Brd4 Rat 1,2-dimethylhydrazine increases expression ISO Brd4 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of BRD4 mRNA CTD PMID:22206623 Brd4 Rat 10H-phenothiazine multiple interactions ISO BRD4 (Homo sapiens) 6480464 phenothiazine inhibits the reaction [BRD4 protein binds to MED1 protein] CTD PMID:26735014 Brd4 Rat 17beta-hydroxy-5alpha-androstan-3-one affects localization ISO BRD4 (Homo sapiens) 6480464 Dihydrotestosterone affects the localization of BRD4 protein CTD PMID:24759320 Brd4 Rat 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO BRD4 (Homo sapiens) 6480464 (+)-JQ1 compound inhibits the reaction [Dihydrotestosterone affects the localization of BRD4 protein] CTD PMID:24759320 Brd4 Rat 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of BRD4 mRNA CTD PMID:27291303 Brd4 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Brd4 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of BRD4 mRNA CTD PMID:21570461|PMID:24680724 Brd4 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Brd4 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of BRD4 mRNA CTD PMID:37318321 Brd4 Rat 3,4-methylenedioxymethamphetamine increases expression ISO Brd4 (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BRD4 mRNA CTD PMID:20188158 Brd4 Rat 4,4'-diaminodiphenylmethane increases expression ISO Brd4 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of BRD4 mRNA CTD PMID:18648102 Brd4 Rat 4,4'-sulfonyldiphenol decreases expression ISO Brd4 (Mus musculus) 6480464 bisphenol S results in decreased expression of BRD4 mRNA CTD PMID:39298647 Brd4 Rat 4,5,6,7-TETRABROMOBENZOTRIAZOLE multiple interactions ISO Brd4 (Mus musculus) 6480464 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to ARC promoter]]; more ... CTD PMID:26301327 Brd4 Rat 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO BRD4 (Homo sapiens) 6480464 BRD4 mutant form inhibits the reaction [6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [lipopolysaccharide, E coli O55-B5 results more ... CTD PMID:26212199 Brd4 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of BRD4 mRNA CTD PMID:24780913 Brd4 Rat acetazolamide increases expression ISO Brd4 (Mus musculus) 6480464 Acetazolamide results in increased expression of BRD4 mRNA CTD PMID:19274763 Brd4 Rat acetylsalicylic acid increases expression ISO BRD4 (Homo sapiens) 6480464 Aspirin results in increased expression of BRD4 mRNA CTD PMID:11906190 Brd4 Rat aflatoxin B1 increases methylation ISO BRD4 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of BRD4 intron CTD PMID:30157460 Brd4 Rat Aflatoxin B2 alpha increases methylation ISO BRD4 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of BRD4 intron CTD PMID:30157460 Brd4 Rat ARV-825 multiple interactions ISO BRD4 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein]; carfilzomib inhibits more ... CTD PMID:26051217 Brd4 Rat ARV-825 increases degradation ISO BRD4 (Homo sapiens) 6480464 ARV-825 results in increased degradation of BRD4 protein CTD PMID:26051217 Brd4 Rat atrazine increases expression ISO BRD4 (Homo sapiens) 6480464 Atrazine results in increased expression of BRD4 mRNA CTD PMID:22378314 Brd4 Rat bellidifolin multiple interactions ISO Brd4 (Mus musculus) 6480464 bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 mRNA]; bellidifolin inhibits the more ... CTD PMID:37528096 Brd4 Rat benzo[a]pyrene increases expression ISO Brd4 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of BRD4 mRNA CTD PMID:22228805 Brd4 Rat benzo[a]pyrene decreases methylation ISO BRD4 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of BRD4 5' UTR; Benzo(a)pyrene results in decreased methylation of more ... CTD PMID:27901495 Brd4 Rat benzo[a]pyrene affects methylation ISO BRD4 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of BRD4 promoter CTD PMID:27901495 Brd4 Rat beta-naphthoflavone decreases expression ISO BRD4 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of BRD4 protein CTD PMID:39638853 Brd4 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of BRD4 mRNA CTD PMID:25181051 Brd4 Rat bisphenol A decreases expression ISO BRD4 (Homo sapiens) 6480464 bisphenol A results in decreased expression of BRD4 protein CTD PMID:37567409 Brd4 Rat bisphenol A increases methylation ISO BRD4 (Homo sapiens) 6480464 bisphenol A results in increased methylation of BRD4 gene CTD PMID:31601247 Brd4 Rat bisphenol A decreases expression ISO Brd4 (Mus musculus) 6480464 bisphenol A results in decreased expression of BRD4 mRNA CTD PMID:33221593 Brd4 Rat bisphenol F increases expression ISO BRD4 (Homo sapiens) 6480464 bisphenol F results in increased expression of BRD4 mRNA CTD PMID:38568856 Brd4 Rat bisphenol F multiple interactions ISO BRD4 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of BRD4 gene CTD PMID:31601247 Brd4 Rat buta-1,3-diene decreases expression ISO Brd4 (Mus musculus) 6480464 1,3-butadiene results in decreased expression of BRD4 mRNA CTD PMID:29038090 Brd4 Rat cadmium atom multiple interactions ISO BRD4 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BRD4 more ... CTD PMID:35301059 Brd4 Rat cadmium dichloride multiple interactions ISO BRD4 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BRD4 more ... CTD PMID:35301059 Brd4 Rat caffeine decreases phosphorylation ISO BRD4 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of BRD4 protein CTD PMID:35688186 Brd4 Rat carfilzomib multiple interactions ISO BRD4 (Homo sapiens) 6480464 carfilzomib inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein] CTD PMID:26051217 Brd4 Rat ceruletide multiple interactions ISO Brd4 (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased more ... CTD PMID:26390243 Brd4 Rat chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of BRD4 mRNA CTD PMID:23125180 Brd4 Rat cisplatin decreases expression ISO BRD4 (Homo sapiens) 6480464 Cisplatin results in decreased expression of BRD4 mRNA CTD PMID:27392435|PMID:27594783 Brd4 Rat cocaine multiple interactions ISO Brd4 (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; more ... CTD PMID:26558777 Brd4 Rat cocaine increases expression ISO Brd4 (Mus musculus) 6480464 Cocaine results in increased expression of BRD4 protein CTD PMID:26558777 Brd4 Rat cocaine increases expression EXP 6480464 Cocaine results in increased expression of BRD4 protein CTD PMID:26558777 Brd4 Rat coumarin decreases phosphorylation ISO BRD4 (Homo sapiens) 6480464 coumarin results in decreased phosphorylation of BRD4 protein CTD PMID:35688186 Brd4 Rat cyclosporin A increases expression ISO BRD4 (Homo sapiens) 6480464 Cyclosporine results in increased expression of BRD4 mRNA CTD PMID:25562108 Brd4 Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of BRD4 mRNA CTD PMID:23640034 Brd4 Rat dibenzo[a,l]pyrene increases expression ISO Brd4 (Mus musculus) 6480464 dibenzo(a,l)pyrene results in increased expression of BRD4 mRNA CTD PMID:25908611 Brd4 Rat Dibutyl phosphate affects expression ISO BRD4 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of BRD4 mRNA CTD PMID:37042841 Brd4 Rat dicrotophos increases expression ISO BRD4 (Homo sapiens) 6480464 dicrotophos results in increased expression of BRD4 mRNA CTD PMID:28302478 Brd4 Rat dioxygen increases expression ISO Brd4 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of BRD4 mRNA CTD PMID:24205000 Brd4 Rat dioxygen increases expression ISO BRD4 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of BRD4 CTD PMID:27292261 Brd4 Rat dioxygen multiple interactions ISO BRD4 (Homo sapiens) 6480464 Oxygen deficiency promotes the reaction [BRD4 protein binds to CA9 promoter]; Oxygen deficiency promotes the more ... CTD PMID:27292261 Brd4 Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of BRD4 mRNA CTD PMID:25152437 Brd4 Rat dorsomorphin multiple interactions ISO BRD4 (Homo sapiens) 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Brd4 Rat doxorubicin decreases expression ISO BRD4 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of BRD4 mRNA CTD PMID:29803840 Brd4 Rat enzyme inhibitor multiple interactions ISO BRD4 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ... CTD PMID:23301498 Brd4 Rat ethanol affects splicing ISO Brd4 (Mus musculus) 6480464 Ethanol affects the splicing of BRD4 mRNA CTD PMID:30319688 Brd4 Rat everolimus multiple interactions ISO BRD4 (Homo sapiens) 6480464 [MYC protein results in decreased susceptibility to Everolimus] promotes the reaction [BRD4 protein binds to more ... CTD PMID:25537515 Brd4 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of BRD4 mRNA CTD PMID:20566332 Brd4 Rat folic acid decreases expression ISO BRD4 (Homo sapiens) 6480464 Folic Acid results in decreased expression of BRD4 mRNA CTD PMID:21867686 Brd4 Rat fulvestrant multiple interactions ISO BRD4 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of BRD4 gene CTD PMID:31601247 Brd4 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of BRD4 mRNA CTD PMID:22061828 Brd4 Rat glyphosate increases expression EXP 6480464 Glyphosate results in increased expression of BRD4 mRNA CTD PMID:26302742 Brd4 Rat glyphosate increases methylation EXP 6480464 Glyphosate results in increased methylation of BRD4 gene CTD PMID:31011160 Brd4 Rat GSK-J4 increases expression ISO BRD4 (Homo sapiens) 6480464 GSK-J4 results in increased expression of BRD4 mRNA CTD PMID:29301935 Brd4 Rat hydrogen peroxide multiple interactions ISO BRD4 (Homo sapiens) 6480464 (+)-JQ1 compound inhibits the reaction [[Hydrogen Peroxide co-treated with IL1B protein] promotes the reaction [BRD4 more ... CTD PMID:24759736|PMID:33094643 Brd4 Rat hydrogen peroxide increases expression ISO BRD4 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of BRD4 mRNA; Hydrogen Peroxide results in increased expression more ... CTD PMID:33094643 Brd4 Rat hypochlorous acid decreases expression ISO Brd4 (Mus musculus) 6480464 Hypochlorous Acid results in decreased expression of BRD4 mRNA CTD PMID:19376150 Brd4 Rat immunological adjuvant increases expression ISO Brd4 (Mus musculus) 6480464 Adjuvants, Immunologic results in increased expression of BRD4 mRNA CTD PMID:25656449 Brd4 Rat inulin multiple interactions ISO Brd4 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of BRD4 mRNA CTD PMID:36331819 Brd4 Rat isoprenaline decreases expression ISO Brd4 (Mus musculus) 6480464 Isoproterenol results in decreased expression of BRD4 mRNA CTD PMID:20003209 Brd4 Rat isoprenaline increases expression ISO Brd4 (Mus musculus) 6480464 Isoproterenol results in increased expression of BRD4 mRNA; Isoproterenol results in increased expression of BRD4 more ... CTD PMID:37528096 Brd4 Rat isoprenaline multiple interactions ISO Brd4 (Mus musculus) 6480464 bellidifolin inhibits the reaction [Isoproterenol results in increased expression of BRD4 mRNA]; bellidifolin inhibits the more ... CTD PMID:37528096 Brd4 Rat ivermectin decreases expression ISO BRD4 (Homo sapiens) 6480464 Ivermectin results in decreased expression of BRD4 protein CTD PMID:32959892 Brd4 Rat lead diacetate multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which results in increased expression of BRD4 more ... CTD PMID:39276841 Brd4 Rat lead(0) multiple interactions EXP 6480464 [lead acetate results in increased abundance of Lead] which results in increased expression of BRD4 more ... CTD PMID:39276841 Brd4 Rat leflunomide increases expression ISO BRD4 (Homo sapiens) 6480464 leflunomide results in increased expression of BRD4 mRNA CTD PMID:28988120 Brd4 Rat lipopolysaccharide multiple interactions ISO Brd4 (Mus musculus) 6480464 GSK1210151A inhibits the reaction [[Lipopolysaccharides results in increased acetylation of RELA protein] which binds to more ... CTD PMID:25778533 Brd4 Rat methylmercury chloride increases expression ISO BRD4 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of BRD4 mRNA CTD PMID:23179753|PMID:26272509 Brd4 Rat methylmercury chloride multiple interactions ISO BRD4 (Homo sapiens) 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Brd4 Rat methylparaben increases expression ISO BRD4 (Homo sapiens) 6480464 methylparaben results in increased expression of BRD4 mRNA CTD PMID:38568856 Brd4 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO BRD4 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde more ... CTD PMID:23686307|PMID:26051217 Brd4 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Brd4 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results more ... CTD PMID:25877301 Brd4 Rat ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of BRD4 mRNA CTD PMID:22124623 Brd4 Rat ochratoxin A decreases expression ISO BRD4 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of BRD4 protein CTD PMID:39638853 Brd4 Rat olaparib affects response to substance ISO BRD4 (Homo sapiens) 6480464 BRD4 protein affects the susceptibility to olaparib CTD PMID:29567272 Brd4 Rat olaparib multiple interactions ISO BRD4 (Homo sapiens) 6480464 [BRD4 protein affects the susceptibility to olaparib] which affects the cleavage of PARP1 protein; [BRD4 more ... CTD PMID:29567272 Brd4 Rat paracetamol decreases expression ISO BRD4 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of BRD4 mRNA CTD PMID:26690555 Brd4 Rat pentachlorophenol increases expression ISO Brd4 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of BRD4 mRNA CTD PMID:23892564 Brd4 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Brd4 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of BRD4 mRNA CTD PMID:36331819 Brd4 Rat perfluorooctanoic acid decreases expression ISO BRD4 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of BRD4 protein CTD PMID:26879310 Brd4 Rat phenylephrine multiple interactions EXP 6480464 Phenylephrine promotes the reaction [BRD4 protein binds to NPPA promoter] CTD PMID:23939492 Brd4 Rat phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of BRD4 protein CTD PMID:23939492 Brd4 Rat pirinixic acid increases expression ISO Brd4 (Mus musculus) 6480464 pirinixic acid results in increased expression of BRD4 mRNA CTD PMID:18445702 Brd4 Rat pomalidomide multiple interactions ISO BRD4 (Homo sapiens) 6480464 pomalidomide inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein] CTD PMID:26051217 Brd4 Rat rucaparib affects response to substance ISO BRD4 (Homo sapiens) 6480464 BRD4 protein affects the susceptibility to rucaparib CTD PMID:32927276 Brd4 Rat sanguinarine multiple interactions ISO BRD4 (Homo sapiens) 6480464 sanguinarine binds to and results in decreased activity of BRD4 protein CTD PMID:37393519 Brd4 Rat SB 431542 multiple interactions ISO BRD4 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of BRD4 more ... CTD PMID:27188386|PMID:37664457 Brd4 Rat sodium arsenite increases expression ISO BRD4 (Homo sapiens) 6480464 sodium arsenite results in increased expression of BRD4 mRNA CTD PMID:38568856 Brd4 Rat Soman increases expression EXP 6480464 Soman results in increased expression of BRD4 mRNA CTD PMID:19281266 Brd4 Rat sulindac decreases expression ISO BRD4 (Homo sapiens) 6480464 Sulindac results in decreased expression of BRD4 mRNA CTD PMID:11906190 Brd4 Rat sunitinib increases expression ISO BRD4 (Homo sapiens) 6480464 Sunitinib results in increased expression of BRD4 mRNA CTD PMID:31533062 Brd4 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of BRD4 mRNA CTD PMID:34492290 Brd4 Rat thiram increases expression ISO BRD4 (Homo sapiens) 6480464 Thiram results in increased expression of BRD4 mRNA CTD PMID:38568856 Brd4 Rat triphenyl phosphate affects expression ISO BRD4 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of BRD4 mRNA CTD PMID:37042841 Brd4 Rat triptonide affects expression ISO Brd4 (Mus musculus) 6480464 triptonide affects the expression of BRD4 mRNA CTD PMID:33045310 Brd4 Rat troglitazone decreases expression ISO Brd4 (Mus musculus) 6480464 troglitazone results in decreased expression of BRD4 mRNA CTD PMID:28973697 Brd4 Rat tungsten decreases expression ISO Brd4 (Mus musculus) 6480464 Tungsten results in decreased expression of BRD4 mRNA CTD PMID:30912803 Brd4 Rat urethane increases expression ISO BRD4 (Homo sapiens) 6480464 Urethane results in increased expression of BRD4 mRNA CTD PMID:28818685 Brd4 Rat valproic acid affects expression ISO Brd4 (Mus musculus) 6480464 Valproic Acid affects the expression of BRD4 mRNA CTD PMID:17292431 Brd4 Rat valproic acid increases expression ISO BRD4 (Homo sapiens) 6480464 Valproic Acid results in increased expression of BRD4 mRNA CTD PMID:23179753 Brd4 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of BRD4 mRNA CTD PMID:19015723 Brd4 Rat vorinostat decreases expression ISO BRD4 (Homo sapiens) 6480464 vorinostat results in decreased expression of BRD4 mRNA CTD PMID:27188386