Rps12l4 (ribosomal protein S12-like 4) - Rat Genome Database

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Gene: Rps12l4 (ribosomal protein S12-like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps12l4
Name: ribosomal protein S12-like 4
RGD ID: 1561102
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in maintenance of translational fidelity and ribosomal small subunit biogenesis. Predicted to be part of cytosolic small ribosomal subunit; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; furan.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: hypothetical protein LOC299713; LOC299713; RGD1561102; similar to ribosomal protein S12; uncharacterized protein LOC299713
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8725,006,242 - 25,007,029 (-)NCBIGRCr8
mRatBN7.2723,118,845 - 23,119,632 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl723,118,845 - 23,119,632 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx725,113,407 - 25,114,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,276,109 - 27,276,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,053,147 - 27,053,934 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,281,252 - 29,282,039 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,281,252 - 29,282,039 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0729,383,629 - 29,384,416 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,402,762 - 25,403,549 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera720,277,965 - 20,278,752 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rps12l4
6 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:96
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000067777
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6
Low 1 30 26 10 18 10 8 8 70 34 34 11 8
Below cutoff 2 13 31 31 1 31 3 4 1

Sequence


RefSeq Acc Id: ENSRNOT00000067777   ⟹   ENSRNOP00000063201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl723,118,845 - 23,119,632 (-)Ensembl
Rnor_6.0 Ensembl729,281,252 - 29,282,039 (-)Ensembl
RefSeq Acc Id: NM_001106777   ⟹   NP_001100247
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8725,006,242 - 25,007,029 (-)NCBI
mRatBN7.2723,118,845 - 23,119,632 (-)NCBI
Rnor_6.0729,281,252 - 29,282,039 (-)NCBI
Rnor_5.0729,383,629 - 29,384,416 (-)NCBI
RGSC_v3.4725,402,762 - 25,403,549 (-)RGD
Celera720,277,965 - 20,278,752 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100247 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM16998 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063201
  ENSRNOP00000063201.1
  ENSRNOP00000092043.1
RefSeq Acc Id: NP_001100247   ⟸   NM_001106777
- UniProtKB: D3ZV36 (UniProtKB/TrEMBL),   A6IFQ0 (UniProtKB/TrEMBL),   A0A8I6ACY4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063201   ⟸   ENSRNOT00000067777
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZV36-F1-model_v2 AlphaFold D3ZV36 1-132 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561102 AgrOrtholog
BioCyc Gene G2FUF-34500 BioCyc
Ensembl Genes ENSRNOG00000016411 UniProtKB/TrEMBL
  ENSRNOG00000043412 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067777 ENTREZGENE
  ENSRNOT00000067777.3 UniProtKB/TrEMBL
  ENSRNOT00000115390.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.30 UniProtKB/TrEMBL
InterPro L30e-like UniProtKB/TrEMBL
  Ribosomal_eS12_CS UniProtKB/TrEMBL
  Ribosomal_L7Ae/L30e/S12e/Gad45 UniProtKB/TrEMBL
  Ribosomal_S12e UniProtKB/TrEMBL
KEGG Report rno:299713 UniProtKB/TrEMBL
NCBI Gene 299713 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S12 UniProtKB/TrEMBL
  40S RIBOSOMAL PROTEIN S12-RELATED UniProtKB/TrEMBL
  Ribosomal_S12e UniProtKB/TrEMBL
Pfam Ribosomal_L7Ae UniProtKB/TrEMBL
PhenoGen Rps12l4 PhenoGen
PRINTS RIBSOMALS12E UniProtKB/TrEMBL
PROSITE RIBOSOMAL_S12E UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016411 RatGTEx
  ENSRNOG00000043412 RatGTEx
Superfamily-SCOP SSF55315 UniProtKB/TrEMBL
UniProt A0A8I6ACY4 ENTREZGENE, UniProtKB/TrEMBL
  A6IFQ0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZV36 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-07 Rps12l4  ribosomal protein S12-like 4  RGD1561102  similar to ribosomal protein S12  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1561102  similar to ribosomal protein S12   RGD1561102_predicted  similar to ribosomal protein S12 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561102_predicted  similar to ribosomal protein S12 (predicted)  LOC299713  similar to ribosomal protein S12  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC299713  similar to ribosomal protein S12      Symbol and Name status set to provisional 70820 PROVISIONAL