Mbd3 (methyl-CpG binding domain protein 3) - Rat Genome Database

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Gene: Mbd3 (methyl-CpG binding domain protein 3) Rattus norvegicus
Analyze
Symbol: Mbd3
Name: methyl-CpG binding domain protein 3
RGD ID: 1307389
Description: Predicted to enable chromatin binding activity and methyl-CpG binding activity. Involved in several processes, including aging; regulation of DNA methylation; and response to estradiol. Predicted to be located in cytoplasm; heterochromatin; and nucleus. Predicted to be part of NuRD complex. Biomarker of transient cerebral ischemia and visual epilepsy. Orthologous to human MBD3 (methyl-CpG binding domain protein 3); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362834; methyl-CpG-binding domain protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Mbd3l2  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.279,312,961 - 9,320,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,313,098 - 9,320,165 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,189,440 - 12,196,639 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0714,064,780 - 14,071,979 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0711,932,473 - 11,939,678 (+)NCBIRnor_WKY
Rnor_6.0712,179,046 - 12,186,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,179,203 - 12,186,656 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,349,101 - 12,356,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,824,260 - 10,831,460 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,824,538 - 10,830,878 (+)NCBI
Celera77,491,653 - 7,498,865 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The nucleosome remodeling and deacetylase complex in development and disease. Basta J and Rauchman M, Transl Res. 2014 May 10. pii: S1931-5244(14)00166-2. doi: 10.1016/j.trsl.2014.05.003.
2. Kindling induces the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus. Francis J, etal., Neuroscience. 2002;113(1):79-87.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. A folate- and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats. Ghoshal K, etal., J Nutr. 2006 Jun;136(6):1522-7.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Differential expression of methyl CpG-binding domain containing factor MBD3 in the developing and adult rat brain. Jung BP, etal., J Neurobiol. 2003 May;55(2):220-32.
7. Transient forebrain ischemia alters the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus. Jung BP, etal., Neuroscience. 2002;115(2):515-24.
8. Epigenetic regulation of neonatal cardiomyocytes differentiation. Kou CY, etal., Biochem Biophys Res Commun. 2010 Sep 17;400(2):278-83. doi: 10.1016/j.bbrc.2010.08.064. Epub 2010 Aug 22.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life. Tang WY, etal., Endocrinology. 2012 Jan;153(1):42-55. doi: 10.1210/en.2011-1308. Epub 2011 Nov 22.
Additional References at PubMed
PMID:9774669   PMID:12477932   PMID:14643676   PMID:16217013   PMID:16322236   PMID:16462733   PMID:17287250   PMID:17546630   PMID:19796622   PMID:20720167   PMID:22770845   PMID:24307175  
PMID:24991957   PMID:27650712  


Genomics

Comparative Map Data
Mbd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.279,312,961 - 9,320,166 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,313,098 - 9,320,165 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,189,440 - 12,196,639 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0714,064,780 - 14,071,979 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0711,932,473 - 11,939,678 (+)NCBIRnor_WKY
Rnor_6.0712,179,046 - 12,186,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,179,203 - 12,186,656 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,349,101 - 12,356,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,824,260 - 10,831,460 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,824,538 - 10,830,878 (+)NCBI
Celera77,491,653 - 7,498,865 (+)NCBICelera
Cytogenetic Map7q11NCBI
MBD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,573,596 - 1,592,865 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl191,573,596 - 1,592,865 (-)EnsemblGRCh38hg38GRCh38
GRCh37191,573,595 - 1,592,864 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,527,678 - 1,543,652 (-)NCBINCBI36Build 36hg18NCBI36
Build 34191,527,677 - 1,543,652NCBI
Celera191,511,530 - 1,527,508 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,350,749 - 1,366,844 (-)NCBIHuRef
CHM1_1191,576,471 - 1,592,573 (-)NCBICHM1_1
T2T-CHM13v2.0191,544,415 - 1,563,688 (-)NCBIT2T-CHM13v2.0
Mbd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,228,373 - 80,235,365 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,228,373 - 80,235,384 (-)EnsemblGRCm39 Ensembl
GRCm381080,392,539 - 80,399,531 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,392,539 - 80,399,550 (-)EnsemblGRCm38mm10GRCm38
MGSCv371079,855,286 - 79,862,224 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,795,670 - 79,802,608 (-)NCBIMGSCv36mm8
Celera1081,409,909 - 81,416,847 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Mbd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,336,367 - 6,389,056 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,385,449 - 6,388,911 (+)NCBIChiLan1.0ChiLan1.0
MBD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1191,549,184 - 1,565,601 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl191,549,184 - 1,559,254 (-)Ensemblpanpan1.1panPan2
MBD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,296,713 - 57,312,988 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,296,713 - 57,307,110 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,088,646 - 57,104,853 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,027,199 - 58,043,634 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,027,121 - 58,039,063 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,084,174 - 57,100,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,563,503 - 57,579,656 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,765,346 - 57,781,556 (+)NCBIUU_Cfam_GSD_1.0
Mbd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,960,330 - 216,969,737 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588864,867 - 874,923 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936588865,046 - 873,821 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MBD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,906,644 - 76,923,432 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,913,880 - 76,923,435 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,156,278 - 78,165,819 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MBD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,357,388 - 1,371,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl61,357,204 - 1,371,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660817,475,254 - 7,491,681 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mbd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,132,274 - 7,144,964 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,132,228 - 7,144,599 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mbd3
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:202
Count of miRNA genes:126
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000049170
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat

Markers in Region
RH126839  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2225,501,662 - 25,501,882 (+)MAPPERmRatBN7.2
mRatBN7.279,319,929 - 9,320,149 (+)MAPPERmRatBN7.2
Rnor_6.0223,926,119 - 23,926,338NCBIRnor6.0
Rnor_6.0712,186,015 - 12,186,234NCBIRnor6.0
Rnor_5.0712,356,070 - 12,356,289UniSTSRnor5.0
Rnor_5.0243,097,162 - 43,097,381UniSTSRnor5.0
RGSC_v3.4224,571,860 - 24,572,079UniSTSRGSC3.4
RGSC_v3.4710,831,227 - 10,831,446UniSTSRGSC3.4
Celera77,498,632 - 7,498,851UniSTS
Celera221,573,686 - 21,573,905UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map2q12UniSTS
RH133854  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2225,501,655 - 25,501,870 (+)MAPPERmRatBN7.2
mRatBN7.279,319,922 - 9,320,137 (+)MAPPERmRatBN7.2
Rnor_6.0223,926,112 - 23,926,326NCBIRnor6.0
Rnor_6.0712,186,008 - 12,186,222NCBIRnor6.0
Rnor_5.0712,356,063 - 12,356,277UniSTSRnor5.0
Rnor_5.0243,097,155 - 43,097,369UniSTSRnor5.0
RGSC_v3.4224,571,853 - 24,572,067UniSTSRGSC3.4
RGSC_v3.4710,831,220 - 10,831,434UniSTSRGSC3.4
Celera77,498,625 - 7,498,839UniSTS
Celera221,573,679 - 21,573,893UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map2q12UniSTS
BE121221  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.279,312,170 - 9,312,327 (+)MAPPERmRatBN7.2
Rnor_6.0712,178,256 - 12,178,412NCBIRnor6.0
Rnor_5.0712,348,311 - 12,348,467UniSTSRnor5.0
RGSC_v3.4710,823,470 - 10,823,626UniSTSRGSC3.4
Celera77,490,863 - 7,491,019UniSTS
RH 3.4 Map727.7UniSTS
Cytogenetic Map7q11UniSTS
Mbd3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2225,501,527 - 25,501,865 (+)MAPPERmRatBN7.2
mRatBN7.279,319,794 - 9,320,132 (+)MAPPERmRatBN7.2
Rnor_6.0223,925,984 - 23,926,321NCBIRnor6.0
Rnor_6.0712,185,880 - 12,186,217NCBIRnor6.0
Rnor_5.0712,355,935 - 12,356,272UniSTSRnor5.0
Rnor_5.0243,097,027 - 43,097,364UniSTSRnor5.0
RGSC_v3.4224,571,725 - 24,572,062UniSTSRGSC3.4
RGSC_v3.4710,831,092 - 10,831,429UniSTSRGSC3.4
Celera77,498,497 - 7,498,834UniSTS
Celera221,573,551 - 21,573,888UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map2q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 48 33 19 33 6 9 74 35 41 11 6
Low 8 9 8 8 2 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000049170   ⟹   ENSRNOP00000041242
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,313,098 - 9,320,158 (+)Ensembl
Rnor_6.0 Ensembl712,179,203 - 12,186,656 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100050   ⟹   ENSRNOP00000094795
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,316,921 - 9,320,165 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103593   ⟹   ENSRNOP00000094225
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl79,316,821 - 9,320,165 (+)Ensembl
RefSeq Acc Id: NM_001108735   ⟹   NP_001102205
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,312,961 - 9,320,163 (+)NCBI
Rnor_6.0712,179,046 - 12,186,248 (+)NCBI
Rnor_5.0712,349,101 - 12,356,306 (+)NCBI
RGSC_v3.4710,824,260 - 10,831,460 (+)RGD
Celera77,491,653 - 7,498,865 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240965   ⟹   XP_006241027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,312,966 - 9,320,166 (+)NCBI
Rnor_6.0712,179,052 - 12,186,251 (+)NCBI
Rnor_5.0712,349,101 - 12,356,306 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240966   ⟹   XP_006241028
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,312,972 - 9,320,166 (+)NCBI
Rnor_6.0712,179,057 - 12,186,251 (+)NCBI
Rnor_5.0712,349,101 - 12,356,306 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765119   ⟹   XP_008763341
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,313,113 - 9,320,166 (+)NCBI
Rnor_6.0712,179,119 - 12,186,251 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765120   ⟹   XP_008763342
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,313,119 - 9,320,166 (+)NCBI
Rnor_6.0712,179,222 - 12,186,251 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765121   ⟹   XP_008763343
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,313,105 - 9,320,166 (+)NCBI
Rnor_6.0712,179,190 - 12,186,251 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079396   ⟹   XP_038935324
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,313,119 - 9,320,166 (+)NCBI
RefSeq Acc Id: XM_039079398   ⟹   XP_038935326
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,313,119 - 9,320,166 (+)NCBI
RefSeq Acc Id: XM_039079400   ⟹   XP_038935328
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.279,312,997 - 9,320,166 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001102205   ⟸   NM_001108735
- Sequence:
RefSeq Acc Id: XP_006241027   ⟸   XM_006240965
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006241028   ⟸   XM_006240966
- Peptide Label: isoform X8
- UniProtKB: F7EY92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763343   ⟸   XM_008765121
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008763341   ⟸   XM_008765119
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008763342   ⟸   XM_008765120
- Peptide Label: isoform X5
- UniProtKB: F7EY92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000041242   ⟸   ENSRNOT00000049170
RefSeq Acc Id: XP_038935328   ⟸   XM_039079400
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038935326   ⟸   XM_039079398
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038935324   ⟸   XM_039079396
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000094795   ⟸   ENSRNOT00000100050
RefSeq Acc Id: ENSRNOP00000094225   ⟸   ENSRNOT00000103593
Protein Domains
MBD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7EY92-F1-model_v2 AlphaFold F7EY92 1-254 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695019
Promoter ID:EPDNEW_R5544
Type:initiation region
Name:Mbd3_1
Description:methyl-CpG binding domain protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0712,179,117 - 12,179,177EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307389 AgrOrtholog
BioCyc Gene G2FUF-34941 BioCyc
Ensembl Genes ENSRNOG00000028956 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041242 ENTREZGENE
  ENSRNOP00000041242.6 UniProtKB/TrEMBL
  ENSRNOP00000094225 ENTREZGENE
  ENSRNOP00000094225.1 UniProtKB/TrEMBL
  ENSRNOP00000094795.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000049170 ENTREZGENE
  ENSRNOT00000049170.6 UniProtKB/TrEMBL
  ENSRNOT00000100050.1 UniProtKB/TrEMBL
  ENSRNOT00000103593 ENTREZGENE
  ENSRNOT00000103593.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8363656 IMAGE-MGC_LOAD
InterPro DNA-bd_integrase-typ UniProtKB/TrEMBL
  MBD2/MBD3_p55-bd UniProtKB/TrEMBL
  MBD3 UniProtKB/TrEMBL
  MeCpG_bd_2/3_C_dom UniProtKB/TrEMBL
  Methyl_CpG_DNA-bd UniProtKB/TrEMBL
MGC_CLONE MGC:189306 IMAGE-MGC_LOAD
NCBI Gene 362834 ENTREZGENE
PANTHER PTHR12396:SF12 UniProtKB/TrEMBL
Pfam MBD_C UniProtKB/TrEMBL
  MBDa UniProtKB/TrEMBL
PhenoGen Mbd3 PhenoGen
PROSITE MBD UniProtKB/TrEMBL
SMART MBD UniProtKB/TrEMBL
Superfamily-SCOP DNA-binding_integrase-type UniProtKB/TrEMBL
UniProt A0A8I6ANN7_RAT UniProtKB/TrEMBL
  A0A8I6GL26_RAT UniProtKB/TrEMBL
  B2RZ64_RAT UniProtKB/TrEMBL
  F7EY92 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mbd3  methyl-CpG binding domain protein 3   Mbd3_predicted  methyl-CpG binding domain protein 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mbd3_predicted  methyl-CpG binding domain protein 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED