Ptprr (protein tyrosine phosphatase, receptor type, R) - Rat Genome Database

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Gene: Ptprr (protein tyrosine phosphatase, receptor type, R) Rattus norvegicus
Analyze
Symbol: Ptprr
Name: protein tyrosine phosphatase, receptor type, R
RGD ID: 620780
Description: Predicted to enable protein kinase binding activity and protein tyrosine phosphatase activity. Involved in neuron differentiation. Predicted to be active in cell junction; cytosol; and plasma membrane. Orthologous to human PTPRR (protein tyrosine phosphatase receptor type R); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: PC12-PTP1; Pcptp1; protein tyrosine phosphatase PCPTP1; protein-tyrosine phosphatase PCPTP1; R-PTP-R; receptor-type tyrosine-protein phosphatase R; tyrosine phosphatase CBPTP
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Note: There is an assembly problem in the Rnor_6.0 reference genome assembly, and therefore, annotation of this gene is split across NW_007905857.1 and NW_007905858.1 in NCBI's Rattus norvegicus Annotation Release 105. [17 Jun 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8753,548,611 - 53,815,632 (+)NCBIGRCr8
mRatBN7.2751,662,595 - 51,929,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl751,662,595 - 51,929,603 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx753,569,319 - 53,836,323 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0755,772,411 - 56,039,410 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0755,550,399 - 55,817,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0759,039,717 - 59,325,925 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,039,720 - 59,325,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,041,711 - 59,084,462 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0759,207,155 - 59,335,376 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4755,324,246 - 55,612,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1755,344,975 - 55,633,672 (+)NCBI
Celera748,446,749 - 48,710,763 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell junction  (IBA,IEA,ISO)
cytosol  (IBA,IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Interaction between chicken protein tyrosine phosphatase 1 (CPTP1)-like rat protein phosphatase 1 (PTP1) and p60(v-src) in v-src-transformed Rat-1 fibroblasts. Jung EJ and Kim CW, Exp Mol Med. 2002 Dec 31;34(6):476-80.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. A neuronal protein tyrosine phosphatase induced by nerve growth factor. Sharma E and Lombroso PJ, J Biol Chem 1995 Jan 6;270(1):49-53.
9. Cloning and expression of PCPTP1 encoding protein tyrosine phosphatase. Shiozuka K, etal., Gene 1995 Sep 11;162(2):279-84.
Additional References at PubMed
PMID:7832766   PMID:10601328   PMID:12477932   PMID:21724833   PMID:22664934  


Genomics

Comparative Map Data
Ptprr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8753,548,611 - 53,815,632 (+)NCBIGRCr8
mRatBN7.2751,662,595 - 51,929,605 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl751,662,595 - 51,929,603 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx753,569,319 - 53,836,323 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0755,772,411 - 56,039,410 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0755,550,399 - 55,817,402 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0759,039,717 - 59,325,925 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl759,039,720 - 59,325,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0759,041,711 - 59,084,462 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0759,207,155 - 59,335,376 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4755,324,246 - 55,612,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1755,344,975 - 55,633,672 (+)NCBI
Celera748,446,749 - 48,710,763 (+)NCBICelera
Cytogenetic Map7q22NCBI
PTPRR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381270,638,073 - 70,920,738 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1270,638,073 - 70,920,738 (-)EnsemblGRCh38hg38GRCh38
GRCh371271,031,853 - 71,314,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361269,318,129 - 69,600,853 (-)NCBINCBI36Build 36hg18NCBI36
Build 341269,318,128 - 69,434,632NCBI
Celera1270,695,535 - 70,977,822 (-)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1268,081,248 - 68,364,028 (-)NCBIHuRef
CHM1_11271,001,121 - 71,283,977 (-)NCBICHM1_1
T2T-CHM13v2.01270,617,477 - 70,900,236 (-)NCBIT2T-CHM13v2.0
Ptprr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910115,854,093 - 116,110,837 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10115,854,118 - 116,110,837 (+)EnsemblGRCm39 Ensembl
GRCm3810116,018,188 - 116,274,932 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10116,018,213 - 116,274,932 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710115,455,419 - 115,711,985 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610115,422,509 - 115,679,039 (+)NCBIMGSCv36mm8
Celera10117,959,423 - 118,215,461 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1064.01NCBI
Ptprr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540510,767,507 - 11,026,914 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540510,767,548 - 11,133,695 (-)NCBIChiLan1.0ChiLan1.0
PTPRR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21078,653,652 - 78,936,078 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11278,650,051 - 78,932,477 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01268,148,200 - 68,430,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11270,915,951 - 71,197,146 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1270,915,951 - 71,196,732 (-)Ensemblpanpan1.1panPan2
PTPRR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11012,385,121 - 12,618,438 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1012,385,107 - 12,594,004 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1012,324,091 - 12,557,686 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01012,517,368 - 12,751,240 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1012,517,368 - 12,751,216 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11012,382,959 - 12,616,783 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01012,630,054 - 12,863,956 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01012,754,267 - 12,988,172 (-)NCBIUU_Cfam_GSD_1.0
Ptprr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494545,732,053 - 45,841,891 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365458,268,218 - 8,377,169 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365458,268,227 - 8,377,427 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl534,794,977 - 35,047,818 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1534,794,970 - 35,048,550 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2537,346,846 - 37,511,950 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11166,222,495 - 66,496,247 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1166,223,605 - 66,353,700 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037179,171,480 - 179,454,986 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475026,906,871 - 27,188,249 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475026,907,292 - 27,188,129 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptprr
1099 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:642
Count of miRNA genes:276
Interacting mature miRNAs:359
Transcripts:ENSRNOT00000006401
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74659007091590070Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74725178365728867Rat
2293696Bmd32Bone mineral density QTL 325.10.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)74765143992651439Rat
2293707Bss32Bone structure and strength QTL 327.640.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)74765143992651439Rat
2300178Bmd54Bone mineral density QTL 545.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)74765143992651439Rat
2293644Bmd29Bone mineral density QTL 295.40.0001femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)74765143992651439Rat
2293667Bss42Bone structure and strength QTL 427.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)74765143992651439Rat
2293678Bss24Bone structure and strength QTL 246.710.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)74765143992651439Rat
2293685Bmd21Bone mineral density QTL 214.20.0003femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)74765143992651439Rat

Markers in Region
D7Got237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2751,685,053 - 51,685,209 (+)MAPPERmRatBN7.2
Rnor_6.0759,060,586 - 59,060,741NCBIRnor6.0
Rnor_5.0759,063,595 - 59,063,750UniSTSRnor5.0
RGSC_v3.4755,364,167 - 55,364,322UniSTSRGSC3.4
Celera748,468,205 - 48,468,360UniSTS
Cytogenetic Map7q22UniSTS
RH131513  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2751,929,395 - 51,929,575 (+)MAPPERmRatBN7.2
Rnor_6.0759,325,716 - 59,325,895NCBIRnor6.0
Rnor_5.0759,335,167 - 59,335,346UniSTSRnor5.0
RGSC_v3.4755,612,736 - 55,612,915UniSTSRGSC3.4
Celera748,710,554 - 48,710,733UniSTS
RH 3.4 Map7476.0UniSTS
Cytogenetic Map7q22UniSTS
AU048245  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2751,781,357 - 51,781,526 (+)MAPPERmRatBN7.2
Rnor_6.0762,386,196 - 62,386,364NCBIRnor6.0
Rnor_5.0762,372,783 - 62,372,951UniSTSRnor5.0
RGSC_v3.4755,461,824 - 55,461,992UniSTSRGSC3.4
Celera748,564,539 - 48,564,707UniSTS
Cytogenetic Map7q22UniSTS
D7Uwm24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2751,685,029 - 51,685,285 (+)MAPPERmRatBN7.2
Rnor_6.0759,060,562 - 59,060,817NCBIRnor6.0
Rnor_5.0759,063,571 - 59,063,826UniSTSRnor5.0
Celera748,468,181 - 48,468,436UniSTS
Cytogenetic Map7q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 4 44 1 1
Low 2 19 15 4 4 4 6 7 28 35 28 10 6
Below cutoff 20 40 35 15 35 2 4 2 12 2

Sequence


RefSeq Acc Id: ENSRNOT00000006401   ⟹   ENSRNOP00000006401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl751,662,595 - 51,929,602 (+)Ensembl
Rnor_6.0 Ensembl759,039,720 - 59,325,947 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085073   ⟹   ENSRNOP00000070648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl751,800,156 - 51,929,603 (+)Ensembl
Rnor_6.0 Ensembl759,200,918 - 59,325,922 (+)Ensembl
RefSeq Acc Id: NM_001113390   ⟹   NP_001106861
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8753,686,239 - 53,815,632 (+)NCBI
mRatBN7.2751,800,199 - 51,929,605 (+)NCBI
Rnor_6.0759,200,941 - 59,325,925 (+)NCBI
Rnor_5.0759,207,155 - 59,335,376 (+)NCBI
RGSC_v3.4755,324,246 - 55,612,945 (+)RGD
Celera748,583,357 - 48,710,763 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053594   ⟹   NP_446046
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8753,548,642 - 53,815,632 (+)NCBI
mRatBN7.2751,662,595 - 51,929,605 (+)NCBI
Rnor_6.0759,039,717 - 59,325,925 (+)NCBI
Rnor_5.0759,041,711 - 59,084,462 (+)NCBI
Rnor_5.0759,207,155 - 59,335,376 (+)NCBI
RGSC_v3.4755,324,246 - 55,612,945 (+)RGD
Celera748,446,749 - 48,710,763 (+)RGD
Sequence:
RefSeq Acc Id: XM_063264355   ⟹   XP_063120425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8753,548,611 - 53,815,632 (+)NCBI
RefSeq Acc Id: NP_446046   ⟸   NM_053594
- Peptide Label: isoform 1 precursor
- UniProtKB: Q63419 (UniProtKB/Swiss-Prot),   Q62695 (UniProtKB/Swiss-Prot),   O08617 (UniProtKB/Swiss-Prot),   G3V6L5 (UniProtKB/TrEMBL),   A6IGM0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106861   ⟸   NM_001113390
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JYG7 (UniProtKB/TrEMBL),   A6IGM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006401   ⟸   ENSRNOT00000006401
RefSeq Acc Id: ENSRNOP00000070648   ⟸   ENSRNOT00000085073
RefSeq Acc Id: XP_063120425   ⟸   XM_063264355
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08617-F1-model_v2 AlphaFold O08617 1-656 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695204
Promoter ID:EPDNEW_R5726
Type:multiple initiation site
Name:Ptprr_1
Description:protein tyrosine phosphatase, receptor type, R
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0759,039,813 - 59,039,873EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620780 AgrOrtholog
BioCyc Gene G2FUF-34044 BioCyc
Ensembl Genes ENSRNOG00000004483 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006401 ENTREZGENE
  ENSRNOT00000006401.5 UniProtKB/TrEMBL
  ENSRNOT00000085073 ENTREZGENE
  ENSRNOT00000085073.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7315399 IMAGE-MGC_LOAD
InterPro Prot-tyrosine_phosphatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPase_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_KIM-con UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_Pase_rcpt_R/non-rcpt_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94202 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105367 IMAGE-MGC_LOAD
NCBI Gene 94202 ENTREZGENE
PANTHER PTHR46198 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptprr PhenoGen
PIRSF PTPRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS KIMPTPASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004483 RatGTEx
SMART PTPc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTPc_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JYG7 ENTREZGENE, UniProtKB/TrEMBL
  A6IGM0 ENTREZGENE, UniProtKB/TrEMBL
  A6IGM2 ENTREZGENE, UniProtKB/TrEMBL
  A6IGM3_RAT UniProtKB/TrEMBL
  A6IGM4_RAT UniProtKB/TrEMBL
  G3V6L5 ENTREZGENE, UniProtKB/TrEMBL
  O08617 ENTREZGENE, UniProtKB/Swiss-Prot
  Q5FWV8_RAT UniProtKB/TrEMBL
  Q62695 ENTREZGENE
  Q63419 ENTREZGENE
UniProt Secondary Q62695 UniProtKB/Swiss-Prot
  Q63419 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ptprr  protein tyrosine phosphatase, receptor type, R      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ptprr  protein tyrosine phosphatase, receptor type, R      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation mRNA expression of the 3.0 kb transcript is induced by nerve growth factor 729713
gene_transcript contains 1.5, 2.6, and 3.0 kb mRNA transcripts 729713