA CTD PMID:23142791 indometacin multiple interactions ISO RGD:70506 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of IGF1 mRNA CTD PMID:28628672 irinotecan increases expression ISO RGD:70506 6480464 Irinotecan metabolite results in increased expression of IGF1 mRNA, Irinotecan results in increased expression of IGF1 mRNA CTD PMID:15956246 iron atom multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Iron] CTD PMID:15745444 iron(0) multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Iron] CTD PMID:15745444 isoflavones multiple interactions ISO RGD:70506 6480464 [Capsaicin co-treated with Isoflavones] results in increased expression of IGF1 protein CTD PMID:19502719 isoflavones affects expression EXP 6480464 Isoflavones affects the expression of IGF1 mRNA CTD PMID:18522411 isoflavones multiple interactions ISO RGD:10765 6480464 Isoflavones promotes the reaction [Capsaicin results in increased expression of IGF1 protein] CTD PMID:17569567 isoflurane multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:25597859 isoflurane decreases expression EXP 6480464 Isoflurane results in decreased expression of IGF1 protein CTD PMID:25597859 isoprenaline decreases expression ISO RGD:10765 6480464 Isoproterenol results in decreased expression of IGF1 mRNA CTD PMID:20003209 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of IGF1 mRNA, Isoproterenol results in increased expression of IGF1 protein CTD PMID:10547078 isoprenaline multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 mRNA], candesartan cilexetil inhibits the reaction [Isoproterenol results in increased expression of IGF1 protein] CTD PMID:10547078 isotretinoin increases expression ISO RGD:70506 6480464 Isotretinoin results in increased expression of IGF1 mRNA CTD PMID:15982314 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of IGF1 mRNA CTD PMID:19483382 L-methionine decreases expression ISO RGD:10765 6480464 Methionine deficiency results in decreased expression of IGF1 protein CTD PMID:15924568 lead diacetate decreases expression ISO RGD:10765 6480464 lead acetate results in decreased expression of IGF1 protein CTD PMID:24200854 lead diacetate increases methylation EXP 6480464 lead acetate results in increased methylation of IGF1 gene CTD PMID:29571894 lead(0) multiple interactions ISO RGD:70506 6480464 Lead inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 lead(0) decreases expression ISO RGD:70506 6480464 Lead results in decreased expression of IGF1 protein CTD PMID:23632160 lead(2+) multiple interactions ISO RGD:70506 6480464 Lead inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 lead(2+) decreases expression ISO RGD:70506 6480464 Lead results in decreased expression of IGF1 protein CTD PMID:23632160 leflunomide increases expression ISO RGD:10765 6480464 leflunomide results in increased expression of IGF1 mRNA CTD PMID:19751817 leuprolide multiple interactions ISO RGD:70506 6480464 Leuprolide inhibits the reaction [IGF1 protein results in increased expression of and affects the localization of [ITGA5 protein binds to ITGB3 protein]], Leuprolide inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] CTD PMID:17143537 levonorgestrel multiple interactions ISO RGD:70506 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of IGF1 protein CTD PMID:11172797 linuron increases expression EXP 6480464 Linuron results in increased expression of IGF1 mRNA CTD PMID:12730624 lipopolysaccharide multiple interactions ISO RGD:70506 6480464 [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IGF1 protein CTD PMID:18437699 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IGF1 mRNA, Lipopolysaccharides results in increased expression of IGF1 protein CTD PMID:16448778 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of IGF1 protein CTD PMID:16522730 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Rutin] results in decreased expression of IGF1 mRNA more ... CTD PMID:16448778 more ... lipopolysaccharide multiple interactions ISO RGD:10765 6480464 [IGF1 protein co-treated with Lipopolysaccharides] results in decreased expression of TLR4 mRNA more ... CTD PMID:21371294 lithium chloride multiple interactions ISO RGD:10765 6480464 Lithium Chloride promotes the reaction [IGF1 protein results in increased expression of MYH4 mRNA] CTD PMID:19657059 lornoxicam decreases expression EXP 6480464 lornoxicam results in decreased expression of IGF1 mRNA CTD PMID:23142791 lovastatin decreases response to substance ISO RGD:10765 6480464 IGF1 protein results in decreased susceptibility to Lovastatin CTD PMID:9525472 LY294002 multiple interactions ISO RGD:70506 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ascorbate-2-phosphate results in increased secretion of IGF1 protein] more ... CTD PMID:12569580 more ... LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] more ... CTD PMID:18388193 more ... LY294002 increases expression ISO RGD:70506 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of ascorbate-2-phosphate results in increased expression of IGF1 mRNA CTD PMID:19416266 LY294002 multiple interactions ISO RGD:10765 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein results in increased expression of MYH4 mRNA], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased secretion of IGF1 protein]] CTD PMID:19657059 , PMID:26254549 lycopene multiple interactions ISO RGD:70506 6480464 lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein] more ... CTD PMID:16565789 lycopene decreases expression EXP 6480464 lycopene results in decreased expression of IGF1 mRNA CTD PMID:15084515 lycopene increases expression ISO RGD:70506 6480464 lycopene results in increased expression of IGF1 mRNA CTD PMID:16886892 lycopene decreases expression ISO RGD:70506 6480464 lycopene results in decreased expression of IGF1 mRNA CTD PMID:16886892 maleic acid increases expression ISO RGD:70506 6480464 maleic acid results in increased expression of IGF1 mRNA CTD PMID:28392987 maneb multiple interactions ISO RGD:10765 6480464 [Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA more ... CTD PMID:23963992 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of IGF1 mRNA CTD PMID:21402727 masoprocol multiple interactions ISO RGD:70506 6480464 Masoprocol inhibits the reaction [IGF1 protein promotes the reaction [IGF1R protein results in increased phosphorylation of and results in increased activity of IGF1R protein]] more ... CTD PMID:18491370 , PMID:18645000 melatonin multiple interactions ISO RGD:10765 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA] CTD PMID:23963992 mercury atom multiple interactions ISO RGD:70506 6480464 Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of IGF1 mRNA CTD PMID:7540432 , PMID:8538927 mercury(0) multiple interactions ISO RGD:70506 6480464 Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 mercury(2+) multiple interactions ISO RGD:70506 6480464 Mercury inhibits the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 metformin multiple interactions ISO RGD:70506 6480464 [Metformin co-treated with IGF1 protein] results in decreased expression of IGF1R mRNA more ... CTD PMID:21664031 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Testosterone results in increased expression of IGF1 mRNA] CTD PMID:26492952 metformin multiple interactions ISO RGD:10765 6480464 Metformin inhibits the reaction [IL13 protein results in increased expression of IGF1 mRNA], Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein] CTD PMID:23927877 , PMID:26497364 methimazole multiple interactions ISO RGD:70506 6480464 [IGF1 protein co-treated with Methimazole] results in decreased phosphorylation of MAPK1 protein more ... CTD PMID:29990518 methimazole decreases expression ISO RGD:70506 6480464 Methimazole results in decreased expression of IGF1 mRNA, Methimazole results in decreased expression of IGF1 protein CTD PMID:29990518 methimazole decreases expression ISO RGD:10765 6480464 Methimazole results in decreased expression of IGF1 mRNA, Methimazole results in decreased expression of IGF1 protein CTD PMID:29990518 methoxychlor decreases expression ISO RGD:10765 6480464 Methoxychlor metabolite results in decreased expression of IGF1 mRNA CTD PMID:11509743 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of IGF1 mRNA CTD PMID:27103539 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of IGF1 gene CTD PMID:23303685 methoxychlor decreases expression EXP 6480464 Methoxychlor results in decreased expression of IGF1 mRNA CTD PMID:21782745 methoxychlor multiple interactions ISO RGD:10765 6480464 [Estradiol co-treated with Methoxychlor metabolite] results in decreased expression of IGF1 mRNA CTD PMID:11509743 methyl methanesulfonate decreases expression ISO RGD:70506 6480464 Methyl Methanesulfonate results in decreased expression of IGF1 mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO RGD:10765 6480464 methylmercuric chloride results in decreased expression of IGF1 mRNA CTD PMID:19465457 methylseleninic acid increases expression ISO RGD:70506 6480464 methylselenic acid results in increased expression of IGF1 mRNA CTD PMID:11830524 mifepristone multiple interactions ISO RGD:70506 6480464 Mifepristone inhibits the reaction [[Estradiol co-treated with Progesterone] results in increased secretion of IGF1 protein] more ... CTD PMID:15809018 , PMID:30528684 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of IGF1 mRNA CTD PMID:25972201 MK-2206 multiple interactions EXP 6480464 MK 2206 inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]] CTD PMID:25597859 monodansylcadaverine multiple interactions ISO RGD:70506 6480464 monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein], monodansylcadaverine inhibits the reaction [IGF1 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:20733350 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP 6480464 N more ... CTD PMID:14644152 N,N-diethyl-m-toluamide multiple interactions ISO RGD:70506 6480464 [fipronil co-treated with DEET] results in decreased expression of IGF1 mRNA CTD PMID:27091632 N-acetyl-L-cysteine multiple interactions ISO RGD:70506 6480464 Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein] more ... CTD PMID:17458902 , PMID:26138014 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:70506 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [IGF1 protein promotes the reaction [1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:15888489 , PMID:20064577 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:10765 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased secretion of IGF1 protein more ... CTD PMID:26254549 N-methyl-4-phenylpyridinium decreases expression ISO RGD:10765 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of IGF1 mRNA, 1-Methyl-4-phenylpyridinium results in decreased expression of IGF1 protein CTD PMID:26254549 , PMID:28268219 N-methyl-4-phenylpyridinium decreases response to substance ISO RGD:70506 6480464 IGF1 protein results in decreased susceptibility to 1-Methyl-4-phenylpyridinium CTD PMID:20064577 N-methyl-N-nitrosourea increases response to substance ISO RGD:70506 6480464 IGF1 protein results in increased susceptibility to Methylnitrosourea CTD PMID:15528971 N-nitrosodiethylamine increases expression ISO RGD:10765 6480464 Diethylnitrosamine results in increased expression of IGF1 mRNA CTD PMID:17942915 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of IGF1 mRNA CTD PMID:19638242 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IGF1 mRNA more ... CTD PMID:17602206 more ... N-nitrosodiethylamine multiple interactions ISO RGD:10765 6480464 MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of IGF1 mRNA] CTD PMID:17942915 N-nitrosodiethylamine affects expression EXP 6480464 Diethylnitrosamine affects the expression of IGF1 mRNA CTD PMID:20387270 naphthalene increases expression ISO RGD:10765 6480464 naphthalene results in increased expression of IGF1 mRNA CTD PMID:18978301 naringin affects expression EXP 6480464 naringin affects the expression of IGF1 mRNA CTD PMID:24880026 naringin multiple interactions ISO RGD:10765 6480464 naringin inhibits the reaction [Dexamethasone results in increased expression of IGF1 mRNA] CTD PMID:30878453 naringin increases expression EXP 6480464 naringin results in increased expression of IGF1 mRNA CTD PMID:23596885 naringin multiple interactions EXP 6480464 fulvestrant inhibits the reaction [naringin results in increased expression of IGF1 mRNA] CTD PMID:23596885 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of IGF1 mRNA CTD PMID:24136188 nickel atom decreases response to substance ISO RGD:70506 6480464 Nickel results in decreased susceptibility to IGF1 protein CTD PMID:16485066 nickel atom decreases expression ISO RGD:70506 6480464 Nickel results in decreased expression of IGF1 mRNA CTD PMID:24768652 , PMID:25583101 nickel dichloride multiple interactions ISO RGD:70506 6480464 [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of IGF1 protein CTD PMID:18437699 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of IGF1 mRNA, Nicotine results in decreased expression of IGF1 protein CTD PMID:20960268 , PMID:22265867 nicotine increases expression EXP 6480464 Nicotine results in increased expression of IGF1 mRNA CTD PMID:29486207 nicotine multiple interactions EXP 6480464 rosiglitazone inhibits the reaction [Nicotine results in decreased expression of IGF1 protein] CTD PMID:20960268 nifedipine decreases response to substance ISO RGD:70506 6480464 Nifedipine results in decreased susceptibility to IGF1 protein CTD PMID:16485066 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of IGF1 mRNA CTD PMID:23142791 , PMID:24136188 nitrofen multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF1 mRNA], Dexamethasone inhibits the reaction [nitrofen results in increased expression of IGF1 protein] CTD PMID:10370016 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of IGF1 mRNA, nitrofen results in increased expression of IGF1 protein CTD PMID:10370016 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of IGF1 mRNA CTD PMID:11409163 nitroprusside decreases response to substance ISO RGD:70506 6480464 IGF1 protein results in decreased susceptibility to Nitroprusside CTD PMID:10203697 nitroprusside multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Nitroprusside results in decreased expression of BCL2 protein], IGF1 protein inhibits the reaction [Nitroprusside results in increased expression of BAX protein] CTD PMID:10203697 nonivamide increases expression ISO RGD:10765 6480464 nonivamide results in increased expression of IGF1 protein CTD PMID:17307377 ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of IGF1 mRNA CTD PMID:16251485 octreotide affects expression ISO RGD:70506 6480464 Octreotide affects the expression of IGF1 protein CTD PMID:16449332 , PMID:2111918 octreotide decreases expression ISO RGD:70506 6480464 Octreotide results in decreased expression of IGF1 protein CTD PMID:10806600 more ... okadaic acid multiple interactions ISO RGD:10765 6480464 IGF1 protein results in increased susceptibility to [9 more ... CTD PMID:10365914 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of IGF1 mRNA CTD PMID:19483382 Osajin decreases expression ISO RGD:70506 6480464 osajin results in decreased expression of IGF1 mRNA CTD PMID:20706672 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] affects the expression of IGF1 mRNA CTD PMID:25729387 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of IGF1 mRNA CTD PMID:25729387 p-menthan-3-ol decreases expression ISO RGD:70506 6480464 Menthol results in decreased expression of IGF1 mRNA CTD PMID:26760959 para-Cresidine increases response to substance ISO RGD:10765 6480464 IGF1 protein results in increased susceptibility to cresidine CTD PMID:19415693 paracetamol increases expression ISO RGD:10765 6480464 Acetaminophen results in increased expression of IGF1 mRNA CTD PMID:17585979 paracetamol decreases expression ISO RGD:70506 6480464 Acetaminophen results in decreased expression of IGF1 mRNA CTD PMID:26497421 , PMID:27761495 paracetamol multiple interactions ISO RGD:10765 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of IGF1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IGF1 mRNA] CTD PMID:17585979 paraquat multiple interactions ISO RGD:10765 6480464 [Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA more ... CTD PMID:17979500 , PMID:23963992 paraquat increases expression ISO RGD:10765 6480464 Paraquat results in increased expression of IGF1 protein CTD PMID:23898955 paraquat increases expression EXP 6480464 Paraquat results in increased expression of IGF1 mRNA CTD PMID:20498031 pendimethalin decreases expression EXP 6480464 pendimethalin results in decreased expression of IGF1 mRNA CTD PMID:19897005 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of IGF1 mRNA CTD PMID:25710175 pentetic acid multiple interactions EXP 6480464 Pentetic Acid inhibits the reaction [Zinc Sulfate results in decreased expression of IGF1 mRNA] CTD PMID:9685221 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of IGF1 mRNA CTD PMID:19397962 perfluorooctanoic acid increases expression ISO RGD:10765 6480464 perfluorooctanoic acid results in increased expression of IGF1 mRNA, perfluorooctanoic acid results in increased expression of IGF1 protein CTD PMID:18467677 , PMID:20118188 perfluorooctanoic acid decreases expression ISO RGD:70506 6480464 perfluorooctanoic acid results in decreased expression of IGF1 mRNA CTD PMID:25868421 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of IGF1 mRNA CTD PMID:19162173 phenacetin decreases expression EXP 6480464 Phenacetin results in decreased expression of IGF1 mRNA CTD PMID:23142791 phenobarbital multiple interactions ISO RGD:10765 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of IGF1 mRNA] CTD PMID:19482888 phenobarbital affects expression ISO RGD:10765 6480464 Phenobarbital affects the expression of IGF1 mRNA CTD PMID:23091169 phenobarbital affects expression ISO RGD:70506 6480464 Phenobarbital affects the expression of IGF1 mRNA CTD PMID:19159669 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of IGF1 mRNA CTD PMID:12082028 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of IGF1 mRNA CTD PMID:17381134 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of IGF1 mRNA CTD PMID:19162173 phenobarbital decreases expression ISO RGD:10765 6480464 Phenobarbital results in decreased expression of IGF1 mRNA CTD PMID:19482888 phenylarsine oxide multiple interactions EXP 6480464 oxophenylarsine inhibits the reaction [IGF1 protein results in increased uptake of 2-(methylamino)isobutyric acid] CTD PMID:1928324 phenylarsine oxide decreases localization EXP 6480464 oxophenylarsine results in decreased localization of IGF1 protein CTD PMID:9145794 phenylephrine affects response to substance EXP 6480464 IGF1 protein affects the susceptibility to Phenylephrine CTD PMID:11159833 phenytoin decreases expression EXP 6480464 Phenytoin results in decreased expression of IGF1 mRNA CTD PMID:17381134 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10765 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IGF1 mRNA more ... CTD PMID:10365914 , PMID:16368122 phosphatidylcholine increases degradation ISO RGD:10765 6480464 IGF1 protein results in increased degradation of Phosphatidylcholines CTD PMID:2120207 picolinic acid multiple interactions EXP 6480464 picolinic acid promotes the reaction [INS1 protein results in increased expression of IGF1 mRNA] CTD PMID:20013160 picropodophyllotoxin multiple interactions ISO RGD:10765 6480464 [picropodophyllin co-treated with IGF1 protein] results in increased expression of TNF mRNA more ... CTD PMID:21371294 pirinixic acid multiple interactions ISO RGD:10765 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of IGF1 mRNA, PPARA protein affects the reaction [pirinixic acid results in decreased expression of IGF1 mRNA] CTD PMID:16221962 , PMID:20813756 pirinixic acid decreases expression ISO RGD:10765 6480464 pirinixic acid results in decreased expression of IGF1 mRNA CTD PMID:12727805 more ... pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of IGF1 mRNA CTD PMID:19483382 Polaprezinc increases expression ISO RGD:70506 6480464 polaprezinc results in increased expression of IGF1 mRNA CTD PMID:10423164 poly(I:C) multiple interactions ISO RGD:10765 6480464 IL6 protein affects the reaction [Poly I-C results in decreased expression of IGF1 protein] CTD PMID:21195166 poly(I:C) decreases expression ISO RGD:10765 6480464 Poly I-C results in decreased expression of IGF1 protein CTD PMID:21195166 Pomiferin decreases expression ISO RGD:70506 6480464 pomiferin results in decreased expression of IGF1 mRNA CTD PMID:20706672 potassium atom affects transport EXP 6480464 IGF1 protein affects the transport of Potassium CTD PMID:18388193 potassium chloride increases response to substance EXP 6480464 IGF1 protein results in increased susceptibility to Potassium Chloride CTD PMID:11159833 potassium chloride multiple interactions EXP 6480464 [Desoxycorticosterone Acetate co-treated with Sodium Chloride, Dietary co-treated with Potassium Chloride] results in decreased expression of IGF1 mRNA CTD PMID:22228705 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of IGF1 mRNA CTD PMID:30315952 prazosin multiple interactions EXP 6480464 Prazosin inhibits the reaction [IGF1 protein results in decreased susceptibility to Norepinephrine] CTD PMID:17184500 prednisolone decreases response to substance ISO RGD:70506 6480464 Prednisolone results in decreased susceptibility to IGF1 protein CTD PMID:16079165 prednisolone increases expression ISO RGD:70506 6480464 Prednisolone results in increased expression of IGF1 protein CTD PMID:16079165 pregnenolone multiple interactions ISO RGD:70506 6480464 [FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone, FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of IGF1 mRNA CTD PMID:19162173 prochloraz decreases expression EXP 6480464 prochloraz results in decreased expression of IGF1 mRNA CTD PMID:16375936 progesterone multiple interactions ISO RGD:70506 6480464 [Estradiol co-treated with Progesterone] results in increased secretion of IGF1 protein more ... CTD PMID:15809018 more ... progesterone increases expression EXP 6480464 Progesterone results in increased expression of IGF1 mRNA CTD PMID:19853640 more ... progesterone increases abundance ISO RGD:70506 6480464 IGF1 protein results in increased abundance of Progesterone CTD PMID:19081562 more ... progesterone increases abundance EXP 6480464 IGF1 protein results in increased abundance of Progesterone CTD PMID:21239528 progesterone multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [BMP15 protein inhibits the reaction [FSHB protein results in increased abundance of Progesterone]] more ... CTD PMID:21239528 , PMID:22067323 progesterone increases expression ISO RGD:70506 6480464 Progesterone results in increased expression of IGF1 mRNA CTD PMID:20864642 progesterone increases expression ISO RGD:10765 6480464 Progesterone results in increased expression of IGF1 mRNA CTD PMID:8390853 progesterone multiple interactions ISO RGD:10765 6480464 [Estradiol co-treated with Progesterone] promotes the reaction [Cuprizone results in increased expression of IGF1 mRNA] more ... CTD PMID:18562952 more ... progesterone affects expression ISO RGD:10765 6480464 Progesterone affects the expression of IGF1 mRNA CTD PMID:17251523 progesterone increases secretion ISO RGD:70506 6480464 Progesterone results in increased secretion of IGF1 protein CTD PMID:15809018 propiconazole decreases expression ISO RGD:10765 6480464 propiconazole results in decreased expression of IGF1 mRNA CTD PMID:21278054 , PMID:22334560 Ptaquiloside multiple interactions ISO RGD:10765 6480464 [ptaquiloside co-treated with Sodium Selenite] results in decreased expression of IGF1 mRNA CTD PMID:23274088 Ptaquiloside decreases expression ISO RGD:10765 6480464 ptaquiloside results in decreased expression of IGF1 mRNA CTD PMID:23274088 puerarin decreases expression ISO RGD:70506 6480464 puerarin results in decreased expression of IGF1 mRNA CTD PMID:20706672 puerarin multiple interactions ISO RGD:10765 6480464 puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein] CTD PMID:23927877 quercetin multiple interactions ISO RGD:70506 6480464 Quercetin inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein] CTD PMID:17458902 quercetin multiple interactions ISO RGD:10765 6480464 Quercetin inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein] more ... CTD PMID:24353828 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of IGF1 mRNA CTD PMID:24943009 quercetin decreases expression ISO RGD:70506 6480464 Quercetin results in decreased expression of IGF1 mRNA CTD PMID:20658310 quinidine multiple interactions ISO RGD:70506 6480464 Quinidine inhibits the reaction [IGF1 protein results in increased activity of KCNH1 protein] CTD PMID:17520698 raloxifene decreases expression ISO RGD:70506 6480464 Raloxifene Hydrochloride results in decreased expression of IGF1 mRNA, Raloxifene Hydrochloride results in decreased expression of IGF1 protein CTD PMID:15978972 more ... raloxifene increases expression ISO RGD:70506 6480464 Raloxifene Hydrochloride results in increased expression of IGF1 mRNA CTD PMID:15762036 , PMID:17872375 raloxifene multiple interactions ISO RGD:70506 6480464 Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter] more ... CTD PMID:17872375 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of IGF1 mRNA CTD PMID:19350480 reactive oxygen species multiple interactions ISO RGD:70506 6480464 [IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein more ... CTD PMID:20733350 reactive oxygen species increases abundance ISO RGD:70506 6480464 IGF1 protein results in increased abundance of Reactive Oxygen Species CTD PMID:20733350 Rebamipide increases expression EXP 6480464 rebamipide results in increased expression of IGF1 mRNA CTD PMID:15104358 resveratrol decreases response to substance ISO RGD:70506 6480464 resveratrol results in decreased susceptibility to IGF1 protein CTD PMID:15297429 resveratrol decreases response to substance ISO RGD:10765 6480464 resveratrol results in decreased susceptibility to IGF1 protein CTD PMID:24782617 resveratrol multiple interactions ISO RGD:10765 6480464 resveratrol inhibits the reaction [IGF1 protein binds to and results in increased phosphorylation of and results in increased activity of IGF1R protein], resveratrol inhibits the reaction [IGF1 protein results in increased expression of COL1A2 mRNA] CTD PMID:24782617 resveratrol decreases expression ISO RGD:10765 6480464 resveratrol results in decreased expression of IGF1 mRNA, resveratrol results in decreased expression of IGF1 protein CTD PMID:17086191 more ... resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of IGF1 mRNA CTD PMID:19228061 resveratrol decreases expression ISO RGD:70506 6480464 resveratrol results in decreased expression of IGF1 mRNA CTD PMID:20706672 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of IGF1 mRNA CTD PMID:23848300 resveratrol increases expression ISO RGD:70506 6480464 resveratrol results in increased expression of IGF1 mRNA CTD PMID:12002526 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Dihydrotestosterone results in increased secretion of IGF1 protein] more ... CTD PMID:16626303 more ... resveratrol multiple interactions ISO RGD:70506 6480464 resveratrol inhibits the reaction [IGF1 protein binds to and results in increased phosphorylation of and results in increased activity of IGF1R protein] more ... CTD PMID:15297429 more ... Rosavin decreases expression ISO RGD:70506 6480464 rosavin results in decreased expression of IGF1 mRNA CTD PMID:20706672 rotenone multiple interactions ISO RGD:70506 6480464 Rotenone inhibits the reaction [IGF1 protein results in increased activity of ODC1 protein] CTD PMID:9834970 ruthenium red multiple interactions ISO RGD:70506 6480464 Ruthenium Red inhibits the reaction [IGF1 protein results in increased secretion of VEGFA protein] CTD PMID:20539001 rutin multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Rutin] results in decreased expression of IGF1 mRNA CTD PMID:28693884 SB 203580 multiple interactions ISO RGD:10765 6480464 SB 203580 inhibits the reaction [TGFB1 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased secretion of IGF1 protein]] CTD PMID:26254549 shikimic acid increases expression ISO RGD:10765 6480464 Shikimic Acid results in increased expression of IGF1 mRNA CTD PMID:15265014 silicon dioxide decreases expression ISO RGD:10765 6480464 Silicon Dioxide results in decreased expression of IGF1 mRNA CTD PMID:19073995 silicon dioxide increases expression ISO RGD:10765 6480464 Silicon Dioxide results in increased expression of IGF1 mRNA CTD PMID:30453980 silver atom decreases expression ISO RGD:10765 6480464 Silver results in decreased expression of IGF1 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:10765 6480464 Silver results in decreased expression of IGF1 mRNA CTD PMID:27131904 silver(1+) decreases expression ISO RGD:10765 6480464 Silver results in decreased expression of IGF1 mRNA CTD PMID:27131904 simvastatin multiple interactions ISO RGD:10765 6480464 [Simvastatin co-treated with NVP-AEW541] inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] more ... CTD PMID:17327694 , PMID:27734117 sirolimus multiple interactions ISO RGD:70506 6480464 [Dexamethasone co-treated with Sirolimus] inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6KB1 protein] more ... CTD PMID:15070696 more ... sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [[IGF1 protein co-treated with U 0126] promotes the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]] more ... CTD PMID:19105244 , PMID:25597859 sirolimus increases response to substance ISO RGD:70506 6480464 Sirolimus results in increased susceptibility to IGF1 protein CTD PMID:16227402 sirolimus multiple interactions ISO RGD:10765 6480464 Sirolimus inhibits the reaction [IL2 protein results in increased expression of IGF1 mRNA] CTD PMID:11355896 sodium arsenate increases expression ISO RGD:10765 6480464 sodium arsenate results in increased expression of IGF1 mRNA CTD PMID:21795629 sodium arsenite multiple interactions ISO RGD:70506 6480464 [Ethanol co-treated with sodium arsenite] results in increased expression of IGF1 mRNA more ... CTD PMID:18182400 , PMID:19349368 sodium arsenite decreases expression ISO RGD:70506 6480464 sodium arsenite results in decreased expression of IGF1 mRNA CTD PMID:29301061 sodium arsenite increases expression ISO RGD:10765 6480464 sodium arsenite results in increased expression of IGF1 mRNA CTD PMID:17077188 sodium arsenite decreases expression ISO RGD:10765 6480464 sodium arsenite results in decreased expression of IGF1 mRNA, sodium arsenite results in decreased expression of IGF1 protein CTD PMID:15276417 more ... sodium arsenite increases expression ISO RGD:70506 6480464 sodium arsenite results in increased expression of IGF1 mRNA CTD PMID:19349368 sodium arsenite multiple interactions ISO RGD:10765 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IGF1 mRNA CTD PMID:16368122 sodium arsenite affects expression ISO RGD:10765 6480464 sodium arsenite affects the expression of IGF1 mRNA CTD PMID:16507464 sodium atom multiple interactions EXP 6480464 [GH1 protein co-treated with IGF1 protein] affects the transport of Sodium, IGF1 protein affects the transport of [Sodium co-treated with Chlorides] CTD PMID:18388193 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of IGF1 mRNA CTD PMID:22561333 sodium fluoride decreases expression ISO RGD:10765 6480464 Sodium Fluoride results in decreased expression of IGF1 protein CTD PMID:21461751 Sodium salicylate multiple interactions ISO RGD:10765 6480464 Sodium Salicylate promotes the reaction [[EGF protein co-treated with IGF1 protein] results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:10993886 sorafenib multiple interactions ISO RGD:70506 6480464 sorafenib inhibits the reaction [IGF1 protein results in increased expression of BIRC5 protein] CTD PMID:21601561 sphingosine 1-phosphate increases expression ISO RGD:70506 6480464 sphingosine 1-phosphate results in increased expression of IGF1 mRNA CTD PMID:19349368 staurosporine multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Staurosporine results in increased activity of CASP3 protein], IGF1 protein inhibits the reaction [Staurosporine results in increased activity of CASP7 protein] CTD PMID:19406941 staurosporine affects activity EXP 6480464 Staurosporine affects the activity of IGF1 protein CTD PMID:11548882 streptozocin multiple interactions ISO RGD:10765 6480464 IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein] more ... CTD PMID:11375343 , PMID:23927877 streptozocin decreases expression ISO RGD:10765 6480464 Streptozocin results in decreased expression of IGF1 protein CTD PMID:23927877 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of IGF1 protein CTD PMID:9868179 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of IGF1 mRNA, Streptozocin results in decreased expression of IGF1 protein CTD PMID:25617479 , PMID:7637645 succimer multiple interactions ISO RGD:10765 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of IGF1 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of IGF1 mRNA CTD PMID:21641980 , PMID:26378955 superoxide decreases abundance ISO RGD:70506 6480464 IGF1 protein results in decreased abundance of Superoxides CTD PMID:22843358 tacrolimus hydrate increases response to substance EXP 6480464 IGF1 protein results in increased susceptibility to Tacrolimus CTD PMID:12826230 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of IGF1 mRNA CTD PMID:19400957 tamoxifen increases expression ISO RGD:10765 6480464 Tamoxifen results in increased expression of IGF1 mRNA CTD PMID:19400957 tamoxifen affects expression ISO RGD:10765 6480464 Tamoxifen affects the expression of IGF1 mRNA CTD PMID:17555576 tamoxifen decreases expression ISO RGD:70506 6480464 Tamoxifen results in decreased expression of IGF1 protein CTD PMID:20332317 tamoxifen multiple interactions ISO RGD:70506 6480464 [bicalutamide co-treated with Tamoxifen] results in decreased expression of IGF1 protein more ... CTD PMID:15809018 , PMID:16847815 tauroursodeoxycholic acid decreases expression EXP 6480464 tauroursodeoxycholic acid results in decreased expression of IGF1 mRNA CTD PMID:15885361 tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of IGF1 mRNA CTD PMID:22659508 testosterone increases expression ISO RGD:70506 6480464 Testosterone results in increased expression of IGF1 mRNA, Testosterone results in increased expression of IGF1 protein CTD PMID:16002536 , PMID:16368782 testosterone multiple interactions EXP 6480464 chrysin inhibits the reaction [Testosterone results in increased expression of IGF1 mRNA], Metformin inhibits the reaction [Testosterone results in increased expression of IGF1 mRNA] CTD PMID:26492952 , PMID:29247772 testosterone increases expression EXP 6480464 Testosterone results in increased expression of IGF1 mRNA, Testosterone results in increased expression of IGF1 protein CTD PMID:10100480 more ... testosterone decreases expression ISO RGD:10765 6480464 Testosterone deficiency results in decreased expression of IGF1 mRNA, Testosterone results in decreased expression of IGF1 mRNA CTD PMID:21045173 , PMID:22138414 testosterone multiple interactions ISO RGD:10765 6480464 Testosterone inhibits the reaction [Testosterone deficiency results in decreased expression of IGF1 mRNA] CTD PMID:21045173 testosterone affects expression ISO RGD:10765 6480464 Testosterone affects the expression of IGF1 mRNA CTD PMID:20403060 testosterone increases secretion ISO RGD:70506 6480464 Testosterone results in increased secretion of IGF1 protein CTD PMID:16368782 testosterone enanthate decreases expression EXP 6480464 testosterone enanthate results in decreased expression of IGF1 mRNA CTD PMID:23085480 tetrachloromethane affects expression ISO RGD:10765 6480464 Carbon Tetrachloride affects the expression of IGF1 mRNA CTD PMID:17484886 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of IGF1 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions EXP 6480464 IGF1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Copper] more ... CTD PMID:12800242 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of IGF1 mRNA, Carbon Tetrachloride results in increased expression of IGF1 protein CTD PMID:12800242 , PMID:15070850 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of IGF1 mRNA CTD PMID:16239168 tetradecane decreases expression EXP 6480464 n-tetradecane results in decreased expression of IGF1 protein CTD PMID:17337753 tetramethrin multiple interactions ISO RGD:10765 6480464 tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium] CTD PMID:1550224 more ... tetrathiomolybdate(2-) multiple interactions ISO RGD:70506 6480464 [tetrathiomolybdate results in decreased activity of SOD1 protein] inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:18480265 thalidomide affects expression ISO RGD:70506 6480464 Thalidomide affects the expression of IGF1 mRNA CTD PMID:15939924 thimerosal multiple interactions ISO RGD:70506 6480464 Thimerosal affects the reaction [IGF1 protein results in increased activity of MTR protein] CTD PMID:14745455 thimerosal multiple interactions ISO RGD:10765 6480464 IGF1 protein inhibits the reaction [Thimerosal results in decreased expression of BIRC5 protein] more ... CTD PMID:23145070 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of IGF1 mRNA CTD PMID:19483382 thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of IGF1 mRNA CTD PMID:28943392 thymidine decreases uptake ISO RGD:70506 6480464 IGF1 protein results in decreased uptake of Thymidine CTD PMID:1332906 thymidine multiple interactions ISO RGD:70506 6480464 [Tetrachlorodibenzodioxin co-treated with Estradiol] inhibits the reaction [IGF1 protein results in increased uptake of Thymidine], Tetrachlorodibenzodioxin inhibits the reaction [IGF1 protein results in decreased uptake of Thymidine] CTD PMID:1332906 thyroxine increases expression ISO RGD:10765 6480464 Thyroxine results in increased expression of IGF1 mRNA CTD PMID:23935926 Tiron multiple interactions ISO RGD:70506 6480464 1 more ... CTD PMID:17458902 titanium dioxide decreases expression ISO RGD:10765 6480464 titanium dioxide results in decreased expression of IGF1 mRNA, titanium dioxide results in decreased expression of IGF1 protein CTD PMID:23565150 topiramate decreases expression EXP 6480464 topiramate results in decreased expression of IGF1 mRNA CTD PMID:16979414 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] affects the expression of IGF1 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of IGF1 mRNA CTD PMID:25729387 trichostatin A increases expression ISO RGD:10765 6480464 trichostatin A results in increased expression of IGF1 mRNA CTD PMID:23463510 triclosan increases expression EXP 6480464 Triclosan results in increased expression of IGF1 mRNA CTD PMID:30447264 trilostane multiple interactions ISO RGD:70506 6480464 [FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone, FGF9 protein inhibits the reaction [[FSHB protein co-treated with IGF1 protein co-treated with trilostane] results in increased abundance of Pregnenolone] CTD PMID:22798350 trimethyltin increases expression ISO RGD:10765 6480464 trimethyltin results in increased expression of IGF1 mRNA CTD PMID:21435392 troglitazone increases expression ISO RGD:10765 6480464 troglitazone results in increased expression of IGF1 CTD PMID:21937740 tunicamycin multiple interactions ISO RGD:70506 6480464 Tunicamycin inhibits the reaction [IGF1 protein results in increased N-linked glycosylation of IGFBP3 protein] CTD PMID:15277511 undecane increases expression EXP 6480464 undecane results in increased expression of IGF1 protein CTD PMID:17337753 urethane multiple interactions ISO RGD:10765 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of IGF1 mRNA more ... CTD PMID:12400877 , PMID:12810352 valproic acid affects expression ISO RGD:10765 6480464 Valproic Acid affects the expression of IGF1 mRNA CTD PMID:17963808 valproic acid increases expression ISO RGD:10765 6480464 Valproic Acid results in increased expression of IGF1 mRNA CTD PMID:24896083 valproic acid affects expression ISO RGD:70506 6480464 Valproic Acid affects the expression of IGF1 mRNA CTD PMID:25979313 valproic acid decreases methylation ISO RGD:70506 6480464 Valproic Acid results in decreased methylation of IGF1 gene CTD PMID:29154799 valproic acid decreases expression ISO RGD:70506 6480464 Valproic Acid results in decreased expression of IGF1 mRNA CTD PMID:23179753 , PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of IGF1 mRNA CTD PMID:17381134 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of IGF1 mRNA CTD PMID:19015723 vincristine decreases response to substance ISO RGD:10765 6480464 IGF1 protein results in decreased susceptibility to Vincristine CTD PMID:9452187 vincristine multiple interactions ISO RGD:70506 6480464 Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]] CTD PMID:16740780 wortmannin multiple interactions ISO RGD:70506 6480464 [wortmannin co-treated with U 0126] inhibits the reaction [IGF1 protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]] more ... CTD PMID:12569580 more ... wortmannin multiple interactions ISO RGD:10765 6480464 wortmannin inhibits the reaction [IGF1 protein results in increased expression of MYH4 mRNA] CTD PMID:19657059 zearalenone decreases expression ISO RGD:70506 6480464 Zearalenone results in decreased expression of IGF1 mRNA CTD PMID:28965971 zearalenone increases expression ISO RGD:70506 6480464 Zearalenone results in increased expression of IGF1 mRNA CTD PMID:27757495 zinc atom increases import ISO RGD:10765 6480464 IGF1 protein results in increased import of Zinc CTD PMID:16443356 zinc atom multiple interactions ISO RGD:70506 6480464 Zinc promotes the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 zinc atom multiple interactions ISO RGD:10765 6480464 [Zinc binds to calcium silicate] which results in increased expression of IGF1 mRNA CTD PMID:23483914 zinc atom increases expression ISO RGD:70506 6480464 Zinc deficiency results in increased expression of IGF1 mRNA CTD PMID:18356318 zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of IGF1 mRNA, Zinc deficiency results in increased expression of IGF1 protein CTD PMID:12672911 more ... zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of IGF1 mRNA, Zinc deficiency results in decreased expression of IGF1 protein CTD PMID:10985758 more ... zinc sulfate multiple interactions EXP 6480464 Pentetic Acid inhibits the reaction [Zinc Sulfate results in decreased expression of IGF1 mRNA], Zinc Sulfate affects the reaction [GH protein results in increased expression of IGF1 mRNA] CTD PMID:9685221 zinc sulfate decreases expression EXP 6480464 Zinc Sulfate results in decreased expression of IGF1 mRNA CTD PMID:9685221 zinc(0) increases import ISO RGD:10765 6480464 IGF1 protein results in increased import of Zinc CTD PMID:16443356 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of IGF1 mRNA, Zinc deficiency results in increased expression of IGF1 protein CTD PMID:12672911 more ... zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of IGF1 mRNA, Zinc deficiency results in decreased expression of IGF1 protein CTD PMID:10985758 more ... zinc(0) increases expression ISO RGD:70506 6480464 Zinc deficiency results in increased expression of IGF1 mRNA CTD PMID:18356318 zinc(0) multiple interactions ISO RGD:10765 6480464 [Zinc binds to calcium silicate] which results in increased expression of IGF1 mRNA CTD PMID:23483914 zinc(0) multiple interactions ISO RGD:70506 6480464 Zinc promotes the reaction [IGF1 protein binds to IGF1R protein] CTD PMID:9648927 zoledronic acid multiple interactions ISO RGD:70506 6480464 [zoledronic acid co-treated with fluvastatin] results in increased expression of IGF1 mRNA CTD PMID:16996129
Gene-Chemical Interaction Annotations