Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc17a8
Name: solute carrier family 17 member 8
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc17a8affects methylationISOSLC17A8 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of SLC17A8 promoterPMID:27901495
Slc17a8decreases expressionISOSlc17a8 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of SLC17A8 mRNAPMID:32417428
Slc17a8decreases methylationISOSLC17A8 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of SLC17A8 3' UTRPMID:27901495
Slc17a8increases expressionISOSlc17a8 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased expression of SLC17A8 mRNAPMID:27195522
Slc17a8increases methylationISOSlc17a8 (Mus musculus)6480464CTDBenzo(a)pyrene results in increased methylation of SLC17A8 exon; Benzo(a)pyrene results in increased methylation of SLC17A8 intronPMID:27901495
Slc17a8increases methylationISOSLC17A8 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of SLC17A8 exonPMID:27901495
Go Back to source page   Continue to Ontology report