Gns (glucosamine (N-acetyl)-6-sulfatase) - Rat Genome Database

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Gene: Gns (glucosamine (N-acetyl)-6-sulfatase) Rattus norvegicus
Analyze
Symbol: Gns
Name: glucosamine (N-acetyl)-6-sulfatase
RGD ID: 1305877
Description: Enables N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan binding activity; and sulfate binding activity. Involved in keratan sulfate catabolic process. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIID. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase); PARTICIPATES IN glycosaminoglycan degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100909505; LOC299825; N-acetylglucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2756,889,148 - 56,923,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl756,889,232 - 56,923,151 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx758,800,291 - 58,829,841 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0761,003,226 - 61,032,786 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0760,780,851 - 60,810,415 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0763,467,027 - 63,501,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl763,467,216 - 63,499,353 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl765,616,177 - 65,653,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0763,690,750 - 63,724,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,672,492 - 60,702,306 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1760,693,221 - 60,723,036 (+)NCBI
Celera753,633,706 - 53,657,136 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
lysosome  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate. Fuchs W, etal., Eur J Biochem. 1985 Sep 16;151(3):551-6.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Genomic basis of mucopolysaccharidosis type IIID (MIM 252940) revealed by sequencing of GNS encoding N-acetylglucosamine-6-sulfatase. Mok A, etal., Genomics. 2003 Jan;81(1):1-5.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15962010   PMID:16174644   PMID:23376485   PMID:23533145   PMID:29514215  


Genomics

Comparative Map Data
Gns
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2756,889,148 - 56,923,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl756,889,232 - 56,923,151 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx758,800,291 - 58,829,841 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0761,003,226 - 61,032,786 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0760,780,851 - 60,810,415 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0763,467,027 - 63,501,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl763,467,216 - 63,499,353 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl765,616,177 - 65,653,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0763,690,750 - 63,724,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,672,492 - 60,702,306 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1760,693,221 - 60,723,036 (+)NCBI
Celera753,633,706 - 53,657,136 (+)NCBICelera
Cytogenetic Map7q22NCBI
GNS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381264,713,449 - 64,759,406 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1264,713,445 - 64,759,431 (-)EnsemblGRCh38hg38GRCh38
GRCh371265,107,229 - 65,153,186 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361263,393,489 - 63,439,479 (-)NCBINCBI36Build 36hg18NCBI36
Build 341263,393,490 - 63,439,479NCBI
Celera1264,772,049 - 64,818,041 (-)NCBICelera
Cytogenetic Map12q14.3NCBI
HuRef1262,157,915 - 62,203,861 (-)NCBIHuRef
CHM1_11265,074,143 - 65,120,149 (-)NCBICHM1_1
T2T-CHM13v2.01264,692,475 - 64,738,233 (-)NCBIT2T-CHM13v2.0
Gns
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910121,200,995 - 121,233,159 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10121,200,995 - 121,233,154 (+)EnsemblGRCm39 Ensembl
GRCm3810121,365,090 - 121,397,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,365,090 - 121,397,249 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710120,802,146 - 120,834,301 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610120,768,150 - 120,800,305 (+)NCBIMGSCv36mm8
Celera10123,737,286 - 123,777,799 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1069.62NCBI
Gns
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545811,471,376 - 11,500,838 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545811,471,376 - 11,500,793 (-)NCBIChiLan1.0ChiLan1.0
GNS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11229,606,360 - 29,652,210 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01224,164,127 - 24,209,963 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11224,667,603 - 24,712,939 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1224,667,603 - 24,712,939 (+)Ensemblpanpan1.1panPan2
GNS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1107,363,628 - 7,415,618 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl107,366,247 - 7,507,270 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha107,299,232 - 7,351,429 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0107,474,090 - 7,526,469 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl107,449,649 - 7,526,493 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1107,339,256 - 7,391,535 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0107,591,891 - 7,644,088 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0107,722,471 - 7,774,680 (-)NCBIUU_Cfam_GSD_1.0
Gns
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494551,099,523 - 51,137,683 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365452,971,870 - 3,010,566 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365452,974,627 - 3,010,586 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl529,128,760 - 29,190,230 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1529,128,754 - 29,190,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2532,134,222 - 32,173,457 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11160,390,479 - 60,434,266 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1160,388,883 - 60,434,233 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037185,341,130 - 185,386,269 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gns
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248023,636,906 - 3,666,033 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248023,637,250 - 3,668,698 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gns
176 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:127
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000006566, ENSRNOT00000064349
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat

Markers in Region
RH132435  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2756,917,307 - 56,918,843 (+)MAPPERmRatBN7.2
Rnor_6.0765,647,178 - 65,648,713NCBIRnor6.0
Rnor_6.0763,495,193 - 63,496,728NCBIRnor6.0
Rnor_5.0763,719,083 - 63,720,618UniSTSRnor5.0
Rnor_5.0765,855,119 - 65,856,654UniSTSRnor5.0
RGSC_v3.4760,700,564 - 60,702,099UniSTSRGSC3.4
RH 3.4 Map7501.5UniSTS
Cytogenetic Map7q22UniSTS
AU046507  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2756,909,948 - 56,910,093 (+)MAPPERmRatBN7.2
Rnor_6.0765,637,111 - 65,637,255NCBIRnor6.0
Rnor_6.0763,487,835 - 63,487,979NCBIRnor6.0
Rnor_5.0763,711,725 - 63,711,869UniSTSRnor5.0
Rnor_5.0765,845,052 - 65,845,196UniSTSRnor5.0
RGSC_v3.4760,693,205 - 60,693,349UniSTSRGSC3.4
Celera753,654,423 - 53,654,567UniSTS
Cytogenetic Map7q22UniSTS


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000006566   ⟹   ENSRNOP00000006566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl756,894,902 - 56,923,151 (+)Ensembl
Rnor_6.0 Ensembl765,616,177 - 65,653,052 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000064349   ⟹   ENSRNOP00000062823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl756,889,232 - 56,923,151 (+)Ensembl
Rnor_6.0 Ensembl763,467,216 - 63,499,353 (+)Ensembl
RefSeq Acc Id: NM_001011989   ⟹   NP_001011989
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2756,889,148 - 56,919,050 (+)NCBI
Rnor_6.0763,467,122 - 63,496,935 (+)NCBI
Rnor_5.0763,690,750 - 63,724,944 (+)NCBI
RGSC_v3.4760,672,492 - 60,702,306 (+)RGD
Celera753,633,706 - 53,657,136 (+)RGD
Sequence:
RefSeq Acc Id: NM_001414922   ⟹   NP_001401851
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2756,889,148 - 56,923,173 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001011989 (Get FASTA)   NCBI Sequence Viewer  
  NP_001401851 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87741 (Get FASTA)   NCBI Sequence Viewer  
  CAI84988 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006566.8
  ENSRNOP00000062823
  ENSRNOP00000062823.4
RefSeq Acc Id: NP_001011989   ⟸   NM_001011989
- Peptide Label: isoform 2 precursor
- UniProtKB: Q5M918 (UniProtKB/TrEMBL),   A0A8J8YF65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000062823   ⟸   ENSRNOT00000064349
RefSeq Acc Id: ENSRNOP00000006566   ⟸   ENSRNOT00000006566
RefSeq Acc Id: NP_001401851   ⟸   NM_001414922
- Peptide Label: isoform 1 precursor
- UniProtKB: F7F393 (UniProtKB/TrEMBL),   F7EQ81 (UniProtKB/TrEMBL),   Q32KJ5 (UniProtKB/TrEMBL),   A0A8J8YF65 (UniProtKB/TrEMBL)
Protein Domains
Sulfatase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q32KJ5-F1-model_v2 AlphaFold Q32KJ5 1-544 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305877 AgrOrtholog
BioCyc Gene G2FUF-33873 BioCyc
Ensembl Genes ENSRNOG00000046159 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000047350 Ensembl
Ensembl Transcript ENSRNOT00000006566.7 UniProtKB/TrEMBL
  ENSRNOT00000064349 ENTREZGENE
  ENSRNOT00000064349.4 UniProtKB/TrEMBL
Gene3D-CATH 3.40.720.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7314130 IMAGE-MGC_LOAD
InterPro Alkaline_phosphatase_core UniProtKB/TrEMBL
  GlcNAc_6-SO4ase UniProtKB/TrEMBL
  Sulfatase UniProtKB/TrEMBL
  Sulfatase_CS UniProtKB/TrEMBL
KEGG Report rno:299825 UniProtKB/TrEMBL
MGC_CLONE MGC:105737 IMAGE-MGC_LOAD
NCBI Gene 299825 ENTREZGENE
PANTHER N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER UniProtKB/TrEMBL
  PTHR43108:SF5 UniProtKB/TrEMBL
Pfam Sulfatase UniProtKB/TrEMBL
PhenoGen Gns PhenoGen
PIRSF G6S UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  SULFATASE_1 UniProtKB/TrEMBL
  SULFATASE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046159 RatGTEx
  ENSRNOG00000047350 RatGTEx
Superfamily-SCOP Alkaline_phosphatase_core UniProtKB/TrEMBL
UniProt A0A8J8YF65 ENTREZGENE, UniProtKB/TrEMBL
  F7EQ81 ENTREZGENE
  F7F393 ENTREZGENE
  Q32KJ5 ENTREZGENE, UniProtKB/TrEMBL
  Q5M918 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F7EQ81 UniProtKB/TrEMBL
  F7F393 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Gns  glucosamine (N-acetyl)-6-sulfatase  LOC100909505  N-acetylglucosamine-6-sulfatase-like  Data merged from RGD:6503308 737654 PROVISIONAL
2013-05-24 Gns  glucosamine (N-acetyl)-6-sulfatase  LOC688338  similar to glucosamine (N-acetyl)-6-sulfatase  Data merged from RGD:1590034 1643240 APPROVED
2012-07-05 LOC100909505  N-acetylglucosamine-6-sulfatase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC688338  similar to glucosamine (N-acetyl)-6-sulfatase      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Gns  glucosamine (N-acetyl)-6-sulfatase  Gns_predicted  glucosamine (N-acetyl)-6-sulfatase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gns_predicted  glucosamine (N-acetyl)-6-sulfatase (predicted)      Symbol and Name status set to approved 70820 APPROVED