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Gene: Slc17a8 (solute carrier family 17 member 8) Rattus norvegicus
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Symbol: Slc17a8
Name: solute carrier family 17 member 8
Description: Predicted to have L-glutamate transmembrane transporter activity. Involved in brain development; cochlea development; and neural retina development. Localizes to several cellular components, including the glial limiting end-foot; neuron projection; and perikaryon. Biomarker of cochlear disease; sciatic neuropathy; transient cerebral ischemia; and trichinosis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Orthologous to human SLC17A8 (solute carrier family 17 member 8); PARTICIPATES IN auditory mechanotransduction pathway; glutamate signaling pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; solute carrier family 17 (vesicular glutamate transporter), member 8; vesicular glutamate transporter 3; Vglut3
Orthologs:
Homo sapiens (human) : SLC17A8 (solute carrier family 17 member 8)  HGNC  Alliance
Mus musculus (house mouse) : Slc17a8 (solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc17a8 (solute carrier family 17 member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC17A8 (solute carrier family 17 member 8)
Canis lupus familiaris (dog) : SLC17A8 (solute carrier family 17 member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc17a8 (solute carrier family 17 member 8)
Sus scrofa (pig) : SLC17A8 (solute carrier family 17 member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0730,215,231 - 30,274,993 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0730,314,804 - 30,371,888 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,361,488 - 26,413,820 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1726,381,758 - 26,434,091 (-)NCBI
Celera721,139,735 - 21,191,778 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc17a8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628870
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.