1,2-dimethylhydrazine multiple interactions ISO Metap2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of METAP2 mRNA CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO Metap2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of METAP2 mRNA CTD PMID:22206623 17alpha-ethynylestradiol increases expression ISO Metap2 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of METAP2 mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO Metap2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of METAP2 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of METAP2 mRNA CTD PMID:26496021 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Metap2 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of METAP2 mRNA and AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of METAP2 mRNA] CTD PMID:15034205 and PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of METAP2 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Metap2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of METAP2 mRNA CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Metap2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of METAP2 mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of METAP2 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of METAP2 mRNA CTD PMID:21346803 2-butoxyethanol increases expression ISO Metap2 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of METAP2 mRNA CTD PMID:19812364 2-methylcholine affects expression ISO METAP2 (Homo sapiens) 6480464 beta-methylcholine affects the expression of METAP2 mRNA CTD PMID:21179406 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of METAP2 protein CTD PMID:34915118 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of METAP2 mRNA CTD PMID:19162173 5-fluorouracil multiple interactions ISO METAP2 (Homo sapiens) 6480464 TP53 protein affects the reaction [Fluorouracil results in decreased expression of METAP2 mRNA] CTD PMID:15016801 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of METAP2 mRNA CTD PMID:31881176 all-trans-retinoic acid decreases expression ISO METAP2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of METAP2 mRNA CTD PMID:33167477 Allylamine affects expression EXP 6480464 Allylamine affects the expression of METAP2 mRNA CTD PMID:15910882 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of METAP2 mRNA CTD PMID:16483693 aristolochic acid A increases expression ISO METAP2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of METAP2 protein CTD PMID:33212167 Aroclor 1254 decreases expression ISO Metap2 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of METAP2 mRNA CTD PMID:23650126 benzatropine multiple interactions ISO METAP2 (Homo sapiens) 6480464 [Cuprizone co-treated with Benztropine] results in decreased expression of METAP2 protein CTD PMID:34122009 benzo[a]pyrene decreases expression ISO Metap2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of METAP2 mRNA CTD PMID:17942131 benzo[a]pyrene increases expression ISO Metap2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of METAP2 mRNA CTD PMID:15034205 and PMID:22228805 benzo[a]pyrene multiple interactions ISO Metap2 (Mus musculus) 6480464 AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of METAP2 mRNA] CTD PMID:15034205 benzo[a]pyrene diol epoxide I increases expression ISO METAP2 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of METAP2 promoter CTD PMID:23359474 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of METAP2 promoter and [bisphenol A co-treated with Estradiol] results in decreased expression of METAP2 mRNA CTD PMID:23359474 and PMID:26496021 bisphenol A decreases methylation ISO METAP2 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of METAP2 gene CTD PMID:31601247 bisphenol A decreases expression ISO Metap2 (Mus musculus) 6480464 bisphenol A results in decreased expression of METAP2 mRNA CTD PMID:33221593 bisphenol A decreases expression ISO METAP2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of METAP2 mRNA and bisphenol A results in decreased expression of METAP2 protein CTD PMID:29275510 and PMID:37567409 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of METAP2 mRNA CTD PMID:30816183 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of METAP2 mRNA CTD PMID:25181051 bisphenol F increases expression ISO METAP2 (Homo sapiens) 6480464 bisphenol F results in increased expression of METAP2 protein CTD PMID:34186270 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of METAP2 mRNA CTD PMID:12628495 carbon nanotube increases expression ISO Metap2 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 chloropicrin increases expression ISO METAP2 (Homo sapiens) 6480464 chloropicrin results in increased expression of METAP2 mRNA CTD PMID:26352163 cobalt atom affects binding ISO METAP2 (Homo sapiens) 6480464 METAP2 protein binds to Cobalt CTD PMID:14534293 cobalt atom increases activity ISO METAP2 (Homo sapiens) 6480464 Cobalt results in increased activity of METAP2 protein CTD PMID:15516829 cobalt dichloride increases activity ISO METAP2 (Homo sapiens) 6480464 cobaltous chloride results in increased activity of METAP2 protein CTD PMID:12718546 coumarin increases phosphorylation ISO METAP2 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of METAP2 protein CTD PMID:35688186 coumestrol multiple interactions ISO METAP2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of METAP2 mRNA CTD PMID:19167446 coumestrol decreases expression ISO METAP2 (Homo sapiens) 6480464 Coumestrol results in decreased expression of METAP2 mRNA CTD PMID:19167446 Cuprizon multiple interactions ISO METAP2 (Homo sapiens) 6480464 [Cuprizone co-treated with Benztropine] results in decreased expression of METAP2 protein CTD PMID:34122009 cyclosporin A decreases expression ISO Metap2 (Mus musculus) 6480464 Cyclosporine results in decreased expression of METAP2 mRNA CTD PMID:17942131 dibutyl phthalate decreases expression ISO Metap2 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of METAP2 mRNA CTD PMID:17361019 and PMID:21266533 dibutyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of METAP2 promoter CTD PMID:23359474 dicrotophos decreases expression ISO METAP2 (Homo sapiens) 6480464 dicrotophos results in decreased expression of METAP2 mRNA CTD PMID:28302478 dioxygen increases expression ISO Metap2 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of METAP2 mRNA CTD PMID:22629407 dioxygen multiple interactions ISO Metap2 (Mus musculus) 6480464 Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of METAP2 mRNA] CTD PMID:22629407 diuron increases expression EXP 6480464 Diuron results in increased expression of METAP2 mRNA CTD PMID:21551480 doxorubicin decreases expression ISO METAP2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of METAP2 mRNA CTD PMID:16404146 elemental selenium decreases expression ISO METAP2 (Homo sapiens) 6480464 Selenium results in decreased expression of METAP2 mRNA CTD PMID:19244175 Enterolactone multiple interactions ISO METAP2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of METAP2 mRNA CTD PMID:19167446 ethanol affects splicing ISO Metap2 (Mus musculus) 6480464 Ethanol affects the splicing of METAP2 mRNA CTD PMID:30319688 ethyl methanesulfonate decreases expression ISO METAP2 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of METAP2 mRNA CTD PMID:23649840 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of METAP2 mRNA CTD PMID:18035473 flutamide increases expression EXP 6480464 Flutamide results in increased expression of METAP2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO Metap2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of METAP2 mRNA CTD PMID:22206623 folic acid decreases expression ISO Metap2 (Mus musculus) 6480464 Folic Acid results in decreased expression of METAP2 mRNA CTD PMID:25629700 formaldehyde decreases expression ISO METAP2 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of METAP2 mRNA CTD PMID:23649840 FR900359 decreases phosphorylation ISO METAP2 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of METAP2 protein CTD PMID:37730182 fumagillin multiple interactions EXP 6480464 fumagillin promotes the reaction [Diethylnitrosamine results in increased expression of METAP2 mRNA] CTD PMID:15682466 fumagillin decreases activity ISO METAP2 (Homo sapiens) 6480464 fumagillin results in decreased activity of METAP2 protein CTD PMID:14534293 and PMID:15516829 fumagillin multiple interactions ISO METAP2 (Homo sapiens) 6480464 [fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein CTD PMID:14534293 furan increases methylation EXP 6480464 furan results in increased methylation of METAP2 gene CTD PMID:22079235 gold atom decreases expression ISO METAP2 (Homo sapiens) 6480464 Gold analog results in decreased expression of METAP2 mRNA and Gold results in decreased expression of METAP2 mRNA CTD PMID:25523186 and PMID:36057382 gold(0) decreases expression ISO METAP2 (Homo sapiens) 6480464 Gold analog results in decreased expression of METAP2 mRNA and Gold results in decreased expression of METAP2 mRNA CTD PMID:25523186 and PMID:36057382 ivermectin decreases expression ISO METAP2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of METAP2 protein CTD PMID:32959892 L-ethionine decreases activity ISO METAP2 (Homo sapiens) 6480464 Ethionine metabolite results in decreased activity of METAP2 protein CTD PMID:12718546 lipopolysaccharide increases expression ISO METAP2 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of METAP2 mRNA CTD PMID:35953652 manganese(II) chloride multiple interactions ISO METAP2 (Homo sapiens) 6480464 manganese chloride inhibits the reaction [Triazoles results in decreased activity of METAP2 protein] CTD PMID:12718546 manganese(II) chloride increases activity ISO METAP2 (Homo sapiens) 6480464 manganese chloride results in increased activity of METAP2 protein CTD PMID:12718546 Mesaconitine increases expression EXP 6480464 mesaconitine results in increased expression of METAP2 protein CTD PMID:37182599 methylparaben decreases expression ISO METAP2 (Homo sapiens) 6480464 methylparaben results in decreased expression of METAP2 mRNA CTD PMID:31745603 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of METAP2 mRNA CTD PMID:15682466 N-nitrosodiethylamine multiple interactions EXP 6480464 fumagillin promotes the reaction [Diethylnitrosamine results in increased expression of METAP2 mRNA] CTD PMID:15682466 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of METAP2 mRNA CTD PMID:24136188 nitroxoline decreases activity ISO METAP2 (Homo sapiens) 6480464 nitroxoline results in decreased activity of METAP2 protein CTD PMID:21088277 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of METAP2 mRNA CTD PMID:25729387 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of METAP2 mRNA CTD PMID:25729387 paracetamol decreases expression ISO Metap2 (Mus musculus) 6480464 Acetaminophen results in decreased expression of METAP2 mRNA CTD PMID:17942131 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of METAP2 mRNA CTD PMID:33387578 paracetamol decreases expression ISO METAP2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of METAP2 mRNA CTD PMID:21420995 paracetamol affects expression ISO Metap2 (Mus musculus) 6480464 Acetaminophen affects the expression of METAP2 mRNA CTD PMID:17562736 pentachlorophenol increases expression ISO Metap2 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of METAP2 mRNA CTD PMID:23892564 pinosylvin decreases expression ISO METAP2 (Homo sapiens) 6480464 pinosylvin results in decreased expression of METAP2 mRNA CTD PMID:23333577 progesterone decreases expression ISO METAP2 (Homo sapiens) 6480464 Progesterone results in decreased expression of METAP2 mRNA CTD PMID:18070364 resveratrol decreases expression ISO Metap2 (Mus musculus) 6480464 resveratrol results in decreased expression of METAP2 protein CTD PMID:25505154 resveratrol multiple interactions ISO METAP2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of METAP2 mRNA CTD PMID:23557933 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of METAP2 protein CTD PMID:35544339 SB 431542 multiple interactions ISO METAP2 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of METAP2 protein CTD PMID:37664457 selenium atom decreases expression ISO METAP2 (Homo sapiens) 6480464 Selenium results in decreased expression of METAP2 mRNA CTD PMID:19244175 sodium arsenite decreases expression ISO METAP2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of METAP2 protein CTD PMID:30528433 temozolomide increases expression ISO METAP2 (Homo sapiens) 6480464 Temozolomide results in increased expression of METAP2 mRNA CTD PMID:31758290 tetrahydropalmatine decreases expression ISO METAP2 (Homo sapiens) 6480464 tetrahydropalmatine results in decreased expression of METAP2 protein CTD PMID:20109541 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of METAP2 mRNA CTD PMID:23411599 and PMID:34492290 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of METAP2 mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of METAP2 mRNA CTD PMID:25729387 trans-pinosylvin decreases expression ISO METAP2 (Homo sapiens) 6480464 pinosylvin results in decreased expression of METAP2 mRNA CTD PMID:23333577 triazoles multiple interactions ISO METAP2 (Homo sapiens) 6480464 manganese chloride inhibits the reaction [Triazoles results in decreased activity of METAP2 protein] CTD PMID:12718546 triazoles decreases activity ISO METAP2 (Homo sapiens) 6480464 Triazoles results in decreased activity of METAP2 protein CTD PMID:12718546 and PMID:15516829 Tributyltin oxide decreases expression ISO Metap2 (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in decreased expression of METAP2 mRNA CTD PMID:17942131 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of METAP2 mRNA CTD PMID:33387578 trimellitic anhydride increases expression ISO Metap2 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of METAP2 mRNA CTD PMID:19042947 troglitazone decreases expression ISO Metap2 (Mus musculus) 6480464 troglitazone results in decreased expression of METAP2 mRNA CTD PMID:28973697 uranium atom affects expression ISO METAP2 (Homo sapiens) 6480464 Uranium affects the expression of METAP2 mRNA CTD PMID:15672453 valproic acid increases expression ISO METAP2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of METAP2 mRNA CTD PMID:23179753 vitamin E decreases expression ISO METAP2 (Homo sapiens) 6480464 Vitamin E results in decreased expression of METAP2 mRNA CTD PMID:19244175