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Gene: Brd4 (bromodomain containing 4) Rattus norvegicus
Symbol: Brd4
Name: bromodomain containing 4
RGD ID: 1307282
Description: Predicted to have several functions, including P-TEFb complex binding activity; lysine-acetylated histone binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including chromatin organization; positive regulation of cell cycle; and regulation of transcription, DNA-templated. Predicted to localize to condensed nuclear chromosome; cyclin/CDK positive transcription elongation factor complex; and nuclear chromatin. Human ortholog(s) of this gene implicated in colon cancer and idiopathic pulmonary fibrosis. Orthologous to human BRD4 (bromodomain containing 4); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bromodomain-containing protein 4; LOC362844
Homo sapiens (human) : BRD4 (bromodomain containing 4)  HGNC  Alliance
Mus musculus (house mouse) : Brd4 (bromodomain containing 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brd4 (bromodomain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : BRD4 (bromodomain containing 4)
Canis lupus familiaris (dog) : BRD4 (bromodomain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brd4 (bromodomain containing 4)
Sus scrofa (pig) : BRD4 (bromodomain containing 4)
Chlorocebus sabaeus (African green monkey) : BRD4 (bromodomain containing 4)
Heterocephalus glaber (naked mole-rat) : Brd4 (bromodomain containing 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0714,222,101 - 14,303,055 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl714,222,101 - 14,303,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,378,187 - 14,457,537 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,772,428 - 12,853,406 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1712,774,215 - 12,853,571 (-)NCBI
Celera79,328,703 - 9,362,558 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Brd4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307282
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.