1,2-dimethylhydrazine increases expression ISO RGD:1316386 6480464 1, 2-Dimethylhydrazine results in increased expression of BRD4 mRNA CTD PMID:22206623 10H-phenothiazine multiple interactions ISO RGD:1316385 6480464 phenothiazine inhibits the reaction [BRD4 protein binds to MED1 protein] CTD PMID:26735014 17beta-hydroxy-5alpha-androstan-3-one affects localization ISO RGD:1316385 6480464 Dihydrotestosterone affects the localization of BRD4 protein CTD PMID:24759320 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:1316385 6480464 (+)-JQ1 compound inhibits the reaction [Dihydrotestosterone affects the localization of BRD4 protein] CTD PMID:24759320 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1316386 6480464 Tetrachlorodibenzodioxin affects the expression of BRD4 mRNA CTD PMID:21570461 , PMID:24680724 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1316386 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of BRD4 mRNA CTD PMID:20188158 4,4'-diaminodiphenylmethane increases expression ISO RGD:1316386 6480464 4, 4'-diaminodiphenylmethane results in increased expression of BRD4 mRNA CTD PMID:18648102 4,5,6,7-TETRABROMOBENZOTRIAZOLE multiple interactions ISO RGD:1316386 6480464 4 more ... CTD PMID:26301327 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:1316385 6480464 BRD4 mutant form inhibits the reaction [6-chloro-2 more ... CTD PMID:26212199 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of BRD4 mRNA CTD PMID:24780913 acetazolamide increases expression ISO RGD:1316386 6480464 Acetazolamide results in increased expression of BRD4 mRNA CTD PMID:19274763 acetylsalicylic acid increases expression ISO RGD:1316385 6480464 Aspirin results in increased expression of BRD4 mRNA CTD PMID:11906190 aflatoxin B1 increases methylation ISO RGD:1316385 6480464 Aflatoxin B1 results in increased methylation of BRD4 intron CTD PMID:30157460 Aflatoxin B2 alpha increases methylation ISO RGD:1316385 6480464 aflatoxin B2 results in increased methylation of BRD4 intron CTD PMID:30157460 atrazine increases expression ISO RGD:1316385 6480464 Atrazine results in increased expression of BRD4 mRNA CTD PMID:22378314 benzo[a]pyrene increases expression ISO RGD:1316386 6480464 Benzo(a)pyrene results in increased expression of BRD4 mRNA CTD PMID:22228805 benzo[a]pyrene decreases methylation ISO RGD:1316385 6480464 Benzo(a)pyrene results in decreased methylation of BRD4 5' UTR, Benzo(a)pyrene results in decreased methylation of BRD4 exon CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:1316385 6480464 Benzo(a)pyrene affects the methylation of BRD4 promoter CTD PMID:27901495 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of BRD4 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO RGD:1316385 6480464 bisphenol A results in increased methylation of BRD4 gene CTD PMID:31601247 bisphenol A decreases expression ISO RGD:1316386 6480464 bisphenol A results in decreased expression of BRD4 mRNA CTD PMID:33221593 bisphenol F multiple interactions ISO RGD:1316385 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of BRD4 gene CTD PMID:31601247 buta-1,3-diene decreases expression ISO RGD:1316386 6480464 1, 3-butadiene results in decreased expression of BRD4 mRNA CTD PMID:29038090 cadmium atom multiple interactions ISO RGD:1316385 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BRD4 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO RGD:1316385 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BRD4 mRNA CTD PMID:35301059 caffeine decreases phosphorylation ISO RGD:1316385 6480464 Caffeine results in decreased phosphorylation of BRD4 protein CTD PMID:35688186 carfilzomib multiple interactions ISO RGD:1316385 6480464 carfilzomib inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein] CTD PMID:26051217 ceruletide multiple interactions ISO RGD:1316386 6480464 (+)-JQ1 compound inhibits the reaction [[KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein], [KRAS protein mutant form co-treated with Ceruletide] results in increased expression of BRD4 protein CTD PMID:26390243 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of BRD4 mRNA CTD PMID:23125180 cisplatin decreases expression ISO RGD:1316385 6480464 Cisplatin results in decreased expression of BRD4 mRNA CTD PMID:27392435 , PMID:27594783 cocaine multiple interactions ISO RGD:1316386 6480464 (+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]], Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter] CTD PMID:26558777 cocaine increases expression ISO RGD:1316386 6480464 Cocaine results in increased expression of BRD4 protein CTD PMID:26558777 cocaine increases expression EXP 6480464 Cocaine results in increased expression of BRD4 protein CTD PMID:26558777 coumarin decreases phosphorylation ISO RGD:1316385 6480464 coumarin results in decreased phosphorylation of BRD4 protein CTD PMID:35688186 cyclosporin A increases expression ISO RGD:1316385 6480464 Cyclosporine results in increased expression of BRD4 mRNA CTD PMID:25562108 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of BRD4 mRNA CTD PMID:23640034 dibenzo[a,l]pyrene increases expression ISO RGD:1316386 6480464 dibenzo(a, l)pyrene results in increased expression of BRD4 mRNA CTD PMID:25908611 dicrotophos increases expression ISO RGD:1316385 6480464 dicrotophos results in increased expression of BRD4 mRNA CTD PMID:28302478 dioxygen increases expression ISO RGD:1316386 6480464 Oxygen deficiency results in increased expression of BRD4 mRNA CTD PMID:24205000 dioxygen increases expression ISO RGD:1316385 6480464 Oxygen deficiency results in increased expression of BRD4 CTD PMID:27292261 dioxygen multiple interactions ISO RGD:1316385 6480464 Oxygen deficiency promotes the reaction [BRD4 protein binds to CA9 promoter], Oxygen deficiency promotes the reaction [BRD4 protein binds to VEGFA promoter] CTD PMID:27292261 diuron decreases expression EXP 6480464 Diuron results in decreased expression of BRD4 mRNA CTD PMID:25152437 dorsomorphin multiple interactions ISO RGD:1316385 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BRD4 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1316385 6480464 Doxorubicin results in decreased expression of BRD4 mRNA CTD PMID:29803840 enzyme inhibitor multiple interactions ISO RGD:1316385 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of BRD4 protein CTD PMID:23301498 ethanol affects splicing ISO RGD:1316386 6480464 Ethanol affects the splicing of BRD4 mRNA CTD PMID:30319688 everolimus multiple interactions ISO RGD:1316385 6480464 [MYC protein results in decreased susceptibility to Everolimus] promotes the reaction [BRD4 protein binds to MYC gene] CTD PMID:25537515 flutamide increases expression EXP 6480464 Flutamide results in increased expression of BRD4 mRNA CTD PMID:20566332 folic acid decreases expression ISO RGD:1316385 6480464 Folic Acid results in decreased expression of BRD4 mRNA CTD PMID:21867686 fulvestrant multiple interactions ISO RGD:1316385 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of BRD4 gene CTD PMID:31601247 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of BRD4 mRNA CTD PMID:22061828 glyphosate increases expression EXP 6480464 glyphosate results in increased expression of BRD4 mRNA CTD PMID:26302742 glyphosate increases methylation EXP 6480464 glyphosate results in increased methylation of BRD4 gene CTD PMID:31011160 hydrogen peroxide multiple interactions ISO RGD:1316385 6480464 (+)-JQ1 compound inhibits the reaction [[Hydrogen Peroxide co-treated with IL1B protein] promotes the reaction [BRD4 protein binds to CXCL8 promoter]] more ... CTD PMID:24759736 hypochlorous acid decreases expression ISO RGD:1316386 6480464 Hypochlorous Acid results in decreased expression of BRD4 mRNA CTD PMID:19376150 immunological adjuvant increases expression ISO RGD:1316386 6480464 Adjuvants, Immunologic results in increased expression of BRD4 mRNA CTD PMID:25656449 isoprenaline decreases expression ISO RGD:1316386 6480464 Isoproterenol results in decreased expression of BRD4 mRNA CTD PMID:20003209 ivermectin decreases expression ISO RGD:1316385 6480464 Ivermectin results in decreased expression of BRD4 protein CTD PMID:32959892 leflunomide increases expression ISO RGD:1316385 6480464 leflunomide results in increased expression of BRD4 mRNA CTD PMID:28988120 lipopolysaccharide multiple interactions ISO RGD:1316386 6480464 GSK1210151A inhibits the reaction [[Lipopolysaccharides results in increased acetylation of RELA protein] which binds to BRD4 protein] CTD PMID:25778533 methylmercury chloride increases expression ISO RGD:1316385 6480464 methylmercuric chloride results in increased expression of BRD4 mRNA CTD PMID:23179753 , PMID:26272509 methylmercury chloride multiple interactions ISO RGD:1316385 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BRD4 mRNA CTD PMID:27188386 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1316385 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein], benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein] CTD PMID:23686307 , PMID:26051217 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1316386 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]] CTD PMID:25877301 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of BRD4 mRNA CTD PMID:22124623 paracetamol decreases expression ISO RGD:1316385 6480464 Acetaminophen results in decreased expression of BRD4 mRNA CTD PMID:26690555 pentachlorophenol increases expression ISO RGD:1316386 6480464 Pentachlorophenol results in increased expression of BRD4 mRNA CTD PMID:23892564 perfluorooctanoic acid decreases expression ISO RGD:1316385 6480464 perfluorooctanoic acid results in decreased expression of BRD4 protein CTD PMID:26879310 phenylephrine multiple interactions EXP 6480464 Phenylephrine promotes the reaction [BRD4 protein binds to NPPA promoter] CTD PMID:23939492 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of BRD4 protein CTD PMID:23939492 pirinixic acid increases expression ISO RGD:1316386 6480464 pirinixic acid results in increased expression of BRD4 mRNA CTD PMID:18445702 pomalidomide multiple interactions ISO RGD:1316385 6480464 pomalidomide inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein] CTD PMID:26051217 SB 431542 multiple interactions ISO RGD:1316385 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of BRD4 mRNA CTD PMID:27188386 Soman increases expression EXP 6480464 Soman results in increased expression of BRD4 mRNA CTD PMID:19281266 sulindac decreases expression ISO RGD:1316385 6480464 Sulindac results in decreased expression of BRD4 mRNA CTD PMID:11906190 sunitinib increases expression ISO RGD:1316385 6480464 Sunitinib results in increased expression of BRD4 mRNA CTD PMID:31533062 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of BRD4 mRNA CTD PMID:34492290 triptonide affects expression ISO RGD:1316386 6480464 triptonide affects the expression of BRD4 mRNA CTD PMID:33045310 troglitazone decreases expression ISO RGD:1316386 6480464 troglitazone results in decreased expression of BRD4 mRNA CTD PMID:28973697 tungsten decreases expression ISO RGD:1316386 6480464 Tungsten results in decreased expression of BRD4 mRNA CTD PMID:30912803 urethane increases expression ISO RGD:1316385 6480464 Urethane results in increased expression of BRD4 mRNA CTD PMID:28818685 valproic acid affects expression ISO RGD:1316386 6480464 Valproic Acid affects the expression of BRD4 mRNA CTD PMID:17292431 valproic acid increases expression ISO RGD:1316385 6480464 Valproic Acid results in increased expression of BRD4 mRNA CTD PMID:23179753 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of BRD4 mRNA CTD PMID:19015723 vorinostat decreases expression ISO RGD:1316385 6480464 vorinostat results in decreased expression of BRD4 mRNA CTD PMID:27188386
