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Gene: Mbd3 (methyl-CpG binding domain protein 3) Rattus norvegicus
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Symbol: Mbd3
Name: methyl-CpG binding domain protein 3
Description: Predicted to have chromatin binding activity and methyl-CpG binding activity. Involved in several processes, including animal organ development; regulation of DNA methylation; and response to estradiol. Predicted to localize to the NuRD complex; cytoplasm; and heterochromatin. Biomarker of transient cerebral ischemia and visual epilepsy. Orthologous to human MBD3 (methyl-CpG binding domain protein 3); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; INTERACTS WITH 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC362834; methyl-CpG-binding domain protein 3
Orthologs:
Homo sapiens (human) : MBD3 (methyl-CpG binding domain protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Mbd3 (methyl-CpG binding domain protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbd3 (methyl-CpG binding domain protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : MBD3 (methyl-CpG binding domain protein 3)
Canis lupus familiaris (dog) : MBD3 (methyl-CpG binding domain protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mbd3 (methyl-CpG binding domain protein 3)
Sus scrofa (pig) : MBD3 (methyl-CpG binding domain protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0712,179,046 - 12,186,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,179,203 - 12,186,656 (+)Ensembl
Rnor_5.0712,349,101 - 12,356,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,824,260 - 10,831,460 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1710,824,538 - 10,830,878 (+)NCBI
Celera77,491,653 - 7,498,865 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mbd3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307389
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.