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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628870
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc17a8
Name: solute carrier family 17 member 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc17a8decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC17A8 mRNAPMID:32109520
Slc17a8multiple interactionsISOSlc17a8 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of SLC17A8 mRNAPMID:25975270
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