Ankrd24 (ankyrin repeat domain 24) - Rat Genome Database

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Gene: Ankrd24 (ankyrin repeat domain 24) Rattus norvegicus
Analyze
Symbol: Ankrd24
Name: ankyrin repeat domain 24
RGD ID: 1311385
Description: Predicted to be involved in auditory receptor cell stereocilium organization and sensory perception of sound. Predicted to be located in plasma membrane and stereocilium. Orthologous to human ANKRD24 (ankyrin repeat domain 24); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ankyrin repeat domain-containing protein 24; ankyrin repeat domain-containing protein 24-like; LOC100909645; LOC299639
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,712,720 - 8,731,910 (-)NCBIGRCr8
mRatBN7.278,061,634 - 8,081,142 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,061,953 - 8,081,142 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx710,948,415 - 10,967,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0712,824,079 - 12,843,227 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,691,289 - 10,710,616 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0710,917,359 - 10,937,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl710,917,367 - 10,936,415 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,086,844 - 11,105,541 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,534,366 - 9,554,062 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,534,367 - 9,553,126 (-)NCBI
Celera76,252,939 - 6,272,218 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ankrd24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,712,720 - 8,731,910 (-)NCBIGRCr8
mRatBN7.278,061,634 - 8,081,142 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,061,953 - 8,081,142 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx710,948,415 - 10,967,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0712,824,079 - 12,843,227 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,691,289 - 10,710,616 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0710,917,359 - 10,937,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl710,917,367 - 10,936,415 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,086,844 - 11,105,541 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,534,366 - 9,554,062 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,534,367 - 9,553,126 (-)NCBI
Celera76,252,939 - 6,272,218 (-)NCBICelera
Cytogenetic Map7q11NCBI
ANKRD24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,182,689 - 4,224,814 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,182,689 - 4,224,814 (+)EnsemblGRCh38hg38GRCh38
GRCh37194,182,686 - 4,224,811 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,134,351 - 4,175,811 (+)NCBINCBI36Build 36hg18NCBI36
Celera194,122,806 - 4,164,282 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,946,703 - 3,987,932 (+)NCBIHuRef
CHM1_1194,182,897 - 4,224,911 (+)NCBICHM1_1
T2T-CHM13v2.0194,165,992 - 4,208,117 (+)NCBIT2T-CHM13v2.0
Ankrd24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,464,352 - 81,483,446 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,464,374 - 81,483,444 (+)EnsemblGRCm39 Ensembl
GRCm381081,627,821 - 81,647,612 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,628,540 - 81,647,610 (+)EnsemblGRCm38mm10GRCm38
MGSCv371081,091,285 - 81,110,357 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361081,031,764 - 81,050,739 (+)NCBIMGSCv36mm8
Celera1082,651,719 - 82,670,799 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Ankrd24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554954,621,059 - 4,636,235 (-)NCBIChiLan1.0ChiLan1.0
ANKRD24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,580,194 - 8,620,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,810,324 - 7,851,035 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,206,152 - 3,246,886 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,169,761 - 4,194,635 (+)NCBIpanpan1.1PanPan1.1panPan2
ANKRD24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,391,381 - 55,404,538 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,391,652 - 55,404,544 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,118,278 - 55,144,091 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,049,533 - 56,075,317 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,050,846 - 56,072,131 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,109,392 - 55,133,079 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,590,607 - 55,614,260 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,789,482 - 55,815,285 (-)NCBIUU_Cfam_GSD_1.0
Ankrd24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,415,503 - 215,432,157 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365882,403,454 - 2,419,279 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKRD24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,540,870 - 74,567,837 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,540,868 - 74,568,402 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,035,515 - 75,063,029 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANKRD24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,932,677 - 3,972,476 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,949,211 - 3,972,176 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660814,243,188 - 4,286,177 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ankrd24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248285,410,032 - 5,441,824 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ankrd24
88 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:148
Count of miRNA genes:122
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000008882
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat

Markers in Region
RH144238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,065,777 - 8,065,883 (+)MAPPERmRatBN7.2
Rnor_6.099,934,867 - 9,934,972NCBIRnor6.0
Rnor_6.0710,921,186 - 10,921,291NCBIRnor6.0
Rnor_5.0711,090,671 - 11,090,776UniSTSRnor5.0
Rnor_5.098,935,294 - 8,935,399UniSTSRnor5.0
RGSC_v3.479,538,192 - 9,538,297UniSTSRGSC3.4
Celera76,256,764 - 6,256,869UniSTS
Cytogenetic Map7q11UniSTS
RH137268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,061,965 - 8,062,126 (+)MAPPERmRatBN7.2
Rnor_6.0710,917,374 - 10,917,534NCBIRnor6.0
Rnor_6.099,931,054 - 9,931,214NCBIRnor6.0
Rnor_5.0711,086,859 - 11,087,019UniSTSRnor5.0
Rnor_5.098,931,481 - 8,931,641UniSTSRnor5.0
RGSC_v3.479,534,379 - 9,534,539UniSTSRGSC3.4
Celera76,252,952 - 6,253,112UniSTS
Cytogenetic Map7q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 43 57 41 19 41 8 11 74 35 34 11 8
Below cutoff 7

Sequence


RefSeq Acc Id: ENSRNOT00000008882   ⟹   ENSRNOP00000008882
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,061,953 - 8,081,142 (-)Ensembl
Rnor_6.0 Ensembl710,917,367 - 10,936,415 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000067585   ⟹   ENSRNOP00000062163
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl78,061,953 - 8,081,142 (-)Ensembl
RefSeq Acc Id: NM_001106771   ⟹   NP_001100241
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,712,722 - 8,731,910 (-)NCBI
mRatBN7.278,061,953 - 8,081,142 (-)NCBI
Rnor_6.0710,917,361 - 10,936,415 (-)NCBI
Rnor_5.0711,086,844 - 11,105,541 (-)NCBI
RGSC_v3.479,534,366 - 9,554,062 (-)RGD
Celera76,252,939 - 6,272,218 (-)RGD
Sequence:
RefSeq Acc Id: XM_063263189   ⟹   XP_063119259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,712,720 - 8,731,905 (-)NCBI
RefSeq Acc Id: NP_001100241   ⟸   NM_001106771
- UniProtKB: D3ZCC5 (UniProtKB/TrEMBL),   A6K857 (UniProtKB/TrEMBL),   A6K858 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000008882   ⟸   ENSRNOT00000008882
RefSeq Acc Id: ENSRNOP00000062163   ⟸   ENSRNOT00000067585
RefSeq Acc Id: XP_063119259   ⟸   XM_063263189
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z908-F1-model_v2 AlphaFold D3Z908 1-527 view protein structure
AF-D3ZCC5-F1-model_v2 AlphaFold D3ZCC5 1-903 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311385 AgrOrtholog
BioCyc Gene G2FUF-35047 BioCyc
Ensembl Genes ENSRNOG00000006759 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008882 ENTREZGENE
  ENSRNOT00000008882.7 UniProtKB/TrEMBL
  ENSRNOT00000067585.4 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  RAI14/UACA UniProtKB/TrEMBL
KEGG Report rno:299639 UniProtKB/TrEMBL
NCBI Gene 299639 ENTREZGENE
PANTHER ANKYCORBIN UniProtKB/TrEMBL
  ANKYCORBIN UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
PhenoGen Ankrd24 PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006759 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A6K857 ENTREZGENE, UniProtKB/TrEMBL
  A6K858 ENTREZGENE, UniProtKB/TrEMBL
  D3Z908_RAT UniProtKB/TrEMBL
  D3ZCC5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ankrd24  ankyrin repeat domain 24  LOC100909645  ankyrin repeat domain-containing protein 24-like  Data merged from RGD:6502816 737654 PROVISIONAL
2012-07-05 LOC100909645  ankyrin repeat domain-containing protein 24-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Ankrd24  ankyrin repeat domain 24   Ankrd24_predicted  ankyrin repeat domain 24 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ankrd24_predicted  ankyrin repeat domain 24 (predicted)      Symbol and Name status set to approved 70820 APPROVED