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Gene: Gns (glucosamine (N-acetyl)-6-sulfatase) Rattus norvegicus
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Symbol: Gns
Name: glucosamine (N-acetyl)-6-sulfatase
Description: Exhibits N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan binding activity; and sulfate binding activity. Involved in keratan sulfate catabolic process. Localizes to the lysosome. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase); PARTICIPATES IN glycosaminoglycan degradation pathway; INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC299825; N-acetylglucosamine-6-sulfatase
Orthologs:
Homo sapiens (human) : GNS (glucosamine (N-acetyl)-6-sulfatase)  HGNC  Alliance
Mus musculus (house mouse) : Gns (glucosamine (N-acetyl)-6-sulfatase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Canis lupus familiaris (dog) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Sus scrofa (pig) : GNS (glucosamine (N-acetyl)-6-sulfatase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0763,467,027 - 63,501,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0763,690,750 - 63,724,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,672,492 - 60,702,306 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1760,693,221 - 60,723,036 (+)NCBI
Celera753,633,706 - 53,657,136 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gns
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1305877
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.