Rspo2 (R-spondin 2) - Rat Genome Database

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Pathways
Gene: Rspo2 (R-spondin 2) Rattus norvegicus
Analyze
Symbol: Rspo2
Name: R-spondin 2
RGD ID: 1562331
Description: Predicted to enable heparin binding activity and signaling receptor binding activity. Predicted to be involved in limb development and positive regulation of Wnt signaling pathway. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; negative regulation of odontogenesis of dentin-containing tooth; and respiratory system development. Predicted to be located in cell surface and extracellular region. Human ortholog(s) of this gene implicated in tetraamelia syndrome 2. Orthologous to human RSPO2 (R-spondin 2); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC500863; R-spondin 2 homolog; R-spondin 2 homolog (Xenopus laevis); R-spondin-2; RGD1562331; similar to RIKEN cDNA 2610028F08
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2774,096,378 - 74,239,398 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl774,103,090 - 74,238,933 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx776,004,762 - 76,090,437 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0778,207,236 - 78,292,913 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0778,075,318 - 78,160,987 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0781,919,911 - 82,059,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl781,924,050 - 82,059,789 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0781,937,691 - 82,077,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4778,826,526 - 78,912,786 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera771,160,894 - 71,246,191 (-)NCBICelera
Cytogenetic Map7q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The complex world of WNT receptor signalling. Niehrs C Nat Rev Mol Cell Biol. 2012 Dec;13(12):767-79. doi: 10.1038/nrm3470. Epub 2012 Nov 15.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9596525   PMID:16543246   PMID:18256198   PMID:19213727   PMID:22615920   PMID:24066094   PMID:24616052   PMID:25188337   PMID:29769720  


Genomics

Comparative Map Data
Rspo2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2774,096,378 - 74,239,398 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl774,103,090 - 74,238,933 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx776,004,762 - 76,090,437 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0778,207,236 - 78,292,913 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0778,075,318 - 78,160,987 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0781,919,911 - 82,059,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl781,924,050 - 82,059,789 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0781,937,691 - 82,077,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4778,826,526 - 78,912,786 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera771,160,894 - 71,246,191 (-)NCBICelera
Cytogenetic Map7q31NCBI
RSPO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388107,899,316 - 108,083,620 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8107,899,316 - 108,083,642 (-)EnsemblGRCh38hg38GRCh38
GRCh378108,911,544 - 109,095,848 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368108,980,721 - 109,164,742 (-)NCBINCBI36Build 36hg18NCBI36
Celera8105,098,134 - 105,283,118 (-)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8104,233,209 - 104,418,017 (-)NCBIHuRef
CHM1_18108,951,793 - 109,136,161 (-)NCBICHM1_1
T2T-CHM13v2.08109,027,818 - 109,212,087 (-)NCBIT2T-CHM13v2.0
Rspo2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391542,884,184 - 43,034,990 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1542,884,190 - 43,034,222 (-)EnsemblGRCm39 Ensembl
GRCm381543,020,788 - 43,171,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1543,020,794 - 43,170,826 (-)EnsemblGRCm38mm10GRCm38
MGSCv371542,852,341 - 43,002,364 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361542,850,869 - 43,000,892 (-)NCBIMGSCv36mm8
Celera1543,503,080 - 43,653,511 (-)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1516.73NCBI
Rspo2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541730,643,554 - 30,704,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541730,643,554 - 30,704,497 (-)NCBIChiLan1.0ChiLan1.0
RSPO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan18100,782,739 - 100,968,263 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08104,535,751 - 104,721,463 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18106,685,116 - 106,870,494 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8106,685,116 - 106,870,494 (-)Ensemblpanpan1.1panPan2
RSPO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1138,610,227 - 8,755,727 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl138,611,952 - 8,754,859 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha138,550,551 - 8,728,117 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0138,873,544 - 9,022,401 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl138,874,544 - 9,021,570 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1138,627,417 - 8,772,877 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0138,745,404 - 8,896,677 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0138,823,008 - 8,971,462 (-)NCBIUU_Cfam_GSD_1.0
Rspo2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530329,254,327 - 29,390,001 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647036,681,506 - 36,814,626 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493647036,680,716 - 36,815,347 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RSPO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl429,414,752 - 29,579,674 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1429,415,774 - 29,577,890 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2431,802,835 - 31,967,808 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RSPO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18102,632,060 - 102,804,181 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8102,632,060 - 102,801,911 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603937,778,158 - 37,953,383 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rspo2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476323,067,691 - 23,182,059 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476323,067,682 - 23,182,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rspo2
830 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:551
Count of miRNA genes:275
Interacting mature miRNAs:364
Transcripts:ENSRNOT00000067333
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)753612714103945643Rat
2317035Aia16Adjuvant induced arthritis QTL 162.71joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)759238038104238038Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)761074194106074194Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)762004452101773158Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)762004452101773158Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)768938720113886318Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)768938720113886318Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)768938720113886318Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1357338Stl17Serum triglyceride level QTL 173.23blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)769736356112729554Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat

Markers in Region
RH139502  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2774,102,610 - 74,102,824 (+)MAPPERmRatBN7.2
Rnor_6.0781,924,151 - 81,924,364NCBIRnor6.0
Rnor_5.0781,941,931 - 81,942,144UniSTSRnor5.0
RGSC_v3.4778,774,610 - 78,774,823UniSTSRGSC3.4
Celera771,110,007 - 71,110,220UniSTS
RH 3.4 Map7523.0UniSTS
Cytogenetic Map7q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 2
Low 6 4 4 1 4 62 25 11
Below cutoff 2 29 32 16 17 16 8 9 22 11 8

Sequence


RefSeq Acc Id: ENSRNOT00000067333   ⟹   ENSRNOP00000062362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl774,153,444 - 74,238,803 (-)Ensembl
Rnor_6.0 Ensembl781,974,870 - 82,059,659 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082741   ⟹   ENSRNOP00000069239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl774,103,090 - 74,238,933 (-)Ensembl
Rnor_6.0 Ensembl781,924,630 - 82,059,789 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000087177   ⟹   ENSRNOP00000071706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl781,924,050 - 82,059,247 (-)Ensembl
RefSeq Acc Id: NM_001130575   ⟹   NP_001124047
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2774,153,444 - 74,238,803 (-)NCBI
Rnor_6.0781,974,870 - 82,059,659 (-)NCBI
Rnor_5.0781,937,691 - 82,077,651 (-)NCBI
RGSC_v3.4778,826,526 - 78,912,786 (-)RGD
Celera771,160,894 - 71,246,191 (-)RGD
Sequence:
RefSeq Acc Id: XM_008765454   ⟹   XP_008763676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2774,096,378 - 74,239,398 (-)NCBI
Rnor_6.0781,919,911 - 82,058,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765455   ⟹   XP_008763677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2774,096,378 - 74,239,398 (-)NCBI
Rnor_6.0781,919,911 - 82,059,659 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595050   ⟹   XP_017450539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2774,096,378 - 74,239,398 (-)NCBI
Rnor_6.0781,919,911 - 82,058,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079749   ⟹   XP_038935677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2774,096,378 - 74,239,398 (-)NCBI
RefSeq Acc Id: XM_039079750   ⟹   XP_038935678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2774,096,378 - 74,239,398 (-)NCBI
RefSeq Acc Id: NP_001124047   ⟸   NM_001130575
- Peptide Label: precursor
- UniProtKB: D3ZCB0 (UniProtKB/TrEMBL),   A6HRA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763677   ⟸   XM_008765455
- Peptide Label: isoform X3
- UniProtKB: A6HRA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763676   ⟸   XM_008765454
- Peptide Label: isoform X1
- UniProtKB: I7GAZ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450539   ⟸   XM_017595050
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000062362   ⟸   ENSRNOT00000067333
RefSeq Acc Id: ENSRNOP00000069239   ⟸   ENSRNOT00000082741
RefSeq Acc Id: ENSRNOP00000071706   ⟸   ENSRNOT00000087177
RefSeq Acc Id: XP_038935678   ⟸   XM_039079750
- Peptide Label: isoform X1
- UniProtKB: I7GAZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038935677   ⟸   XM_039079749
- Peptide Label: isoform X1
- UniProtKB: I7GAZ6 (UniProtKB/TrEMBL)
Protein Domains
R-spondin Fu-CRD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-I7GAZ6-F1-model_v2 AlphaFold I7GAZ6 1-250 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562331 AgrOrtholog
BioCyc Gene G2FUF-33494 BioCyc
Ensembl Genes ENSRNOG00000037687 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067333 ENTREZGENE
  ENSRNOT00000067333.2 UniProtKB/TrEMBL
  ENSRNOT00000082741 ENTREZGENE
  ENSRNOT00000082741.2 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
InterPro Furin_repeat UniProtKB/TrEMBL
  Growth_fac_rcpt UniProtKB/TrEMBL
  Rspo_Fu-CRD_dom UniProtKB/TrEMBL
  Thrombospondin_1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
KEGG Report rno:500863 UniProtKB/TrEMBL
NCBI Gene 500863 ENTREZGENE
PANTHER NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  PTHR46987:SF4 UniProtKB/TrEMBL
Pfam Furin-like_2 UniProtKB/TrEMBL
PhenoGen Rspo2 PhenoGen
PROSITE TSP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000037687 RatGTEx
SMART SM00261 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Grow_fac_recept UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
UniProt A6HRA0 ENTREZGENE, UniProtKB/TrEMBL
  A6HRA2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZCB0 ENTREZGENE, UniProtKB/TrEMBL
  I7GAZ6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Rspo2  R-spondin 2  Rspo2  R-spondin 2 homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Rspo2  R-spondin 2 homolog (Xenopus laevis)  RGD1562331_predicted  similar to RIKEN cDNA 2610028F08 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562331_predicted  similar to RIKEN cDNA 2610028F08 (predicted)  LOC500863  similar to RIKEN cDNA 2610028F08  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500863  similar to RIKEN cDNA 2610028F08      Symbol and Name status set to provisional 70820 PROVISIONAL