Slc25a3 (solute carrier family 25 member 3) - Rat Genome Database

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Gene: Slc25a3 (solute carrier family 25 member 3) Rattus norvegicus
Analyze
Symbol: Slc25a3 (Ensembl: Tmpo)
Name: solute carrier family 25 member 3 (Ensembl:thymopoietin)
RGD ID: 70986
Description: Predicted to enable phosphate transmembrane transporter activity and phosphate:proton symporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Orthologous to human SLC25A3 (solute carrier family 25 member 3); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2,2-tetramine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: adenine nucleotide translocator), member 3; Phc; phosphate carrier mitochondrial; phosphate carrier protein, mitochondrial; phosphate transport protein; PTP; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 3; solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8727,499,164 - 27,506,685 (-)NCBIGRCr8
mRatBN7.2725,611,937 - 25,619,401 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl725,586,725 - 25,667,727 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx727,606,380 - 27,613,843 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0729,768,761 - 29,776,224 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0729,546,169 - 29,553,632 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0731,816,601 - 31,824,064 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl731,816,602 - 31,824,071 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0731,904,033 - 31,911,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4728,054,665 - 28,061,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1728,074,935 - 28,082,074 (-)NCBI
Celera722,738,470 - 22,745,931 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
biochanin A  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
chlordecone  (ISO)
clobetasol  (ISO)
clofibrate  (EXP)
corosolic acid  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
GW 4064  (ISO)
haloperidol  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
lamivudine  (ISO)
menadione  (ISO)
miconazole  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
ochratoxin A  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
pirinixic acid  (EXP)
rac-lactic acid  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
streptozocin  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Energy-linked anion transport. Cloning, sequencing, and characterization of a full length cDNA encoding the rat liver mitochondrial proton/phosphate symporter. Ferreira GC, etal., J Biol Chem 1989 Sep 15;264(26):15628-33.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Gene Data Set MGD Curation, June 12, 2002
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1985946   PMID:2250020   PMID:12477932   PMID:12865426   PMID:14651853   PMID:17634366   PMID:18614015   PMID:19056867   PMID:19946888   PMID:21265734   PMID:22082260   PMID:23063677  
PMID:23209302   PMID:23376485   PMID:24625528   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Slc25a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8727,499,164 - 27,506,685 (-)NCBIGRCr8
mRatBN7.2725,611,937 - 25,619,401 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl725,586,725 - 25,667,727 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx727,606,380 - 27,613,843 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0729,768,761 - 29,776,224 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0729,546,169 - 29,553,632 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0731,816,601 - 31,824,064 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl731,816,602 - 31,824,071 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0731,904,033 - 31,911,496 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4728,054,665 - 28,061,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1728,074,935 - 28,082,074 (-)NCBI
Celera722,738,470 - 22,745,931 (-)NCBICelera
Cytogenetic Map7q13NCBI
SLC25A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381298,593,686 - 98,606,367 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1298,593,591 - 98,606,379 (+)EnsemblGRCh38hg38GRCh38
GRCh371298,987,464 - 99,000,145 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361297,511,534 - 97,519,909 (+)NCBINCBI36Build 36hg18NCBI36
Build 341297,489,870 - 97,498,245NCBI
Celera1298,652,117 - 98,660,491 (+)NCBICelera
Cytogenetic Map12q23.1NCBI
HuRef1296,048,552 - 96,056,927 (+)NCBIHuRef
CHM1_11298,952,393 - 98,960,768 (+)NCBICHM1_1
T2T-CHM13v2.01298,566,653 - 98,579,332 (+)NCBIT2T-CHM13v2.0
Slc25a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391090,952,436 - 90,959,902 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1090,952,436 - 90,959,921 (-)EnsemblGRCm39 Ensembl
GRCm381091,116,574 - 91,124,046 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1091,116,574 - 91,124,059 (-)EnsemblGRCm38mm10GRCm38
MGSCv371090,579,323 - 90,586,708 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361090,546,377 - 90,553,762 (-)NCBIMGSCv36mm8
Celera1093,110,864 - 93,118,246 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1045.6NCBI
Slc25a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540534,585,004 - 34,591,289 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540534,584,676 - 34,591,470 (+)NCBIChiLan1.0ChiLan1.0
SLC25A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210106,656,978 - 106,665,026 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112106,653,391 - 106,661,415 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01296,173,350 - 96,181,400 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11299,588,949 - 99,597,027 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1299,588,949 - 99,597,027 (+)Ensemblpanpan1.1panPan2
SLC25A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11537,992,509 - 37,999,127 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1537,992,649 - 37,999,125 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1538,374,229 - 38,380,848 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01538,655,938 - 38,662,556 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1538,656,053 - 38,662,554 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11537,927,813 - 37,934,433 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01538,020,496 - 38,027,114 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01538,294,180 - 38,300,798 (+)NCBIUU_Cfam_GSD_1.0
Slc25a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494521,923,195 - 21,930,497 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649214,933,609 - 14,941,193 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649214,933,609 - 14,940,884 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl585,284,311 - 85,292,328 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1585,284,405 - 85,292,336 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2589,607,539 - 89,614,924 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11193,892,253 - 93,899,934 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1193,892,630 - 93,899,754 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037151,167,502 - 151,175,198 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247508,972,806 - 8,979,442 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247508,972,806 - 8,979,464 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a3
40 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:122
Count of miRNA genes:101
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000011494
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat

Markers in Region
RH130792  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2725,611,947 - 25,612,165 (+)MAPPERmRatBN7.2
Rnor_6.0731,816,612 - 31,816,829NCBIRnor6.0
Rnor_5.0731,904,044 - 31,904,261UniSTSRnor5.0
RGSC_v3.4728,054,667 - 28,054,884UniSTSRGSC3.4
Celera722,738,481 - 22,738,698UniSTS
RH 3.4 Map7153.3UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB577607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000011494   ⟹   ENSRNOP00000011494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl731,816,602 - 31,824,064 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080824   ⟹   ENSRNOP00000070805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl731,816,606 - 31,824,071 (-)Ensembl
RefSeq Acc Id: NM_001270788   ⟹   NP_001257717
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8727,499,164 - 27,506,627 (-)NCBI
mRatBN7.2725,611,937 - 25,619,401 (-)NCBI
Rnor_6.0731,816,601 - 31,824,064 (-)NCBI
Rnor_5.0731,904,033 - 31,911,496 (-)NCBI
Celera722,738,470 - 22,745,931 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139100   ⟹   NP_620800
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8727,499,164 - 27,506,627 (-)NCBI
mRatBN7.2725,611,937 - 25,619,401 (-)NCBI
Rnor_6.0731,816,601 - 31,824,064 (-)NCBI
Rnor_5.0731,904,033 - 31,911,496 (-)NCBI
RGSC_v3.4728,054,665 - 28,061,801 (-)RGD
Celera722,738,470 - 22,745,931 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063262985   ⟹   XP_063119055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8727,499,164 - 27,506,685 (-)NCBI
RefSeq Acc Id: XM_063262986   ⟹   XP_063119056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8727,499,164 - 27,506,685 (-)NCBI
RefSeq Acc Id: NP_620800   ⟸   NM_139100
- Peptide Label: isoform 2 precursor
- UniProtKB: G3V741 (UniProtKB/TrEMBL),   A6IFV1 (UniProtKB/TrEMBL),   A0A8I6GJ63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257717   ⟸   NM_001270788
- Peptide Label: isoform 1
- UniProtKB: Q6IRH6 (UniProtKB/TrEMBL),   A6IFV2 (UniProtKB/TrEMBL),   A0A8I6GJ63 (UniProtKB/TrEMBL),   A0A0G2JYV5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070805   ⟸   ENSRNOT00000080824
Ensembl Acc Id: ENSRNOP00000011494   ⟸   ENSRNOT00000011494
RefSeq Acc Id: XP_063119056   ⟸   XM_063262986
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GJ63 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119055   ⟸   XM_063262985
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GJ63 (UniProtKB/TrEMBL)
Protein Domains
LEM   LEM-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16036-F1-model_v2 AlphaFold P16036 1-356 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695141
Promoter ID:EPDNEW_R5666
Type:multiple initiation site
Name:Slc25a3_1
Description:solute carrier family 25 member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0731,824,018 - 31,824,078EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70986 AgrOrtholog
BioCyc Gene G2FUF-34467 BioCyc
Ensembl Genes ENSRNOG00000008289 Ensembl
  ENSRNOG00000008797 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011494.5 UniProtKB/TrEMBL
  ENSRNOT00000080824.2 UniProtKB/TrEMBL
  ENSRNOT00000113184.1 UniProtKB/TrEMBL
  ENSRNOT00000113551.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.40 UniProtKB/TrEMBL
  1.50.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104964 IMAGE-MGC_LOAD
InterPro LEM-like_dom UniProtKB/TrEMBL
  LEM/LEM-like_dom_sf UniProtKB/TrEMBL
  LEM_dom UniProtKB/TrEMBL
  LEM_domain UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pic2/Mir1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:245959 UniProtKB/TrEMBL
MGC_CLONE MGC:91476 IMAGE-MGC_LOAD
NCBI Gene 245959 ENTREZGENE
PANTHER LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORM BETA UniProtKB/TrEMBL
  LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN UniProtKB/TrEMBL
  PHOSPHATE CARRIER PROTEIN, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45671 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LEM UniProtKB/TrEMBL
  Mito_carr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thymopoietin UniProtKB/TrEMBL
PhenoGen Slc25a3 PhenoGen
PROSITE LEM UniProtKB/TrEMBL
  LEM_LIKE UniProtKB/TrEMBL
  SOLCAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008289 RatGTEx
  ENSRNOG00000008797 RatGTEx
SMART LEM UniProtKB/TrEMBL
  Thymopoietin UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63451 UniProtKB/TrEMBL
UniProt A0A0G2JYV5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GF99_RAT UniProtKB/TrEMBL
  A0A8I6GJ63 ENTREZGENE, UniProtKB/TrEMBL
  A6IFV1 ENTREZGENE, UniProtKB/TrEMBL
  A6IFV2 ENTREZGENE, UniProtKB/TrEMBL
  A6IFV3_RAT UniProtKB/TrEMBL
  A6IFV4_RAT UniProtKB/TrEMBL
  A6IFV5_RAT UniProtKB/TrEMBL
  G3V741 ENTREZGENE, UniProtKB/TrEMBL
  MPCP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6IRH6 ENTREZGENE
UniProt Secondary Q6IRH6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc25a3  solute carrier family 25 member 3  Slc25a3  solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Slc25a3  solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3  Slc25a3  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Slc25a3  solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 3      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein 312 amino acids 70617