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Gene: Gns (glucosamine (N-acetyl)-6-sulfatase) Mus musculus
Symbol: Gns
Name: glucosamine (N-acetyl)-6-sulfatase
RGD ID: 1314173
Description: Predicted to have N-acetylglucosamine-6-sulfatase activity; glycosaminoglycan binding activity; and sulfate binding activity. Predicted to be involved in glycosaminoglycan metabolic process. Localizes to lysosome. Is expressed in several structures, including eye; nervous system; skeleton; and spleen primordium. Used to study mucopolysaccharidosis III. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIID. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; isoprenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610016K11Rik; AU042285; C87209; G6; G6S; glucosamine-6-sulfatase; N-acetylglucosamine-6-sulfatase; N28088
Homo sapiens (human) : GNS (glucosamine (N-acetyl)-6-sulfatase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gns (glucosamine (N-acetyl)-6-sulfatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Canis lupus familiaris (dog) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gns (glucosamine (N-acetyl)-6-sulfatase)
Sus scrofa (pig) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Chlorocebus sabaeus (African green monkey) : GNS (glucosamine (N-acetyl)-6-sulfatase)
Heterocephalus glaber (naked mole-rat) : Gns (glucosamine (N-acetyl)-6-sulfatase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3910121,200,995 - 121,233,159 (+)NCBI
GRCm3810121,365,090 - 121,397,254 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10121,365,090 - 121,397,249 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710120,802,146 - 120,834,301 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610120,768,150 - 120,800,305 (+)NCBImm8
Celera10123,737,286 - 123,777,799 (+)NCBICelera
Cytogenetic Map10D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gns
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314173
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.