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Gene: Tdg (thymine-DNA glycosylase) Rattus norvegicus
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Symbol: Tdg
Name: thymine-DNA glycosylase
Description: Exhibits protein domain specific binding activity and transcription factor binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Predicted to colocalize with the PML body. Orthologous to human TDG (thymine DNA glycosylase); PARTICIPATES IN base excision repair pathway; INTERACTS WITH (+)-pilocarpine; 1,2,4-trimethylbenzene; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G/T mismatch-specific thymine DNA glycosylase
Orthologs:
Homo sapiens (human) : TDG (thymine DNA glycosylase)  HGNC  Alliance
Mus musculus (house mouse) : Tdg (thymine DNA glycosylase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdg (thymine DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : TDG (thymine DNA glycosylase)
Canis lupus familiaris (dog) : TDG (thymine DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdg (thymine DNA glycosylase)
Sus scrofa (pig) : TDG (thymine DNA glycosylase)
more info ...
Related Pseudogenes: Tdg-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0727,194,000 - 27,213,676 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0727,313,355 - 27,333,031 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,300,450 - 23,320,095 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1723,320,723 - 23,340,366 (-)NCBI
Celera718,257,668 - 18,277,353 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tdg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620959
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.